Published in Proc Natl Acad Sci U S A on December 18, 2007
Heterosubtypic neutralizing monoclonal antibodies cross-protective against H5N1 and H1N1 recovered from human IgM+ memory B cells. PLoS One (2008) 6.98
The influenza virus enigma. Cell (2009) 2.48
Multiple reassortment between pandemic (H1N1) 2009 and endemic influenza viruses in pigs, United States. Emerg Infect Dis (2011) 2.42
The pig as a mixing vessel for influenza viruses: Human and veterinary implications. J Mol Genet Med (2008) 2.35
Reassortment between avian H5N1 and human H3N2 influenza viruses in ferrets: a public health risk assessment. J Virol (2009) 2.33
Diversity of influenza viruses in swine and the emergence of a novel human pandemic influenza A (H1N1). Influenza Other Respir Viruses (2009) 2.11
Design and performance of the CDC real-time reverse transcriptase PCR swine flu panel for detection of 2009 A (H1N1) pandemic influenza virus. J Clin Microbiol (2011) 1.96
Receptor specificity and transmission of H2N2 subtype viruses isolated from the pandemic of 1957. PLoS One (2010) 1.95
H5N1 influenza viruses: facts, not fear. Proc Natl Acad Sci U S A (2012) 1.94
Current and future antiviral therapy of severe seasonal and avian influenza. Antiviral Res (2008) 1.86
Different evolutionary trajectories of European avian-like and classical swine H1N1 influenza A viruses. J Virol (2009) 1.79
Functional balance of the hemagglutinin and neuraminidase activities accompanies the emergence of the 2009 H1N1 influenza pandemic. J Virol (2012) 1.76
Domestic pigs have low susceptibility to H5N1 highly pathogenic avian influenza viruses. PLoS Pathog (2008) 1.66
A recurring motif for antibody recognition of the receptor-binding site of influenza hemagglutinin. Nat Struct Mol Biol (2013) 1.60
Glycan analysis and influenza A virus infection of primary swine respiratory epithelial cells: the importance of NeuAc{alpha}2-6 glycans. J Biol Chem (2010) 1.53
Structure, receptor binding, and antigenicity of influenza virus hemagglutinins from the 1957 H2N2 pandemic. J Virol (2009) 1.50
Retracted Triple reassortant swine influenza A (H3N2) virus in waterfowl. Emerg Infect Dis (2010) 1.46
Continuing challenges in influenza. Ann N Y Acad Sci (2014) 1.43
Isolation and genetic characterization of H5N2 influenza viruses from pigs in Korea. J Virol (2009) 1.40
Pathogenesis and transmission of triple-reassortant swine H1N1 influenza viruses isolated before the 2009 H1N1 pandemic. J Virol (2010) 1.35
Viral reassortment and transmission after co-infection of pigs with classical H1N1 and triple-reassortant H3N2 swine influenza viruses. J Gen Virol (2010) 1.23
Evidence of reassortment of pandemic H1N1 influenza virus in swine in Argentina: are we facing the expansion of potential epicenters of influenza emergence? Influenza Other Respir Viruses (2011) 1.21
Human monoclonal antibodies to pandemic 1957 H2N2 and pandemic 1968 H3N2 influenza viruses. J Virol (2012) 1.20
Determinants of glycan receptor specificity of H2N2 influenza A virus hemagglutinin. PLoS One (2010) 1.20
Reverse zoonosis of influenza to swine: new perspectives on the human-animal interface. Trends Microbiol (2015) 1.19
A 27-amino-acid deletion in the neuraminidase stalk supports replication of an avian H2N2 influenza A virus in the respiratory tract of chickens. J Virol (2010) 1.18
Influenza viruses: breaking all the rules. MBio (2013) 1.14
Reassortment patterns in Swine influenza viruses. PLoS One (2009) 1.13
Modifications in the polymerase genes of a swine-like triple-reassortant influenza virus to generate live attenuated vaccines against 2009 pandemic H1N1 viruses. J Virol (2010) 1.09
Evaluation of replication and cross-reactive antibody responses of H2 subtype influenza viruses in mice and ferrets. J Virol (2010) 1.06
Host adaptation and transmission of influenza A viruses in mammals. Emerg Microbes Infect (2014) 1.06
Industrial food animal production and global health risks: exploring the ecosystems and economics of avian influenza. Ecohealth (2009) 1.03
The neuraminidase and matrix genes of the 2009 pandemic influenza H1N1 virus cooperate functionally to facilitate efficient replication and transmissibility in pigs. J Gen Virol (2012) 1.02
Risk assessment of H2N2 influenza viruses from the avian reservoir. J Virol (2013) 0.99
Novel Reassortant Human-Like H3N2 and H3N1 Influenza A Viruses Detected in Pigs Are Virulent and Antigenically Distinct from Swine Viruses Endemic to the United States. J Virol (2015) 0.99
Pathogenicity and transmissibility of reassortant H9 influenza viruses with genes from pandemic H1N1 virus. J Gen Virol (2012) 0.93
2009 pandemic H1N1 influenza virus causes disease and upregulation of genes related to inflammatory and immune responses, cell death, and lipid metabolism in pigs. J Virol (2011) 0.89
A review of influenza haemagglutinin receptor binding as it relates to pandemic properties. Vaccine (2012) 0.88
Pathogenicity of swine influenza viruses possessing an avian or swine-origin PB2 polymerase gene evaluated in mouse and pig models. Virology (2010) 0.88
Characterization of a novel reassortant influenza A virus (H2N2) from a domestic duck in Eastern China. Sci Rep (2014) 0.87
Model or meal? Farm animal populations as models for infectious diseases of humans. Nat Rev Microbiol (2009) 0.87
Serologic survey of swine workers for exposure to H2N3 swine influenza A. Influenza Other Respir Viruses (2010) 0.87
Domestic pigs are susceptible to infection with influenza B viruses. J Virol (2015) 0.86
The receptor binding specificity of the live attenuated influenza H2 and H6 vaccine viruses contributes to vaccine immunogenicity and protection in ferrets. J Virol (2011) 0.86
Development and pre-clinical evaluation of two LAIV strains against potentially pandemic H2N2 influenza virus. PLoS One (2014) 0.84
Recently emerged swine influenza A virus (H2N3) causes severe pneumonia in Cynomolgus macaques. PLoS One (2012) 0.84
Differentiated swine airway epithelial cell cultures for the investigation of influenza A virus infection and replication. Influenza Other Respir Viruses (2012) 0.84
H2N2 live attenuated influenza vaccine is safe and immunogenic for healthy adult volunteers. Hum Vaccin Immunother (2015) 0.84
Epidemic status of Swine influenza virus in china. Indian J Microbiol (2013) 0.84
Significant neutralizing activities against H2N2 influenza A viruses in human intravenous immunoglobulin lots manufactured from 1993 to 2010. Biologics (2012) 0.84
Reassortment patterns in Swine influenza viruses. PLoS Curr (2009) 0.84
Optimal Use of Vaccines for Control of Influenza A Virus in Swine. Vaccines (Basel) (2015) 0.83
The modes of evolutionary emergence of primal and late pandemic influenza virus strains from viral reservoir in animals: an interdisciplinary analysis. Influenza Res Treat (2011) 0.83
Human H7N9 influenza A viruses replicate in swine respiratory tissue explants. J Virol (2013) 0.82
Evaluation of three live attenuated H2 pandemic influenza vaccine candidates in mice and ferrets. J Virol (2013) 0.81
Functional and structural analysis of influenza virus neuraminidase N3 offers further insight into the mechanisms of oseltamivir resistance. J Virol (2013) 0.80
Pathogenicity and transmissibility of novel reassortant H3N2 influenza viruses with 2009 pandemic H1N1 genes in pigs. J Virol (2014) 0.80
A possible outbreak of swine influenza, 1892. Lancet Infect Dis (2013) 0.80
Detecting transmission and reassortment events for influenza A viruses with genotype profile method. Virol J (2011) 0.79
Rapid detection of the pandemic 2009 H1N1 virus M gene by real-time and gel-based RT-PCR assays. Influenza Other Respir Viruses (2010) 0.78
H1N1 Swine Influenza Viruses Differ from Avian Precursors by a Higher pH Optimum of Membrane Fusion. J Virol (2015) 0.76
Replication of live attenuated cold-adapted H2N2 influenza virus vaccine candidates in non human primates. Vaccine (2014) 0.76
Infectivity phenotypes of H3N2 influenza A viruses in primary swine respiratory epithelial cells are controlled by sialic acid binding. Influenza Other Respir Viruses (2012) 0.76
Pandemism of swine flu and its prospective drug therapy. Eur J Clin Microbiol Infect Dis (2012) 0.76
Epidemiological features of influenza circulation in swine populations: A systematic review and meta-analysis. PLoS One (2017) 0.75
Evaluation of multivalent H2 influenza pandemic vaccines in mice. Vaccine (2017) 0.75
Genetic Analysis of Avian Influenza Viruses: Cocirculation of Avian Influenza Viruses with Allele A and B Nonstructural Gene in Northern Pintail (Anas acuta) Ducks Wintering in Japan. Influenza Res Treat (2012) 0.75
A peptide-based approach to evaluate the adaptability of influenza A virus to humans based on its hemagglutinin proteolytic cleavage site. PLoS One (2017) 0.75
Control of a Reassortant Pandemic 2009 H1N1 Influenza Virus Outbreak in an Intensive Swine Breeding Farm: Effect of Vaccination and Enhanced Farm Management Practices. PLoS Curr (2015) 0.75
Role of Substitutions in the Hemagglutinin in the Emergence of the 1968 Pandemic Influenza Virus. J Virol (2015) 0.75
Virologic Differences Do Not Fully Explain the Diversification of Swine Influenza Viruses in the United States. J Virol (2016) 0.75
CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice. Nucleic Acids Res (1994) 392.47
Evolution and ecology of influenza A viruses. Microbiol Rev (1992) 39.99
Universal primer set for the full-length amplification of all influenza A viruses. Arch Virol (2001) 21.17
Avian flu: influenza virus receptors in the human airway. Nature (2006) 11.28
Avian-to-human transmission of the PB1 gene of influenza A viruses in the 1957 and 1968 pandemics. J Virol (1989) 10.63
Molecular basis for the generation in pigs of influenza A viruses with pandemic potential. J Virol (1998) 8.44
A two-amino acid change in the hemagglutinin of the 1918 influenza virus abolishes transmission. Science (2007) 8.38
Single amino acid substitutions in influenza haemagglutinin change receptor binding specificity. Nature (1983) 8.28
Early alterations of the receptor-binding properties of H1, H2, and H3 avian influenza virus hemagglutinins after their introduction into mammals. J Virol (2000) 8.28
Receptor specificity in human, avian, and equine H2 and H3 influenza virus isolates. Virology (1994) 8.06
Spatial, temporal, and species variation in prevalence of influenza A viruses in wild migratory birds. PLoS Pathog (2007) 6.04
Avian influenza A viruses differ from human viruses by recognition of sialyloligosaccharides and gangliosides and by a higher conservation of the HA receptor-binding site. Virology (1997) 4.96
Influenza A viruses of migrating wild aquatic birds in North America. Vector Borne Zoonotic Dis (2004) 4.89
Genetic reassortment between avian and human influenza A viruses in Italian pigs. Virology (1993) 4.40
Origin of the pandemic 1957 H2 influenza A virus and the persistence of its possible progenitors in the avian reservoir. Virology (1993) 3.54
Immunization with reverse-genetics-produced H5N1 influenza vaccine protects ferrets against homologous and heterologous challenge. J Infect Dis (2006) 3.28
Host range restriction and pathogenicity in the context of influenza pandemic. Emerg Infect Dis (2006) 3.27
Persistence of H5 and H7 avian influenza viruses in water. Avian Dis (2007) 3.17
Isolation and characterization of H4N6 avian influenza viruses from pigs with pneumonia in Canada. J Virol (2000) 3.14
Pathogenic and antigenic properties of phylogenetically distinct reassortant H3N2 swine influenza viruses cocirculating in the United States. J Clin Microbiol (2003) 2.55
Influenza: emergence and control. J Virol (2004) 2.31
Quail carry sialic acid receptors compatible with binding of avian and human influenza viruses. Virology (2005) 2.17
Ferrets as a transmission model for influenza: sequence changes in HA1 of type A (H3N2) virus. J Infect Dis (2001) 2.11
The origin and virulence of the 1918 "Spanish" influenza virus. Proc Am Philos Soc (2006) 1.96
Transmission of Eurasian avian H2 influenza virus to shorebirds in North America. J Gen Virol (1999) 1.85
Characterization of avian H3N3 and H1N1 influenza A viruses isolated from pigs in Canada. J Clin Microbiol (2004) 1.78
Isolation and genetic characterization of new reassortant H3N1 swine influenza virus from pigs in the midwestern United States. J Virol (2006) 1.73
Application of a nested polymerase chain reaction assay to detect Mycoplasma hyopneumoniae from nasal swabs. J Vet Diagn Invest (1999) 1.68
The immune response and maternal antibody interference to a heterologous H1N1 swine influenza virus infection following vaccination. Vet Immunol Immunopathol (2006) 1.68
Novel swine influenza virus subtype H3N1, United States. Emerg Infect Dis (2006) 1.49
Interregional transmission of the internal protein genes of H2 influenza virus in migratory ducks from North America to Eurasia. Virus Genes (2004) 1.28
Molecular evolution of influenza viruses. Virus Genes (1995) 1.24
Real-time reverse transcription-polymerase chain reaction assays for the detection and differentiation of North American swine influenza viruses. J Vet Diagn Invest (2004) 1.18
Evaluation of a multiplex reverse transcription-polymerase chain reaction assay for subtyping hemagglutinin genes 1 and 3 of swine influenza type A virus in clinical samples. J Vet Diagn Invest (2002) 0.83
The polymerase complex genes contribute to the high virulence of the human H5N1 influenza virus isolate A/Vietnam/1203/04. J Exp Med (2006) 5.94
The intracellular sensor NLRP3 mediates key innate and healing responses to influenza A virus via the regulation of caspase-1. Immunity (2009) 4.51
Swine influenza viruses a North American perspective. Adv Virus Res (2008) 4.28
Dynamic T cell migration program provides resident memory within intestinal epithelium. J Exp Med (2010) 4.09
Isolation and characterization of porcine epidemic diarrhea viruses associated with the 2013 disease outbreak among swine in the United States. J Clin Microbiol (2013) 4.05
Gain-of-function experiments on H7N9. Science (2013) 3.67
MERS coronaviruses in dromedary camels, Egypt. Emerg Infect Dis (2014) 3.64
The genesis and source of the H7N9 influenza viruses causing human infections in China. Nature (2013) 3.60
Cross-reactive neuraminidase antibodies afford partial protection against H5N1 in mice and are present in unexposed humans. PLoS Med (2007) 3.57
Immunization with reverse-genetics-produced H5N1 influenza vaccine protects ferrets against homologous and heterologous challenge. J Infect Dis (2006) 3.28
The influenza virus gene pool in a poultry market in South central china. Virology (2003) 3.25
Influenza in migratory birds and evidence of limited intercontinental virus exchange. PLoS Pathog (2007) 2.94
Mutations in the NS1 protein of swine influenza virus impair anti-interferon activity and confer attenuation in pigs. J Virol (2005) 2.88
Studies of H5N1 influenza virus infection of pigs by using viruses isolated in Vietnam and Thailand in 2004. J Virol (2005) 2.56
Pathogenic and antigenic properties of phylogenetically distinct reassortant H3N2 swine influenza viruses cocirculating in the United States. J Clin Microbiol (2003) 2.55
H3N2 influenza virus transmission from swine to turkeys, United States. Emerg Infect Dis (2004) 2.53
Evaluation of hemagglutinin subtype 1 swine influenza viruses from the United States. Vet Microbiol (2006) 2.45
Multiple reassortment between pandemic (H1N1) 2009 and endemic influenza viruses in pigs, United States. Emerg Infect Dis (2011) 2.42
Long-term evolution and transmission dynamics of swine influenza A virus. Nature (2011) 2.39
Comparative sequence analysis of the symbiosis island of Mesorhizobium loti strain R7A. J Bacteriol (2002) 2.37
Avian flu: Gain-of-function experiments on H7N9. Nature (2013) 2.32
Influenza: emergence and control. J Virol (2004) 2.31
Full-Length Genome Sequence of Porcine Deltacoronavirus Strain USA/IA/2014/8734. Genome Announc (2014) 2.30
Pause on avian flu transmission research. Science (2012) 2.24
Adaptation of pandemic H1N1 influenza viruses in mice. J Virol (2010) 2.22
Passive immunoprophylaxis and therapy with humanized monoclonal antibody specific for influenza A H5 hemagglutinin in mice. Respir Res (2006) 2.15
Pathogenesis of Hong Kong H5N1 influenza virus NS gene reassortants in mice: the role of cytokines and B- and T-cell responses. J Gen Virol (2005) 2.15
Role of specific hemagglutinin amino acids in the immunogenicity and protection of H5N1 influenza virus vaccines. Proc Natl Acad Sci U S A (2005) 2.13
Changes in H5N1 influenza virus hemagglutinin receptor binding domain affect systemic spread. Proc Natl Acad Sci U S A (2008) 2.11
Diversity of influenza viruses in swine and the emergence of a novel human pandemic influenza A (H1N1). Influenza Other Respir Viruses (2009) 2.11
Host genetic variation affects resistance to infection with a highly pathogenic H5N1 influenza A virus in mice. J Virol (2009) 2.08
Hemagglutinin-neuraminidase balance confers respiratory-droplet transmissibility of the pandemic H1N1 influenza virus in ferrets. Proc Natl Acad Sci U S A (2011) 2.04
Characterization of a newly emerged genetic cluster of H1N1 and H1N2 swine influenza virus in the United States. Virus Genes (2009) 1.94
Indications that live poultry markets are a major source of human H5N1 influenza virus infection in China. J Virol (2011) 1.85
Efficacy of H5 influenza vaccines produced by reverse genetics in a lethal mouse model. J Infect Dis (2005) 1.83
Isolation of a novel swine influenza virus from Oklahoma in 2011 which is distantly related to human influenza C viruses. PLoS Pathog (2013) 1.83
The M segment of the 2009 new pandemic H1N1 influenza virus is critical for its high transmission efficiency in the guinea pig model. J Virol (2011) 1.82
Oseltamivir-resistant pandemic H1N1/2009 influenza virus possesses lower transmissibility and fitness in ferrets. PLoS Pathog (2010) 1.81
Respiratory viruses augment the adhesion of bacterial pathogens to respiratory epithelium in a viral species- and cell type-dependent manner. J Virol (2006) 1.78
Characterization of an influenza A virus isolated from pigs during an outbreak of respiratory disease in swine and people during a county fair in the United States. Vet Microbiol (2009) 1.77
Mucosal immune responses predict clinical outcomes during influenza infection independently of age and viral load. Am J Respir Crit Care Med (2014) 1.75
Inactivated seasonal influenza vaccines increase serum antibodies to the neuraminidase of pandemic influenza A(H1N1) 2009 virus in an age-dependent manner. J Infect Dis (2010) 1.70
Increased pathogenicity of a reassortant 2009 pandemic H1N1 influenza virus containing an H5N1 hemagglutinin. J Virol (2011) 1.69
Does pandemic A/H1N1 virus have the potential to become more pathogenic? MBio (2010) 1.68
The immune response and maternal antibody interference to a heterologous H1N1 swine influenza virus infection following vaccination. Vet Immunol Immunopathol (2006) 1.68
The polymerase acidic protein gene of influenza a virus contributes to pathogenicity in a mouse model. J Virol (2009) 1.68
Domestic pigs have low susceptibility to H5N1 highly pathogenic avian influenza viruses. PLoS Pathog (2008) 1.66
Evolution of novel reassortant A/H3N2 influenza viruses in North American swine and humans, 2009-2011. J Virol (2012) 1.64
Detection of respiratory viruses and subtype identification of influenza A viruses by GreeneChipResp oligonucleotide microarray. J Clin Microbiol (2007) 1.59
Naturally occurring swine influenza A virus PB1-F2 phenotypes that contribute to superinfection with Gram-positive respiratory pathogens. J Virol (2012) 1.57
Evolution and ecology of influenza A viruses. Curr Top Microbiol Immunol (2014) 1.57
Global transmission of influenza viruses from humans to swine. J Gen Virol (2012) 1.55
Avian influenza viruses in Korean live poultry markets and their pathogenic potential. Virology (2005) 1.54
Coincident ruddy turnstone migration and horseshoe crab spawning creates an ecological 'hot spot' for influenza viruses. Proc Biol Sci (2010) 1.53
The epidemiological and molecular aspects of influenza H5N1 viruses at the human-animal interface in Egypt. PLoS One (2011) 1.51
Novel swine influenza virus subtype H3N1, United States. Emerg Infect Dis (2006) 1.49
Genotype patterns of contemporary reassorted H3N2 virus in US swine. J Gen Virol (2013) 1.49
Genetic and antigenic characterization of H1 influenza viruses from United States swine from 2008. J Gen Virol (2010) 1.48
Vaccination of pigs against swine influenza viruses by using an NS1-truncated modified live-virus vaccine. J Virol (2006) 1.48
Pandemic swine-origin H1N1 influenza A virus isolates show heterogeneous virulence in macaques. J Virol (2010) 1.47
Retracted Triple reassortant swine influenza A (H3N2) virus in waterfowl. Emerg Infect Dis (2010) 1.46
The feasibility of using high resolution genome sequencing of influenza A viruses to detect mixed infections and quasispecies. PLoS One (2009) 1.46
Continuing evolution of H9 influenza viruses in Korean poultry. Virology (2006) 1.45
Efficacy of intranasal administration of a truncated NS1 modified live influenza virus vaccine in swine. Vaccine (2007) 1.45
Recipients of vaccine against the 1976 "swine flu" have enhanced neutralization responses to the 2009 novel H1N1 influenza virus. Clin Infect Dis (2010) 1.44
Vaccine-induced anti-HA2 antibodies promote virus fusion and enhance influenza virus respiratory disease. Sci Transl Med (2013) 1.44
Inflammasome-independent role of the apoptosis-associated speck-like protein containing CARD (ASC) in the adjuvant effect of MF59. Proc Natl Acad Sci U S A (2011) 1.43
Influenza virus infection in racing greyhounds. Emerg Infect Dis (2005) 1.41
Matrix gene of influenza a viruses isolated from wild aquatic birds: ecology and emergence of influenza a viruses. J Virol (2004) 1.41
Isolation and genetic characterization of H5N2 influenza viruses from pigs in Korea. J Virol (2009) 1.40
The immunogenicity and efficacy against H5N1 challenge of reverse genetics-derived H5N3 influenza vaccine in ducks and chickens. Virology (2006) 1.39
NFkappaB negatively regulates interferon-induced gene expression and anti-influenza activity. J Biol Chem (2006) 1.38
Emergence of novel reassortant H3N2 swine influenza viruses with the 2009 pandemic H1N1 genes in the United States. Arch Virol (2011) 1.37
Genotype turnover by reassortment of replication complex genes from avian influenza A virus. J Gen Virol (2006) 1.37