Published in Annu Rev Psychol on January 01, 2008
Neurocircuitry of addiction. Neuropsychopharmacology (2010) 14.22
A role for brain stress systems in addiction. Neuron (2008) 4.71
The rostromedial tegmental nucleus (RMTg), a GABAergic afferent to midbrain dopamine neurons, encodes aversive stimuli and inhibits motor responses. Neuron (2009) 4.12
A multistep general theory of transition to addiction. Psychopharmacology (Berl) (2013) 4.01
The brain reward circuitry in mood disorders. Nat Rev Neurosci (2013) 3.08
Review. Neurobiological mechanisms for opponent motivational processes in addiction. Philos Trans R Soc Lond B Biol Sci (2008) 2.97
Cognitive neuroscience of self-regulation failure. Trends Cogn Sci (2011) 2.89
A unified framework for addiction: vulnerabilities in the decision process. Behav Brain Sci (2008) 2.83
The dynorphin/kappa opioid system as a modulator of stress-induced and pro-addictive behaviors. Brain Res (2009) 2.61
Disrupted ventromedial prefrontal function, alcohol craving, and subsequent relapse risk. JAMA Psychiatry (2013) 2.54
Reward processing by the opioid system in the brain. Physiol Rev (2009) 2.46
Metabotropic glutamate receptors: from the workbench to the bedside. Neuropharmacology (2010) 2.31
Implicit cognition and addiction: a tool for explaining paradoxical behavior. Annu Rev Clin Psychol (2010) 2.26
Serotonergic function, two-mode models of self-regulation, and vulnerability to depression: what depression has in common with impulsive aggression. Psychol Bull (2008) 2.24
Reward mechanisms in obesity: new insights and future directions. Neuron (2011) 2.21
Neurobiological substrates for the dark side of compulsivity in addiction. Neuropharmacology (2008) 2.16
Brain stress systems in the amygdala and addiction. Brain Res (2009) 2.14
Maternal high-fat diet alters methylation and gene expression of dopamine and opioid-related genes. Endocrinology (2010) 2.02
Obesity and addiction: neurobiological overlaps. Obes Rev (2012) 1.99
Acute withdrawal, protracted abstinence and negative affect in alcoholism: are they linked? Addict Biol (2010) 1.93
Role for mammalian target of rapamycin complex 1 signaling in neuroadaptations underlying alcohol-related disorders. Proc Natl Acad Sci U S A (2010) 1.88
DSM criteria for tobacco use disorder and tobacco withdrawal: a critique and proposed revisions for DSM-5. Addiction (2012) 1.81
Theoretical frameworks and mechanistic aspects of alcohol addiction: alcohol addiction as a reward deficit disorder. Curr Top Behav Neurosci (2013) 1.80
The development and maintenance of drug addiction. Neuropsychopharmacology (2013) 1.76
Neuroscience of self and self-regulation. Annu Rev Psychol (2011) 1.76
Pharmacogenetic approaches to the treatment of alcohol addiction. Nat Rev Neurosci (2011) 1.74
The behavioral economics of substance use disorders: reinforcement pathologies and their repair. Annu Rev Clin Psychol (2014) 1.74
The role of CRF and CRF-related peptides in the dark side of addiction. Brain Res (2009) 1.74
Cocaine drives aversive conditioning via delayed activation of dopamine-responsive habenular and midbrain pathways. J Neurosci (2013) 1.73
Reward circuitry dysfunction in psychiatric and neurodevelopmental disorders and genetic syndromes: animal models and clinical findings. J Neurodev Disord (2012) 1.73
Addiction as a stress surfeit disorder. Neuropharmacology (2013) 1.68
Chronic alcohol neuroadaptation and stress contribute to susceptibility for alcohol craving and relapse. Pharmacol Ther (2010) 1.62
Individual differences in prefrontal cortex function and the transition from drug use to drug dependence. Neurosci Biobehav Rev (2010) 1.61
Dynamics of neuronal circuits in addiction: reward, antireward, and emotional memory. Pharmacopsychiatry (2009) 1.57
Influence of affective manipulations on cigarette craving: a meta-analysis. Addiction (2013) 1.56
Influence of early life stress on later hypothalamic-pituitary-adrenal axis functioning and its covariation with mental health symptoms: a study of the allostatic process from childhood into adolescence. Dev Psychopathol (2011) 1.54
Alterations in brain structure and functional connectivity in prescription opioid-dependent patients. Brain (2010) 1.50
Aversive stimuli drive drug seeking in a state of low dopamine tone. Biol Psychiatry (2014) 1.50
Addiction science: Uncovering neurobiological complexity. Neuropharmacology (2013) 1.50
Neurobiological mechanisms of addiction: focus on corticotropin-releasing factor. Curr Opin Investig Drugs (2010) 1.49
Binge drinking upregulates accumbens mGluR5-Homer2-PI3K signaling: functional implications for alcoholism. J Neurosci (2009) 1.47
Dopamine signaling in the nucleus accumbens of animals self-administering drugs of abuse. Curr Top Behav Neurosci (2010) 1.46
Do patient-perceived pros and cons of opioids predict sustained higher-dose use? Clin J Pain (2014) 1.46
The neurobiology of food intake in an obesogenic environment. Proc Nutr Soc (2012) 1.43
Drug predictive cues activate aversion-sensitive striatal neurons that encode drug seeking. J Neurosci (2015) 1.41
Nicotine withdrawal increases threat-induced anxiety but not fear: neuroadaptation in human addiction. Biol Psychiatry (2010) 1.41
Addiction is Not a Brain Disease (and it Matters). Front Psychiatry (2013) 1.40
Activation instead of blocking mesolimbic dopaminergic reward circuitry is a preferred modality in the long term treatment of reward deficiency syndrome (RDS): a commentary. Theor Biol Med Model (2008) 1.35
Chronic high-fat diet drives postnatal epigenetic regulation of μ-opioid receptor in the brain. Neuropsychopharmacology (2011) 1.34
Repeated nitrous oxide exposure in rats causes a thermoregulatory sign-reversal with concurrent activation of opposing thermoregulatory effectors. Temperature (Austin) (2015) 1.34
Effects of stress on alcohol drinking: a review of animal studies. Psychopharmacology (Berl) (2011) 1.33
Food reward, hyperphagia, and obesity. Am J Physiol Regul Integr Comp Physiol (2011) 1.31
Intestinal permeability, gut-bacterial dysbiosis, and behavioral markers of alcohol-dependence severity. Proc Natl Acad Sci U S A (2014) 1.31
Internet and gaming addiction: a systematic literature review of neuroimaging studies. Brain Sci (2012) 1.30
Phasic dopamine release in appetitive behaviors and drug addiction. Curr Drug Abuse Rev (2009) 1.30
Development of pharmacotherapies for drug addiction: a Rosetta stone approach. Nat Rev Drug Discov (2009) 1.30
Internet gaming addiction: current perspectives. Psychol Res Behav Manag (2013) 1.29
Impact of bupropion and cognitive-behavioral treatment for depression on positive affect, negative affect, and urges to smoke during cessation treatment. Nicotine Tob Res (2009) 1.29
A proof-of-concept randomized controlled study of gabapentin: effects on cannabis use, withdrawal and executive function deficits in cannabis-dependent adults. Neuropsychopharmacology (2012) 1.29
Pharmacotherapy of amphetamine-type stimulant dependence: an update. Drug Alcohol Rev (2013) 1.29
Maternal smoking during pregnancy and neonatal behavior: a large-scale community study. Pediatrics (2009) 1.28
Clarifying the roles of homeostasis and allostasis in physiological regulation. Psychol Rev (2014) 1.23
The role of interoception and alliesthesia in addiction. Pharmacol Biochem Behav (2009) 1.22
Genetically correlated effects of selective breeding for high and low methamphetamine consumption. Genes Brain Behav (2009) 1.21
Mindfulness-based relapse prevention for substance craving. Addict Behav (2012) 1.21
The biology of binge eating. Appetite (2009) 1.19
Neural circuitry associated with risk for alcohol use disorders. Neuropsychol Rev (2009) 1.18
Increased extracellular glutamate in the nucleus accumbens promotes excessive ethanol drinking in ethanol dependent mice. Neuropsychopharmacology (2013) 1.17
Nicotine exposure during adolescence induces a depression-like state in adulthood. Neuropsychopharmacology (2008) 1.15
Allostasis model facilitates understanding race differences in the diurnal cortisol rhythm. Dev Psychopathol (2011) 1.14
Neurobiological mechanisms contributing to alcohol-stress-anxiety interactions. Alcohol (2009) 1.14
The downward spiral of chronic pain, prescription opioid misuse, and addiction: cognitive, affective, and neuropsychopharmacologic pathways. Neurosci Biobehav Rev (2013) 1.14
Neurobiology of dysregulated motivational systems in drug addiction. Future Neurol (2010) 1.14
Dissecting motivational circuitry to understand substance abuse. Neuropharmacology (2008) 1.14
Striatocortical pathway dysfunction in addiction and obesity: differences and similarities. Crit Rev Biochem Mol Biol (2012) 1.14
Synaptic effects induced by alcohol. Curr Top Behav Neurosci (2013) 1.13
From mouse to man: the 5-HT3 receptor modulates physical dependence on opioid narcotics. Pharmacogenet Genomics (2009) 1.11
Chromatin remodeling--a novel strategy to control excessive alcohol drinking. Transl Psychiatry (2013) 1.11
Psychological distress and smoking behavior: the nature of the relation differs by race/ethnicity. Nicotine Tob Res (2010) 1.10
The developmental psychopathology of alcohol use and alcohol disorders: research achievements and future directions. Dev Psychopathol (2013) 1.09
Effects of the mGlu2/3 agonist LY379268 and the mGlu5 antagonist MTEP on ethanol seeking and reinforcement are differentially altered in rats with a history of ethanol dependence. Biol Psychiatry (2010) 1.08
Pain and suicidality: insights from reward and addiction neuroscience. Prog Neurobiol (2013) 1.08
Hypocretin (orexin) facilitates reward by attenuating the antireward effects of its cotransmitter dynorphin in ventral tegmental area. Proc Natl Acad Sci U S A (2014) 1.08
Effects of methylphenidate on resting-state functional connectivity of the mesocorticolimbic dopamine pathways in cocaine addiction. JAMA Psychiatry (2013) 1.08
Alcohol stress response dampening: selective reduction of anxiety in the face of uncertain threat. J Psychopharmacol (2011) 1.07
White matter integrity is associated with treatment outcome measures in cocaine dependence. Neuropsychopharmacology (2010) 1.07
Levels of valence. Front Psychol (2013) 1.07
Allostasis and addiction: role of the dopamine and corticotropin-releasing factor systems. Physiol Behav (2011) 1.07
Behavioral stress may increase the rewarding valence of cocaine-associated cues through a dynorphin/kappa-opioid receptor-mediated mechanism without affecting associative learning or memory retrieval mechanisms. Neuropsychopharmacology (2010) 1.07
Trait-like impulsivity does not predict escalation of heroin self-administration in the rat. Psychopharmacology (Berl) (2010) 1.06
Development of mechanical hypersensitivity in rats during heroin and ethanol dependence: alleviation by CRF₁ receptor antagonism. Neuropharmacology (2011) 1.05
Brain region-specific gene expression changes after chronic intermittent ethanol exposure and early withdrawal in C57BL/6J mice. Addict Biol (2011) 1.05
The darkness within: individual differences in stress. Cerebrum (2015) 1.05
Early life protein restriction alters dopamine circuitry. Neuroscience (2010) 1.04
Dopaminergic signaling mediates the motivational response underlying the opponent process to chronic but not acute nicotine. Neuropsychopharmacology (2009) 1.03
Translational behaviour-genetic studies of alcohol: are we there yet? Genes Brain Behav (2012) 1.02
A combination of buprenorphine and naltrexone blocks compulsive cocaine intake in rodents without producing dependence. Sci Transl Med (2012) 1.01
Serotonergic mechanisms in addiction-related memories. Behav Brain Res (2008) 1.01
Context-induced relapse to alcohol seeking after punishment in a rat model. Biol Psychiatry (2012) 1.01
Traumatic stress reactivity promotes excessive alcohol drinking and alters the balance of prefrontal cortex-amygdala activity. Transl Psychiatry (2013) 1.00
Plasticity of reward neurocircuitry and the 'dark side' of drug addiction. Nat Neurosci (2005) 4.36
Adult neurogenesis: from precursors to network and physiology. Physiol Rev (2005) 4.25
Review. Neurobiological mechanisms for opponent motivational processes in addiction. Philos Trans R Soc Lond B Biol Sci (2008) 2.97
Spatial memory performances of aged rats in the water maze predict levels of hippocampal neurogenesis. Proc Natl Acad Sci U S A (2003) 2.83
Evidence for enhanced neurobehavioral vulnerability to nicotine during periadolescence in rats. J Neurosci (2003) 1.61
The glucocorticoid receptor as a potential target to reduce cocaine abuse. J Neurosci (2003) 1.34
Nicotine self-administration impairs hippocampal plasticity. J Neurosci (2002) 1.23
Postnatal stimulation of the pups counteracts prenatal stress-induced deficits in hippocampal neurogenesis. Biol Psychiatry (2006) 1.12
Methylazoxymethanol acetate does not fully block cell genesis in the young and aged dentate gyrus. Eur J Neurosci (2005) 1.12
Preexposure during or following adolescence differently affects nicotine-rewarding properties in adult rats. Psychopharmacology (Berl) (2005) 1.09
Influence of cue-conditioning on acquisition, maintenance and relapse of cocaine intravenous self-administration. Eur J Neurosci (2002) 1.08
Allostasis and addiction: role of the dopamine and corticotropin-releasing factor systems. Physiol Behav (2011) 1.07
Glucocorticoid negative feedback in methadone-maintained former heroin addicts with ongoing cocaine dependence: dose-response to dexamethasone suppression. Addict Biol (2006) 0.92
The neurosteroid allopregnanolone increases dopamine release and dopaminergic response to morphine in the rat nucleus accumbens. Eur J Neurosci (2002) 0.92
Individual vulnerability to addiction. Ann N Y Acad Sci (2011) 0.91
Anti-S-nitrosocysteine antibodies are a predictive marker for demyelination in experimental autoimmune encephalomyelitis: implications for multiple sclerosis. J Neurosci (2002) 0.87
Age-dependent effect of prenatal stress on hippocampal cell proliferation in female rats. Eur J Neurosci (2009) 0.84
Early and later adoptions differently modify mother-pup interactions. Behav Neurosci (2004) 0.84
Individual differences in the effects of chronic prazosin hydrochloride treatment on hippocampal mineralocorticoid and glucocorticoid receptors. Eur J Neurosci (2007) 0.83
Alcoholism, corticotropin-releasing factor, and molecular genetic allostasis. Biol Psychiatry (2008) 0.81
The neurosteroid pregnenolone sulfate infused into the medial septum nucleus increases hippocampal acetylcholine and spatial memory in rats. Brain Res (2002) 0.80
Individual differences in cognitive aging: implication of pregnenolone sulfate. Prog Neurobiol (2003) 0.80
Low brain allopregnanolone levels mediate flattened circadian activity associated with memory impairments in aged rats. Biol Psychiatry (2010) 0.79
Individual vulnerability to substance abuse and affective disorders: role of early environmental influences. Neurotox Res (2002) 0.79
Neurosteroids and cholinergic systems: implications for sleep and cognitive processes and potential role of age-related changes. Psychopharmacology (Berl) (2006) 0.79
Flaws of drug instrumentalization. Behav Brain Sci (2011) 0.78
Sleep-wake states and cortical synchronization control by pregnenolone sulfate into the pedunculopontine nucleus. J Neurosci Res (2004) 0.77
Neuroactive steroids: new biomarkers of cognitive aging. J Steroid Biochem Mol Biol (2003) 0.76
Paradoxical effect of severe dietary restriction on Long-Evans rat life span. Int J Vitam Nutr Res (2010) 0.76
[Overview of acute and chronic stress responses]. Med Sci (Paris) (2012) 0.75