Published in Theor Biol Med Model on November 12, 2008
Should DSM-V Designate "Internet Addiction" a Mental Disorder? Psychiatry (Edgmont) (2009) 2.12
Repetitive transcranial magnetic stimulation of the dorsolateral prefrontal cortex reduces nicotine cue craving. Biol Psychiatry (2013) 1.63
Roux-en-Y gastric bypass surgery changes food reward in rats. Int J Obes (Lond) (2010) 1.41
"Liking" and "wanting" of sweet and oily food stimuli as affected by high-fat diet-induced obesity, weight loss, leptin, and genetic predisposition. Am J Physiol Regul Integr Comp Physiol (2011) 1.13
Pain and suicidality: insights from reward and addiction neuroscience. Prog Neurobiol (2013) 1.08
rsfMRI effects of KB220Z™ on neural pathways in reward circuitry of abstinent genotyped heroin addicts. Postgrad Med (2014) 1.04
Neurogenetic Impairments of Brain Reward Circuitry Links to Reward Deficiency Syndrome (RDS): Potential Nutrigenomic Induced Dopaminergic Activation. J Genet Syndr Gene Ther (2012) 0.91
Neurogenetics of dopaminergic receptor supersensitivity in activation of brain reward circuitry and relapse: proposing "deprivation-amplification relapse therapy" (DART). Postgrad Med (2009) 0.90
Neuro-psychopharmacogenetics and Neurological Antecedents of Posttraumatic Stress Disorder: Unlocking the Mysteries of Resilience and Vulnerability. Curr Neuropharmacol (2010) 0.89
Neuropsychopharmacology and neurogenetic aspects of executive functioning: should reward gene polymorphisms constitute a diagnostic tool to identify individuals at risk for impaired judgment? Mol Neurobiol (2012) 0.88
Low dopamine function in attention deficit/hyperactivity disorder: should genotyping signify early diagnosis in children? Postgrad Med (2014) 0.88
The association between the SLC6A3 VNTR 9-repeat allele and alcoholism-a meta-analysis. Alcohol Clin Exp Res (2011) 0.87
Buprenorphine Response as a Function of Neurogenetic Polymorphic Antecedents: Can Dopamine Genes Affect Clinical Outcomes in Reward Deficiency Syndrome (RDS)? J Addict Res Ther (2015) 0.85
Dopamine Genetics and Function in Food and Substance Abuse. J Genet Syndr Gene Ther (2013) 0.84
The interaction of reward genes with environmental factors in contribution to alcoholism in mexican americans. Alcohol Clin Exp Res (2009) 0.83
The Molecular Neurobiology of Twelve Steps Program & Fellowship: Connecting the Dots for Recovery. J Reward Defic Syndr (2015) 0.81
Epigenetics in Developmental Disorder: ADHD and Endophenotypes. J Genet Syndr Gene Ther (2011) 0.81
Quantitative Electroencephalography Analysis (qEEG) of Neuro-Electro-Adaptive Therapy 12™ [NEAT12] Up-Regulates Cortical Potentials in an Alcoholic during Protracted Abstinence: Putative Anti-Craving Implications. J Addict Res Ther (2015) 0.81
Reward-based hypertension control by a synthetic brain-dopamine interface. Proc Natl Acad Sci U S A (2013) 0.80
Translational strategies for therapeutic development in nicotine addiction: rethinking the conventional bench to bedside approach. Prog Neuropsychopharmacol Biol Psychiatry (2013) 0.79
Neuropsychiatric Genetics of Happiness, Friendships, and Politics: Hypothesizing Homophily ("Birds of a Feather Flock Together") as a Function of Reward Gene Polymorphisms. J Genet Syndr Gene Ther (2012) 0.78
Rhodiola rosea Impairs Acquisition and Expression of Conditioned Place Preference Induced by Cocaine. Evid Based Complement Alternat Med (2013) 0.78
Early intervention of intravenous KB220IV--neuroadaptagen amino-acid therapy (NAAT) improves behavioral outcomes in a residential addiction treatment program: a pilot study. J Psychoactive Drugs (2013) 0.76
Pharmacotherapies for Overeating and Obesity. J Genet Syndr Gene Ther (2013) 0.76
Enhancing Brain Pregnenolone May Protect Cannabis Intoxication but Should Not Be Considered as an Anti-addiction Therapeutic: Hypothesizing Dopaminergic Blockade and Promoting Anti-Reward. J Reward Defic Syndr (2015) 0.76
Involvement of dopamine D2 receptors in addictive-like behaviour for acetaldehyde. PLoS One (2014) 0.76
Both nicotine reward and withdrawal are enhanced in a rodent model of diabetes. Psychopharmacology (Berl) (2017) 0.75
Fifty Years in the Development of a Glutaminergic-Dopaminergic Optimization Complex (KB220) to Balance Brain Reward Circuitry in Reward Deficiency Syndrome: A Pictorial. Austin Addict Sci (2016) 0.75
Hypothesizing that, A Pro-Dopamine Regulator (KB220Z) Should Optimize, but Not Hyper-Activate the Activity of Trace Amine-Associated Receptor 1 (TAAR-1) and Induce Anti-Craving of Psychostimulants in the Long-Term. J Reward Defic Syndr Addict Sci (2016) 0.75
THE BENEFITS OF CUSTOMIZED DNA DIRECTED NUTRITION TO BALANCE THE BRAIN REWARD CIRCUITRY AND REDUCE ADDICTIVE BEHAVIORS. Precis Med (Bangalore) (2016) 0.75
Pro-Dopamine Regulator - (KB220) to Balance Brain Reward Circuitry in Reward Deficiency Syndrome (RDS). J Reward Defic Syndr Addict Sci (2017) 0.75
"Pro-dopamine regulation (KB220Z™)" as a long-term therapeutic modality to overcome reduced resting state dopamine tone in opiate/opioid epidemic in America. J Syst Integr Neurosci (2016) 0.75
Genetic and environmental factors in relative body weight and human adiposity. Behav Genet (1997) 12.07
The debate over dopamine's role in reward: the case for incentive salience. Psychopharmacology (Berl) (2006) 9.18
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Food reinforcement, the dopamine D2 receptor genotype, and energy intake in obese and nonobese humans. Behav Neurosci (2007) 2.38
Profound decreases in dopamine release in striatum in detoxified alcoholics: possible orbitofrontal involvement. J Neurosci (2007) 2.38
Immediate reward bias in humans: fronto-parietal networks and a role for the catechol-O-methyltransferase 158(Val/Val) genotype. J Neurosci (2007) 2.33
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Association of specific haplotypes of D2 dopamine receptor gene with vulnerability to heroin dependence in 2 distinct populations. Arch Gen Psychiatry (2004) 2.12
Opiate-like effects of sugar on gene expression in reward areas of the rat brain. Brain Res Mol Brain Res (2004) 2.00
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Cannabinoid CB1 receptor antagonists as promising new medications for drug dependence. J Pharmacol Exp Ther (2004) 1.83
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Behavioral functions of the mesolimbic dopaminergic system: an affective neuroethological perspective. Brain Res Rev (2007) 1.50
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Effects of ethanol on midbrain neurons: role of opioid receptors. Alcohol Clin Exp Res (2007) 1.21
Imaging gene-substance interactions: the effect of the DRD2 TaqIA polymorphism and the dopamine agonist bromocriptine on the brain activation during the anticipation of reward. Neurosci Lett (2006) 1.20
Addiction in Parkinson's disease: impact of subthalamic nucleus deep brain stimulation. Mov Disord (2005) 1.18
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Attention-deficit-hyperactivity disorder and reward deficiency syndrome. Neuropsychiatr Dis Treat (2008) 1.14
Dual dopamine/serotonin releasers as potential medications for stimulant and alcohol addictions. AAPS J (2007) 1.06
Association between the DRD2 A1 allele and opium addiction in the Iranian population. Am J Med Genet B Neuropsychiatr Genet (2005) 1.06
The dopamine D2 receptor (DRD2) as a major gene in obesity and height. Biochem Med Metab Biol (1993) 1.02
A prospective study of alcoholism and the risk of Parkinson's disease. J Neurol (2004) 0.98
Dopamine genes and pathological gambling in discordant sib-pairs. J Gambl Stud (2007) 0.97
Genotrim, a DNA-customized nutrigenomic product, targets genetic factors of obesity: hypothesizing a dopamine-glucose correlation demonstrating reward deficiency syndrome (RDS). Med Hypotheses (2006) 0.95
Genomics and the future of pharmacotherapy in psychiatry. Int Rev Psychiatry (2007) 0.95
Obesity, attention deficit-hyperactivity disorder and the dopaminergic reward system. Coll Antropol (2007) 0.95
Reward deficiency syndrome in obesity: a preliminary cross-sectional trial with a Genotrim variant. Adv Ther (2007) 0.95
Differential coupling of rat D2 dopamine receptor isoforms expressed in Spodoptera frugiperda insect cells. J Pharmacol Exp Ther (1996) 0.93
LG839: anti-obesity effects and polymorphic gene correlates of reward deficiency syndrome. Adv Ther (2008) 0.93
Joint effect of dopaminergic genes on likelihood of smoking following treatment with bupropion SR. Health Psychol (2007) 0.93
The efficacy of acamprosate and naltrexone in the treatment of alcohol dependence: a relative benefits analysis of randomized controlled trials. Am J Drug Alcohol Abuse (2008) 0.91
DRD2/ANKK1 TaqI polymorphism and smoking behavior of Egyptian male cigarette smokers. Nicotine Tob Res (2007) 0.90
Naloxone-induced inhibition of ethanol dependence in mice. Nature (1977) 0.90
The role of the endogenous cannabinoid system in drug addiction. Drug News Perspect (2008) 0.90
The A1 allele of the DRD2 gene (TaqI A polymorphisms) is associated with antisocial personality in a sample of alcohol-dependent patients. Eur Psychiatry (2003) 0.90
Manipulation of catechol-O-methyl-transferase (COMT) activity to influence the attenuation of substance seeking behavior, a subtype of Reward Deficiency Syndrome (RDS), is dependent upon gene polymorphisms: a hypothesis. Med Hypotheses (2007) 0.88
Agonists and antagonists differentially regulate the high affinity state of the D2L receptor in human embryonic kidney 293 cells. Mol Pharmacol (1995) 0.87
Narcotic antagonists in drug dependence: pilot study showing enhancement of compliance with SYN-10, amino-acid precursors and enkephalinase inhibition therapy. Med Hypotheses (2004) 0.87
Genetic loading on human loving styles. Neuro Endocrinol Lett (2007) 0.86
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Effects of gabapentin on cocaine self-administration, cocaine-triggered relapse and cocaine-enhanced nucleus accumbens dopamine in rats. Drug Alcohol Depend (2007) 0.83
Gene \Narcotic Attenuation Program attenuates substance use disorder, a clinical subtype of reward deficiency syndrome. Adv Ther (2007) 0.83
Does dopaminergic reward system contribute to explaining comorbidity obesity and ADHD? Med Hypotheses (2007) 0.82
Enhancement of attention processing by Kantroll in healthy humans: a pilot study. Clin Electroencephalogr (1997) 0.81
Genotype combinations for monoamine oxidase-B intron 13 polymorphism and dopamine D2 receptor TaqIB polymorphism are associated with ever-smoking status among men. Neurosci Lett (2005) 0.80
Neurogenetic interactions and aberrant behavioral co-morbidity of attention deficit hyperactivity disorder (ADHD): dispelling myths. Theor Biol Med Model (2005) 0.80
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Neurogenetic deficits caused by alcoholism: restoration by SAAVE, a neuronutrient intervention adjunct. J Psychoactive Drugs (1989) 0.79
[Hypothesis: Parkinson's disease, reward deficiency syndrome and addictive effects of levodopa]. Neurologia (2004) 0.77
MPP(+) and glutamate in the degeneration of nigral dopaminergic neurons. Parkinsonism Relat Disord (1999) 0.77
Cytotoxicity and oxidative mechanisms of different forms of chromium. Toxicology (2002) 2.32
Decreased volume of the brain reward system in alcoholism. Biol Psychiatry (2008) 2.15
Phosphorylation of Akt (Ser473) is an excellent predictor of poor clinical outcome in prostate cancer. Cancer Res (2004) 2.15
Measuring adiposity in patients: the utility of body mass index (BMI), percent body fat, and leptin. PLoS One (2012) 2.12
Determining risk of biochemical recurrence in prostate cancer by immunohistochemical detection of PTEN expression and Akt activation. Clin Cancer Res (2007) 1.66
Enzyme genomics: Application of general enzymatic screens to discover new enzymes. FEMS Microbiol Rev (2005) 1.61
Are dopaminergic genes involved in a predisposition to pathological aggression? Hypothesizing the importance of "super normal controls" in psychiatricgenetic research of complex behavioral disorders. Med Hypotheses (2005) 1.58
Relationship between dopaminergic neurotransmission, alcoholism, and Reward Deficiency syndrome. Am J Med Genet B Neuropsychiatr Genet (2005) 1.52
Effects of tuberculosis, race, and human gene SLCO1B1 polymorphisms on rifampin concentrations. Antimicrob Agents Chemother (2010) 1.45
Signal transduction pathways in androgen-dependent and -independent prostate cancer cell proliferation. Endocr Relat Cancer (2005) 1.43
Osteoblastoma of the maxilla and mandible: a report of 24 cases, review of the literature, and discussion of its relationship to osteoid osteoma of the jaws. Oral Surg Oral Med Oral Pathol Oral Radiol Endod (2006) 1.41
Frontal white matter and cingulum diffusion tensor imaging deficits in alcoholism. Alcohol Clin Exp Res (2008) 1.38
Diabetic eNOS knockout mice develop distinct macro- and microvascular complications. Lab Invest (2008) 1.32
"Liking" and "wanting" linked to Reward Deficiency Syndrome (RDS): hypothesizing differential responsivity in brain reward circuitry. Curr Pharm Des (2012) 1.31
Evaluation of napsin A, cytokeratin 5/6, p63, and thyroid transcription factor 1 in adenocarcinoma versus squamous cell carcinoma of the lung. Arch Pathol Lab Med (2012) 1.30
Sexually dimorphic effect of the Val66Met polymorphism of BDNF on susceptibility to Alzheimer's disease: New data and meta-analysis. Am J Med Genet B Neuropsychiatr Genet (2010) 1.20
A randomized single-blind pilot study of compensatory strategies in schizophrenia outpatients. Schizophr Bull (2002) 1.20
Nuclear versus cytoplasmic localization of filamin A in prostate cancer: immunohistochemical correlation with metastases. Clin Cancer Res (2009) 1.20
Neurogenetics and Nutrigenomics of Neuro-Nutrient Therapy for Reward Deficiency Syndrome (RDS): Clinical Ramifications as a Function of Molecular Neurobiological Mechanisms. J Addict Res Ther (2012) 1.19
Induction of adaptive response in human blood lymphocytes exposed to radiofrequency radiation. Radiat Res (2009) 1.18
The addictive brain: all roads lead to dopamine. J Psychoactive Drugs (2012) 1.16
Alcoholism and dampened temporal limbic activation to emotional faces. Alcohol Clin Exp Res (2009) 1.14
Attention-deficit-hyperactivity disorder and reward deficiency syndrome. Neuropsychiatr Dis Treat (2008) 1.14
Evaluation of time to detection of Mycobacterium tuberculosis in broth culture as a determinant for end points in treatment trials. J Clin Microbiol (2010) 1.11
Overcoming qEEG abnormalities and reward gene deficits during protracted abstinence in male psychostimulant and polydrug abusers utilizing putative dopamine D₂ agonist therapy: part 2. Postgrad Med (2010) 1.09
How the relationship of attitudes toward mental health treatment and service use differs by age, gender, ethnicity/race and education. Soc Psychiatry Psychiatr Epidemiol (2009) 1.07
Sex, drugs, and rock 'n' roll: hypothesizing common mesolimbic activation as a function of reward gene polymorphisms. J Psychoactive Drugs (2012) 1.06
rsfMRI effects of KB220Z™ on neural pathways in reward circuitry of abstinent genotyped heroin addicts. Postgrad Med (2014) 1.04
Positive margins following surgical resection of breast carcinoma: analysis of pathologic correlates. J Surg Oncol (2004) 1.02
Generational association studies of dopaminergic genes in reward deficiency syndrome (RDS) subjects: selecting appropriate phenotypes for reward dependence behaviors. Int J Environ Res Public Health (2011) 1.01
Neurogenetics and clinical evidence for the putative activation of the brain reward circuitry by a neuroadaptagen: proposing an addiction candidate gene panel map. J Psychoactive Drugs (2011) 0.99
Chemoradionuclide therapy with 186Re-labeled liposomal doxorubicin in combination with radiofrequency ablation for effective treatment of head and neck cancer in a nude rat tumor xenograft model. Radiology (2011) 0.98
Induction of adaptive response in human blood lymphocytes exposed to 900 MHz radiofrequency fields: influence of cell cycle. Int J Radiat Biol (2011) 0.98
Alcoholism and judgments of affective stimuli. Neuropsychology (2007) 0.98
Genetic Addiction Risk Score (GARS): molecular neurogenetic evidence for predisposition to Reward Deficiency Syndrome (RDS). Mol Neurobiol (2014) 0.96
Genotrim, a DNA-customized nutrigenomic product, targets genetic factors of obesity: hypothesizing a dopamine-glucose correlation demonstrating reward deficiency syndrome (RDS). Med Hypotheses (2006) 0.95
Reward deficiency syndrome in obesity: a preliminary cross-sectional trial with a Genotrim variant. Adv Ther (2007) 0.95
The effectiveness of quetiapine versus conventional antipsychotics in improving cognitive and functional outcomes in standard treatment settings. J Clin Psychiatry (2003) 0.94
LG839: anti-obesity effects and polymorphic gene correlates of reward deficiency syndrome. Adv Ther (2008) 0.93
RANTES: a genetic risk marker for multiple sclerosis. Mult Scler (2004) 0.92
Delayed P300 latency correlates with abnormal Test of Variables of Attention (TOVA) in adults and predicts early cognitive decline in a clinical setting. Adv Ther (2006) 0.92
Patterns of prefrontal dysfunction in alcoholics with and without Korsakoff's syndrome, patients with Parkinson's disease, and patients with rupture and repair of the anterior communicating artery. Neuropsychiatr Dis Treat (2006) 0.91
Diabetes and risk of renal cell carcinoma. J Cancer (2011) 0.91
Drinking history associations with regional white matter volumes in alcoholic men and women. Alcohol Clin Exp Res (2012) 0.91
Risk factors for the development of hypothyroidism after hemithyroidectomy. Arch Otolaryngol Head Neck Surg (2006) 0.91
Variants of the orexin2/hcrt2 receptor gene identified in patients with excessive daytime sleepiness and patients with Tourette's syndrome comorbidity. Am J Med Genet B Neuropsychiatr Genet (2004) 0.91
Neurogenetics of dopaminergic receptor supersensitivity in activation of brain reward circuitry and relapse: proposing "deprivation-amplification relapse therapy" (DART). Postgrad Med (2009) 0.90
Combination radiofrequency ablation and intravenous radiolabeled liposomal Doxorubicin: imaging and quantification of increased drug delivery to tumors. Radiology (2010) 0.90
Development of the Bipolar Inventory of Symptoms Scale: concurrent validity, discriminant validity and retest reliability. Int J Methods Psychiatr Res (2008) 0.89
Neuro-psychopharmacogenetics and Neurological Antecedents of Posttraumatic Stress Disorder: Unlocking the Mysteries of Resilience and Vulnerability. Curr Neuropharmacol (2010) 0.89
Hypothesizing that brain reward circuitry genes are genetic antecedents of pain sensitivity and critical diagnostic and pharmacogenomic treatment targets for chronic pain conditions. Med Hypotheses (2008) 0.89