PubRank

Hermann-Josef Gröne

Author PubWeight™ 203.61‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Netting neutrophils in autoimmune small-vessel vasculitis. Nat Med 2009 6.72
2 The matrix component biglycan is proinflammatory and signals through Toll-like receptors 4 and 2 in macrophages. J Clin Invest 2005 3.99
3 Vascular normalization in Rgs5-deficient tumours promotes immune destruction. Nature 2008 3.05
4 Definition of estrogen receptor pathway critical for estrogen positive feedback to gonadotropin-releasing hormone neurons and fertility. Neuron 2006 3.04
5 Modular activation of nuclear factor-kappaB transcriptional programs in human diabetic nephropathy. Diabetes 2006 2.85
6 Genetic inactivation of the transcription factor TIF-IA leads to nucleolar disruption, cell cycle arrest, and p53-mediated apoptosis. Mol Cell 2005 2.46
7 Invariant NKT cells reduce the immunosuppressive activity of influenza A virus-induced myeloid-derived suppressor cells in mice and humans. J Clin Invest 2008 2.46
8 Group testing for pathway analysis improves comparability of different microarray datasets. Bioinformatics 2006 2.37
9 Inhibition of platelet-derived growth factor signaling attenuates pulmonary fibrosis. J Exp Med 2005 2.25
10 Normal development and function of invariant natural killer T cells in mice with isoglobotrihexosylceramide (iGb3) deficiency. Proc Natl Acad Sci U S A 2007 2.24
11 TLR4 links podocytes with the innate immune system to mediate glomerular injury. J Am Soc Nephrol 2008 2.23
12 Yes and PI3K bind CD95 to signal invasion of glioblastoma. Cancer Cell 2008 2.21
13 Biglycan, a danger signal that activates the NLRP3 inflammasome via toll-like and P2X receptors. J Biol Chem 2009 2.12
14 An efficient and versatile system for acute and chronic modulation of renal tubular function in transgenic mice. Nat Med 2008 2.12
15 Kidney dendritic cell activation is required for progression of renal disease in a mouse model of glomerular injury. J Clin Invest 2009 2.01
16 Focal segmental glomerulosclerosis is induced by microRNA-193a and its downregulation of WT1. Nat Med 2013 1.98
17 Decrease and gain of gene expression are equally discriminatory markers for prostate carcinoma: a gene expression analysis on total and microdissected prostate tissue. Am J Pathol 2002 1.96
18 Endostatin's antiangiogenic signaling network. Mol Cell 2004 1.95
19 Tubular overexpression of transforming growth factor-beta1 induces autophagy and fibrosis but not mesenchymal transition of renal epithelial cells. Am J Pathol 2010 1.93
20 AHI1 is required for photoreceptor outer segment development and is a modifier for retinal degeneration in nephronophthisis. Nat Genet 2010 1.89
21 E6 and E7 from beta HPV38 cooperate with ultraviolet light in the development of actinic keratosis-like lesions and squamous cell carcinoma in mice. PLoS Pathog 2011 1.89
22 Parietal epithelial cells participate in the formation of sclerotic lesions in focal segmental glomerulosclerosis. J Am Soc Nephrol 2011 1.80
23 Prediction of acute renal allograft rejection by urinary monokine induced by IFN-gamma (MIG). J Am Soc Nephrol 2005 1.72
24 Gene expression fingerprints in human tubulointerstitial inflammation and fibrosis as prognostic markers of disease progression. Kidney Int 2004 1.72
25 A chemokine receptor CCR-1 antagonist reduces renal fibrosis after unilateral ureter ligation. J Clin Invest 2002 1.70
26 Viral double-stranded RNA aggravates lupus nephritis through Toll-like receptor 3 on glomerular mesangial cells and antigen-presenting cells. J Am Soc Nephrol 2005 1.69
27 Lineage specification of parietal epithelial cells requires β-catenin/Wnt signaling. J Am Soc Nephrol 2011 1.64
28 Inhibition of alpha(v)beta3 integrin survival signaling enhances antiangiogenic and antitumor effects of radiotherapy. Clin Cancer Res 2005 1.64
29 Trimodal cancer treatment: beneficial effects of combined antiangiogenesis, radiation, and chemotherapy. Cancer Res 2005 1.62
30 Activation of toll-like receptor-9 induces progression of renal disease in MRL-Fas(lpr) mice. FASEB J 2004 1.60
31 Gnotobiotic piglets develop thrombotic microangiopathy after oral infection with enterohemorrhagic Escherichia coli. Am J Clin Pathol 2002 1.59
32 Hfe acts in hepatocytes to prevent hemochromatosis. Cell Metab 2008 1.55
33 Gene expression profiles of podocyte-associated molecules as diagnostic markers in acquired proteinuric diseases. J Am Soc Nephrol 2003 1.54
34 Iron regulatory proteins are essential for intestinal function and control key iron absorption molecules in the duodenum. Cell Metab 2008 1.54
35 Absence of decorin adversely influences tubulointerstitial fibrosis of the obstructed kidney by enhanced apoptosis and increased inflammatory reaction. Am J Pathol 2002 1.52
36 Impairment of sodium balance in mice deficient in renal principal cell mineralocorticoid receptor. J Am Soc Nephrol 2007 1.51
37 cDNA microarray analysis reveals new candidate genes possibly linked to side effects under mycophenolate mofetil therapy. Transplantation 2004 1.48
38 Neuronal expression of glucosylceramide synthase in central nervous system regulates body weight and energy homeostasis. PLoS Biol 2013 1.48
39 Cell-specific deletion of glucosylceramide synthase in brain leads to severe neural defects after birth. Proc Natl Acad Sci U S A 2005 1.44
40 Renal fibrosis is attenuated by targeted disruption of KCa3.1 potassium channels. Proc Natl Acad Sci U S A 2009 1.44
41 Comparative promoter analysis allows de novo identification of specialized cell junction-associated proteins. Proc Natl Acad Sci U S A 2006 1.43
42 Chemokine receptor CCR1 but not CCR5 mediates leukocyte recruitment and subsequent renal fibrosis after unilateral ureteral obstruction. J Am Soc Nephrol 2004 1.41
43 Cardiac hypertrophy and fibrosis in chronic L-NAME-treated AT2 receptor-deficient mice. J Hypertens 2004 1.39
44 Temporal Cre-mediated recombination exclusively in endothelial cells using Tie2 regulatory elements. Genesis 2002 1.38
45 Effects of increased renal tubular vascular endothelial growth factor (VEGF) on fibrosis, cyst formation, and glomerular disease. Am J Pathol 2009 1.37
46 High-accuracy amplification of nanogram total RNA amounts for gene profiling. Genomics 2004 1.35
47 G-rich DNA suppresses systemic lupus. J Am Soc Nephrol 2005 1.35
48 Novel role of toll-like receptor 3 in hepatitis C-associated glomerulonephritis. Am J Pathol 2006 1.28
49 Human nephrosclerosis triggers a hypoxia-related glomerulopathy. Am J Pathol 2009 1.27
50 Improved elucidation of biological processes linked to diabetic nephropathy by single probe-based microarray data analysis. PLoS One 2008 1.27
51 Integrity and barrier function of the epidermis critically depend on glucosylceramide synthesis. J Biol Chem 2006 1.27
52 Loss of ceramide synthase 3 causes lethal skin barrier disruption. Hum Mol Genet 2011 1.26
53 Bacterial CpG-DNA aggravates immune complex glomerulonephritis: role of TLR9-mediated expression of chemokines and chemokine receptors. J Am Soc Nephrol 2003 1.25
54 CCR1 blockade reduces interstitial inflammation and fibrosis in mice with glomerulosclerosis and nephrotic syndrome. Kidney Int 2004 1.24
55 Reduction of circulating soluble Flt-1 alleviates preeclampsia-like symptoms in a mouse model. J Cell Mol Med 2009 1.24
56 Direct acute tubular damage contributes to Shigatoxin-mediated kidney failure. J Pathol 2014 1.22
57 Roles of SLC/CCL21 and CCR7 in human kidney for mesangial proliferation, migration, apoptosis, and tissue homeostasis. J Immunol 2002 1.21
58 Decorin-mediated regulation of fibrillin-1 in the kidney involves the insulin-like growth factor-I receptor and Mammalian target of rapamycin. Am J Pathol 2007 1.20
59 LY2109761 attenuates radiation-induced pulmonary murine fibrosis via reversal of TGF-β and BMP-associated proinflammatory and proangiogenic signals. Clin Cancer Res 2012 1.20
60 Male germ cells require polyenoic sphingolipids with complex glycosylation for completion of meiosis: a link to ceramide synthase-3. J Biol Chem 2008 1.18
61 13-cis retinoic acid inhibits development and progression of chronic allograft nephropathy. Am J Pathol 2005 1.17
62 Laser microdissection and gene expression analysis on formaldehyde-fixed archival tissue. Kidney Int 2002 1.17
63 Cytoprotective signaling by activated protein C requires protease-activated receptor-3 in podocytes. Blood 2011 1.17
64 T cell activation is driven by an ADP-dependent glucokinase linking enhanced glycolysis with mitochondrial reactive oxygen species generation. Cell Rep 2012 1.16
65 Novel class of glycosphingolipids involved in male fertility. J Biol Chem 2005 1.16
66 Iron regulatory proteins secure mitochondrial iron sufficiency and function. Cell Metab 2010 1.14
67 Deficiency of liver sinusoidal scavenger receptors stabilin-1 and -2 in mice causes glomerulofibrotic nephropathy via impaired hepatic clearance of noxious blood factors. J Clin Invest 2011 1.14
68 Recipient Toll-like receptors contribute to chronic graft dysfunction by both MyD88- and TRIF-dependent signaling. Dis Model Mech 2009 1.11
69 The Gq/G11-mediated signaling pathway is critical for autocrine potentiation of insulin secretion in mice. J Clin Invest 2010 1.10
70 Bacterial lipopeptide triggers massive albuminuria in murine lupus nephritis by activating Toll-like receptor 2 at the glomerular filtration barrier. Immunology 2008 1.09
71 Clinical and mechanistic aspects of glucocorticoid-induced chemotherapy resistance in the majority of solid tumors. Cancer Biol Ther 2007 1.07
72 Iron homeostasis in the brain: complete iron regulatory protein 2 deficiency without symptomatic neurodegeneration in the mouse. Nat Genet 2006 1.07
73 Successful prenatal mannose treatment for congenital disorder of glycosylation-Ia in mice. Nat Med 2011 1.06
74 Cre recombinase-mediated gene targeting of mesenchymal cells. Genesis 2004 1.05
75 A novel human high-risk ependymoma stem cell model reveals the differentiation-inducing potential of the histone deacetylase inhibitor Vorinostat. Acta Neuropathol 2011 1.04
76 Golgi GDP-fucose transporter-deficient mice mimic congenital disorder of glycosylation IIc/leukocyte adhesion deficiency II. J Biol Chem 2007 1.03
77 Immunodetection and quantification of vascular endothelial growth factor receptor-3 in human malignant tumor tissues. Int J Cancer 2004 1.03
78 CC chemokine ligand 5/RANTES chemokine antagonists aggravate glomerulonephritis despite reduction of glomerular leukocyte infiltration. J Immunol 2003 1.03
79 Late treatment with imatinib mesylate ameliorates radiation-induced lung fibrosis in a mouse model. Radiat Oncol 2009 1.03
80 Regulation of fibrillin-1 by biglycan and decorin is important for tissue preservation in the kidney during pressure-induced injury. Am J Pathol 2004 1.03
81 Nephrotic-range proteinuria following pamidronate therapy in a patient with metastatic breast cancer: mitochondrial toxicity as a pathogenetic concept? Am J Kidney Dis 2006 1.03
82 Histone deacetylase 10 promotes autophagy-mediated cell survival. Proc Natl Acad Sci U S A 2013 1.01
83 p38 MAPK controls prothrombin expression by regulated RNA 3' end processing. Mol Cell 2011 1.01
84 Endogenous and exogenous pentraxin-3 limits postischemic acute and chronic kidney injury. Kidney Int 2013 1.00
85 Rescue of lethal molybdenum cofactor deficiency by a biosynthetic precursor from Escherichia coli. Hum Mol Genet 2004 1.00
86 Hyporesponsiveness to glucocorticoids in mice genetically deficient for the corticosteroid binding globulin. Mol Cell Biol 2006 1.00
87 Dkk1 and noggin cooperate in mammalian head induction. Genes Dev 2003 1.00
88 Wnt-signaling pathways in progressive renal fibrosis. Expert Opin Ther Targets 2011 0.99
89 Disturbed epidermal structure in mice with temporally controlled fatp4 deficiency. J Invest Dermatol 2005 0.99
90 Characterization of CXCL16 and ADAM10 in the normal and transplanted kidney. Kidney Int 2008 0.97
91 CXCR3 is involved in tubulointerstitial injury in human glomerulonephritis. Am J Pathol 2004 0.97
92 Globosides but not isoglobosides can impact the development of invariant NKT cells and their interaction with dendritic cells. J Immunol 2012 0.96
93 Isotretinoin ameliorates renal damage in experimental acute renal allograft rejection. Transplantation 2003 0.96
94 E7 oncoprotein of novel human papillomavirus type 108 lacking the E6 gene induces dysplasia in organotypic keratinocyte cultures. J Virol 2009 0.96
95 Repuncturing the renal biopsy: strategies for molecular diagnosis in nephrology. J Am Soc Nephrol 2002 0.95
96 Peroxisome proliferator-activated receptor (PPAR)gamma can inhibit chronic renal allograft damage. Am J Pathol 2010 0.95
97 Iron overload in adult Hfe-deficient mice independent of changes in the steady-state expression of the duodenal iron transporters DMT1 and Ireg1/ferroportin. J Mol Med (Berl) 2003 0.95
98 Imaging of complex sulfatides SM3 and SB1a in mouse kidney using MALDI-TOF/TOF mass spectrometry. Anal Bioanal Chem 2011 0.95
99 Drug-induced granulomatous interstitial nephritis in a patient with ankylosing spondylitis during therapy with adalimumab. Am J Kidney Dis 2010 0.95
100 Sulfatides are required for renal adaptation to chronic metabolic acidosis. Proc Natl Acad Sci U S A 2013 0.94
101 Pulmonary hypertension and right heart failure in pituitary adenylate cyclase-activating polypeptide type I receptor-deficient mice. Circulation 2004 0.93
102 Sulfated glycosphingolipid as mediator of phagocytosis: SM4s enhances apoptotic cell clearance and modulates macrophage activity. J Immunol 2007 0.93
103 Iron regulatory proteins control a mucosal block to intestinal iron absorption. Cell Rep 2013 0.93
104 Identification of protein targets for mycophenolic acid acyl glucuronide in rat liver and colon tissue. Proteomics 2004 0.93
105 Vascular endothelial growth factor in diabetic nephropathy. Kidney Blood Press Res 2003 0.93
106 Hantaan virus infection causes an acute neurological disease that is fatal in adult laboratory mice. J Virol 2002 0.92
107 The proteoglycan biglycan enhances antigen-specific T cell activation potentially via MyD88 and TRIF pathways and triggers autoimmune perimyocarditis. J Immunol 2011 0.92
108 Lack of centrioles and primary cilia in STIL(-/-) mouse embryos. Cell Cycle 2014 0.91
109 Cell biological and biochemical characterization of drebrin complexes in mesangial cells and podocytes of renal glomeruli. J Am Soc Nephrol 2003 0.91
110 Expression of a novel PDGF isoform, PDGF-C, in normal and diseased rat kidney. J Am Soc Nephrol 2002 0.90
111 PDGF-C expression in the developing and normal adult human kidney and in glomerular diseases. J Am Soc Nephrol 2003 0.90
112 Lipid droplet accumulation is associated with an increase in hyperglycemia-induced renal damage: prevention by liver X receptors. Am J Pathol 2013 0.90
113 A novel CXCL8 protein-based antagonist in acute experimental renal allograft damage. Mol Immunol 2009 0.89
114 A cut-off based approach for gene expression analysis of formalin-fixed and paraffin-embedded tissue samples. Genomics 2008 0.88
115 Dickkopf-3, an immune modulator in peripheral CD8 T-cell tolerance. Proc Natl Acad Sci U S A 2012 0.88
116 Chemokines bind to sulfatides as revealed by surface plasmon resonance. Biochim Biophys Acta 2005 0.88
117 Loss of matrix metalloproteinase-13 attenuates murine radiation-induced pulmonary fibrosis. Int J Radiat Oncol Biol Phys 2010 0.88
118 Adipocyte-specific inactivation of Acyl-CoA synthetase fatty acid transport protein 4 (Fatp4) in mice causes adipose hypertrophy and alterations in metabolism of complex lipids under high fat diet. J Biol Chem 2011 0.87
119 Chemokine receptor Ccr5 deficiency induces alternative macrophage activation and improves long-term renal allograft outcome. Eur J Immunol 2010 0.87
120 Erythropoietin gene expression in renal carcinoma is considerably more frequent than paraneoplastic polycythemia. Int J Cancer 2007 0.87
121 Glucocorticoid activity during lung maturation is essential in mesenchymal and less in alveolar epithelial cells. Mol Endocrinol 2011 0.87
122 Anti-inflammatory effects of tetrahydrobiopterin on early rejection in renal allografts: modulation of inducible nitric oxide synthase. FASEB J 2002 0.87
123 Influence of native and hypochlorite-modified low-density lipoprotein on gene expression in human proximal tubular epithelium. Am J Pathol 2004 0.87
124 RANTES is required for ischaemia-induced angiogenesis, which may hamper RANTES-targeted anti-atherosclerotic therapy. Thromb Haemost 2008 0.87
125 Inducible nitric oxide synthase in renal transplantation. Kidney Int 2002 0.87
126 Differentiation of epidermal keratinocytes is dependent on glucosylceramide:ceramide processing. Hum Mol Genet 2013 0.87
127 Selective binding and presentation of CCL5 by discrete tissue microenvironments during renal inflammation. J Am Soc Nephrol 2007 0.87
128 Met-RANTES inhibition of mucosal perfusion failure in acute intestinal transplant rejection - role of endothelial cell-leukocyte interaction. J Vasc Res 2002 0.86
129 Hepatic glycosphingolipid deficiency and liver function in mice. Hepatology 2010 0.86
130 Ala228 variant of trail receptor 1 affecting the ligand binding site is associated with chronic lymphocytic leukemia, mantle cell lymphoma, prostate cancer, head and neck squamous cell carcinoma and bladder cancer. Int J Cancer 2006 0.85
131 Hypothalamic 3',5'-cyclic adenosine monophosphate response element-binding protein loss causes anterior pituitary hypoplasia and dwarfism in mice. Mol Endocrinol 2005 0.85
132 Conditional inactivation of glucocorticoid receptor gene in dopamine-beta-hydroxylase cells impairs chromaffin cell survival. Endocrinology 2008 0.85
133 BK virus associated nephropathy in native kidneys of a heart allograft recipient. Am J Transplant 2005 0.84
134 Glycosphingolipids are essential for intestinal endocytic function. J Biol Chem 2012 0.84
135 Henoch-Schönlein purpura complicated by cardiac involvement: case report and review of the literature. Am J Kidney Dis 2009 0.84
136 Suppression of chronic damage in renal allografts by Liver X receptor (LXR) activation relevant contribution of macrophage LXRα. Am J Pathol 2011 0.83
137 In vivo role(s) of the iron regulatory proteins (IRP) 1 and 2 in aseptic local inflammation. J Mol Med (Berl) 2009 0.83
138 Growth arrest-specific protein 1 is a novel endogenous inhibitor of glomerular cell activation and proliferation. Kidney Int 2012 0.83
139 Anti-inflammatory effects of alphav integrin antagonism in acute kidney allograft rejection. Am J Pathol 2007 0.82
140 Reduced intragraft mRNA expression of matrix metalloproteinases Mmp3, Mmp12, Mmp13 and Adam8, and diminished transplant arteriosclerosis in Ccr5-deficient mice. Eur J Immunol 2004 0.82
141 Increased incidence of squamous cell carcinomas in Mastomys natalensis papillomavirus E6 transgenic mice during two-stage skin carcinogenesis. J Virol 2004 0.82
142 Cell-specific in vivo functions of glycosphingolipids: lessons from genetic deletions of enzymes involved in glycosphingolipid synthesis. Prog Lipid Res 2013 0.82
143 Prediction of renal allograft rejection by urinary protein analysis using ProteinChip Arrays (surface-enhanced laser desorption/ionization time-of-flight mass spectrometry). Urology 2006 0.82
144 Laser-controlled microdissection of tissues opens a window of new opportunities. Pathol Res Pract 2003 0.82
145 Role of xanthine oxidoreductase in experimental acute renal-allograft rejection. Transplantation 2004 0.82
146 Depletion of globosides and isoglobosides fully reverts the morphologic phenotype of Fabry disease. Cell Tissue Res 2014 0.82
147 Met-RANTES reduces endothelial progenitor cell homing to activated (glomerular) endothelium in vitro and in vivo. Am J Physiol Renal Physiol 2007 0.81
148 CD166/ALCAM mediates proinflammatory effects of S100B in delayed type hypersensitivity. J Immunol 2013 0.80
149 1-O-acylceramides are natural components of human and mouse epidermis. J Lipid Res 2013 0.80
150 Rhoh deficiency reduces peripheral T-cell function and attenuates allogenic transplant rejection. Eur J Immunol 2010 0.80
151 Polyomavirus DNA and RNA detection in renal allograft biopsies: results from a European multicenter study. Transplantation 2005 0.80
152 Glucocorticoids attenuate acute graft-versus-host disease by suppressing the cytotoxic capacity of CD8(+) T cells. J Pathol 2015 0.80
153 Effect of the antioxidant idebenone on adverse events under mycophenolate mofetil therapy in a rat model. Transplantation 2008 0.79
154 STAT-1 decoy oligodeoxynucleotide inhibition of acute rejection in mouse heart transplants. Basic Res Cardiol 2009 0.79
155 Epidemiology of glomerulonephritis in Northern Germany. Int Urol Nephrol 2011 0.79
156 Histiocytosis X and renal insufficiency. Nephrol Dial Transplant 2007 0.78
157 Cryoglobulinaemia type III with severe neuropathy and immune complex glomerulonephritis: remission after plasmapheresis and rituximab. Rheumatol Int 2007 0.78
158 Expression of the potassium channel ROMK in adult and fetal human kidney. Histochem Cell Biol 2005 0.78
159 Screening and differential diagnosis of renal light chain-associated diseases. Kidney Blood Press Res 2011 0.78
160 Does hyperlipidemia injure the kidney? Nat Clin Pract Nephrol 2008 0.78
161 Generation of GPI-linked CCL5 based chemokine receptor antagonists for the suppression of acute vascular damage during allograft transplantation. Protein Eng Des Sel 2005 0.77
162 Intraendosomal flow cytometry: a novel approach to analyze the protein composition of antigen-loaded endosomes. Eur J Immunol 2012 0.77
163 A new, robust, and nonradioactive approach for exploring N-myristoylation. J Lipid Res 2012 0.77
164 Renal lipidosis in patients enrolled in a methadone substitution program. Arch Pathol Lab Med 2014 0.76
165 Forkhead factors regulate epithelial plasticity: impact on cancer progression. Cell Cycle 2011 0.76
166 Inhibition of Comt with tolcapone slows progression of polycystic kidney disease in the more severely affected PKD/Mhm (cy/+) substrain of the Hannover Sprague-Dawley rat. Nephrol Dial Transplant 2013 0.76
167 Correction: E6 and E7 from Beta Hpv38 Cooperate with Ultraviolet Light in the Development of Actinic Keratosis-Like Lesions and Squamous Cell Carcinoma in Mice. PLoS Pathog 2016 0.75
168 Viral macrophage inflammatory protein-II improves acute rejection in allogeneic rat kidney transplants. World J Urol 2010 0.75
169 Interstitial nephritis and autoimmune pancreatitis: a case report. Int Urol Nephrol 2010 0.75
170 A Friday afternoon case of apparent anti-glomerular basement nephritis. Nephrol Dial Transplant 2006 0.75
171 Long-term kidney allograft survival in patients with transplant glomerulitis. Transplantation 2015 0.75
172 [Treatment of idiopathic membranous nephropathy. Is the anti-CD20 antibody rituximab a reasonable option?]. Med Klin (Munich) 2008 0.75
173 [Oscillation between BK virus nephropathy and rejection--the frustrating course of a living donor transplantation]. Med Klin (Munich) 2009 0.75