Published in Int J Antimicrob Agents on January 03, 2008
Efflux-mediated drug resistance in bacteria: an update. Drugs (2009) 3.18
A Mycobacterium tuberculosis sigma factor network responds to cell-envelope damage by the promising anti-mycobacterial thioridazine. PLoS One (2010) 1.32
The intrinsic resistome of bacterial pathogens. Front Microbiol (2013) 1.05
Fluorometric determination of ethidium bromide efflux kinetics in Escherichia coli. J Biol Eng (2009) 1.05
The anti-inflammatory non-antibiotic helper compound diclofenac: an antibacterial drug target. Eur J Clin Microbiol Infect Dis (2009) 0.88
Random mutagenesis of the multidrug transporter AcrB from Escherichia coli for identification of putative target residues of efflux pump inhibitors. Antimicrob Agents Chemother (2014) 0.85
Resveratrol induced inhibition of Escherichia coli proceeds via membrane oxidation and independent of diffusible reactive oxygen species generation. Redox Biol (2014) 0.82
Pimozide Inhibits the AcrAB-TolC Efflux Pump in Escherichia coli. Open Microbiol J (2013) 0.81
New Insights in to the Intrinsic and Acquired Drug Resistance Mechanisms in Mycobacteria. Front Microbiol (2017) 0.79
A Simple Method for Assessment of MDR Bacteria for Over-Expressed Efflux Pumps. Open Microbiol J (2013) 0.79
Experimental analyses of synergistic combinations of antibiotics with a recently recognised antibacterial agent, lacidipine. Eur J Clin Microbiol Infect Dis (2009) 0.78
In vitro and in vivo efficacies of amlodipine against Listeria monocytogenes. Eur J Clin Microbiol Infect Dis (2009) 0.77
Antibacterial & antitoxic effects of the cardiovascular drug lacidipine in an animal model. Indian J Med Res (2012) 0.76
The Influence of Efflux Pump Inhibitors on the Activity of Non-Antibiotic NSAIDS against Gram-Negative Rods. PLoS One (2016) 0.76
UV-light effects on cytochrome c modulated by the aggregation state of phenothiazines. PLoS One (2013) 0.76
Recent Advances in Multi-Drug Resistance (MDR) Efflux Pump Inhibitors of Gram-Positive Bacteria S. aureus. Antibiotics (Basel) (2013) 0.76
Antimicrobial Treatment of Polymeric Medical Devices by Silver Nanomaterials and Related Technology. Int J Mol Sci (2017) 0.75
Role of Phenothiazines and Structurally Similar Compounds of Plant Origin in the Fight against Infections by Drug Resistant Bacteria. Antibiotics (Basel) (2013) 0.75
Evaluation of combination therapy for Burkholderia cenocepacia lung infection in different in vitro and in vivo models. PLoS One (2017) 0.75
Broad-specificity efflux pumps and their role in multidrug resistance of Gram-negative bacteria. FEMS Microbiol Rev (2011) 2.46
The AcrAB-TolC efflux pump contributes to multidrug resistance in the nosocomial pathogen Enterobacter aerogenes. Antimicrob Agents Chemother (2002) 1.92
Emergence and control of fluoroquinolone-resistant, toxin A-negative, toxin B-positive Clostridium difficile. Infect Control Hosp Epidemiol (2007) 1.64
Antimicrobial resistance and genetic diversity of Shigella sonnei isolates from western Ireland, an area of low incidence of infection. J Clin Microbiol (2003) 1.61
Antibiotic stress, genetic response and altered permeability of E. coli. PLoS One (2007) 1.50
Biological activity of persimmon (Diospyros kaki) peel extracts. Phytother Res (2003) 1.49
Neutral genomic microevolution of a recently emerged pathogen, Salmonella enterica serovar Agona. PLoS Genet (2013) 1.48
Contribution of efflux to the emergence of isoniazid and multidrug resistance in Mycobacterium tuberculosis. PLoS One (2012) 1.46
Increased Interleukin-4 production by CD8 and gammadelta T cells in health-care workers is associated with the subsequent development of active tuberculosis. J Infect Dis (2004) 1.45
Antibiotic efflux pumps in Gram-negative bacteria: the inhibitor response strategy. J Antimicrob Chemother (2007) 1.43
Mechanisms of drug efflux and strategies to combat them: challenging the efflux pump of Gram-negative bacteria. Biochim Biophys Acta (2008) 1.40
Biological activity of barbados cherry (acerola fruits, fruit of Malpighia emarginata DC) extracts and fractions. Phytother Res (2004) 1.32
Antimicrobial and antiplasmid activities of essential oils. Fitoterapia (2006) 1.32
Inducement and reversal of tetracycline resistance in Escherichia coli K-12 and expression of proton gradient-dependent multidrug efflux pump genes. Antimicrob Agents Chemother (2005) 1.31
Detection and prevalence of active drug efflux mechanism in various multidrug-resistant Klebsiella pneumoniae strains from Turkey. J Clin Microbiol (2004) 1.30
Isoniazid-induced transient high-level resistance in Mycobacterium tuberculosis. Antimicrob Agents Chemother (2002) 1.30
Clinical concentrations of thioridazine kill intracellular multidrug-resistant Mycobacterium tuberculosis. Antimicrob Agents Chemother (2003) 1.30
Chloramphenicol and expression of multidrug efflux pump in Enterobacter aerogenes. Biochem Biophys Res Commun (2005) 1.29
Alkylaminoquinolines inhibit the bacterial antibiotic efflux pump in multidrug-resistant clinical isolates. Biochem J (2003) 1.28
Membrane permeability and regulation of drug "influx and efflux" in enterobacterial pathogens. Curr Drug Targets (2008) 1.26
Modification of outer membrane protein profile and evidence suggesting an active drug pump in Enterobacter aerogenes clinical strains. Antimicrob Agents Chemother (2003) 1.26
Geraniol restores antibiotic activities against multidrug-resistant isolates from gram-negative species. Antimicrob Agents Chemother (2009) 1.26
Efflux pumps are involved in the defense of Gram-negative bacteria against the natural products isobavachalcone and diospyrone. Antimicrob Agents Chemother (2010) 1.25
mar Operon involved in multidrug resistance of Enterobacter aerogenes. Antimicrob Agents Chemother (2002) 1.23
Contribution of efflux activity to isoniazid resistance in the Mycobacterium tuberculosis complex. Infect Genet Evol (2011) 1.22
A global plan for burn prevention and care. Bull World Health Organ (2009) 1.21
Quinoline and cyanine dyes--putative anti-MRSA drugs. Int J Antimicrob Agents (2003) 1.21
Phenothiazines and thioxanthenes inhibit multidrug efflux pump activity in Staphylococcus aureus. Antimicrob Agents Chemother (2003) 1.21
The AcrAB-TolC pump is involved in macrolide resistance but not in telithromycin efflux in Enterobacter aerogenes and Escherichia coli. Antimicrob Agents Chemother (2004) 1.20
Multiple regulatory pathways associated with high-level ciprofloxacin and multidrug resistance in Salmonella enterica serovar enteritidis: involvement of RamA and other global regulators. Antimicrob Agents Chemother (2008) 1.20
Enhanced killing of intracellular multidrug-resistant Mycobacterium tuberculosis by compounds that affect the activity of efflux pumps. J Antimicrob Chemother (2007) 1.19
Alteration of pore properties of Escherichia coli OmpF induced by mutation of key residues in anti-loop 3 region. Biochem J (2002) 1.18
Successive emergence of Enterobacter aerogenes strains resistant to imipenem and colistin in a patient. Antimicrob Agents Chemother (2005) 1.14
Implication of porins in beta-lactam resistance of Providencia stuartii. J Biol Chem (2010) 1.14
Identification of an OprD homologue in Acinetobacter baumannii. J Proteome Res (2005) 1.12
Inhibitors of antibiotic efflux pump in resistant Enterobacter aerogenes strains. Biochem Biophys Res Commun (2002) 1.11
Comparison of fasciotomy wound closures using traditional dressing changes and the vacuum-assisted closure device. Ann Plast Surg (2009) 1.09
Inhibitors of bacterial efflux pumps as adjuvants in antibiotic treatments and diagnostic tools for detection of resistance by efflux. Recent Pat Antiinfect Drug Discov (2006) 1.09
Molecular basis of macrolide resistance in Campylobacter: role of efflux pumps and target mutations. J Antimicrob Chemother (2005) 1.08
Structural and functional study of the phenicol-specific efflux pump FloR belonging to the major facilitator superfamily. Antimicrob Agents Chemother (2005) 1.08
Demonstration of intrinsic efflux activity of Escherichia coli K-12 AG100 by an automated ethidium bromide method. Int J Antimicrob Agents (2008) 1.07
Strategies for bypassing the membrane barrier in multidrug resistant Gram-negative bacteria. FEBS Lett (2011) 1.06
Identification and evolution of drug efflux pump in clinical Enterobacter aerogenes strains isolated in 1995 and 2003. PLoS One (2008) 1.06
Ethidium bromide transport across Mycobacterium smegmatis cell-wall: correlation with antibiotic resistance. BMC Microbiol (2011) 1.06
Resistance to imipenem, cefepime, and cefpirome associated with mutation in Omp36 osmoporin of Enterobacter aerogenes. Biochem Biophys Res Commun (2004) 1.05
Fluorometric determination of ethidium bromide efflux kinetics in Escherichia coli. J Biol Eng (2009) 1.05
Cost-based analysis of the treatment of mandibular fractures in a tertiary care center. J Trauma (2003) 1.05
Efflux-mediated response of Staphylococcus aureus exposed to ethidium bromide. J Antimicrob Chemother (2008) 1.04
Exploring the contribution of efflux on the resistance to fluoroquinolones in clinical isolates of Staphylococcus aureus. BMC Microbiol (2011) 1.04
Imipenem and expression of multidrug efflux pump in Enterobacter aerogenes. Biochem Biophys Res Commun (2003) 1.04
Intracellular accumulation of linezolid in Escherichia coli, Citrobacter freundii and Enterobacter aerogenes: role of enhanced efflux pump activity and inactivation. J Antimicrob Chemother (2006) 1.04
How beta-lactam antibiotics enter bacteria: a dialogue with the porins. PLoS One (2009) 1.04
Antibacterial activity of Thymus maroccanus and Thymus broussonetii essential oils against nosocomial infection - bacteria and their synergistic potential with antibiotics. Phytomedicine (2012) 1.03
Characterization of antimicrobial resistance in Salmonella enterica food and animal isolates from Colombia: identification of a qnrB19-mediated quinolone resistance marker in two novel serovars. FEMS Microbiol Lett (2010) 1.00
High-level resistance to isoniazid and ethionamide in multidrug-resistant Mycobacterium tuberculosis of the Lisboa family is associated with inhA double mutations. J Antimicrob Chemother (2013) 1.00
Coumarin derivatives with tumor-specific cytotoxicity and multidrug resistance reversal activity. In Vivo (2005) 1.00
Membrane efflux and influx modulate both multidrug resistance and virulence of Klebsiella pneumoniae in a Caenorhabditis elegans model. Antimicrob Agents Chemother (2010) 0.99
Beta-lactam screening by specific residues of the OmpF eyelet. J Med Chem (2005) 0.99
The antipsychotic thioridazine shows promising therapeutic activity in a mouse model of multidrug-resistant tuberculosis. PLoS One (2010) 0.99
Distinct synergistic action of piperacillin and methylglyoxal against Pseudomonas aeruginosa. Indian J Exp Biol (2011) 0.98
The curative activity of thioridazine on mice infected with Mycobacterium tuberculosis. In Vivo (2007) 0.98
Thioridazine and chlorpromazine inhibition of ethidium bromide efflux in Mycobacterium avium and Mycobacterium smegmatis. J Antimicrob Chemother (2008) 0.98
Quinoline derivatives as promising inhibitors of antibiotic efflux pump in multidrug resistant Enterobacter aerogenes isolates. Curr Drug Targets (2006) 0.98
Intracellular activity of clinical concentrations of phenothiazines including thioridiazine against phagocytosed Staphylococcus aureus. Int J Antimicrob Agents (2002) 0.97
Gold on paper-paper platform for Au-nanoprobe TB detection. Lab Chip (2012) 0.97
A phenylalanine-arginine beta-naphthylamide sensitive multidrug efflux pump involved in intrinsic and acquired resistance of Campylobacter to macrolides. Int J Antimicrob Agents (2003) 0.97
The role of efflux pumps in macrolide resistance in Mycobacterium avium complex. Int J Antimicrob Agents (2009) 0.96
Identification and characterization of five new molecular serogroups of Cronobacter spp. Foodborne Pathog Dis (2013) 0.96
Inhibitors of antibiotic efflux in resistant Enterobacter aerogenes and Klebsiella pneumoniae strains. Antimicrob Agents Chemother (2004) 0.96
Amlodipine: a cardiovascular drug with powerful antimicrobial property. Acta Microbiol Pol (2003) 0.95
Multidrug Efflux Pumps in Staphylococcus aureus: an Update. Open Microbiol J (2013) 0.95
Squalamine: an appropriate strategy against the emergence of multidrug resistant gram-negative bacteria? PLoS One (2008) 0.95
Effect of cycloartanes on reversal of multidrug resistance and apoptosis induction on mouse lymphoma cells. Anticancer Res (2004) 0.95
An instrument-free method for the demonstration of efflux pump activity of bacteria. In Vivo (2006) 0.94
Antimicrobial activity of phenothiazines. In Vivo (2005) 0.94
Enterobacter aerogenes OmpX, a cation-selective channel mar- and osmo-regulated. FEBS Lett (2004) 0.94
Evaluation of efflux activity of bacteria by a semi-automated fluorometric system. Methods Mol Biol (2010) 0.94
Mycobacterial efflux pumps and chemotherapeutic implications. Int J Antimicrob Agents (2003) 0.94