Published in BMC Microbiol on January 08, 2008
RNAIII-independent target gene control by the agr quorum-sensing system: insight into the evolution of virulence regulation in Staphylococcus aureus. Mol Cell (2008) 3.44
The importance of a multifaceted approach to characterizing the microbial flora of chronic wounds. Wound Repair Regen (2011) 2.09
Current concepts in biofilm formation of Staphylococcus epidermidis. Future Microbiol (2010) 1.67
Methylthioadenosine/S-adenosylhomocysteine nucleosidase, a critical enzyme for bacterial metabolism. Mol Microbiol (2010) 1.56
Molecular basis of Staphylococcus epidermidis infections. Semin Immunopathol (2011) 1.56
Sinorhizobium meliloti, a bacterium lacking the autoinducer-2 (AI-2) synthase, responds to AI-2 supplied by other bacteria. Mol Microbiol (2008) 1.15
Analysis of bacterial biofilms using NMR-based metabolomics. Future Med Chem (2012) 1.11
Staphylococcus aureus AI-2 quorum sensing associates with the KdpDE two-component system to regulate capsular polysaccharide synthesis and virulence. Infect Immun (2010) 1.10
Novel phenol-soluble modulin derivatives in community-associated methicillin-resistant Staphylococcus aureus identified through imaging mass spectrometry. J Biol Chem (2012) 1.08
Identification of functional LsrB-like autoinducer-2 receptors. J Bacteriol (2009) 1.06
Furanone at subinhibitory concentrations enhances staphylococcal biofilm formation by luxS repression. Antimicrob Agents Chemother (2009) 1.06
Genetic regulation of the intercellular adhesion locus in staphylococci. Front Cell Infect Microbiol (2012) 0.97
Bench-to-bedside review: Quorum sensing and the role of cell-to-cell communication during invasive bacterial infection. Crit Care (2008) 0.95
Optimizing a qPCR gene expression quantification assay for S. epidermidis biofilms: a comparison between commercial kits and a customized protocol. PLoS One (2012) 0.91
Enzyme-ligand interactions that drive active site rearrangements in the Helicobacter pylori 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase. Protein Sci (2010) 0.86
Detection of AI-2 receptors in genomes of Enterobacteriaceae suggests a role of type-2 quorum sensing in closed ecosystems. Sensors (Basel) (2012) 0.84
The crystal structure of the Escherichia coli autoinducer-2 processing protein LsrF. PLoS One (2009) 0.83
Quorum-sensing regulation in staphylococci-an overview. Front Microbiol (2015) 0.81
The Staphylococcal Biofilm: Adhesins, Regulation, and Host Response. Microbiol Spectr (2016) 0.79
Anti-Biofilm Activity of a Long-Chain Fatty Aldehyde from Antarctic Pseudoalteromonas haloplanktis TAC125 against Staphylococcus epidermidis Biofilm. Front Cell Infect Microbiol (2017) 0.75
Autoinducer 2 Signaling via the Phosphotransferase FruA Drives Galactose Utilization by Streptococcus pneumoniae, Resulting in Hypervirulence. MBio (2017) 0.75
Identification of novel cytolytic peptides as key virulence determinants for community-associated MRSA. Nat Med (2007) 7.75
Quorum sensing in Escherichia coli, Salmonella typhimurium, and Vibrio harveyi: a new family of genes responsible for autoinducer production. Proc Natl Acad Sci U S A (1999) 6.89
The LuxS family of bacterial autoinducers: biosynthesis of a novel quorum-sensing signal molecule. Mol Microbiol (2001) 6.27
Cross-species induction of luminescence in the quorum-sensing bacterium Vibrio harveyi. J Bacteriol (1997) 5.93
Bacterial small-molecule signaling pathways. Science (2006) 5.14
The cidA murein hydrolase regulator contributes to DNA release and biofilm development in Staphylococcus aureus. Proc Natl Acad Sci U S A (2007) 4.07
LuxS quorum sensing: more than just a numbers game. Curr Opin Microbiol (2003) 3.76
Staphylococcus epidermidis infections. Microbes Infect (2002) 3.45
Making 'sense' of metabolism: autoinducer-2, LuxS and pathogenic bacteria. Nat Rev Microbiol (2005) 3.20
The LuxS-dependent autoinducer AI-2 controls the expression of an ABC transporter that functions in AI-2 uptake in Salmonella typhimurium. Mol Microbiol (2001) 3.15
Quorum-sensing control of biofilm factors in Staphylococcus epidermidis. J Infect Dis (2003) 2.82
LuxS: its role in central metabolism and the in vitro synthesis of 4-hydroxy-5-methyl-3(2H)-furanone. Microbiology (2002) 2.61
Interspecies communication in bacteria. J Clin Invest (2003) 2.55
Lsr-mediated transport and processing of AI-2 in Salmonella typhimurium. Mol Microbiol (2003) 2.47
Gram-positive three-component antimicrobial peptide-sensing system. Proc Natl Acad Sci U S A (2007) 2.34
Mutation of luxS affects biofilm formation in Streptococcus mutans. Infect Immun (2003) 2.34
LuxS-based signaling in Streptococcus gordonii: autoinducer 2 controls carbohydrate metabolism and biofilm formation with Porphyromonas gingivalis. J Bacteriol (2003) 2.31
Staphylococcus quorum sensing in biofilm formation and infection. Int J Med Microbiol (2006) 2.25
Mutation of luxS affects growth and virulence factor expression in Streptococcus pyogenes. Mol Microbiol (2001) 2.20
Regulation of LuxPQ receptor activity by the quorum-sensing signal autoinducer-2. Mol Cell (2005) 1.94
Death's toolbox: examining the molecular components of bacterial programmed cell death. Mol Microbiol (2003) 1.93
Is autoinducer-2 a universal signal for interspecies communication: a comparative genomic and phylogenetic analysis of the synthesis and signal transduction pathways. BMC Evol Biol (2004) 1.86
Staphylococcus epidermidis: emerging resistance and need for alternative agents. Clin Infect Dis (1998) 1.83
An inflammatory polypeptide complex from Staphylococcus epidermidis: isolation and characterization. J Exp Med (1999) 1.82
Regulated expression of pathogen-associated molecular pattern molecules in Staphylococcus epidermidis: quorum-sensing determines pro-inflammatory capacity and production of phenol-soluble modulins. Cell Microbiol (2004) 1.74
YdgG (TqsA) controls biofilm formation in Escherichia coli K-12 through autoinducer 2 transport. J Bacteriol (2006) 1.58
Role of the luxS quorum-sensing system in biofilm formation and virulence of Staphylococcus epidermidis. Infect Immun (2006) 1.51
Characterization of type 2 quorum sensing in Klebsiella pneumoniae and relationship with biofilm formation. J Bacteriol (2005) 1.50
Quorum sensing in Campylobacter jejuni: detection of a luxS encoded signalling molecule. Microbiology (2002) 1.46
Virulence factors of the coagulase-negative staphylococci. Front Biosci (2004) 1.44
Construction and characterization of an agr deletion mutant of Staphylococcus epidermidis. Infect Immun (2000) 1.39
Autoinducer 2 affects biofilm formation by Bacillus cereus. Appl Environ Microbiol (2006) 1.35
Mutation of luxS of Streptococcus pneumoniae affects virulence in a mouse model. Infect Immun (2003) 1.29
Functional analysis of luxS in Staphylococcus aureus reveals a role in metabolism but not quorum sensing. J Bacteriol (2006) 1.27
Quorum sensing and expression of virulence in Escherichia coli O157:H7. Int J Food Microbiol (2003) 0.94
Quorum sensing in Vibrio harveyi: probing the specificity of the LuxP binding site. Bioorg Med Chem Lett (2005) 0.93
Community-associated meticillin-resistant Staphylococcus aureus. Lancet (2010) 9.07
Is Panton-Valentine leukocidin the major virulence determinant in community-associated methicillin-resistant Staphylococcus aureus disease? J Infect Dis (2006) 8.17
Identification of novel cytolytic peptides as key virulence determinants for community-associated MRSA. Nat Med (2007) 7.75
Poring over pores: alpha-hemolysin and Panton-Valentine leukocidin in Staphylococcus aureus pneumonia. Nat Med (2007) 5.95
Insights into mechanisms used by Staphylococcus aureus to avoid destruction by human neutrophils. J Immunol (2005) 5.18
Genome sequence and comparative microarray analysis of serotype M18 group A Streptococcus strains associated with acute rheumatic fever outbreaks. Proc Natl Acad Sci U S A (2002) 4.85
Epidemic community-associated methicillin-resistant Staphylococcus aureus: recent clonal expansion and diversification. Proc Natl Acad Sci U S A (2008) 4.38
Panton-Valentine leukocidin is not a virulence determinant in murine models of community-associated methicillin-resistant Staphylococcus aureus disease. J Infect Dis (2008) 4.16
Evolution of virulence in epidemic community-associated methicillin-resistant Staphylococcus aureus. Proc Natl Acad Sci U S A (2009) 3.89
Evolutionary origin and emergence of a highly successful clone of serotype M1 group a Streptococcus involved multiple horizontal gene transfer events. J Infect Dis (2005) 3.89
Virulence control in group A Streptococcus by a two-component gene regulatory system: global expression profiling and in vivo infection modeling. Proc Natl Acad Sci U S A (2002) 3.83
Staphylococcus epidermidis infections. Microbes Infect (2002) 3.45
RNAIII-independent target gene control by the agr quorum-sensing system: insight into the evolution of virulence regulation in Staphylococcus aureus. Mol Cell (2008) 3.44
Polysaccharide intercellular adhesin (PIA) protects Staphylococcus epidermidis against major components of the human innate immune system. Cell Microbiol (2004) 3.26
A crucial role for exopolysaccharide modification in bacterial biofilm formation, immune evasion, and virulence. J Biol Chem (2004) 3.05
Quorum-sensing control of biofilm factors in Staphylococcus epidermidis. J Infect Dis (2003) 2.82
The role of virulence determinants in community-associated MRSA pathogenesis. Trends Microbiol (2008) 2.78
Human formyl peptide receptor 2 senses highly pathogenic Staphylococcus aureus. Cell Host Microbe (2010) 2.64
Contribution of Panton-Valentine leukocidin in community-associated methicillin-resistant Staphylococcus aureus pathogenesis. PLoS One (2008) 2.62
MRSA epidemic linked to a quickly spreading colonization and virulence determinant. Nat Med (2012) 2.61
Global changes in Staphylococcus aureus gene expression in human blood. PLoS One (2011) 2.61
Essential Staphylococcus aureus toxin export system. Nat Med (2013) 2.50
Plasmodium falciparum genome-wide scans for positive selection, recombination hot spots and resistance to antimalarial drugs. Nat Genet (2010) 2.48
The antimicrobial peptide-sensing system aps of Staphylococcus aureus. Mol Microbiol (2007) 2.45
How Staphylococcus aureus biofilms develop their characteristic structure. Proc Natl Acad Sci U S A (2012) 2.43
Host cell-free growth of the Q fever bacterium Coxiella burnetii. Proc Natl Acad Sci U S A (2009) 2.38
Gram-positive three-component antimicrobial peptide-sensing system. Proc Natl Acad Sci U S A (2007) 2.34
The Chlamydia trachomatis plasmid is a transcriptional regulator of chromosomal genes and a virulence factor. Infect Immun (2008) 2.34
Genome-wide molecular dissection of serotype M3 group A Streptococcus strains causing two epidemics of invasive infections. Proc Natl Acad Sci U S A (2004) 2.32
Staphylococcus quorum sensing in biofilm formation and infection. Int J Med Microbiol (2006) 2.25
Apolipoprotein B Is an innate barrier against invasive Staphylococcus aureus infection. Cell Host Microbe (2008) 2.20
Comparative analysis of USA300 virulence determinants in a rabbit model of skin and soft tissue infection. J Infect Dis (2011) 2.19
Selective antimicrobial action is provided by phenol-soluble modulins derived from Staphylococcus epidermidis, a normal resident of the skin. J Invest Dermatol (2010) 2.13
Comparative analysis of virulence and toxin expression of global community-associated methicillin-resistant Staphylococcus aureus strains. J Infect Dis (2010) 2.13
A point mutation in the agr locus rather than expression of the Panton-Valentine leukocidin caused previously reported phenotypes in Staphylococcus aureus pneumonia and gene regulation. J Infect Dis (2009) 2.12
Genomewide analysis of gene expression in Staphylococcus epidermidis biofilms: insights into the pathophysiology of S. epidermidis biofilms and the role of phenol-soluble modulins in formation of biofilms. J Infect Dis (2004) 2.09
Host defense and pathogenesis in Staphylococcus aureus infections. Infect Dis Clin North Am (2009) 2.01
Staphylococcus epidermidis surfactant peptides promote biofilm maturation and dissemination of biofilm-associated infection in mice. J Clin Invest (2010) 2.00
Genome-wide protective response used by group A Streptococcus to evade destruction by human polymorphonuclear leukocytes. Proc Natl Acad Sci U S A (2003) 1.99
Neutrophil microbicides induce a pathogen survival response in community-associated methicillin-resistant Staphylococcus aureus. J Immunol (2008) 1.97
Mobile genetic element-encoded cytolysin connects virulence to methicillin resistance in MRSA. PLoS Pathog (2009) 1.89
Increased colonization of indwelling medical devices by quorum-sensing mutants of Staphylococcus epidermidis in vivo. J Infect Dis (2004) 1.86
Chlamydia trachomatis plasmid-encoded Pgp4 is a transcriptional regulator of virulence-associated genes. Infect Immun (2013) 1.82
Role of the accessory gene regulator agr in community-associated methicillin-resistant Staphylococcus aureus pathogenesis. Infect Immun (2011) 1.79
Rgg influences the expression of multiple regulatory loci to coregulate virulence factor expression in Streptococcus pyogenes. Infect Immun (2002) 1.78
The SaeR/S gene regulatory system is essential for innate immune evasion by Staphylococcus aureus. J Infect Dis (2009) 1.74
Regulated expression of pathogen-associated molecular pattern molecules in Staphylococcus epidermidis: quorum-sensing determines pro-inflammatory capacity and production of phenol-soluble modulins. Cell Microbiol (2004) 1.74
Staphylococcus aureus Panton-Valentine leukocidin contributes to inflammation and muscle tissue injury. PLoS One (2009) 1.74
Molecular differentiation of historic phage-type 80/81 and contemporary epidemic Staphylococcus aureus. Proc Natl Acad Sci U S A (2011) 1.70
Polymorphisms in the Chlamydia trachomatis cytotoxin locus associated with ocular and genital isolates. Infect Immun (2004) 1.68
Adaptive response of Yersinia pestis to extracellular effectors of innate immunity during bubonic plague. Proc Natl Acad Sci U S A (2006) 1.66
Key role of poly-gamma-DL-glutamic acid in immune evasion and virulence of Staphylococcus epidermidis. J Clin Invest (2005) 1.64
Rapid neutrophil destruction following phagocytosis of Staphylococcus aureus. J Innate Immun (2010) 1.62
Staphylococcus epidermidis strategies to avoid killing by human neutrophils. PLoS Pathog (2010) 1.60
Synthesis and deformylation of Staphylococcus aureus delta-toxin are linked to tricarboxylic acid cycle activity. J Bacteriol (2003) 1.59
Phenol-soluble modulins and staphylococcal infection. Nat Rev Microbiol (2013) 1.56
Staphylococcus δ-toxin induces allergic skin disease by activating mast cells. Nature (2013) 1.56
Antimicrobial activity of community-associated methicillin-resistant Staphylococcus aureus is caused by phenol-soluble modulin derivatives. J Biol Chem (2011) 1.51
Role of the luxS quorum-sensing system in biofilm formation and virulence of Staphylococcus epidermidis. Infect Immun (2006) 1.51
The human anionic antimicrobial peptide dermcidin induces proteolytic defence mechanisms in staphylococci. Mol Microbiol (2006) 1.46
Genomic comparison of virulent Rickettsia rickettsii Sheila Smith and avirulent Rickettsia rickettsii Iowa. Infect Immun (2007) 1.46
Staphylococcus epidermidis polysaccharide intercellular adhesin production significantly increases during tricarboxylic acid cycle stress. J Bacteriol (2005) 1.44
Developmental stage-specific metabolic and transcriptional activity of Chlamydia trachomatis in an axenic medium. Proc Natl Acad Sci U S A (2012) 1.43
Inactivation of a bacterial virulence pheromone by phagocyte-derived oxidants: new role for the NADPH oxidase in host defense. Proc Natl Acad Sci U S A (2004) 1.42
Genetic diversity of arginine catabolic mobile element in Staphylococcus epidermidis. PLoS One (2009) 1.42
Phagocytosis of Staphylococcus aureus by macrophages exerts cytoprotective effects manifested by the upregulation of antiapoptotic factors. PLoS One (2009) 1.41
Staphylococcus epidermidis pan-genome sequence analysis reveals diversity of skin commensal and hospital infection-associated isolates. Genome Biol (2012) 1.38
Direct and synergistic hemolysis caused by Staphylococcus phenol-soluble modulins: implications for diagnosis and pathogenesis. Microbes Infect (2011) 1.37
Transit through the flea vector induces a pretransmission innate immunity resistance phenotype in Yersinia pestis. PLoS Pathog (2010) 1.36
Defining the strain-dependent impact of the Staphylococcal accessory regulator (sarA) on the alpha-toxin phenotype of Staphylococcus aureus. J Bacteriol (2011) 1.36
Neutrophil responses to staphylococcal pathogens and commensals via the formyl peptide receptor 2 relates to phenol-soluble modulin release and virulence. FASEB J (2010) 1.31
Glycosylation of wall teichoic acid in Staphylococcus aureus by TarM. J Biol Chem (2010) 1.29
Induction of Salmonella pathogenicity island 1 under different growth conditions can affect Salmonella-host cell interactions in vitro. Microbiology (2009) 1.28
Staphylococcus aureus biofilm metabolism and the influence of arginine on polysaccharide intercellular adhesin synthesis, biofilm formation, and pathogenesis. Infect Immun (2007) 1.27
Characterization of the Staphylococcus epidermidis accessory-gene regulator response: quorum-sensing regulation of resistance to human innate host defense. J Infect Dis (2006) 1.25
Molecular basis of in vivo biofilm formation by bacterial pathogens. Chem Biol (2012) 1.23
Silver coordination polymers for prevention of implant infection: thiol interaction, impact on respiratory chain enzymes, and hydroxyl radical induction. Antimicrob Agents Chemother (2010) 1.22