Published in Front Microbiol on October 27, 2015
Specificity and complexity in bacterial quorum-sensing systems. FEMS Microbiol Rev (2016) 0.95
Impact of Environmental Cues on Staphylococcal Quorum Sensing and Biofilm Development. J Biol Chem (2016) 0.90
Comparative virulence studies and transcriptome analysis of Staphylococcus aureus strains isolated from animals. Sci Rep (2016) 0.79
Enhancement of the pathogenicity of Staphylococcus aureus strain Newman by a small noncoding RNA SprX1. Med Microbiol Immunol (2016) 0.77
Complete Genome Sequence of the MRSA Isolate HC1335 from ST239 Lineage Displaying a Truncated AgrC Histidine Kinase Receptor. Genome Biol Evol (2016) 0.75
Non-Woven Polymer Nanofiber Coatings that Inhibit Quorum Sensing in Staphylococcus aureus: Toward New Non-Bactericidal Approaches to Infection Control. ACS Infect Dis (2017) 0.75
The commensal lifestyle of Staphylococcus aureus and its interactions with the nasal microbiota. Nat Rev Microbiol (2017) 0.75
Staphylococcus aureus infections. N Engl J Med (1998) 36.39
Quorum sensing: cell-to-cell communication in bacteria. Annu Rev Cell Dev Biol (2005) 13.88
Synthesis of staphylococcal virulence factors is controlled by a regulatory RNA molecule. EMBO J (1993) 11.30
Cloning, characterization, and sequencing of an accessory gene regulator (agr) in Staphylococcus aureus. J Bacteriol (1988) 8.18
Structural identification of a bacterial quorum-sensing signal containing boron. Nature (2002) 8.11
Bacterial interference caused by autoinducing peptide variants. Science (1997) 7.96
Identification of novel cytolytic peptides as key virulence determinants for community-associated MRSA. Nat Med (2007) 7.75
Cell density control of staphylococcal virulence mediated by an octapeptide pheromone. Proc Natl Acad Sci U S A (1995) 6.13
Poring over pores: alpha-hemolysin and Panton-Valentine leukocidin in Staphylococcus aureus pneumonia. Nat Med (2007) 5.95
Cross-species induction of luminescence in the quorum-sensing bacterium Vibrio harveyi. J Bacteriol (1997) 5.93
Transcription profiling-based identification of Staphylococcus aureus genes regulated by the agr and/or sarA loci. J Bacteriol (2001) 5.57
Staphylococcus epidermidis--the 'accidental' pathogen. Nat Rev Microbiol (2009) 5.34
The agr P2 operon: an autocatalytic sensory transduction system in Staphylococcus aureus. Mol Gen Genet (1995) 4.63
Role of the accessory gene regulator (agr) in pathogenesis of staphylococcal osteomyelitis. Infect Immun (1995) 4.58
Quorum sensing in staphylococci. Annu Rev Genet (2008) 4.58
Diminished virulence of a sar-/agr- mutant of Staphylococcus aureus in the rabbit model of endocarditis. J Clin Invest (1994) 4.39
Quorum sensing by peptide pheromones and two-component signal-transduction systems in Gram-positive bacteria. Mol Microbiol (1997) 4.28
Small talk. Cell-to-cell communication in bacteria. Cell (2002) 4.27
Staphylococcal biofilms. Curr Top Microbiol Immunol (2008) 4.26
Impact of the agr quorum-sensing system on adherence to polystyrene in Staphylococcus aureus. J Infect Dis (2000) 4.19
Targeting of alpha-hemolysin by active or passive immunization decreases severity of USA300 skin infection in a mouse model. J Infect Dis (2010) 4.19
The accessory gene regulator (agr) controls Staphylococcus aureus virulence in a murine arthritis model. Infect Immun (1993) 4.00
Staphylococcus aureus protein A induces airway epithelial inflammatory responses by activating TNFR1. Nat Med (2004) 3.84
Identification and nucleotide sequence of the delta-lysin gene, hld, adjacent to the accessory gene regulator (agr) of Staphylococcus aureus. Mol Gen Genet (1989) 3.80
Structure-activity analysis of synthetic autoinducing thiolactone peptides from Staphylococcus aureus responsible for virulence. Proc Natl Acad Sci U S A (1999) 3.79
Activation of alpha-toxin translation in Staphylococcus aureus by the trans-encoded antisense RNA, RNAIII. EMBO J (1995) 3.64
RNAIII-independent target gene control by the agr quorum-sensing system: insight into the evolution of virulence regulation in Staphylococcus aureus. Mol Cell (2008) 3.44
Surface proteins and exotoxins are required for the pathogenesis of Staphylococcus aureus pneumonia. Infect Immun (2006) 3.41
Characterization of the sar locus and its interaction with agr in Staphylococcus aureus. J Bacteriol (1996) 3.05
Global regulation of Staphylococcus aureus genes by Rot. J Bacteriol (2003) 3.02
Staphylococcus aureus RNAIII coordinately represses the synthesis of virulence factors and the transcription regulator Rot by an antisense mechanism. Genes Dev (2007) 2.86
Persistent bacteremia due to methicillin-resistant Staphylococcus aureus infection is associated with agr dysfunction and low-level in vitro resistance to thrombin-induced platelet microbicidal protein. J Infect Dis (2004) 2.83
Quorum-sensing control of biofilm factors in Staphylococcus epidermidis. J Infect Dis (2003) 2.82
Effect of protein A on staphylococcal opsonization. Infect Immun (1977) 2.79
Transmembrane topology and histidine protein kinase activity of AgrC, the agr signal receptor in Staphylococcus aureus. Mol Microbiol (1998) 2.77
Glucose and nonmaintained pH decrease expression of the accessory gene regulator (agr) in Staphylococcus aureus. Infect Immun (1992) 2.70
LuxS: its role in central metabolism and the in vitro synthesis of 4-hydroxy-5-methyl-3(2H)-furanone. Microbiology (2002) 2.61
Role of a disintegrin and metalloprotease 10 in Staphylococcus aureus alpha-hemolysin-mediated cellular injury. Proc Natl Acad Sci U S A (2010) 2.59
Identification, cloning, and initial characterization of rot, a locus encoding a regulator of virulence factor expression in Staphylococcus aureus. J Bacteriol (2000) 2.52
How Staphylococcus aureus biofilms develop their characteristic structure. Proc Natl Acad Sci U S A (2012) 2.43
Identification of a novel two-component regulatory system that acts in global regulation of virulence factors of Staphylococcus aureus. J Bacteriol (2001) 2.33
agr function in clinical Staphylococcus aureus isolates. Microbiology (2008) 2.33
Transient interference with staphylococcal quorum sensing blocks abscess formation. Proc Natl Acad Sci U S A (2005) 2.30
Prevalence of agr dysfunction among colonizing Staphylococcus aureus strains. J Infect Dis (2008) 2.29
Infection control by antibody disruption of bacterial quorum sensing signaling. Chem Biol (2007) 2.24
Comparative analysis of USA300 virulence determinants in a rabbit model of skin and soft tissue infection. J Infect Dis (2011) 2.19
Staphylococcus epidermidis surfactant peptides promote biofilm maturation and dissemination of biofilm-associated infection in mice. J Clin Invest (2010) 2.00
Staphylococcus aureus α-toxin: nearly a century of intrigue. Toxins (Basel) (2013) 1.99
Structure of the pheromone peptide of the Staphylococcus epidermidis agr system. FEBS Lett (1998) 1.96
Staphylococcal infections: mechanisms of biofilm maturation and detachment as critical determinants of pathogenicity. Annu Rev Med (2012) 1.96
Increased colonization of indwelling medical devices by quorum-sensing mutants of Staphylococcus epidermidis in vivo. J Infect Dis (2004) 1.86
Interconnections between Sigma B, agr, and proteolytic activity in Staphylococcus aureus biofilm maturation. Infect Immun (2009) 1.86
CCR5 is a receptor for Staphylococcus aureus leukotoxin ED. Nature (2012) 1.85
Staphylococcus aureus AgrA binding to the RNAIII-agr regulatory region. J Bacteriol (2004) 1.85
Key determinants of receptor activation in the agr autoinducing peptides of Staphylococcus aureus. Biochemistry (2002) 1.84
Characterization of a novel structural member, LukE-LukD, of the bi-component staphylococcal leucotoxins family. FEBS Lett (1998) 1.81
Role of the accessory gene regulator agr in community-associated methicillin-resistant Staphylococcus aureus pathogenesis. Infect Immun (2011) 1.79
Staphylococcus aureus infection induces protein A-mediated immune evasion in humans. J Exp Med (2014) 1.74
Structure, activity and evolution of the group I thiolactone peptide quorum-sensing system of Staphylococcus aureus. Mol Microbiol (2001) 1.65
Importance of the global regulators Agr and SaeRS in the pathogenesis of CA-MRSA USA300 infection. PLoS One (2010) 1.64
Staphylococcus aureus leucocidin ED contributes to systemic infection by targeting neutrophils and promoting bacterial growth in vivo. Mol Microbiol (2011) 1.64
Protein A is a virulence factor in Staphylococcus aureus arthritis and septic death. Microb Pathog (2002) 1.61
Pheromone cross-inhibition between Staphylococcus aureus and Staphylococcus epidermidis. Infect Immun (2001) 1.59
ADAM10 mediates vascular injury induced by Staphylococcus aureus α-hemolysin. J Infect Dis (2012) 1.56
Role of the luxS quorum-sensing system in biofilm formation and virulence of Staphylococcus epidermidis. Infect Immun (2006) 1.51
Virulence factors of the coagulase-negative staphylococci. Front Biosci (2004) 1.44
Selective chemical inhibition of agr quorum sensing in Staphylococcus aureus promotes host defense with minimal impact on resistance. PLoS Pathog (2014) 1.39
Transmembrane topology of AgrB, the protein involved in the post-translational modification of AgrD in Staphylococcus aureus. J Biol Chem (2002) 1.39
Staphylococcus aureus elaborates leukocidin AB to mediate escape from within human neutrophils. Infect Immun (2013) 1.37
Staphylococcus aureus agr and sarA functions are required for invasive infection but not inflammatory responses in the lung. Infect Immun (2002) 1.36
A role for type I signal peptidase in Staphylococcus aureus quorum sensing. Mol Microbiol (2007) 1.35
The bicomponent pore-forming leucocidins of Staphylococcus aureus. Microbiol Mol Biol Rev (2014) 1.32
A secreted bacterial protease tailors the Staphylococcus aureus virulence repertoire to modulate bone remodeling during osteomyelitis. Cell Host Microbe (2013) 1.31
Mutations in agr do not persist in natural populations of methicillin-resistant Staphylococcus aureus. J Infect Dis (2010) 1.27
Functional analysis of luxS in Staphylococcus aureus reveals a role in metabolism but not quorum sensing. J Bacteriol (2006) 1.27
PSMs of hypervirulent Staphylococcus aureus act as intracellular toxins that kill infected osteoblasts. PLoS One (2013) 1.26
Characterization of the Staphylococcus epidermidis accessory-gene regulator response: quorum-sensing regulation of resistance to human innate host defense. J Infect Dis (2006) 1.25
Phenol-soluble modulins--critical determinants of staphylococcal virulence. FEMS Microbiol Rev (2014) 1.21
Extracellular proteases are key mediators of Staphylococcus aureus virulence via the global modulation of virulence-determinant stability. Microbiologyopen (2012) 1.13
AI-2-dependent gene regulation in Staphylococcus epidermidis. BMC Microbiol (2008) 1.12
Highly potent inhibitors of quorum sensing in Staphylococcus aureus revealed through a systematic synthetic study of the group-III autoinducing peptide. J Am Chem Soc (2013) 1.10
Staphylococcus aureus AI-2 quorum sensing associates with the KdpDE two-component system to regulate capsular polysaccharide synthesis and virulence. Infect Immun (2010) 1.10
Global gene expression of methicillin-resistant Staphylococcus aureus USA300 during human and mouse infection. J Infect Dis (2013) 1.07
Subinhibitory concentrations of protein synthesis-inhibiting antibiotics promote increased expression of the agr virulence regulator and production of phenol-soluble modulin cytolysins in community-associated methicillin-resistant Staphylococcus aureus. Antimicrob Agents Chemother (2010) 1.07
A MRSA-terious enemy among us: end of the PVL controversy? Nat Med (2011) 1.06
Staphylococcus epidermidis agr quorum-sensing system: signal identification, cross talk, and importance in colonization. J Bacteriol (2014) 1.04
Antibiotic-mediated selection of quorum-sensing-negative Staphylococcus aureus. MBio (2013) 1.03
Staphylococcus intermedius produces a functional agr autoinducing peptide containing a cyclic lactone. J Bacteriol (2005) 1.01
Release of protein A from the cell wall of Staphylococcus aureus. Proc Natl Acad Sci U S A (2014) 0.96
Identification of a staphylococcal AgrB segment(s) responsible for group-specific processing of AgrD by gene swapping. J Bacteriol (2004) 0.93
Production of an attenuated phenol-soluble modulin variant unique to the MRSA clonal complex 30 increases severity of bloodstream infection. PLoS Pathog (2014) 0.92
Oxacillin alters the toxin expression profile of community-associated methicillin-resistant Staphylococcus aureus. Antimicrob Agents Chemother (2013) 0.92
Inducible expression and cellular location of AgrB, a protein involved in the maturation of the staphylococcal quorum-sensing pheromone. Arch Microbiol (2000) 0.89
Investigational therapies targeting quorum-sensing for the treatment of Staphylococcus aureus infections. Expert Opin Investig Drugs (2015) 0.89
LuxS/AI-2 system is involved in antibiotic susceptibility and autolysis in Staphylococcus aureus NCTC 8325. Int J Antimicrob Agents (2012) 0.88
Multivalent alteration of quorum sensing in Staphylococcus aureus. Chem Commun (Camb) (2013) 0.88
Role of Phenol-Soluble Modulins in Formation of Staphylococcus aureus Biofilms in Synovial Fluid. Infect Immun (2015) 0.86
Staphylococcus aureus autoinducer-2 quorum sensing decreases biofilm formation in an icaR-dependent manner. BMC Microbiol (2012) 0.82
Temporal and dose-dependent relationships between in vivo B cell receptor-targeted proliferation and deletion-induced by a microbial B cell toxin. J Immunol (2006) 0.82
PSM-Mec-A Virulence Determinant that Connects Transcriptional Regulation, Virulence, and Antibiotic Resistance in Staphylococci. Front Microbiol (2016) 0.80
Host Response to Staphylococcus epidermidis Colonization and Infections. Front Cell Infect Microbiol (2017) 0.79