Published in Science on September 03, 1976
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The histologic border zone of acute myocardial infarction--islands or peninsulas? Am J Pathol (1978) 1.07
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A functional estimate of overlap between adjacent coronary circulations in the dog. Basic Res Cardiol (1986) 0.78
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The cellular production of hydrogen peroxide. Biochem J (1972) 5.25
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Time resolved reflectance and transmittance for the non-invasive measurement of tissue optical properties. Appl Opt (1989) 4.42
Concurrent MRI and diffuse optical tomography of breast after indocyanine green enhancement. Proc Natl Acad Sci U S A (2000) 4.25
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Oxidation-reduction ratio studies of mitochondria in freeze-trapped samples. NADH and flavoprotein fluorescence signals. J Biol Chem (1979) 3.26
Oscillations of glycolytic intermediates in yeast cells. Biochem Biophys Res Commun (1964) 3.22
Azide inhibition of mitochondrial electron transport. I. The aerobic steady state of succinate oxidation. Biochim Biophys Acta (1967) 2.99
Respiratory chain linked H(2)O(2) production in pigeon heart mitochondria. FEBS Lett (1971) 2.93
Validation of near-infrared spectroscopy in humans. J Appl Physiol (1985) (1994) 2.77
Functional intermediates in the reaction of membrane-bound cytochrome oxidase with oxygen. J Biol Chem (1975) 2.68
A mechanism for the reactions of calcium with mitochondria. Proc Natl Acad Sci U S A (1965) 2.54
Flavoproteins of the mitochondrial respiratory chain. Proc Natl Acad Sci U S A (1967) 2.40
The Properties of the Enzyme-Substrate Compounds of Horse-Radish and Lacto-Peroxidase. Science (1949) 2.31
A fluorescence probe of energy-dependent structure changes in fragmented membranes. Proc Natl Acad Sci U S A (1969) 2.22
Fluorescence lifetime imaging in turbid media. Opt Lett (1996) 2.21
Bulk optical properties of healthy female breast tissue. Phys Med Biol (2002) 2.16
Three-dimensional diffuse optical tomography in the parallel plane transmission geometry: evaluation of a hybrid frequency domain/continuous wave clinical system for breast imaging. Med Phys (2003) 2.13
Quantitation of time- and frequency-resolved optical spectra for the determination of tissue oxygenation. Anal Biochem (1991) 2.12
Ketone bodies, potential therapeutic uses. IUBMB Life (2001) 1.98
Sustained sinusoidal oscillations of reduced pyridine nucleotide in a cell-free extract of Saccharomyces carlsbergensis. Proc Natl Acad Sci U S A (1966) 1.98
Insulin, ketone bodies, and mitochondrial energy transduction. FASEB J (1995) 1.95
The relation of free radical production to hyperoxia. Annu Rev Physiol (1986) 1.92
Control of oxidative metabolism and oxygen delivery in human skeletal muscle: a steady-state analysis of the work/energy cost transfer function. Proc Natl Acad Sci U S A (1985) 1.86
Mitochondrial regulation of phosphocreatine/inorganic phosphate ratios in exercising human muscle: a gated 31P NMR study. Proc Natl Acad Sci U S A (1981) 1.85
The role of H 2 O 2 generation in perfused rat liver and the reaction of catalase compound I and hydrogen donors. Arch Biochem Biophys (1973) 1.81
Energy-linked pyridine nucleotide reduction: inhibitory effects of hyperbaric oxygen in vitro and in vivo. Nature (1965) 1.80
Detection of 31P nuclear magnetic resonance signals in brain by in vivo and freeze-trapped assays. Proc Natl Acad Sci U S A (1978) 1.78
Flavin and pyridine nucleotide oxidation-reduction changes in perfused rat liver. I. Anoxia and subcellular localization of fluorescent flavoproteins. J Biol Chem (1969) 1.73
Hydrophilic cyanine dyes as contrast agents for near-infrared tumor imaging: synthesis, photophysical properties and spectroscopic in vivo characterization. Photochem Photobiol (2000) 1.69
Probing physiology and molecular function using optical imaging: applications to breast cancer. Breast Cancer Res (2000) 1.69
Low temperature trapping method for cytochrome oxidase oxygen intermediates. Anal Biochem (1975) 1.68
Reaction of oxygen with the respiratory chain in cells and tissues. J Gen Physiol (1965) 1.68
A hydrogen ion concentration gradient in a mitochondrial membrane. Nature (1966) 1.67
Near-infrared spectroscopic localization of intracranial hematomas. J Neurosurg (1993) 1.66
Cerebral oxygenation during warming after cardiopulmonary bypass. Crit Care Med (1997) 1.63
Evaluation of energy metabolism in skeletal muscle of patients with heart failure with gated phosphorus-31 nuclear magnetic resonance. Circulation (1985) 1.63
The characteristics of the "peroxidatic" reaction of catalase in ethanol oxidation. Biochem J (1973) 1.62
Flavoproteins of mitochondrial fatty acid oxidation. Proc Natl Acad Sci U S A (1967) 1.59
Influence of blood vessels on the measurement of hemoglobin oxygenation as determined by time-resolved reflectance spectroscopy. Med Phys (1995) 1.57
Phosphorus nuclear magnetic resonance studies on normoxic and ischemic cardiac tissue. Proc Natl Acad Sci U S A (1976) 1.57
Contribution of the mitochondrial compartment to the optical properties of the rat liver: a theoretical and practical approach. Biophys J (1994) 1.57
A re-evaluation of the spectral, potentiometric and energy-linked properties of cytochrome c oxidase in mitochondria. FEBS Lett (1976) 1.56
An oxidative defect in metabolic myopathies: diagnosis by noninvasive tissue oximetry. Ann Neurol (1994) 1.56
A versatile time-sharing multichannel spectrophotometer, reflectometer, and fluorometer. Anal Biochem (1975) 1.54
The behavior of oxonol dyes in phospholipid dispersions. Biophys J (1979) 1.53
31P NMR study of improvement in oxidative phosphorylation by vitamins K3 and C in a patient with a defect in electron transport at complex III in skeletal muscle. Proc Natl Acad Sci U S A (1984) 1.53
Hydrogen ion concentration changes in mitochondrial membranes. J Biol Chem (1966) 1.52
Non-invasive and quantitative near-infrared haemoglobin spectrometry in the piglet brain during hypoxic stress, using a frequency-domain multidistance instrument. Phys Med Biol (2001) 1.50
Noninvasive measures of oxidative metabolism on working human muscles by near-infrared spectroscopy. J Appl Physiol (1985) (1996) 1.50
Scattering of diffuse photon density waves by spherical inhomogeneities within turbid media: analytic solution and applications. Proc Natl Acad Sci U S A (1994) 1.49
Kinetics and mechanisms of catalase in peroxisomes of the mitochondrial fraction. Biochem J (1971) 1.49
Noninvasive, nondestructive approaches to cell bioenergetics. Proc Natl Acad Sci U S A (1980) 1.49
Oxidative phosphorylation system during steady-state hypoxia in the dog brain. J Appl Physiol (1985) (1990) 1.48
Control and conservation of energy in the cytochrome chain. Fed Proc (1967) 1.48
Functional intermediates in reaction of cytochrome oxidase with oxygen. Proc Natl Acad Sci U S A (1975) 1.48
Oxidation-reduction properties of the mitochondrial flavoprotein chain. Biochem Biophys Res Commun (1968) 1.47
Abnormal skeletal muscle bioenergetics during exercise in patients with heart failure: role of reduced muscle blood flow. Circulation (1986) 1.46
Fluctuations in cerebral oxygenation and blood volume during endotracheal suctioning in premature infants. J Pediatr (1992) 1.46
Multiple controls of oxidative metabolism in living tissues as studied by phosphorus magnetic resonance. Proc Natl Acad Sci U S A (1986) 1.46
Three-dimensional diffuse optical mammography with ultrasound localization in a human subject. J Biomed Opt (2000) 1.45
Picosecond kinetics of the 1250 nm band of the Rps. sphaeroides reaction center: the nature of the primary photochemical intermediary state. FEBS Lett (1975) 1.45
The steady state level of catalase compound I in isolated hemoglobin-free perfused rat liver. FEBS Lett (1970) 1.45
Mitochondrial responses to carbon monoxide toxicity. Ann N Y Acad Sci (1970) 1.45
Heterogeneity of the hypoxic state in perfused rat heart. Circ Res (1977) 1.44
Experimental images of heterogeneous turbid media by frequency-domain diffusing-photon tomography. Opt Lett (1995) 1.44
Partial resolution of the enzymes catalyzing oxidative phosphorylation. XV. Reverse electron transfer in the flavin-cytochrome beta region of the respiratory chain of beef heart submitochondrial particles. J Biol Chem (1967) 1.42
DPNH oscillations in a cell-free extract of S. carlsbergensis. Biochem Biophys Res Commun (1964) 1.41
Depletion and repletion of Ca2+ in the perfused rat liver. J Lab Clin Med (1992) 1.40
A blinded comparison of noninvasive, in vivo phosphorus nuclear magnetic resonance spectroscopy and the in vitro halothane/caffeine contracture test in the evaluation of malignant hyperthermia susceptibility. Anesth Analg (1991) 1.39
Low Temperature Fluorescence Imaging of Freeze-trapped Human Cervical Tissues. Opt Express (2001) 1.38
Calcium and pyridine nucleotide interaction in mitochondrial membranes. Arch Biochem Biophys (1972) 1.37
Organ chemiluminescence: noninvasive assay for oxidative radical reactions. Proc Natl Acad Sci U S A (1980) 1.36
Rapid ATP assays in perfused mouse liver by 31P NMR. Proc Natl Acad Sci U S A (1979) 1.36
Spectrophotometric measurements of the kinetics of Ca2+ and Mn2+ accumulation in mitochondria. Biochemistry (1968) 1.35
High and low energy states of cytochromes. I. In mitochondria. J Biol Chem (1966) 1.35
Structural features and the reaction mechanism of cytochrome oxidase: iron and copper X-ray absorption fine structure. Biophys J (1981) 1.34
Fluorimetric technique for monitoring changes in the level of reduced nicotinamide nucleotides in continuous cultures of microorganisms. Appl Microbiol (1970) 1.34
Relation of phosphorylation to electron transport in isolated chloroplasts. Brookhaven Symp Biol (1966) 1.33
Low-temperature kinetics of the reaction of oxygen and solubilized cytochrome oxidase. Biochem J (1978) 1.32
Intramitochondrial pH changes in cation accumulation. Proc Natl Acad Sci U S A (1966) 1.31
Kinetics of mitochondrial flavoprotein and pyridine nucleotide in perfused heart. Am J Physiol (1972) 1.29
The compartment syndrome. An experimental and clinical study of muscular energy metabolism using phosphorus nuclear magnetic resonance spectroscopy. Clin Orthop Relat Res (1988) 1.29
Peroxide removal by selenium-dependent and selenium-independent glutathione peroxidases in hemoglobin-free perfused rat liver. J Biol Chem (1978) 1.29
Elucidation of the mode of binding of oxygen to iron in oxyhemoglobin by in frared spectroscopy. Biochem Biophys Res Commun (1973) 1.28
Optimizing tourniquet application and release times in extremity surgery. A biochemical and ultrastructural study. J Bone Joint Surg Am (1985) 1.27
Low temperature photo-induced reactions in green leaves and chloroplasts. Biochim Biophys Acta (1971) 1.27
Fluorescent probe analysis of the lipid architecture of natural and experimental cholesterol-rich membranes. Biochemistry (1974) 1.26
Flow flash kinetics of the cytochrome a 3 -oxygen reaction in coupled and uncoupled mitochondria using the liquid dye laser. Arch Biochem Biophys (1971) 1.26
Intracellular oxidation-reduction state measured in situ by a multichannel fiber-optic surface fluorometer. Science (1982) 1.25
Metabolic coupling and synchronization of NADH oscillations in yeast cell populations. Arch Biochem Biophys (1971) 1.25
Low temperature kinetics of H+ changes of bacterial rhodopsin. Biophys J (1975) 1.25
Determination of optical properties and blood oxygenation in tissue using continuous NIR light. Phys Med Biol (1995) 1.25
The nature of the copper atoms of cytochrome c oxidase as studied by optical and x-ray absorption edge spectroscopy. Biochim Biophys Acta (1979) 1.24
High spatial resolution readout of 3-D metabolic organ structure: an automated, low-temperature redox ratio-scanning instrument. Anal Biochem (1985) 1.24