Published in Proc Natl Acad Sci U S A on October 01, 1978
Studies of acidosis in the ischaemic heart by phosphorus nuclear magnetic resonance. Biochem J (1979) 3.01
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Cerebral metabolic studies in vivo by 31P NMR. Proc Natl Acad Sci U S A (1983) 1.69
Detection of cerebral lactate in vivo during hypoxemia by 1H NMR at relatively low field strengths (1.9 T). Proc Natl Acad Sci U S A (1984) 1.51
Noninvasive, nondestructive approaches to cell bioenergetics. Proc Natl Acad Sci U S A (1980) 1.49
Rapid ATP assays in perfused mouse liver by 31P NMR. Proc Natl Acad Sci U S A (1979) 1.36
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Analysis of rat heart in vivo by phosphorus nuclear magnetic resonance. Proc Natl Acad Sci U S A (1980) 1.20
31P NMR studies of control of mitochondrial function in phosphofructokinase-deficient human skeletal muscle. Proc Natl Acad Sci U S A (1982) 1.18
In vivo carbon-13 nuclear magnetic resonance studies of heart metabolism. Proc Natl Acad Sci U S A (1983) 1.15
31P-n.m.r. studies on cerebral energy metabolism under conditions of hypoglycaemia and hypoxia in vitro. Biochem J (1983) 1.13
31P NMR spectroscopy of rat organs, in situ, using chronically implanted radiofrequency coils. Proc Natl Acad Sci U S A (1983) 1.09
Measurement of changes in high-energy phosphates in the cardiac cycle using gated 31P nuclear magnetic renonance. Proc Natl Acad Sci U S A (1980) 1.08
Physiological concentrations of inorganic phosphate affect MgATP-dependent Ca2+ storage and inositol trisphosphate-induced Ca2+ efflux in microsomal vesicles from non-hepatic cells. Biochem J (1993) 0.99
In vivo 31P NMR study of the metabolism of murine mammary 16/C adenocarcinoma and its response to chemotherapy, x-radiation, and hyperthermia. Proc Natl Acad Sci U S A (1983) 0.97
Non-destructive measurement of metabolites and tissue pH in the kidney by 31P nuclear magnetic resonance. Br J Exp Pathol (1979) 0.90
Brain intracellular pH and metabolism during hypercapnia and hypocapnia in the new-born lamb. J Physiol (1987) 0.78
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Analysis of phosphate metabolites, the intracellular pH, and the state of adenosine triphosphate in intact muscle by phosphorus nuclear magnetic resonance. J Biol Chem (1976) 3.02
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High resolution 31P nuclear magnetic resonance studies of intact yeast cells. Proc Natl Acad Sci U S A (1975) 2.72
Pulsed NMR studies of water in striated muscle. I. Transverse nuclear spin relaxation times and freezing effects. Biochim Biophys Acta (1972) 2.10
Phosphorus NMR studies on perfused heart. Biochem Biophys Res Commun (1977) 2.04
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The state of water in muscle as studied by pulsed NMR. Biochim Biophys Acta (1974) 1.76
Pulsed NMR measurements of the diffusion constant of water in muscle. Arch Biochem Biophys (1971) 1.76
Phosphorus nuclear magnetic resonance studies on normoxic and ischemic cardiac tissue. Proc Natl Acad Sci U S A (1976) 1.57
Influence of complete ischemia on glycolytic metabolites, citric acid cycle intermediates, and associated amino acids in the rat cerebral cortex. Brain Res (1974) 1.41
Effects of membrane depolarization on light scattering by cerebral cortical slices. J Physiol (1973) 1.11
Pulsed NMR studies of water in striated muscle. II. Spin-lattice relaxation times and the dynamics of non-freezing fraction of water. Biochim Biophys Acta (1973) 0.95
A mechanical device for the rapid removal and freezing of liver or brain tissue from unanaesthetized and nonparalyzed rats. Anal Biochem (1975) 0.84
Assessment of outcome after severe brain damage. Lancet (1975) 27.39
Hydroperoxide metabolism in mammalian organs. Physiol Rev (1979) 14.13
Two mRNAs can be produced from a single immunoglobulin mu gene by alternative RNA processing pathways. Cell (1980) 9.86
Perfusion imaging. Magn Reson Med (1992) 7.40
The mitochondrial generation of hydrogen peroxide. General properties and effect of hyperbaric oxygen. Biochem J (1973) 7.01
Magnetic resonance imaging of perfusion using spin inversion of arterial water. Proc Natl Acad Sci U S A (1992) 6.83
Two mRNAs with different 3' ends encode membrane-bound and secreted forms of immunoglobulin mu chain. Cell (1980) 6.32
H2O2 release from human granulocytes during phagocytosis. I. Documentation, quantitation, and some regulating factors. J Clin Invest (1975) 5.90
A national evaluation of specialists' clinics in primary care settings. Br J Gen Pract (2001) 5.28
The cellular production of hydrogen peroxide. Biochem J (1972) 5.25
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Risk adjustment of the postoperative mortality rate for the comparative assessment of the quality of surgical care: results of the National Veterans Affairs Surgical Risk Study. J Am Coll Surg (1997) 4.55
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Concurrent MRI and diffuse optical tomography of breast after indocyanine green enhancement. Proc Natl Acad Sci U S A (2000) 4.25
A Study of the Variations in the Chemical Composition of Normal Human Colostrum and Early Milk. Biochem J (1927) 3.72
A study of the composition of human milk in the later periods of lactation and a comparison with that of early milk. Biochem J (1930) 3.65
Characteristics of isolated and purified preparations of the outer and inner membranes of mitochondria. Ann N Y Acad Sci (1966) 3.64
Studies of photosynthesis using a pulsed laser. I. Temperature dependence of cytochrome oxidation rate in chromatium. Evidence for tunneling. Biophys J (1966) 3.59
Risk adjustment of the postoperative morbidity rate for the comparative assessment of the quality of surgical care: results of the National Veterans Affairs Surgical Risk Study. J Am Coll Surg (1997) 3.46
Oxidation-reduction ratio studies of mitochondria in freeze-trapped samples. NADH and flavoprotein fluorescence signals. J Biol Chem (1979) 3.26
Oscillations of glycolytic intermediates in yeast cells. Biochem Biophys Res Commun (1964) 3.22
Comparison of time-resolved and -unresolved measurements of deoxyhemoglobin in brain. Proc Natl Acad Sci U S A (1988) 3.01
Azide inhibition of mitochondrial electron transport. I. The aerobic steady state of succinate oxidation. Biochim Biophys Acta (1967) 2.99
Respiratory chain linked H(2)O(2) production in pigeon heart mitochondria. FEBS Lett (1971) 2.93
Selective serotonin reuptake inhibitors: meta-analysis of discontinuation rates. Int Clin Psychopharmacol (1994) 2.92
Inositol trisphosphate-induced calcium release and contraction in vascular smooth muscle. Proc Natl Acad Sci U S A (1985) 2.89
A study of the antenatal secretion of the human mammary gland and a comparison between this and the secretion obtained directly after birth. Biochem J (1935) 2.89
Validation of near-infrared spectroscopy in humans. J Appl Physiol (1985) (1994) 2.77
Functional intermediates in the reaction of membrane-bound cytochrome oxidase with oxygen. J Biol Chem (1975) 2.68
Proteoglycan-induced changes in T1rho-relaxation of articular cartilage at 4T. Magn Reson Med (2001) 2.65
A mechanism for the reactions of calcium with mitochondria. Proc Natl Acad Sci U S A (1965) 2.54
Flavoproteins of the mitochondrial respiratory chain. Proc Natl Acad Sci U S A (1967) 2.40
The Properties of the Enzyme-Substrate Compounds of Horse-Radish and Lacto-Peroxidase. Science (1949) 2.31
T1rho-relaxation in articular cartilage: effects of enzymatic degradation. Magn Reson Med (1997) 2.30
Picosecond kinetics of events leading to reaction center bacteriochlorophyll oxidation. Science (1975) 2.30
Short Form 36 (SF-36) Health Survey questionnaire: which normative data should be used? Comparisons between the norms provided by the Omnibus Survey in Britain, the Health Survey for England and the Oxford Healthy Life Survey. J Public Health Med (1999) 2.29
Islets-activating protein (IAP) in Bordetella pertussis that potentiates insulin secretory responses of rats. Purification and characterization. J Biochem (1978) 2.26
A fluorescence probe of energy-dependent structure changes in fragmented membranes. Proc Natl Acad Sci U S A (1969) 2.22
Calcium content of mitochondria and endoplasmic reticulum in liver frozen rapidly in vivo. Nature (1985) 2.21
Fluorescence lifetime imaging in turbid media. Opt Lett (1996) 2.21
Heavy metal tolerance in the fission yeast requires an ATP-binding cassette-type vacuolar membrane transporter. EMBO J (1992) 2.19
Bulk optical properties of healthy female breast tissue. Phys Med Biol (2002) 2.16
Myoglobin O2 desaturation during exercise. Evidence of limited O2 transport. J Clin Invest (1995) 2.14
Three-dimensional diffuse optical tomography in the parallel plane transmission geometry: evaluation of a hybrid frequency domain/continuous wave clinical system for breast imaging. Med Phys (2003) 2.13
Infection with Pseudomonas cepacia in chronic granulomatous disease: role of nonoxidative killing by neutrophils in host defense. J Infect Dis (1994) 2.12
Quantitation of time- and frequency-resolved optical spectra for the determination of tissue oxygenation. Anal Biochem (1991) 2.12
Evaluation of specialists' outreach clinics in general practice in England: process and acceptability to patients, specialists, and general practitioners. J Epidemiol Community Health (1997) 2.10
Water magnetic relaxation dispersion in biological systems: the contribution of proton exchange and implications for the noninvasive detection of cartilage degradation. Proc Natl Acad Sci U S A (2001) 2.07
Decreased SLIM1 expression and increased gelsolin expression in failing human hearts measured by high-density oligonucleotide arrays. Circulation (2000) 2.04
Perfusion imaging with compensation for asymmetric magnetization transfer effects. Magn Reson Med (1996) 2.03
Dilated cardiomyopathy in homozygous myosin-binding protein-C mutant mice. J Clin Invest (1999) 2.02
Sustained sinusoidal oscillations of reduced pyridine nucleotide in a cell-free extract of Saccharomyces carlsbergensis. Proc Natl Acad Sci U S A (1966) 1.98
Ketone bodies, potential therapeutic uses. IUBMB Life (2001) 1.98
Relation of surgical volume to outcome in eight common operations: results from the VA National Surgical Quality Improvement Program. Ann Surg (1999) 1.98
Insulin, ketone bodies, and mitochondrial energy transduction. FASEB J (1995) 1.95
Electromagnetic properties of hemoproteins. V. Optical and electron paramagnetic resonance characteristics of nitric oxide derivatives of metalloporphyrin-apohemoprotein complexes. J Biol Chem (1972) 1.94
The relation of free radical production to hyperoxia. Annu Rev Physiol (1986) 1.92
Probe directed at a segment of Rickettsia rickettsii rRNA amplified with polymerase chain reaction. J Clin Microbiol (1989) 1.91
Release and recycling of calcium by the sarcoplasmic reticulum in guinea-pig portal vein smooth muscle. J Physiol (1984) 1.88
Control of oxidative metabolism and oxygen delivery in human skeletal muscle: a steady-state analysis of the work/energy cost transfer function. Proc Natl Acad Sci U S A (1985) 1.86
Satisfying solutions? A review of some unresolved issues in the measurement of patient satisfaction. J Adv Nurs (1995) 1.85
Mitochondrial regulation of phosphocreatine/inorganic phosphate ratios in exercising human muscle: a gated 31P NMR study. Proc Natl Acad Sci U S A (1981) 1.85
Tissue specific perfusion imaging using arterial spin labeling. NMR Biomed (1994) 1.82
Sodium MRI of human articular cartilage in vivo. Magn Reson Med (1998) 1.82
The role of H 2 O 2 generation in perfused rat liver and the reaction of catalase compound I and hydrogen donors. Arch Biochem Biophys (1973) 1.81
Energy-linked pyridine nucleotide reduction: inhibitory effects of hyperbaric oxygen in vitro and in vivo. Nature (1965) 1.80
Investigation of the increased incidence of gonorrhoea diagnosed in genitourinary medicine clinics in England, 1994-6. Sex Transm Infect (2000) 1.78
Ischemic areas in perfused rat hearts: measurement by NADH fluorescence photography. Science (1976) 1.78
Reduced oxidative muscle metabolism in chronic fatigue syndrome. Muscle Nerve (1996) 1.73
Increased carotid intima-media thickness in children-adolescents, and young adults with a parental history of premature myocardial infarction. Eur Heart J (2002) 1.73
Flavin and pyridine nucleotide oxidation-reduction changes in perfused rat liver. I. Anoxia and subcellular localization of fluorescent flavoproteins. J Biol Chem (1969) 1.73
Hydrophilic cyanine dyes as contrast agents for near-infrared tumor imaging: synthesis, photophysical properties and spectroscopic in vivo characterization. Photochem Photobiol (2000) 1.69
Probing physiology and molecular function using optical imaging: applications to breast cancer. Breast Cancer Res (2000) 1.69
Lymphocytosis of gamma/delta T cells in human ehrlichiosis. Am J Clin Pathol (1995) 1.68
Low temperature trapping method for cytochrome oxidase oxygen intermediates. Anal Biochem (1975) 1.68
Reaction of oxygen with the respiratory chain in cells and tissues. J Gen Physiol (1965) 1.68
A hydrogen ion concentration gradient in a mitochondrial membrane. Nature (1966) 1.67
Equity in access to exercise tolerance testing, coronary angiography, and coronary artery bypass grafting by age, sex and clinical indications. Heart (2001) 1.66
Near-infrared spectroscopic localization of intracranial hematomas. J Neurosurg (1993) 1.66
Relationships between in vivo and in vitro measurements of metabolism in young and old human calf muscles. J Appl Physiol (1985) (1993) 1.66
Cross-bridge kinetics, cooperativity, and negatively strained cross-bridges in vertebrate smooth muscle. A laser-flash photolysis study. J Gen Physiol (1988) 1.64
MR imaging contrast enhancement based on intermolecular zero quantum coherences. Science (1998) 1.64
Selective thermocoagulation of unresectable pancreatic cancers by using radiofrequency capacitive heating. Pancreas (2000) 1.64
Cerebral oxygenation during warming after cardiopulmonary bypass. Crit Care Med (1997) 1.63
Evaluation of energy metabolism in skeletal muscle of patients with heart failure with gated phosphorus-31 nuclear magnetic resonance. Circulation (1985) 1.63
The characteristics of the "peroxidatic" reaction of catalase in ethanol oxidation. Biochem J (1973) 1.62
Comparison of surgical outcomes between teaching and nonteaching hospitals in the Department of Veterans Affairs. Ann Surg (2001) 1.61
Flavoproteins of mitochondrial fatty acid oxidation. Proc Natl Acad Sci U S A (1967) 1.59
Influence of blood vessels on the measurement of hemoglobin oxygenation as determined by time-resolved reflectance spectroscopy. Med Phys (1995) 1.57
Phosphorus nuclear magnetic resonance studies on normoxic and ischemic cardiac tissue. Proc Natl Acad Sci U S A (1976) 1.57
Contribution of the mitochondrial compartment to the optical properties of the rat liver: a theoretical and practical approach. Biophys J (1994) 1.57
An oxidative defect in metabolic myopathies: diagnosis by noninvasive tissue oximetry. Ann Neurol (1994) 1.56
A re-evaluation of the spectral, potentiometric and energy-linked properties of cytochrome c oxidase in mitochondria. FEBS Lett (1976) 1.56
A versatile time-sharing multichannel spectrophotometer, reflectometer, and fluorometer. Anal Biochem (1975) 1.54
Review of wheat improvement for waterlogging tolerance in Australia and India: the importance of anaerobiosis and element toxicities associated with different soils. Ann Bot (2008) 1.53