Published in Carcinogenesis on January 12, 2008
Genetic variation in microRNA networks: the implications for cancer research. Nat Rev Cancer (2010) 7.39
Inflammation and cancer: interweaving microRNA, free radical, cytokine and p53 pathways. Carcinogenesis (2009) 3.40
MicroRNAs in colorectal cancer: translation of molecular biology into clinical application. Mol Cancer (2009) 2.45
MicroRNA polymorphisms: the future of pharmacogenomics, molecular epidemiology and individualized medicine. Pharmacogenomics (2009) 1.88
MicroRNAs and their role in progressive kidney diseases. Clin J Am Soc Nephrol (2009) 1.77
Rare BRCA1 haplotypes including 3'UTR SNPs associated with breast cancer risk. Cell Cycle (2011) 1.64
A risk variant in an miR-125b binding site in BMPR1B is associated with breast cancer pathogenesis. Cancer Res (2009) 1.64
Patrocles: a database of polymorphic miRNA-mediated gene regulation in vertebrates. Nucleic Acids Res (2009) 1.60
Genetic variants in selected pre-microRNA genes and the risk of squamous cell carcinoma of the head and neck. Cancer (2010) 1.45
The role of microRNAs in colorectal cancer. Cancer J (2012) 1.44
MicroRNA and colorectal cancer. World J Surg (2009) 1.40
Identification of colorectal cancer related genes with mRMR and shortest path in protein-protein interaction network. PLoS One (2012) 1.34
A genetic variant in miR-196a2 increased digestive system cancer risks: a meta-analysis of 15 case-control studies. PLoS One (2012) 1.32
MicroRNAs: molecular features and role in cancer. Front Biosci (Landmark Ed) (2012) 1.32
Analyzing illumina gene expression microarray data from different tissues: methodological aspects of data analysis in the metaxpress consortium. PLoS One (2012) 1.31
MicroRNAs: tools for cancer diagnostics. Gut (2009) 1.25
Determinants of incomplete penetrance and variable expressivity in heritable cardiac arrhythmia syndromes. Transl Res (2012) 1.25
A functional variant at the miR-184 binding site in TNFAIP2 and risk of squamous cell carcinoma of the head and neck. Carcinogenesis (2011) 1.22
MicroRNA dysregulation in colorectal cancer: a clinical perspective. Br J Cancer (2011) 1.20
The impact of microRNAs on colorectal cancer. Virchows Arch (2009) 1.20
Alterations of microRNAs contribute to colon carcinogenesis. Semin Oncol (2011) 1.19
The role of microRNA-binding site polymorphisms in DNA repair genes as risk factors for bladder cancer and breast cancer and their impact on radiotherapy outcomes. Carcinogenesis (2011) 1.17
Complete characterization of the microRNAome in a patient with acute myeloid leukemia. Blood (2010) 1.16
Identification of a functional SNP in the 3'UTR of CXCR2 that is associated with reduced risk of lung cancer. Cancer Res (2014) 1.14
Genetic polymorphisms in pre-microRNA genes as prognostic markers of colorectal cancer. Cancer Epidemiol Biomarkers Prev (2011) 1.14
Association of germline microRNA SNPs in pre-miRNA flanking region and breast cancer risk and survival: the Carolina Breast Cancer Study. Cancer Causes Control (2013) 1.13
Inferring causative variants in microRNA target sites. Nucleic Acids Res (2011) 1.12
Prognostic impact of microRNA-related gene polymorphisms on survival of patients with colorectal cancer. J Cancer Res Clin Oncol (2010) 1.09
MicroRNA-mediated regulation of gene expression is affected by disease-associated SNPs within the 3'-UTR via altered RNA structure. RNA Biol (2012) 1.08
A miR-570 binding site polymorphism in the B7-H1 gene is associated with the risk of gastric adenocarcinoma. Hum Genet (2013) 1.08
Genome-wide association study identifies four genetic loci associated with thyroid volume and goiter risk. Am J Hum Genet (2011) 1.07
Comprehensive analysis of the impact of SNPs and CNVs on human microRNAs and their regulatory genes. RNA Biol (2009) 1.07
MicroRNA binding site polymorphisms as biomarkers of cancer risk. Expert Rev Mol Diagn (2010) 1.06
Mechanisms and role of microRNA deregulation in cancer onset and progression. Genet Mol Biol (2011) 1.02
rs4919510 in hsa-mir-608 is associated with outcome but not risk of colorectal cancer. PLoS One (2012) 0.98
NOD2 expression is regulated by microRNAs in colonic epithelial HCT116 cells. Inflamm Bowel Dis (2014) 0.98
MicroRNA polymorphisms: a giant leap towards personalized medicine. Per Med (2009) 0.93
Early detection of colorectal cancer: from conventional methods to novel biomarkers. J Cancer Res Clin Oncol (2015) 0.92
MicroRNA binding site polymorphisms as biomarkers in cancer management and research. Pharmgenomics Pers Med (2014) 0.91
A let-7 microRNA-binding site polymorphism in KRAS predicts improved outcome in patients with metastatic colorectal cancer treated with salvage cetuximab/panitumumab monotherapy. Clin Cancer Res (2014) 0.88
The role of microRNAs in cancer susceptibility. Biomed Res Int (2013) 0.87
MiRNAs and LincRNAs: Could they be considered as biomarkers in colorectal cancer? Int J Mol Sci (2012) 0.87
Single Nucleotide Polymorphisms Associated with MicroRNA Regulation. Biomolecules (2013) 0.87
The miR-184 binding-site rs8126 T>C polymorphism in TNFAIP2 is associated with risk of gastric cancer. PLoS One (2013) 0.87
A polymorphism at the miR-502 binding site in the 3' untranslated region of the SET8 gene is associated with the outcome of small-cell lung cancer. Exp Ther Med (2012) 0.87
Effects of common polymorphism rs11614913 in Hsa-miR-196a2 on lung cancer risk. PLoS One (2013) 0.87
SNPs in microRNA binding sites as prognostic and predictive cancer biomarkers. Crit Rev Oncog (2013) 0.86
Computational and experimental approaches to reveal the effects of single nucleotide polymorphisms with respect to disease diagnostics. Int J Mol Sci (2014) 0.86
miRNAs in precancerous lesions of the gastrointestinal tract. World J Gastroenterol (2011) 0.86
miR-485-5p binding site SNP rs8752 in HPGD gene is associated with breast cancer risk. PLoS One (2014) 0.86
Development and progression of colorectal neoplasia. Cancer Biomark (2010) 0.85
MicroRNA related polymorphisms and breast cancer risk. PLoS One (2014) 0.85
MicroRNA-9 and microRNA-326 regulate human dopamine D2 receptor expression, and the microRNA-mediated expression regulation is altered by a genetic variant. J Biol Chem (2014) 0.85
How microRNAs influence both hereditary and inflammatory-mediated colon cancers. Cancer Genet (2013) 0.83
Common genetic variants in miR-1206 (8q24.2) and miR-612 (11q13.3) affect biogenesis of mature miRNA forms. PLoS One (2012) 0.83
The involvement of Kras gene 3'-UTR polymorphisms in risk of cancer and influence on patient response to anti-EGFR therapy in metastatic colorectal cancer: a meta-analysis. Onco Targets Ther (2014) 0.83
Mechanistic insights into the role of microRNAs in cancer: influence of nutrient crosstalk. Front Genet (2012) 0.83
miRNAs as biomarkers for management of patients with colorectal cancer. Biomark Med (2010) 0.83
microRNA Regulation and Its Consequences in Cancer. Curr Pathobiol Rep (2012) 0.82
Single-nucleotide polymorphisms of microRNA processing machinery genes and risk of colorectal cancer. Onco Targets Ther (2015) 0.81
Demonstrating polymorphic miRNA-mediated gene regulation in vivo: application to the g+6223G->A mutation of Texel sheep. RNA (2010) 0.80
Prognostic significance of microRNA gene polymorphisms in patients with surgically resected colorectal cancer. Exp Ther Med (2011) 0.80
Identification of novel sequence variations in microRNAs in chronic lymphocytic leukemia. Carcinogenesis (2013) 0.79
MicroRNA polymorphisms and risk of colorectal cancer. Cancer Epidemiol Biomarkers Prev (2014) 0.79
A Study on Genetic Association of Interleukin-16 Single Nucleotide Polymorphism (rs1131445) With Chronic Hepatitis B Virus Infection in Iranian Patients. Jundishapur J Microbiol (2015) 0.79
Single-nucleotide polymorphisms among microRNA: big effects on cancer. Chin J Cancer (2011) 0.79
Genetic variants in microRNA target sites of 37 selected cancer-related genes and the risk of cervical cancer. PLoS One (2014) 0.79
Association of co-stimulatory human B-lymphocyte antigen B7-2 (CD86) gene polymorphism with colorectal cancer risk. Gastroenterol Hepatol Bed Bench (2013) 0.77
A variant at a potentially functional microRNA-binding site in BRIP1 was associated with risk of squamous cell carcinoma of the head and neck. Tumour Biol (2015) 0.77
miR-502 medaited histone methyltransferase SET8 expression is associated with outcome of esophageal squamous cell carcinoma. Sci Rep (2016) 0.77
Association between polymorphisms in the integrin gene predicted microRNA binding sites and bladder cancer risk. Int J Clin Exp Med (2014) 0.77
The Associations between RNA Splicing Complex Gene SF3A1 Polymorphisms and Colorectal Cancer Risk in a Chinese Population. PLoS One (2015) 0.77
A genetic variation in microRNA target site of ETS2 is associated with clinical outcomes of paclitaxel-cisplatin chemotherapy in non-small cell lung cancer. Oncotarget (2016) 0.77
Genome-wide identification of microRNA-related variants associated with risk of Alzheimer's disease. Sci Rep (2016) 0.77
SNP Regulation of microRNA Expression and Subsequent Colon Cancer Risk. PLoS One (2015) 0.76
MicroRNA-related polymorphisms and non-Hodgkin lymphoma susceptibility in the Multicenter AIDS Cohort Study. Cancer Epidemiol (2016) 0.76
A functional single nucleotide polymorphism of SET8 is prognostic for breast cancer. Oncotarget (2016) 0.76
Polymorphisms in MicroRNA Binding Sites Predict Colorectal Cancer Survival. Int J Med Sci (2017) 0.75
Validation of microRNA pathway polymorphisms in esophageal adenocarcinoma survival. Cancer Med (2017) 0.75
SNPs in microRNA target sites and their potential role in human disease. Open Biol (2017) 0.75
Distinct role of CD86 polymorphisms (rs1129055, rs17281995) in risk of cancer: evidence from a meta-analysis. PLoS One (2014) 0.75
Genetic variant rs16430 6bp > 0bp at the microRNA-binding site in TYMS and risk of sporadic breast cancer risk in non-Hispanic white women aged ≤ 55 years. Mol Carcinog (2013) 0.75
MiR-339 and especially miR-766 reactivate the expression of tumor suppressor genes in colorectal cancer cell lines through DNA methyltransferase 3B gene inhibition. Cancer Biol Ther (2016) 0.75
A GDF15 3' UTR variant, rs1054564, results in allele-specific translational repression of GDF15 by hsa-miR-1233-3p. PLoS One (2017) 0.75
Polymorphism (rs16917496) at the miR-502 Binding Site of the Lysine Methyltransferase 5A (SET8) and Its Correlation with Colorectal Cancer in Iranians. Adv Biomed Res (2017) 0.75
E2F1 somatic mutation within miRNA target site impairs gene regulation in colorectal cancer. PLoS One (2017) 0.75
TERT promoter mutations in familial and sporadic melanoma. Science (2013) 7.82
Genome-wide association study identifies five susceptibility loci for glioma. Nat Genet (2009) 7.62
Sequence variants at the TERT-CLPTM1L locus associate with many cancer types. Nat Genet (2009) 6.91
Genome-wide association scan identifies a colorectal cancer susceptibility locus on 11q23 and replicates risk loci at 8q24 and 18q21. Nat Genet (2008) 6.75
A genome-wide association study identifies colorectal cancer susceptibility loci on chromosomes 10p14 and 8q23.3. Nat Genet (2008) 6.26
Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array. Nat Genet (2013) 5.58
Genome-wide association study identifies variants in the ABO locus associated with susceptibility to pancreatic cancer. Nat Genet (2009) 5.14
A locus on 19p13 modifies risk of breast cancer in BRCA1 mutation carriers and is associated with hormone receptor-negative breast cancer in the general population. Nat Genet (2010) 4.96
A genome-wide association study identifies pancreatic cancer susceptibility loci on chromosomes 13q22.1, 1q32.1 and 5p15.33. Nat Genet (2010) 4.89
New common variants affecting susceptibility to basal cell carcinoma. Nat Genet (2009) 4.15
A multi-stage genome-wide association study of bladder cancer identifies multiple susceptibility loci. Nat Genet (2010) 3.93
Genome-wide association studies identify four ER negative-specific breast cancer risk loci. Nat Genet (2013) 3.81
Detectable clonal mosaicism and its relationship to aging and cancer. Nat Genet (2012) 3.69
Environmental and heritable causes of cancer among 9.6 million individuals in the Swedish Family-Cancer Database. Int J Cancer (2002) 3.55
A common variant at the TERT-CLPTM1L locus is associated with estrogen receptor-negative breast cancer. Nat Genet (2011) 3.37
BRAF mutations in metastatic melanoma: a possible association with clinical outcome. Clin Cancer Res (2003) 3.21
Seven prostate cancer susceptibility loci identified by a multi-stage genome-wide association study. Nat Genet (2011) 3.07
Polymorphisms of DNA repair genes and risk of non-small cell lung cancer. Carcinogenesis (2005) 2.50
Variation in CDKN2A at 9p21.3 influences childhood acute lymphoblastic leukemia risk. Nat Genet (2010) 2.47
A germline variant in the TP53 polyadenylation signal confers cancer susceptibility. Nat Genet (2011) 2.43
Systemically delivered antisense oligomers upregulate gene expression in mouse tissues. Nat Biotechnol (2002) 2.38
Molecular allelokaryotyping of pediatric acute lymphoblastic leukemias by high-resolution single nucleotide polymorphism oligonucleotide genomic microarray. Blood (2007) 2.31
Familial risk of cancer shortly after diagnosis of the first familial tumor. J Natl Cancer Inst (2005) 2.23
Association of common polymorphisms in inflammatory genes interleukin (IL)6, IL8, tumor necrosis factor alpha, NFKB1, and peroxisome proliferator-activated receptor gamma with colorectal cancer. Cancer Res (2003) 2.18
Familial renal cell carcinoma from the Swedish Family-Cancer Database. Eur Urol (2011) 2.10
Interactions between genetic variants and breast cancer risk factors in the breast and prostate cancer cohort consortium. J Natl Cancer Inst (2011) 2.09
Familial risk of lymphoproliferative tumors in families of patients with chronic lymphocytic leukemia: results from the Swedish Family-Cancer Database. Blood (2004) 2.05
Mesothelioma is a killer of urban men in Sweden. Int J Cancer (2003) 2.02
Genome-wide association study of classical Hodgkin lymphoma and Epstein-Barr virus status-defined subgroups. J Natl Cancer Inst (2012) 1.99
Autoimmunity and susceptibility to Hodgkin lymphoma: a population-based case-control study in Scandinavia. J Natl Cancer Inst (2006) 1.90
Cigarette smoking and pancreatic cancer: a pooled analysis from the pancreatic cancer cohort consortium. Am J Epidemiol (2009) 1.87
SNPs in ultraconserved elements and familial breast cancer risk. Carcinogenesis (2008) 1.84
Chromosome 7p11.2 (EGFR) variation influences glioma risk. Hum Mol Genet (2011) 1.83
Activating BRAF and N-Ras mutations in sporadic primary melanomas: an inverse association with allelic loss on chromosome 9. Oncogene (2003) 1.82
Pancreatic cancer risk and ABO blood group alleles: results from the pancreatic cancer cohort consortium. Cancer Res (2010) 1.82
TERT promoter mutations in bladder cancer affect patient survival and disease recurrence through modification by a common polymorphism. Proc Natl Acad Sci U S A (2013) 1.82
Obesity and the risk of papillary thyroid cancer: a pooled analysis of three case-control studies. Thyroid (2014) 1.81
Medullary thyroid carcinoma (MTC) and RET proto-oncogene: mutation spectrum in the familial cases and a meta-analysis of studies on the sporadic form. Mutat Res (2012) 1.80
Mammographic screening is dramatically changing age-incidence data for breast cancer. J Clin Oncol (2004) 1.80
Large-scale investigation of base excision repair genetic polymorphisms and lung cancer risk in a multicenter study. J Natl Cancer Inst (2005) 1.79
Polymorphisms in DNA repair and metabolic genes in bladder cancer. Carcinogenesis (2003) 1.78
Fine-mapping identifies multiple prostate cancer risk loci at 5p15, one of which associates with TERT expression. Hum Mol Genet (2013) 1.78
PTPRD (protein tyrosine phosphatase receptor type delta) is associated with restless legs syndrome. Nat Genet (2008) 1.78
Polymorphisms in genes of nucleotide and base excision repair: risk and prognosis of colorectal cancer. Clin Cancer Res (2006) 1.77
Prediagnostic circulating vitamin D levels and risk of hepatocellular carcinoma in European populations: a nested case-control study. Hepatology (2014) 1.75
Ancestry-shift refinement mapping of the C6orf97-ESR1 breast cancer susceptibility locus. PLoS Genet (2010) 1.74
Research recommendations for selected IARC-classified agents. Environ Health Perspect (2010) 1.73
Oxytocin receptor polymorphisms and adult attachment style in patients with depression. Psychoneuroendocrinology (2009) 1.70
SNP microarray analysis for genome-wide detection of crossover regions. Hum Genet (2005) 1.68
Genetic variation in the HSD17B1 gene and risk of prostate cancer. PLoS Genet (2005) 1.67
BRAF and NRAS mutations are frequent in nodular melanoma but are not associated with tumor cell proliferation or patient survival. J Invest Dermatol (2005) 1.66
Vascular endothelial growth factor polymorphisms in relation to breast cancer development and prognosis. Clin Cancer Res (2005) 1.66
Genome-wide association study of survival in patients with pancreatic adenocarcinoma. Gut (2012) 1.66
B-RAF and N-RAS mutations are preserved during short time in vitro propagation and differentially impact prognosis. PLoS One (2007) 1.65
Common breast cancer susceptibility loci are associated with triple-negative breast cancer. Cancer Res (2011) 1.65
Verification of the susceptibility loci on 7p12.2, 10q21.2, and 14q11.2 in precursor B-cell acute lymphoblastic leukemia of childhood. Blood (2009) 1.64
Determining the effectiveness of High Resolution Melting analysis for SNP genotyping and mutation scanning at the TP53 locus. BMC Genet (2009) 1.63
Aberrant DNA methylation of cancer-associated genes in gastric cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC-EURGAST). Cancer Lett (2011) 1.62
Development of a sensitive and specific assay combining multiplex PCR and DNA microarray primer extension to detect high-risk mucosal human papillomavirus types. J Clin Microbiol (2006) 1.61
Second primary cancers in patients with nasopharyngeal carcinoma: a pooled analysis of 13 cancer registries. Cancer Causes Control (2007) 1.61
Familial characteristics of autoimmune and hematologic disorders in 8,406 multiple myeloma patients: a population-based case-control study. Int J Cancer (2006) 1.61
Familial aggregation of Hodgkin lymphoma and related tumors. Cancer (2004) 1.60
Identification of frequent chromosome copy-number polymorphisms by use of high-resolution single-nucleotide-polymorphism arrays. Am J Hum Genet (2006) 1.60
Evidence for an important role of alcohol- and aldehyde-metabolizing genes in cancers of the upper aerodigestive tract. Cancer Epidemiol Biomarkers Prev (2006) 1.59
A catalog of polymorphisms falling in microRNA-binding regions of cancer genes. DNA Cell Biol (2008) 1.58
The 'common disease-common variant' hypothesis and familial risks. PLoS One (2008) 1.56
Inherited predisposition to early onset lung cancer according to histological type. Int J Cancer (2004) 1.56
Second primary cancers in thyroid cancer patients: a multinational record linkage study. J Clin Endocrinol Metab (2006) 1.54
The XPD variant alleles are associated with increased aromatic DNA adduct level and lung cancer risk. Carcinogenesis (2002) 1.53
A comprehensive analysis of phase I and phase II metabolism gene polymorphisms and risk of colorectal cancer. Pharmacogenet Genomics (2005) 1.53
The balance between heritable and environmental aetiology of human disease. Nat Rev Genet (2006) 1.51
Inflammation-related gene polymorphisms and colorectal adenoma. Cancer Epidemiol Biomarkers Prev (2006) 1.51
IGF-1, IGFBP-1, and IGFBP-3 polymorphisms predict circulating IGF levels but not breast cancer risk: findings from the Breast and Prostate Cancer Cohort Consortium (BPC3). PLoS One (2008) 1.50
Autoimmune disease in individuals and close family members and susceptibility to non-Hodgkin's lymphoma. Arthritis Rheum (2008) 1.50
Effect of common B-RAF and N-RAS mutations on global gene expression in melanoma cell lines. Carcinogenesis (2005) 1.48
Cornual pregnancy successfully treated by suction curettage and operative hysteroscopy. BJOG (2003) 1.48
A meta-analysis of genome-wide association studies to identify prostate cancer susceptibility loci associated with aggressive and non-aggressive disease. Hum Mol Genet (2012) 1.47
Multiple melanomas after treatment for Hodgkin lymphoma in a non-Dutch p16-Leiden mutation carrier with 2 MC1R high-risk variants. Arch Dermatol (2007) 1.47
Polymorphisms in predicted microRNA-binding sites in integrin genes and breast cancer: ITGB4 as prognostic marker. Carcinogenesis (2008) 1.45
Familial aggregation and heterogeneity of non-Hodgkin lymphoma in population-based samples. Cancer Epidemiol Biomarkers Prev (2005) 1.45
Variation at 10p12.2 and 10p14 influences risk of childhood B-cell acute lymphoblastic leukemia and phenotype. Blood (2013) 1.45
Evaluation of SNPs in miR-146a, miR196a2 and miR-499 as low-penetrance alleles in German and Italian familial breast cancer cases. Hum Mutat (2010) 1.45