Published in PLoS One on December 07, 2012
Epigenome-wide association study of body mass index, and the adverse outcomes of adiposity. Nature (2016) 1.59
DNA methylation of lipid-related genes affects blood lipid levels. Circ Cardiovasc Genet (2015) 1.12
A meta-analysis of gene expression signatures of blood pressure and hypertension. PLoS Genet (2015) 0.99
Genome-Wide Detection of Gene Coexpression Domains Showing Linkage to Regions Enriched with Polymorphic Retrotransposons in Recombinant Inbred Mouse Strains. G3 (Bethesda) (2013) 0.90
Characterization of whole-genome autosomal differences of DNA methylation between men and women. Epigenetics Chromatin (2015) 0.90
Multi-omic signature of body weight change: results from a population-based cohort study. BMC Med (2015) 0.89
Genetic determinants of circulating interleukin-1 receptor antagonist levels and their association with glycemic traits. Diabetes (2014) 0.86
Mapping the genetic architecture of gene regulation in whole blood. PLoS One (2014) 0.85
Modulation of insulin degrading enzyme activity and liver cell proliferation. Cell Cycle (2015) 0.85
Biomarkers of coronary artery disease: the promise of the transcriptome. Curr Cardiol Rep (2014) 0.84
Tobacco smoking is associated with DNA methylation of diabetes susceptibility genes. Diabetologia (2016) 0.84
The Human Blood Metabolome-Transcriptome Interface. PLoS Genet (2015) 0.82
Re-Annotator: Annotation Pipeline for Microarray Probe Sequences. PLoS One (2015) 0.79
Analysis of the transcriptome in molecular epidemiology studies. Environ Mol Mutagen (2013) 0.79
Molecular Characterization of the NLRC4 Expression in Relation to Interleukin-18 Levels. Circ Cardiovasc Genet (2015) 0.78
Endophenotype Network Models: Common Core of Complex Diseases. Sci Rep (2016) 0.78
Association between DNA Methylation in Whole Blood and Measures of Glucose Metabolism: KORA F4 Study. PLoS One (2016) 0.77
Genomewide meta-analysis identifies loci associated with IGF-I and IGFBP-3 levels with impact on age-related traits. Aging Cell (2016) 0.77
Chemical genomics for studying parasite gene function and interaction. Trends Parasitol (2013) 0.76
Gene transcripts associated with muscle strength: a CHARGE meta-analysis of 7,781 persons. Physiol Genomics (2015) 0.75
Extensive alterations of the whole-blood transcriptome are associated with body mass index: results of an mRNA profiling study involving two large population-based cohorts. BMC Med Genomics (2015) 0.75
Associations between Serum Sex Hormone Concentrations and Whole Blood Gene Expression Profiles in the General Population. PLoS One (2015) 0.75
Microarray multiplex assay for the simultaneous detection and discrimination of influenza a and influenza B viruses. Indian J Microbiol (2013) 0.75
Comparison of pre-processing methods for multiplex bead-based immunoassays. BMC Genomics (2016) 0.75
Blood RNA expression profiles undergo major changes during the seventh decade. Oncotarget (2016) 0.75
Removing Batch Effects from Longitudinal Gene Expression - Quantile Normalization Plus ComBat as Best Approach for Microarray Transcriptome Data. PLoS One (2016) 0.75
Blood cis-eQTL analysis fails to identify novel association signals among sub-threshold candidates from genome-wide association studies in restless legs syndrome. PLoS One (2014) 0.75
The human genome browser at UCSC. Genome Res (2002) 168.23
Gene expression profiling predicts clinical outcome of breast cancer. Nature (2002) 71.36
Minimum information about a microarray experiment (MIAME)-toward standards for microarray data. Nat Genet (2001) 63.36
A gene-expression signature as a predictor of survival in breast cancer. N Engl J Med (2002) 58.15
lumi: a pipeline for processing Illumina microarray. Bioinformatics (2008) 17.19
Gene expression and benefit of chemotherapy in women with node-negative, estrogen receptor-positive breast cancer. J Clin Oncol (2006) 16.25
Breast cancer classification and prognosis based on gene expression profiles from a population-based study. Proc Natl Acad Sci U S A (2003) 13.00
Oncomine 3.0: genes, pathways, and networks in a collection of 18,000 cancer gene expression profiles. Neoplasia (2007) 10.74
Genevestigator v3: a reference expression database for the meta-analysis of transcriptomes. Adv Bioinformatics (2008) 8.36
Outcome signature genes in breast cancer: is there a unique set? Bioinformatics (2004) 7.96
Chemosensitivity prediction by transcriptional profiling. Proc Natl Acad Sci U S A (2001) 7.51
Genetics and beyond--the transcriptome of human monocytes and disease susceptibility. PLoS One (2010) 7.48
The UCSC Genome Browser database: extensions and updates 2011. Nucleic Acids Res (2011) 6.88
RankProd: a bioconductor package for detecting differentially expressed genes in meta-analysis. Bioinformatics (2006) 6.50
Model-based variance-stabilizing transformation for Illumina microarray data. Nucleic Acids Res (2008) 6.15
Predictive ability of DNA microarrays for cancer outcomes and correlates: an empirical assessment. Lancet (2003) 4.58
Cohort profile: the study of health in Pomerania. Int J Epidemiol (2010) 4.38
KORA--a research platform for population based health research. Gesundheitswesen (2005) 3.95
Trans-eQTLs reveal that independent genetic variants associated with a complex phenotype converge on intermediate genes, with a major role for the HLA. PLoS Genet (2011) 3.65
A re-annotation pipeline for Illumina BeadArrays: improving the interpretation of gene expression data. Nucleic Acids Res (2009) 3.50
Key issues in conducting a meta-analysis of gene expression microarray datasets. PLoS Med (2008) 3.31
A trans-acting locus regulates an anti-viral expression network and type 1 diabetes risk. Nature (2010) 2.88
Meta-analysis of clear cell renal cell carcinoma gene expression defines a variant subgroup and identifies gender influences on tumor biology. Eur Urol (2011) 2.55
Unraveling the regulatory mechanisms underlying tissue-dependent genetic variation of gene expression. PLoS Genet (2012) 2.29
Polymorphisms within micro-RNA-binding sites and risk of sporadic colorectal cancer. Carcinogenesis (2008) 2.09
Molecular testing in the management of cardiac transplant recipients: initial clinical experience. J Heart Lung Transplant (2006) 1.84
Incidence of Type 2 diabetes in the elderly German population and the effect of clinical and lifestyle risk factors: KORA S4/F4 cohort study. Diabet Med (2009) 1.82
Meta-analysis and its problems. BMJ (1994) 1.78
Comparison of normalization methods for Illumina BeadChip HumanHT-12 v3. BMC Genomics (2010) 1.50
Comparison study of microarray meta-analysis methods. BMC Bioinformatics (2010) 1.49
A latent variable approach for meta-analysis of gene expression data from multiple microarray experiments. BMC Bioinformatics (2007) 1.48
GEMS (Gene Expression MetaSignatures), a Web resource for querying meta-analysis of expression microarray datasets: 17beta-estradiol in MCF-7 cells. Cancer Res (2009) 1.44
Meta-analysis of gene expression profiles related to relapse-free survival in 1,079 breast cancer patients. Breast Cancer Res Treat (2008) 1.14
Meta-analysis of gene expression profiles associated with histological classification and survival in 829 ovarian cancer samples. Int J Cancer (2011) 1.06
Integrative meta-analysis of differential gene expression in acute myeloid leukemia. PLoS One (2010) 1.03
Distribution and categorization of left ventricular measurements in the general population: results from the population-based Gutenberg Heart Study. Circ Cardiovasc Imaging (2010) 0.98
Predicting drug response based on gene expression. Crit Rev Oncol Hematol (2004) 0.97
Eigen-R2 for dissecting variation in high-dimensional studies. Bioinformatics (2008) 0.97
Meta-analysis of microarray gene expression studies on intracranial aneurysms. Neuroscience (2011) 0.94
Investigation of variation in gene expression profiling of human blood by extended principle component analysis. PLoS One (2011) 0.93
Probe mapping across multiple microarray platforms. Brief Bioinform (2011) 0.89
Sample selection for microarray gene expression studies. Methods Inf Med (2005) 0.84
Statistical Test of Expression Pattern (STEPath): a new strategy to integrate gene expression data with genomic information in individual and meta-analysis studies. BMC Bioinformatics (2011) 0.80
Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes. Nat Genet (2008) 35.06
Biological, clinical and population relevance of 95 loci for blood lipids. Nature (2010) 28.21
Genomewide association analysis of coronary artery disease. N Engl J Med (2007) 24.38
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. Nat Genet (2010) 23.08
Six new loci associated with body mass index highlight a neuronal influence on body weight regulation. Nat Genet (2008) 22.35
Hundreds of variants clustered in genomic loci and biological pathways affect human height. Nature (2010) 20.01
Particulate matter air pollution and cardiovascular disease: An update to the scientific statement from the American Heart Association. Circulation (2010) 19.30
New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk. Nat Genet (2010) 17.89
Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis. Nat Genet (2010) 16.96
Identification of ten loci associated with height highlights new biological pathways in human growth. Nat Genet (2008) 16.25
Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease. Nature (2012) 16.13
Common variants near MC4R are associated with fat mass, weight and risk of obesity. Nat Genet (2008) 15.94
A common genetic variant is associated with adult and childhood obesity. Science (2006) 14.95
Genetic variants regulating ORMDL3 expression contribute to the risk of childhood asthma. Nature (2007) 14.43
Mutations in LRRK2 cause autosomal-dominant parkinsonism with pleomorphic pathology. Neuron (2004) 14.35
Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease. Nat Genet (2011) 13.25
Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. Nature (2011) 13.25
Genome-wide association study identifies eight loci associated with blood pressure. Nat Genet (2009) 12.44
Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts. Nat Genet (2008) 12.32
Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants. Nat Genet (2009) 12.19
Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study. Lancet (2012) 12.10
Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes. Nat Genet (2012) 11.09
Variants in MTNR1B influence fasting glucose levels. Nat Genet (2008) 10.85
Genome-wide association study reveals genetic risk underlying Parkinson's disease. Nat Genet (2009) 10.34
Transcriptome and genome sequencing uncovers functional variation in humans. Nature (2013) 8.89
Meta-analysis and imputation refines the association of 15q25 with smoking quantity. Nat Genet (2010) 8.55
Range of genetic mutations associated with severe non-syndromic sporadic intellectual disability: an exome sequencing study. Lancet (2012) 8.42