PubRank

C C Winterbourn

Author PubWeight™ 143.62‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Inside the neutrophil phagosome: oxidants, myeloperoxidase, and bacterial killing. Blood 1998 5.02
2 The estimation of red cell superoxide dismutase activity. J Lab Clin Med 1975 2.75
3 Comparison of superoxide with other reducing agents in the biological production of hydroxyl radicals. Biochem J 1979 2.26
4 Comparative reactivities of various biological compounds with myeloperoxidase-hydrogen peroxide-chloride, and similarity of the oxidant to hypochlorite. Biochim Biophys Acta 1985 2.15
5 Protein carbonyl measurement by a sensitive ELISA method. Free Radic Biol Med 1997 2.14
6 Involvement of superoxide and myeloperoxidase in oxygen-dependent killing of Staphylococcus aureus by neutrophils. Infect Immun 1996 1.83
7 The ability of scavengers to distinguish OH. production in the iron-catalyzed Haber-Weiss reaction: comparison of four assays for OH. Free Radic Biol Med 1987 1.73
8 A microtiter plate assay for superoxide dismutase using a water-soluble tetrazolium salt (WST-1). Clin Chim Acta 2000 1.73
9 Thiocyanate and chloride as competing substrates for myeloperoxidase. Biochem J 1997 1.70
10 Reactions involving superoxide and normal and unstable haemoglobins. Biochem J 1976 1.66
11 Oxidative reactions of hemoglobin. Methods Enzymol 1990 1.55
12 Production of the superoxide adduct of myeloperoxidase (compound III) by stimulated human neutrophils and its reactivity with hydrogen peroxide and chloride. Biochem J 1985 1.51
13 Kinetics of the reactions of hypochlorous acid and amino acid chloramines with thiols, methionine, and ascorbate. Free Radic Biol Med 2001 1.50
14 Lactoferrin-catalysed hydroxyl radical production. Additional requirement for a chelating agent. Biochem J 1983 1.47
15 Chlorination of tyrosyl residues in peptides by myeloperoxidase and human neutrophils. J Biol Chem 1995 1.45
16 Oxidation of parenteral lipid emulsion by ambient and phototherapy lights: potential toxicity of routine parenteral feeding. J Pediatr 1995 1.45
17 Assays for the chlorination activity of myeloperoxidase. Methods Enzymol 1994 1.45
18 Activated oxygen and haemolysis. Br J Haematol 1975 1.41
19 Studies of hemoglobin denaturation and Heinz body formation in the unstable hemoglobins. J Clin Invest 1974 1.39
20 Oxidative damage to fibronectin. I. The effects of the neutrophil myeloperoxidase system and HOCl. Arch Biochem Biophys 1991 1.33
21 Mechanism of inactivation of myeloperoxidase by 4-aminobenzoic acid hydrazide. Biochem J 1997 1.33
22 Hydroxyl radical production in body fluids. Roles of metal ions, ascorbate and superoxide. Biochem J 1981 1.32
23 Inhibition of myeloperoxidase by benzoic acid hydrazides. Biochem J 1995 1.26
24 A single assay for measuring the rates of phagocytosis and bacterial killing by neutrophils. J Leukoc Biol 1994 1.24
25 Oxidation of human haemoglobin by copper. Mechanism and suggested role of the thiol group of residue beta-93. Biochem J 1977 1.22
26 Superoxide modulates the activity of myeloperoxidase and optimizes the production of hypochlorous acid. Biochem J 1988 1.22
27 Oxidation of intracellular glutathione after exposure of human red blood cells to hypochlorous acid. Biochem J 1995 1.18
28 Living with a killer: the effects of hypochlorous acid on mammalian cells. IUBMB Life 2001 1.17
29 Mechanism of inhibition of myeloperoxidase by anti-inflammatory drugs. Biochem Pharmacol 1991 1.16
30 Cytochrome c reduction by semiquinone radicals can be indirectly inhibited by superoxide dismutase. Arch Biochem Biophys 1981 1.16
31 Methods for quantifying phagocytosis and bacterial killing by human neutrophils. J Immunol Methods 1999 1.14
32 Free-radical production and oxidative reactions of hemoglobin. Environ Health Perspect 1985 1.12
33 The rate of reaction of superoxide radical ion with oxyhaemoglobin and methaemoglobin. Biochem J 1976 1.11
34 Myeloperoxidase as an effective inhibitor of hydroxyl radical production. Implications for the oxidative reactions of neutrophils. J Clin Invest 1986 1.10
35 On the participation of higher oxidation states of iron and copper in Fenton reactions. Free Radic Biol Med 1989 1.10
36 Human neutrophil collagenase cleaves alpha 1-antitrypsin. Biochem J 1990 1.07
37 Production of hydroxyl radicals from paraquat radicals and H2O2. FEBS Lett 1981 1.07
38 Nitrite as a substrate and inhibitor of myeloperoxidase. Implications for nitration and hypochlorous acid production at sites of inflammation. J Biol Chem 2000 1.06
39 Mechanism of oxyhaemoglobin breakdown on reaction with acetylphenylhydrazine. Biochem J 1978 1.06
40 Degradation of glomerular basement membrane by human neutrophils in vitro. Biochim Biophys Acta 1984 1.06
41 Hydroxyl radical production from hydrogen peroxide and enzymatically generated paraquat radicals: catalytic requirements and oxygen dependence. Arch Biochem Biophys 1984 1.05
42 Radical driven Fenton reactions--evidence from paraquat radical studies for production of tetravalent iron in the presence and absence of ethylenediaminetetraacetic acid. Arch Biochem Biophys 1987 1.03
43 Influence of superoxide on myeloperoxidase kinetics measured with a hydrogen peroxide electrode. Biochem J 1989 1.03
44 The effect of oxidants on neutrophil-mediated degradation of glomerular basement membrane collagen. Biochim Biophys Acta 1986 1.03
45 Superoxide dismutase as an inhibitor of reactions of semiquinone radicals. FEBS Lett 1978 1.02
46 Superoxide is an antagonist of antiinflammatory drugs that inhibit hypochlorous acid production by myeloperoxidase. Biochem Pharmacol 1993 1.02
47 Modification of neutrophil oxidant production with diphenyleneiodonium and its effect on bacterial killing. Free Radic Biol Med 1995 1.02
48 Inhibition of neutrophil degranulation and superoxide production by sulfasalazine. Comparison with 5-aminosalicylic acid, sulfapyridine and olsalazine. Biochem Pharmacol 1987 1.01
49 Hypochlorous acid stimulation of the mitogen-activated protein kinase pathway enhances cell survival. Arch Biochem Biophys 2001 1.01
50 A genetically engineered mutant of alpha 1-antitrypsin protects connective tissue from neutrophil damage and may be useful in lung disease. Lancet 1984 0.98
51 Peroxynitrite and myeloperoxidase leave the same footprint in protein nitration. Redox Rep 1998 0.98
52 Low density lipoprotein peptide metabolism in nephrotic syndrome: a comparison with patterns observed in other syndromes characterised by hyperlipoproteinaemia. Australas Ann Med 1970 0.98
53 The mechanism of myeloperoxidase-dependent chlorination of monochlorodimedon. Biochim Biophys Acta 1988 0.98
54 Neutrophils adherent to a nonphagocytosable surface (glomerular basement membrane) produce oxidants only at the site of attachment. Blood 1985 0.98
55 Bacterial killing by neutrophils in hypertonic environments. J Infect Dis 1994 0.98
56 Assays using horseradish peroxidase and phenolic substrates require superoxide dismutase for accurate determination of hydrogen peroxide production by neutrophils. Free Radic Biol Med 1994 0.98
57 Loss of GSH and thiol enzymes in endothelial cells exposed to sublethal concentrations of hypochlorous acid. Am J Physiol 1999 0.96
58 Early ascorbic acid depletion is related to the severity of acute pancreatitis. Br J Surg 1999 0.95
59 Elevated protein carbonyls and lipid peroxidation products correlating with myeloperoxidase in tracheal aspirates from premature infants. Pediatr Res 2000 0.95
60 Generation of superoxide and tyrosine peroxide as a result of tyrosyl radical scavenging by glutathione. Arch Biochem Biophys 1995 0.94
61 Glutathione oxidation by hypochlorous acid in endothelial cells produces glutathione sulfonamide as a major product but not glutathione disulfide. J Biol Chem 2001 0.94
62 Vitamin C is reduced in human milk after storage. Acta Paediatr 2001 0.93
63 The correlation of elevated levels of an index of lipid peroxidation (MDA-TBA) with adverse outcome in the very low birthweight infant. Acta Paediatr 1996 0.93
64 Superoxide-dependent hydroxylation by myeloperoxidase. J Biol Chem 1994 0.92
65 A kinetic analysis of the catalase activity of myeloperoxidase. Biochemistry 2001 0.92
66 Chlorination of cholesterol in cell membranes by hypochlorous acid. Arch Biochem Biophys 1996 0.91
67 Vitamin C supplementation in very preterm infants: a randomised controlled trial. Arch Dis Child Fetal Neonatal Ed 2005 0.91
68 Membrane changes associated with lysis of red blood cells by hypochlorous acid. Free Radic Biol Med 1994 0.91
69 Doxorubicin-dependent lipid peroxidation at low partial pressures of O2. J Free Radic Biol Med 1985 0.90
70 Oxidation of neutrophil glutathione and protein thiols by myeloperoxidase-derived hypochlorous acid. Biochem J 1997 0.90
71 Hypochlorous acid-mediated modification of cholesterol and phospholipid: analysis of reaction products by gas chromatography-mass spectrometry. J Lipid Res 1993 0.90
72 Gelatinase contributes to the degradation of glomerular basement membrane collagen by human neutrophils. Coll Relat Res 1988 0.89
73 Low-density lipoprotein accumulation in actively growing xanthomas. J Atheroscler Res 1967 0.89
74 Superoxide enhances hypochlorous acid production by stimulated human neutrophils. Biochim Biophys Acta 1990 0.89
75 A pulse radiolysis investigation of the reactions of myeloperoxidase with superoxide and hydrogen peroxide. Biochim Biophys Acta 1988 0.89
76 Myeloperoxidase-dependent oxidative inactivation of neutrophil neutral proteinases and microbicidal enzymes. Biochem J 1987 0.89
77 Modification of red cell membrane lipids by hypochlorous acid and haemolysis by preformed lipid chlorohydrins. Redox Rep 1998 0.89
78 Different effects of hypochlorous acid on human neutrophil metalloproteinases: activation of collagenase and inactivation of collagenase and gelatinase. Arch Biochem Biophys 1992 0.88
79 Cleavage and inactivation of alpha 1-antitrypsin by metalloproteinases released from neutrophils. J Clin Invest 1988 0.88
80 The reaction of menadione with haemoglobin. Mechanism and effect of superoxide dismutase. Biochem J 1979 0.87
81 Limiting light-induced lipid peroxidation and vitamin loss in infant parenteral nutrition by adding multivitamin preparations to Intralipid. Acta Paediatr 2001 0.87
82 The attachment of Heinz bodies to the red cell membrane. Br J Haematol 1973 0.86
83 Iron and xanthine oxidase catalyze formation of an oxidant species distinguishable from OH.: comparison with the Haber-Weiss reaction. Arch Biochem Biophys 1986 0.86
84 Deoxyribose breakdown by the adriamycin semiquinone and H2O2: evidence for hydroxyl radical participation. FEBS Lett 1982 0.85
85 Reactions of Adriamycin with haemoglobin. Superoxide dismutase indirectly inhibits reactions of the Adriamycin semiquinone. Biochem J 1982 0.85
86 The superoxide-dependent transfer of iron from ferritin to transferrin and lactoferrin. Biochem J 1988 0.84
87 Selenium and glutathione peroxidase levels in premature infants in a low selenium community (Christchurch, New Zealand). Pediatr Res 1992 0.84
88 Proteinase-antiproteinase balance in tracheal aspirates from neonates. Eur Respir J 1994 0.84
89 Inhibition by nonsteroidal anti-inflammatory drugs of superoxide production and granule enzyme release by polymorphonuclear leukocytes stimulated with immune complexes or formyl-methionyl-leucyl-phenylalanine. Biochem Pharmacol 1987 0.84
90 6-Hydroxydopamine releases iron from ferritin and promotes ferritin-dependent lipid peroxidation. Biochem Pharmacol 1989 0.84
91 Plasma vitamin A levels in the very low birthweight infant--relationship to respiratory outcome. Early Hum Dev 1998 0.83
92 Chelated iron-catalyzed OH. formation from paraquat radicals and H2O2: mechanism of formate oxidation. Arch Biochem Biophys 1984 0.83
93 Reduced glutathione in combination with superoxide dismutase as an important biological antioxidant defence mechanism. Biochem Pharmacol 1989 0.83
94 The relationship of selenium status to respiratory outcome in the very low birth weight infant. Pediatrics 1995 0.83
95 Oxidative interactions between haemoglobin and membrane lipid. A liposome model. Biochem J 1984 0.83
96 Activation of human neutrophil gelatinase by endogenous serine proteinases. Biochem J 1988 0.83
97 Contributions of superoxide, hydrogen peroxide, and transition metal ions to auto-oxidation of the favism-inducing pyrimidine aglycone, divicine, and its reactions with haemoglobin. Biochem Pharmacol 1986 0.82
98 The hydrolysis product of ICRF-187 promotes iron-catalysed hydroxyl radical production via the Fenton reaction. Biochem Pharmacol 1993 0.82
99 Peroxidase-mediated bromination of unsaturated fatty acids to form bromohydrins. Arch Biochem Biophys 1996 0.82
100 The uptake of plasma fatty acids into human red cells and its relationship to cell age. Biochim Biophys Acta 1970 0.82
101 dl-N,N'-dicarboxamidomethyl-N,N'-dicarboxymethyl-1,2-diaminopropane (ICRF-198) and d-1,2-bis(3,5-dioxopiperazine-1-yl)propane (ICRF-187) inhibition of Fe3+ reduction, lipid peroxidation, and CaATPase inactivation in heart microsomes exposed to adriamycin. Cancer Res 1990 0.81
102 Oxidative metabolism of amsacrine by the neutrophil enzyme myeloperoxidase. Biochem Pharmacol 1992 0.81
103 Lipid composition of human red cells of different ages. Biochim Biophys Acta 1970 0.81
104 Release of iron from phagocytosed Escherichia coli and uptake by neutrophil lactoferrin. Blood 1990 0.81
105 Comparison of mono- and dichlorinated tyrosines with carbonyls for detection of hypochlorous acid modified proteins. Arch Biochem Biophys 2000 0.81
106 Characterization of Heinz bodies in unstable haemoglobin haemolytic anaemia. Nature 1972 0.81
107 Radical-driven Fenton reactions: studies with paraquat, adriamycin, and anthraquinone 6-sulfonate and citrate, ATP, ADP, and pyrophosphate iron chelates. Arch Biochem Biophys 1987 0.80
108 Pharmacologic levels of heparin do not destabilize neonatal parenteral nutrition. JPEN J Parenter Enteral Nutr 1998 0.80
109 Protection by ascorbate against acetylphenylhydrazine-induced Heinz body formation in glucose-6-phosphate dehydrogenase deficient erythrocytes. Br J Haematol 1979 0.80
110 Oxidation of hydroquinone by myeloperoxidase. Mechanism of stimulation by benzoquinone. J Biol Chem 1992 0.80
111 High-affinity iron binding by xanthine oxidase. J Free Radic Biol Med 1986 0.79
112 Release of iron from ferritin by semiquinone, anthracycline, bipyridyl, and nitroaromatic radicals. Free Radic Biol Med 1989 0.79
113 Free radical inactivation of rabbit muscle creatinine kinase: catalysis by physiological and hydrolyzed ICRF-187 (ICRF-198) iron chelates. Free Radic Res 1995 0.79
114 Superoxide dismutase (glu100-->gly) in a family with inherited motor neuron disease: detection of mutant superoxide dismutase activity and the presence of heterodimers. Neurosci Lett 1995 0.79
115 Lipid peroxide and hydrogen peroxide formation in parenteral nutrition solutions containing multivitamins. JPEN J Parenter Enteral Nutr 2001 0.79
116 Haemoglobin denaturation, lipid peroxidation and haemolysis in phenylhydrazine-induced anaemia. Biochim Biophys Acta 1984 0.79
117 High plasma thiocyanate levels are associated with enhanced myeloperoxidase-induced thiol oxidation and long-term survival in subjects following a first myocardial infarction. Free Radic Res 2014 0.78
118 Vitamin A and E status in very low birth weight infants: development of an improved parenteral delivery system. J Pediatr 1995 0.78
119 Selenium status of Christchurch infants and the effect of diet. N Z Med J 1992 0.78
120 Iron binding to microsomes and liposomes in relation to lipid peroxidation. FEBS Lett 1987 0.78
121 Oxidative damage to fibronectin. II. The effect of H2O2 and the hydroxyl radical. Arch Biochem Biophys 1991 0.78
122 Free-radical production from acetylphenylhydrazine and haemoglobin [proceedings]. Biochem Soc Trans 1977 0.78
123 Changes in ascorbate levels on stimulation of human neutrophils. Biochim Biophys Acta 1983 0.78
124 Haemoglobin North Shore, beta134 Val replaced by Glu, a new unstable haemoglobin. Biochim Biophys Acta 1977 0.77
125 Differential reactivities of hypochlorous and hypobromous acids with purified Escherichia coli phospholipid: formation of haloamines and halohydrins. Biochim Biophys Acta 1998 0.77
126 The effect of selenium supplementation on outcome in very low birth weight infants: a randomized controlled trial. The New Zealand Neonatal Study Group. J Pediatr 2000 0.77
127 Inhibition of adriamycin-promoted microsomal lipid peroxidation by beta-carotene, alpha-tocopherol and retinol at high and low oxygen partial pressures. FEBS Lett 1988 0.77
128 Microsomal lipid peroxidation induced by adriamycin, epirubicin, daunorubicin and mitoxantrone: a comparative study. Cancer Chemother Pharmacol 1989 0.77
129 Superoxide dismutase-inhibitible reduction of cytochrome c by the alloxan radical. Implications for alloxan cytotoxicity. Biochem J 1982 0.77
130 Oxidative hemoglobin breakdown induced by a rubber additive. Hemoglobin 1981 0.76
131 Activation of NF-kappaB in human neutrophils during phagocytosis of bacteria independently of oxidant generation. FEBS Lett 1998 0.76
132 The reaction of hemoglobin with paraquat radicals in the presence and absence of O2. Biochem Int 1983 0.76
133 Cleavage of alpha 1-antitrypsin by human neutrophil collagenase. Matrix Suppl 1992 0.76
134 Microsomal reduction of low-molecular-weight Fe3+ chelates and ferritin: enhancement by adriamycin, paraquat, menadione, and anthraquinone 2-sulfonate and inhibition by oxygen. Arch Biochem Biophys 1988 0.76
135 Association of hydrogen peroxide in exhaled breath condensates from infants with respiratory distress syndrome with the development of chronic lung disease. Arch Dis Child Fetal Neonatal Ed 2006 0.76
136 Adriamycin-dependent peroxidation of rat liver and heart microsomes catalysed by iron chelates and ferritin. Maximum peroxidation at low oxygen partial pressures. Biochem Pharmacol 1988 0.76
137 Small bowel ischaemia-reperfusion increases plasma concentrations of oxidised proteins in rats. Eur J Surg 1999 0.76
138 Tetravalent vanadium releases ferritin iron which stimulates vanadium-dependent lipid peroxidation. Free Radic Res Commun 1991 0.75
139 Selenium status of New Zealand infants fed either a selenium supplemented or a standard formula. J Paediatr Child Health 1995 0.75
140 Haemoglobin oxidation and free radical production in the red cell. Biomed Biochim Acta 1983 0.75
141 Metabolism in vivo of bovine erythrocyte lipids. Biochim Biophys Acta 1968 0.75
142 Brain lipids of mice homozygous for the gene 'dilute lethal' (d). J Neurochem 1971 0.75
143 Release of iron from ferritin by divicine, isouramil, acid-hydrolyzed vicine, and dialuric acid and initiation of lipid peroxidation. Arch Biochem Biophys 1989 0.75
144 Role of the gut in synthesizing the protein component of low-density (beta) lipoprotein. Nature 1965 0.75
145 The destabilisation of total parenteral nutrition by heparin. How real is the problem? N Z Med J 1997 0.75
146 Hexose monophosphate shunt-stimulated reduction of methemoglobin by divicine. Arch Biochem Biophys 1985 0.75
147 Nuclear magnetic resonance characterization of 6 alpha-chloro-5 beta-cholestane-3 beta,5-diol formed from the reaction of hypochlorous acid with cholesterol. Lipids 1997 0.75
148 The influence of superoxide on the production of hypochlorous acid by human neutrophils. Free Radic Res Commun 1991 0.75
149 Inhibition of neutrophil-mediated degradation of isolated basement membrane collagen by nonsteroidal antiinflammatory drugs that inhibit degranulation. Arthritis Rheum 1987 0.75
150 Unstable haemoglobin haemolytic crises: contributions of pyrexia and neutrophil oxidants. Br J Haematol 1981 0.75
151 The unstable hemoglobins. Tex Rep Biol Med 1982 0.75
152 Hemoglobin autoxidation: the risk of the red cell and the contribution of copper. Prog Clin Biol Res 1978 0.75
153 Hemoglobin oxidation and inter-relationship with lipid peroxidation in the red cell. Prog Clin Biol Res 1985 0.75
154 Plasma antioxidants and protection against alpha-1-proteinase inhibitor inactivation. Am Rev Respir Dis 1987 0.75
155 Haemoglobin--a frustrated oxidase? Implications for red cell metabolism. Hemoglobin 1977 0.75
156 Dietary selenium. N Z Med J 1992 0.75
157 Effect of oral administration of ascorbate on acetylphenylhydrazine-induced Heinz body formation. Br J Haematol 1980 0.75
158 An iron chelator is not required for reductive iron release from ferritin by radical generating systems. Free Radic Res Commun 1989 0.75
159 Separation of brain gangliosides by column chromatography on DEAE-cellulose. J Neurochem 1971 0.75
160 Reactivity of the beta-93 SH groups in Hb Köln. Hemoglobin 1977 0.75
161 The absence of lipid peroxidation in human red cells exposed to acetylphenylhydrazine. Br J Haematol 1972 0.75
162 Oxidative inactivation of neutrophil granule proteinases: implications for neutrophil-mediated proteolysis. Basic Life Sci 1988 0.75
163 Isolation of high oxygen affinity hemoglobins. Hemoglobin 1977 0.75
164 Incorporation of [I-14C]palmitate into the lipids of bovine blood cells. Biochim Biophys Acta 1968 0.75
165 Rapid proteolysis of unstable globins in human bone marrow. Br J Haematol 1983 0.75
166 Endotracheal suctioning of the neonate: comparison of two methods as a source of mucus material for research. Pediatr Pulmonol 1997 0.75