Published in Malar J on January 24, 2008
Identification and analysis of putative homologues of mechanosensitive channels in pathogenic protozoa. PLoS One (2013) 0.92
Identification and functional analysis of the primary pantothenate transporter, PfPAT, of the human malaria parasite Plasmodium falciparum. J Biol Chem (2013) 0.92
Identification of putative potassium channel homologues in pathogenic protozoa. PLoS One (2012) 0.85
A Trk/HKT-type K+ transporter from Trypanosoma brucei. Eukaryot Cell (2010) 0.84
Phylogenetic profiles of all membrane transport proteins. Microb Cell (2016) 0.75
Functional characterization of malaria parasites deficient in the K(+) channel Kch2. Biochem Biophys Res Commun (2017) 0.75
Human malaria parasites in continuous culture. Science (1976) 59.70
Synchronization of Plasmodium falciparum erythrocytic stages in culture. J Parasitol (1979) 23.90
The transcriptome of the intraerythrocytic developmental cycle of Plasmodium falciparum. PLoS Biol (2003) 11.86
Targeting malaria virulence and remodeling proteins to the host erythrocyte. Science (2004) 7.01
Chloroquine resistance in Plasmodium falciparum malaria parasites conferred by pfcrt mutations. Science (2002) 6.19
A host-targeting signal in virulence proteins reveals a secretome in malarial infection. Science (2004) 6.16
Invasion of red blood cells by malaria parasites. Cell (2006) 5.94
Apical membrane antigen 1 plays a central role in erythrocyte invasion by Plasmodium species. Mol Microbiol (2000) 3.70
Global analysis of transcript and protein levels across the Plasmodium falciparum life cycle. Genome Res (2004) 3.63
The Plasmodium falciparum sexual development transcriptome: a microarray analysis using ontology-based pattern identification. Mol Biochem Parasitol (2005) 3.02
Cycloguanil and its parent compound proguanil demonstrate distinct activities against Plasmodium falciparum malaria parasites transformed with human dihydrofolate reductase. Mol Pharmacol (1998) 2.50
Membrane transport in the malaria-infected erythrocyte. Physiol Rev (2001) 2.10
A critical role for PfCRT K76T in Plasmodium falciparum verapamil-reversible chloroquine resistance. EMBO J (2005) 2.09
Co-ordinated programme of gene expression during asexual intraerythrocytic development of the human malaria parasite Plasmodium falciparum revealed by microarray analysis. Mol Microbiol (2001) 1.96
The malaria-infected red blood cell: structural and functional changes. Adv Parasitol (2001) 1.91
The 'permeome' of the malaria parasite: an overview of the membrane transport proteins of Plasmodium falciparum. Genome Biol (2005) 1.91
Intracellular calcium stores in Toxoplasma gondii govern invasion of host cells. J Cell Sci (2003) 1.87
Toxoplasma gondii microneme secretion involves intracellular Ca(2+) release from inositol 1,4,5-triphosphate (IP(3))/ryanodine-sensitive stores. J Biol Chem (2002) 1.70
Cooperative domains define a unique host cell-targeting signal in Plasmodium falciparum-infected erythrocytes. Proc Natl Acad Sci U S A (2003) 1.53
Tetracycline analogue-regulated transgene expression in Plasmodium falciparum blood stages using Toxoplasma gondii transactivators. Proc Natl Acad Sci U S A (2005) 1.49
Chloroquine resistance modulated in vitro by expression levels of the Plasmodium falciparum chloroquine resistance transporter. J Biol Chem (2003) 1.48
Induction and localization of Plasmodium falciparum stress proteins related to the heat shock protein 70 family. Mol Biochem Parasitol (1991) 1.42
The membrane potential of the intraerythrocytic malaria parasite Plasmodium falciparum. J Biol Chem (2003) 1.36
Trypsin inhibitor paradoxically stabilizes trypsin activity in sodium dodecyl sulfate, facilitating proteolytic fingerprinting. Anal Biochem (1991) 0.97
Defining the minimal domain of the Plasmodium falciparum protein MESA involved in the interaction with the red cell membrane skeletal protein 4.1. J Biol Chem (1997) 0.95
Potassium channel structures: do they conform? Curr Opin Struct Biol (2004) 0.92
Biophysical and pharmacological aspects of K+ channels in T lymphocytes. Eur Biophys J (2005) 0.90
Molecular cloning of a K(+) channel from the malaria parasite Plasmodium falciparum. Biochem Biophys Res Commun (2004) 0.89
Channels and transporters as drug targets in the Plasmodium-infected erythrocyte. Acta Trop (2004) 0.89
Functional analysis of Plasmodium falciparum merozoite antigens: implications for erythrocyte invasion and vaccine development. Philos Trans R Soc Lond B Biol Sci (2002) 0.89
Urea reduces the aggregation of membrane proteins on sodium dodecyl sulfate-polyacrylamide gel electrophoresis. Anal Biochem (1996) 0.86
Bright and stable near-infrared fluorescent protein for in vivo imaging. Nat Biotechnol (2011) 4.14
Pharmacological rescue of synaptic plasticity, courtship behavior, and mushroom body defects in a Drosophila model of fragile X syndrome. Neuron (2005) 4.11
Dysregulation of mTOR signaling in fragile X syndrome. J Neurosci (2010) 3.73
KCNE1 binds to the KCNQ1 pore to regulate potassium channel activity. Neuron (2004) 2.07
Epigenomic modifications predict active promoters and gene structure in Toxoplasma gondii. PLoS Pathog (2007) 1.69
Microarray analysis of global changes in gene expression during cardiac myocyte differentiation. Physiol Genomics (2002) 1.68
Attenuated Plasmodium yoelii lacking purine nucleoside phosphorylase confer protective immunity. Nat Med (2008) 1.65
An analytical pipeline for genomic representations used for cytosine methylation studies. Bioinformatics (2008) 1.64
Post-translational modifications to Toxoplasma gondii alpha- and beta-tubulins include novel C-terminal methylation. J Proteome Res (2010) 1.64
A single transmembrane site in the KCNE-encoded proteins controls the specificity of KvLQT1 channel gating. J Biol Chem (2002) 1.48
Distinct mechanisms govern proteolytic shedding of a key invasion protein in apicomplexan pathogens. Mol Microbiol (2005) 1.45
CaT1 contributes to the stores-operated calcium current in Jurkat T-lymphocytes. J Biol Chem (2002) 1.39
Targeting a novel Plasmodium falciparum purine recycling pathway with specific immucillins. J Biol Chem (2004) 1.34
14-3-3 amplifies and prolongs adrenergic stimulation of HERG K+ channel activity. EMBO J (2002) 1.30
Noninvasive real-time monitoring of liver-stage development of bioluminescent Plasmodium parasites. J Infect Dis (2009) 1.28
Energetic mapping of transition state analogue interactions with human and Plasmodium falciparum purine nucleoside phosphorylases. J Biol Chem (2005) 1.28
Plasmodium falciparum purine nucleoside phosphorylase: crystal structures, immucillin inhibitors, and dual catalytic function. J Biol Chem (2004) 1.26
Transition state analogue inhibitors of purine nucleoside phosphorylase from Plasmodium falciparum. J Biol Chem (2001) 1.25
The Toxoplasma gondii rhoptry protein ROP4 is secreted into the parasitophorous vacuole and becomes phosphorylated in infected cells. Eukaryot Cell (2004) 1.25
Molecular analysis of PIP2 regulation of HERG and IKr. Am J Physiol Heart Circ Physiol (2004) 1.24
An LQT mutant minK alters KvLQT1 trafficking. Am J Physiol Cell Physiol (2004) 1.24
Purine-less death in Plasmodium falciparum induced by immucillin-H, a transition state analogue of purine nucleoside phosphorylase. J Biol Chem (2001) 1.24
Voltage-gated potassium channels: regulation by accessory subunits. Neuroscientist (2006) 1.23
KCNE regulation of KvLQT1 channels: structure-function correlates. Trends Cardiovasc Med (2002) 1.20
TgSUB2 is a Toxoplasma gondii rhoptry organelle processing proteinase. Mol Microbiol (2003) 1.19
Pharmacological reversal of synaptic plasticity deficits in the mouse model of fragile X syndrome by group II mGluR antagonist or lithium treatment. Brain Res (2010) 1.14
Improved transfection and new selectable markers for the rodent malaria parasite Plasmodium yoelii. Mol Biochem Parasitol (2006) 1.14
Toxoplasma gondii sequesters centromeres to a specific nuclear region throughout the cell cycle. Proc Natl Acad Sci U S A (2011) 1.14
Computational analysis and experimental validation of gene predictions in Toxoplasma gondii. PLoS One (2008) 1.08
Toxoplasma gondii and Cryptosporidium parvum lack detectable DNA cytosine methylation. Eukaryot Cell (2008) 1.03
Identification and characterisation of a regulatory region in the Toxoplasma gondii hsp70 genomic locus. Int J Parasitol (2004) 1.03
PTEN promoter methylation and activation of the PI3K/Akt/mTOR pathway in pediatric gliomas and influence on clinical outcome. Neuro Oncol (2012) 1.03
Functional interactions between KCNE1 C-terminus and the KCNQ1 channel. PLoS One (2009) 1.03
Toxoplasma gondii protease TgSUB1 is required for cell surface processing of micronemal adhesive complexes and efficient adhesion of tachyzoites. Cell Microbiol (2010) 1.01
Plasmodium falciparum purine nucleoside phosphorylase is critical for viability of malaria parasites. J Biol Chem (2008) 1.01
The Toxoplasma nuclear factor TgAP2XI-4 controls bradyzoite gene expression and cyst formation. Mol Microbiol (2012) 1.01
Location, location, location: trafficking and function of secreted proteases of Toxoplasma and Plasmodium. Traffic (2004) 1.00
Proteolytic processing of the Cryptosporidium glycoprotein gp40/15 by human furin and by a parasite-derived furin-like protease activity. Infect Immun (2006) 1.00
Proton radiation therapy for pediatric medulloblastoma and supratentorial primitive neuroectodermal tumors: outcomes for very young children treated with upfront chemotherapy. Int J Radiat Oncol Biol Phys (2013) 1.00
Comprehensive proteomic analysis of membrane proteins in Toxoplasma gondii. Mol Cell Proteomics (2010) 1.00
PKA phosphorylation of HERG protein regulates the rate of channel synthesis. Am J Physiol Heart Circ Physiol (2009) 0.99
Cyclic nucleotide kinases and tachyzoite-bradyzoite transition in Toxoplasma gondii. Int J Parasitol (2005) 0.99
Differential association between HERG and KCNE1 or KCNE2. PLoS One (2007) 0.98
Phosphatidylinositol 4,5-bisphosphate interactions with the HERG K(+) channel. Pflugers Arch (2007) 0.97
EPIC-DB: a proteomics database for studying Apicomplexan organisms. BMC Genomics (2009) 0.96
A function for tyrosine phosphorylation of type 1 inositol 1,4,5-trisphosphate receptor in lymphocyte activation. J Cell Biol (2007) 0.96
The prodomain of Toxoplasma gondii GPI-anchored subtilase TgSUB1 mediates its targeting to micronemes. Traffic (2008) 0.95
Structural and metabolic specificity of methylthiocoformycin for malarial adenosine deaminases. Biochemistry (2009) 0.95
Cyclin-dependent kinase TPK2 is a critical cell cycle regulator in Toxoplasma gondii. Mol Microbiol (2002) 0.94
High mobility group protein HMGB2 is a critical regulator of plasmodium oocyst development. J Biol Chem (2008) 0.94
Analysis of the interactions between the C-terminal cytoplasmic domains of KCNQ1 and KCNE1 channel subunits. Biochem J (2010) 0.94
Plasmodium protease ROM1 is important for proper formation of the parasitophorous vacuole. PLoS Pathog (2011) 0.93
Pore mutants of HERG and KvLQT1 downregulate the reciprocal currents in stable cell lines. Am J Physiol Heart Circ Physiol (2010) 0.93
The histone code of Toxoplasma gondii comprises conserved and unique posttranslational modifications. MBio (2013) 0.93
Chromatin modifications, epigenetics, and how protozoan parasites regulate their lives. Trends Parasitol (2012) 0.93
The Impact of HIV and Malaria Coinfection: What Is Known and Suggested Venues for Further Study. Interdiscip Perspect Infect Dis (2009) 0.92
Age-dependent cognitive impairment in a Drosophila fragile X model and its pharmacological rescue. Biogerontology (2009) 0.91
Toxoplasma gondii purine nucleoside phosphorylase biochemical characterization, inhibitor profiles, and comparison with the Plasmodium falciparum ortholog. J Biol Chem (2006) 0.90
Analysis of the glycoproteome of Toxoplasma gondii using lectin affinity chromatography and tandem mass spectrometry. Microbes Infect (2011) 0.90
Effect of dietary p-aminobenzoic acid on murine Plasmodium yoelii infection. J Infect Dis (2003) 0.90
Plasmodium falciparum: growth response to potassium channel blocking compounds. Exp Parasitol (2008) 0.90
Toxoplasma gondii proteomics. Expert Rev Proteomics (2009) 0.89
Toxoplasma transcription factor TgAP2XI-5 regulates the expression of genes involved in parasite virulence and host invasion. J Biol Chem (2013) 0.89
Stable expression of Cryptosporidium parvum glycoprotein gp40/15 in Toxoplasma gondii. Mol Biochem Parasitol (2007) 0.88
A homolog of FHM2 is involved in modulation of excitatory neurotransmission by serotonin in C. elegans. PLoS One (2010) 0.88
Role of CpSUB1, a subtilisin-like protease, in Cryptosporidium parvum infection in vitro. Eukaryot Cell (2009) 0.88
Imaging devices for use in small animals. Semin Nucl Med (2011) 0.87
HIV in the tropics: staging in the resource-limited setting. Curr Opin Infect Dis (2012) 0.87
Functional characterization of a putative aquaporin from Encephalitozoon cuniculi, a microsporidia pathogenic to humans. Int J Parasitol (2005) 0.87
Discovery of a splicing regulator required for cell cycle progression. PLoS Genet (2013) 0.86
S641 contributes HERG K+ channel inactivation. Cell Biochem Biophys (2004) 0.85
Proton radiotherapy for solid tumors of childhood. Technol Cancer Res Treat (2012) 0.85
Protein kinase A activity at the endoplasmic reticulum surface is responsible for augmentation of human ether-a-go-go-related gene product (HERG). J Biol Chem (2011) 0.85
Stimulation of N-terminal truncated isoform of androgen receptor stabilizes human ether-á-go-go-related gene-encoded potassium channel protein via activation of extracellular signal regulated kinase 1/2. Endocrinology (2008) 0.85
A-kinase anchoring protein targeting of protein kinase A and regulation of HERG channels. J Membr Biol (2008) 0.85
A nucleolar AAA-NTPase is required for parasite division. Mol Microbiol (2013) 0.83
The unfolded protein response in the protozoan parasite Toxoplasma gondii features translational and transcriptional control. Eukaryot Cell (2013) 0.83
Motivation to pursue genetic testing in individuals with a personal or family history of cardiac events or sudden cardiac death. J Genet Couns (2014) 0.83
Improved techniques for endogenous epitope tagging and gene deletion in Toxoplasma gondii. J Microbiol Methods (2011) 0.82
How epigenomics contributes to the understanding of gene regulation in Toxoplasma gondii. J Eukaryot Microbiol (2009) 0.82
Pharmacological and genetic reversal of age-dependent cognitive deficits attributable to decreased presenilin function. J Neurosci (2010) 0.82
Compton scattering by internal shields based on melanin-containing mushrooms provides protection of gastrointestinal tract from ionizing radiation. Cancer Biother Radiopharm (2012) 0.81
New eukaryotic systematics: a phylogenetic perspective of developmental gene expression in the Apicomplexa. Int J Parasitol (2008) 0.81
Post-transcriptional control of human ether-a-go-go-related gene potassium channel protein by alpha-adrenergic receptor stimulation. Mol Pharmacol (2010) 0.81
Intensity modulated proton therapy for postmastectomy radiation of bilateral implant reconstructed breasts: a treatment planning study. Radiother Oncol (2013) 0.81
Dynamic control of hERG/I(Kr) by PKA-mediated interactions with 14-3-3. Novartis Found Symp (2005) 0.80
Time to screen for congenital toxoplasmosis? Clin Infect Dis (2006) 0.80
The International Congress on Toxoplasmosis. Int J Parasitol (2004) 0.80
The Impact of HIV Coinfection on Cerebral Malaria Pathogenesis. J Neuroparasitology (2012) 0.79
Natural selection's challenge to the cancer stem cell hypothesis. Med Hypotheses (2008) 0.79
Inhibition and structure of Toxoplasma gondii purine nucleoside phosphorylase. Eukaryot Cell (2014) 0.79
Mechanisms underlying the protein-kinase mediated regulation of the HERG potassium channel synthesis. Biochim Biophys Acta (2012) 0.79
Role of the parafusin orthologue, PRP1, in microneme exocytosis and cell invasion in Toxoplasma gondii. Cell Microbiol (2003) 0.78
Sequence and structure-specific elements of HERG mRNA determine channel synthesis and trafficking efficiency. FASEB J (2013) 0.77
Partially dominant mutant channel defect corresponding with intermediate LQT2 phenotype. Pacing Clin Electrophysiol (2011) 0.76
The Drosophila DmGluRA is required for social interaction and memory. Front Pharmacol (2013) 0.76
A dual mechanism for I(Ks) current reduction by the pathogenic mutation KCNQ1-S277L. Pacing Clin Electrophysiol (2011) 0.76
The use of Bcl-2 over-expression to stabilize hybridomas specific to the HERG potassium channel. J Immunol Methods (2011) 0.75