Published in Proc Natl Acad Sci U S A on February 14, 2011
Cell division in Apicomplexan parasites is organized by a homolog of the striated rootlet fiber of algal flagella. PLoS Biol (2012) 1.67
A novel bipartite centrosome coordinates the apicomplexan cell cycle. PLoS Biol (2015) 1.60
Holocentric chromosomes: convergent evolution, meiotic adaptations, and genomic analysis. Chromosome Res (2012) 1.23
The Toxoplasma gondii calcium-dependent protein kinase 7 is involved in early steps of parasite division and is crucial for parasite survival. Cell Microbiol (2013) 1.08
The Toxoplasma gondii centrosome is the platform for internal daughter budding as revealed by a Nek1 kinase mutant. J Cell Sci (2013) 0.99
A SAS-6-like protein suggests that the Toxoplasma conoid complex evolved from flagellar components. Eukaryot Cell (2013) 0.97
Lysine acetyltransferase GCN5b interacts with AP2 factors and is required for Toxoplasma gondii proliferation. PLoS Pathog (2014) 0.96
The histone code of Toxoplasma gondii comprises conserved and unique posttranslational modifications. MBio (2013) 0.93
Chromatin modifications, epigenetics, and how protozoan parasites regulate their lives. Trends Parasitol (2012) 0.93
A putative homologue of CDC20/CDH1 in the malaria parasite is essential for male gamete development. PLoS Pathog (2012) 0.89
Lytic Cycle of Toxoplasma gondii: 15 Years Later. Annu Rev Microbiol (2015) 0.88
Discovery of a splicing regulator required for cell cycle progression. PLoS Genet (2013) 0.86
The Ubiquitin Proteome of Toxoplasma gondii Reveals Roles for Protein Ubiquitination in Cell-Cycle Transitions. Cell Host Microbe (2015) 0.86
Toxoplasma gondii chromodomain protein 1 binds to heterochromatin and colocalises with centromeres and telomeres at the nuclear periphery. PLoS One (2012) 0.85
The apical complex provides a regulated gateway for secretion of invasion factors in Toxoplasma. PLoS Pathog (2014) 0.85
Genome cartography: charting the apicomplexan genome. Trends Parasitol (2011) 0.83
The Toxoplasma gondii kinetochore is required for centrosome association with the centrocone (spindle pole). Cell Microbiol (2013) 0.82
Genetic manipulation of the Toxoplasma gondii genome by fosmid recombineering. MBio (2014) 0.81
Centromere-associated repeat arrays on Trypanosoma brucei chromosomes are much more extensive than predicted. BMC Genomics (2012) 0.81
Targeting Toxoplasma tubules: tubulin, microtubules, and associated proteins in a human pathogen. Eukaryot Cell (2014) 0.80
Compartmentalized Toxoplasma EB1 bundles spindle microtubules to secure accurate chromosome segregation. Mol Biol Cell (2015) 0.79
Characterization of Toxoplasma gondii subtelomeric-like regions: identification of a long-range compositional bias that is also associated with gene-poor regions. BMC Genomics (2014) 0.79
How do microbial pathogens make CENs? PLoS Pathog (2012) 0.79
Histone H3 Variants in Trichomonas vaginalis. Eukaryot Cell (2012) 0.79
Protein palmitoylation and pathogenesis in apicomplexan parasites. J Biomed Biotechnol (2012) 0.78
Toxoplasma gondii Arginine Methyltransferase 1 (PRMT1) Is Necessary for Centrosome Dynamics during Tachyzoite Cell Division. MBio (2016) 0.78
O-fucosylated glycoproteins form assemblies in close proximity to the nuclear pore complexes of Toxoplasma gondii. Proc Natl Acad Sci U S A (2016) 0.76
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Specialising the parasite nucleus: Pores, lamins, chromatin, and diversity. PLoS Pathog (2017) 0.75
Checkpoints of apicomplexan cell division identified in Toxoplasma gondii. PLoS Pathog (2017) 0.75
Centromeric chromatin exhibits a histone modification pattern that is distinct from both euchromatin and heterochromatin. Nat Struct Mol Biol (2004) 4.95
The role of Drosophila CID in kinetochore formation, cell-cycle progression and heterochromatin interactions. Nat Cell Biol (2001) 3.59
Intracellular parasite invasion strategies. Science (2004) 3.36
Distinct protein interaction domains and protein spreading in a complex centromere. Genes Dev (2000) 3.09
Characterizing transcription factor binding sites using formaldehyde crosslinking and immunoprecipitation. Methods (2002) 2.99
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Composite genome map and recombination parameters derived from three archetypal lineages of Toxoplasma gondii. Nucleic Acids Res (2005) 2.64
High-throughput growth assay for Toxoplasma gondii using yellow fluorescent protein. Antimicrob Agents Chemother (2003) 2.62
Reading signals on the nucleosome with a new nomenclature for modified histones. Nat Struct Mol Biol (2005) 2.60
The fine structure and reproduction of Toxoplasma gondii. J Parasitol (1968) 2.53
Adaptive evolution of Cid, a centromere-specific histone in Drosophila. Genetics (2001) 2.45
Characterization of the subpellicular network, a filamentous membrane skeletal component in the parasite Toxoplasma gondii. Mol Biochem Parasitol (2001) 2.44
Cytoskeletal components of an invasion machine--the apical complex of Toxoplasma gondii. PLoS Pathog (2006) 2.43
A brief illustrated guide to the ultrastructure of Plasmodium falciparum asexual blood stages. Parasitol Today (2000) 2.04
A MORN-repeat protein is a dynamic component of the Toxoplasma gondii cell division apparatus. J Cell Sci (2006) 2.02
The plastid of Toxoplasma gondii is divided by association with the centrosomes. J Cell Biol (2000) 1.95
A network of nuclear envelope membrane proteins linking centromeres to microtubules. Cell (2008) 1.88
Structure, dynamics, and evolution of centromeric nucleosomes. Proc Natl Acad Sci U S A (2007) 1.81
Epigenomic modifications predict active promoters and gene structure in Toxoplasma gondii. PLoS Pathog (2007) 1.69
Plasmodium falciparum heterochromatin protein 1 marks genomic loci linked to phenotypic variation of exported virulence factors. PLoS Pathog (2009) 1.67
Building the perfect parasite: cell division in apicomplexa. PLoS Pathog (2007) 1.67
Functional identification of the Plasmodium centromere and generation of a Plasmodium artificial chromosome. Cell Host Microbe (2010) 1.63
Diverse roles of HP1 proteins in heterochromatin assembly and functions in fission yeast. Proc Natl Acad Sci U S A (2009) 1.60
Construction, characterization, and complementation of a conditional-lethal DNA topoisomerase IIalpha mutant human cell line. Mol Biol Cell (2004) 1.53
The fine structure of the erythrocytic stages of three avian malarial parasites, Plasmodium fallax, P. lophurae, and P. cathemerium. Am J Trop Med Hyg (1966) 1.46
The toxoplasma apicoplast phosphate translocator links cytosolic and apicoplast metabolism and is essential for parasite survival. Cell Host Microbe (2009) 1.34
Targeting of soluble proteins to the rhoptries and micronemes in Toxoplasma gondii. Mol Biochem Parasitol (2001) 1.28
The cell cycle and Toxoplasma gondii cell division: tightly knit or loosely stitched? Int J Parasitol (2008) 1.25
MORN1 has a conserved role in asexual and sexual development across the apicomplexa. Eukaryot Cell (2008) 1.20
Histones and histone modifications in protozoan parasites. Cell Microbiol (2006) 1.20
Gametogenesis and fertilization in Plasmodium yoelii nigeriensis: a transmission electron microscope study. Proc R Soc Lond B Biol Sci (1976) 1.19
Evidence on the chromosomal location of centromeric DNA in Plasmodium falciparum from etoposide-mediated topoisomerase-II cleavage. Proc Natl Acad Sci U S A (2006) 1.15
Mapping of a human centromere onto the DNA by topoisomerase II cleavage. EMBO Rep (2000) 1.15
Repetitive DNA is associated with centromeric domains in Trypanosoma brucei but not Trypanosoma cruzi. Genome Biol (2007) 1.13
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Plastid segregation and cell division in the apicomplexan parasite Sarcocystis neurona. J Cell Sci (2005) 1.00
Chromatin modifications: implications in the regulation of gene expression in Toxoplasma gondii. Cell Microbiol (2010) 0.96
Studies on nuclear division of a malarial parasite under pyrimethamine treatment. J Cell Biol (1968) 0.92
Ultrastructural differentiation of Toxoplasma gondii schizonts (types B to E) and gamonts in the intestines of cats fed bradyzoites. Int J Parasitol (2004) 0.92
Ultrastructure of shizonts and merozoites of Sarcocystis falcatula in the lungs of budgerigars (Melopsittacus undulatus). J Parasitol (1999) 0.91
Morphology and behaviour of dinoflagellate chromosomes during the cell cycle and mitosis. J Cell Sci (2000) 0.90
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Histone H3 and H3.3 variants in the protozoan pathogens Plasmodium falciparum and Toxoplasma gondii. DNA Seq (2003) 0.83
Bright and stable near-infrared fluorescent protein for in vivo imaging. Nat Biotechnol (2011) 4.14
Dynamics of neutrophil migration in lymph nodes during infection. Immunity (2008) 2.70
High-throughput growth assay for Toxoplasma gondii using yellow fluorescent protein. Antimicrob Agents Chemother (2003) 2.62
CD40 induces macrophage anti-Toxoplasma gondii activity by triggering autophagy-dependent fusion of pathogen-containing vacuoles and lysosomes. J Clin Invest (2006) 2.59
Daughter cell assembly in the protozoan parasite Toxoplasma gondii. Mol Biol Cell (2002) 2.19
A MORN-repeat protein is a dynamic component of the Toxoplasma gondii cell division apparatus. J Cell Sci (2006) 2.02
Apicoplast fatty acid synthesis is essential for organelle biogenesis and parasite survival in Toxoplasma gondii. Proc Natl Acad Sci U S A (2006) 1.93
Parasitic infections: Time to tackle cryptosporidiosis. Nature (2013) 1.89
Toxoplasma gondii Tic20 is essential for apicoplast protein import. Proc Natl Acad Sci U S A (2008) 1.78
A dynamin is required for the biogenesis of secretory organelles in Toxoplasma gondii. Curr Biol (2009) 1.77
Dynamics of T cell, antigen-presenting cell, and pathogen interactions during recall responses in the lymph node. Immunity (2009) 1.71
Epigenomic modifications predict active promoters and gene structure in Toxoplasma gondii. PLoS Pathog (2007) 1.69
Cell division in Apicomplexan parasites is organized by a homolog of the striated rootlet fiber of algal flagella. PLoS Biol (2012) 1.67
Class I major histocompatibility complex presentation of antigens that escape from the parasitophorous vacuole of Toxoplasma gondii. Infect Immun (2005) 1.66
Motile invaded neutrophils in the small intestine of Toxoplasma gondii-infected mice reveal a potential mechanism for parasite spread. Proc Natl Acad Sci U S A (2013) 1.65
Attenuated Plasmodium yoelii lacking purine nucleoside phosphorylase confer protective immunity. Nat Med (2008) 1.65
An analytical pipeline for genomic representations used for cytosine methylation studies. Bioinformatics (2008) 1.64
Post-translational modifications to Toxoplasma gondii alpha- and beta-tubulins include novel C-terminal methylation. J Proteome Res (2010) 1.64
Genetic evidence that an endosymbiont-derived endoplasmic reticulum-associated protein degradation (ERAD) system functions in import of apicoplast proteins. J Biol Chem (2009) 1.55
Distinct mechanisms govern proteolytic shedding of a key invasion protein in apicomplexan pathogens. Mol Microbiol (2005) 1.45
Apicoplast isoprenoid precursor synthesis and the molecular basis of fosmidomycin resistance in Toxoplasma gondii. J Exp Med (2011) 1.43
Targeting a prokaryotic protein in a eukaryotic pathogen: identification of lead compounds against cryptosporidiosis. Chem Biol (2008) 1.43
Cryptosporidium parvum IMP dehydrogenase: identification of functional, structural, and dynamic properties that can be exploited for drug design. J Biol Chem (2004) 1.43
Forward genetic analysis of the apicomplexan cell division cycle in Toxoplasma gondii. PLoS Pathog (2008) 1.38
Dynamic imaging of T cell-parasite interactions in the brains of mice chronically infected with Toxoplasma gondii. J Immunol (2009) 1.35
Targeting a novel Plasmodium falciparum purine recycling pathway with specific immucillins. J Biol Chem (2004) 1.34
The toxoplasma apicoplast phosphate translocator links cytosolic and apicoplast metabolism and is essential for parasite survival. Cell Host Microbe (2009) 1.34
Fluorescent protein tagging in Toxoplasma gondii: identification of a novel inner membrane complex component conserved among Apicomplexa. Mol Biochem Parasitol (2004) 1.34
A systematic screen to discover and analyze apicoplast proteins identifies a conserved and essential protein import factor. PLoS Pathog (2011) 1.29
A screening pipeline for antiparasitic agents targeting cryptosporidium inosine monophosphate dehydrogenase. PLoS Negl Trop Dis (2010) 1.29
Noninvasive real-time monitoring of liver-stage development of bioluminescent Plasmodium parasites. J Infect Dis (2009) 1.28
Energetic mapping of transition state analogue interactions with human and Plasmodium falciparum purine nucleoside phosphorylases. J Biol Chem (2005) 1.28
Plasmodium falciparum purine nucleoside phosphorylase: crystal structures, immucillin inhibitors, and dual catalytic function. J Biol Chem (2004) 1.26
Transition state analogue inhibitors of purine nucleoside phosphorylase from Plasmodium falciparum. J Biol Chem (2001) 1.25
The Toxoplasma gondii rhoptry protein ROP4 is secreted into the parasitophorous vacuole and becomes phosphorylated in infected cells. Eukaryot Cell (2004) 1.25
Antiapicoplast and gametocytocidal screening to identify the mechanisms of action of compounds within the malaria box. Antimicrob Agents Chemother (2013) 1.25
Purine-less death in Plasmodium falciparum induced by immucillin-H, a transition state analogue of purine nucleoside phosphorylase. J Biol Chem (2001) 1.24
Mitochondrial metabolism of glucose and glutamine is required for intracellular growth of Toxoplasma gondii. Cell Host Microbe (2012) 1.22
A Toxoplasma MORN1 null mutant undergoes repeated divisions but is defective in basal assembly, apicoplast division and cytokinesis. PLoS One (2010) 1.21
A novel dynamin-related protein has been recruited for apicoplast fission in Toxoplasma gondii. Curr Biol (2009) 1.20
Make it or take it: fatty acid metabolism of apicomplexan parasites. Eukaryot Cell (2007) 1.20
Autophagy protein Atg3 is essential for maintaining mitochondrial integrity and for normal intracellular development of Toxoplasma gondii tachyzoites. PLoS Pathog (2011) 1.19
TgSUB2 is a Toxoplasma gondii rhoptry organelle processing proteinase. Mol Microbiol (2003) 1.19
Improved transfection and new selectable markers for the rodent malaria parasite Plasmodium yoelii. Mol Biochem Parasitol (2006) 1.14
The algal past and parasite present of the apicoplast. Annu Rev Microbiol (2013) 1.11
Optimization of benzoxazole-based inhibitors of Cryptosporidium parvum inosine 5'-monophosphate dehydrogenase. J Med Chem (2013) 1.09
Mining the Plasmodium genome database to define organellar function: what does the apicoplast do? Philos Trans R Soc Lond B Biol Sci (2002) 1.09
Apicoplast and endoplasmic reticulum cooperate in fatty acid biosynthesis in apicomplexan parasite Toxoplasma gondii. J Biol Chem (2011) 1.09
Computational analysis and experimental validation of gene predictions in Toxoplasma gondii. PLoS One (2008) 1.08
Identification of a sporozoite-specific member of the Toxoplasma SAG superfamily via genetic complementation. Mol Microbiol (2004) 1.07
Intraepithelial gammadelta+ lymphocytes maintain the integrity of intestinal epithelial tight junctions in response to infection. Gastroenterology (2006) 1.07
Expression variance, biochemical and immunological properties of Toxoplasma gondii dense granule protein GRA7. Microbes Infect (2002) 1.05
Toxoplasma gondii and Cryptosporidium parvum lack detectable DNA cytosine methylation. Eukaryot Cell (2008) 1.03
Validation of IMP dehydrogenase inhibitors in a mouse model of cryptosporidiosis. Antimicrob Agents Chemother (2013) 1.03
Identification and characterisation of a regulatory region in the Toxoplasma gondii hsp70 genomic locus. Int J Parasitol (2004) 1.03
Toxoplasma gondii protease TgSUB1 is required for cell surface processing of micronemal adhesive complexes and efficient adhesion of tachyzoites. Cell Microbiol (2010) 1.01
Plasmodium falciparum purine nucleoside phosphorylase is critical for viability of malaria parasites. J Biol Chem (2008) 1.01
Selective and potent urea inhibitors of cryptosporidium parvum inosine 5'-monophosphate dehydrogenase. J Med Chem (2012) 1.01
The Toxoplasma nuclear factor TgAP2XI-4 controls bradyzoite gene expression and cyst formation. Mol Microbiol (2012) 1.01
Location, location, location: trafficking and function of secreted proteases of Toxoplasma and Plasmodium. Traffic (2004) 1.00
Proteolytic processing of the Cryptosporidium glycoprotein gp40/15 by human furin and by a parasite-derived furin-like protease activity. Infect Immun (2006) 1.00
Plastid segregation and cell division in the apicomplexan parasite Sarcocystis neurona. J Cell Sci (2005) 1.00
Structure-activity relationship study of selective benzimidazole-based inhibitors of Cryptosporidium parvum IMPDH. Bioorg Med Chem Lett (2012) 1.00
Comprehensive proteomic analysis of membrane proteins in Toxoplasma gondii. Mol Cell Proteomics (2010) 1.00
Cyclic nucleotide kinases and tachyzoite-bradyzoite transition in Toxoplasma gondii. Int J Parasitol (2005) 0.99
The cell biology of secondary endosymbiosis--how parasites build, divide and segregate the apicoplast. Mol Microbiol (2006) 0.97
EPIC-DB: a proteomics database for studying Apicomplexan organisms. BMC Genomics (2009) 0.96
High-mobility-group box nuclear factors of Plasmodium falciparum. Eukaryot Cell (2006) 0.96
Lipid synthesis in protozoan parasites: a comparison between kinetoplastids and apicomplexans. Prog Lipid Res (2013) 0.96
Toxoplasma gondii relies on both host and parasite isoprenoids and can be rendered sensitive to atorvastatin. PLoS Pathog (2013) 0.95
Structural and metabolic specificity of methylthiocoformycin for malarial adenosine deaminases. Biochemistry (2009) 0.95
cDNA cloning and expression of UDP-N-acetyl-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase T1 from Toxoplasma gondii. Mol Biochem Parasitol (2003) 0.95
The prodomain of Toxoplasma gondii GPI-anchored subtilase TgSUB1 mediates its targeting to micronemes. Traffic (2008) 0.95
Cyclin-dependent kinase TPK2 is a critical cell cycle regulator in Toxoplasma gondii. Mol Microbiol (2002) 0.94
Genetic rescue of a Toxoplasma gondii conditional cell cycle mutant. Mol Microbiol (2005) 0.94
Prodrug activation by Cryptosporidium thymidine kinase. J Biol Chem (2010) 0.94
High mobility group protein HMGB2 is a critical regulator of plasmodium oocyst development. J Biol Chem (2008) 0.94
Phthalazinone inhibitors of inosine-5'-monophosphate dehydrogenase from Cryptosporidium parvum. Bioorg Med Chem Lett (2012) 0.94
Plasmodium protease ROM1 is important for proper formation of the parasitophorous vacuole. PLoS Pathog (2011) 0.93
The histone code of Toxoplasma gondii comprises conserved and unique posttranslational modifications. MBio (2013) 0.93
Chromatin modifications, epigenetics, and how protozoan parasites regulate their lives. Trends Parasitol (2012) 0.93
A requirement for the Vgamma1+ subset of peripheral gammadelta T cells in the control of the systemic growth of Toxoplasma gondii and infection-induced pathology. J Immunol (2005) 0.92
More membranes, more proteins: complex protein import mechanisms into secondary plastids. Protist (2010) 0.92
The Impact of HIV and Malaria Coinfection: What Is Known and Suggested Venues for Further Study. Interdiscip Perspect Infect Dis (2009) 0.92
Isolation and characterization of TgVP1, a type I vacuolar H+-translocating pyrophosphatase from Toxoplasma gondii. The dynamics of its subcellular localization and the cellular effects of a diphosphonate inhibitor. J Biol Chem (2002) 0.91
Tic22 is an essential chaperone required for protein import into the apicoplast. J Biol Chem (2012) 0.91
Toxoplasma gondii purine nucleoside phosphorylase biochemical characterization, inhibitor profiles, and comparison with the Plasmodium falciparum ortholog. J Biol Chem (2006) 0.90
Effect of dietary p-aminobenzoic acid on murine Plasmodium yoelii infection. J Infect Dis (2003) 0.90
Analysis of the glycoproteome of Toxoplasma gondii using lectin affinity chromatography and tandem mass spectrometry. Microbes Infect (2011) 0.90
Plasmodium falciparum: growth response to potassium channel blocking compounds. Exp Parasitol (2008) 0.90
Characterization of PfMyb1 transcription factor during erythrocytic development of 3D7 and F12 Plasmodium falciparum clones. Mol Biochem Parasitol (2004) 0.89
Toxoplasma transcription factor TgAP2XI-5 regulates the expression of genes involved in parasite virulence and host invasion. J Biol Chem (2013) 0.89
Toxoplasma gondii proteomics. Expert Rev Proteomics (2009) 0.89
Plastid-targeting peptides from the chlorarachniophyte Bigelowiella natans. J Eukaryot Microbiol (2004) 0.89
Characterization of two putative potassium channels in Plasmodium falciparum. Malar J (2008) 0.89