Multiple sclerosis genetics.

PubWeight™: 1.04‹?› | Rank: Top 15%

🔗 View Article (PMID 18219814)

Published in Curr Top Microbiol Immunol on January 01, 2008

Authors

J P McElroy1, J R Oksenberg

Author Affiliations

1: Department of Neurology, School of Medicine, University of California at San Francisco, San Francisco, CA 94143, USA.

Articles citing this

Multiple sclerosis genetics--is the glass half full, or half empty? Nat Rev Neurol (2010) 1.15

Genome wide association for addiction: replicated results and comparisons of two analytic approaches. PLoS One (2010) 1.04

IL2RA/CD25 gene polymorphisms: uneven association with multiple sclerosis (MS) and type 1 diabetes (T1D). PLoS One (2009) 1.04

Genomic regions identified by overlapping clusters of nominally-positive SNPs from genome-wide studies of alcohol and illegal substance dependence. PLoS One (2011) 1.00

Association between protective and deleterious HLA alleles with multiple sclerosis in Central East Sardinia. PLoS One (2009) 1.00

Refining the association of MHC with multiple sclerosis in African Americans. Hum Mol Genet (2010) 0.96

Common variants in polygenic schizophrenia. Genome Biol (2009) 0.91

Multiple sclerosis risk variant HLA-DRB1*1501 associates with high expression of DRB1 gene in different human populations. PLoS One (2012) 0.90

"Replicated" genome wide association for dependence on illegal substances: genomic regions identified by overlapping clusters of nominally positive SNPs. Am J Med Genet B Neuropsychiatr Genet (2010) 0.89

Tag-SNP analysis of the GFI1-EVI5-RPL5-FAM69 risk locus for multiple sclerosis. Eur J Hum Genet (2010) 0.87

Potential triggers of MS. Results Probl Cell Differ (2010) 0.87

Identification of a functional variant in the KIF5A-CYP27B1-METTL1-FAM119B locus associated with multiple sclerosis. J Med Genet (2012) 0.85

Hexose-6-phosphate dehydrogenase: a new risk gene for multiple sclerosis. Eur J Hum Genet (2009) 0.78

SNP-based analysis of the HLA locus in Japanese multiple sclerosis patients. Genes Immun (2011) 0.77

Replication study of multiple sclerosis (MS) susceptibility alleles and correlation of DNA-variants with disease features in a cohort of Austrian MS patients. Neurogenetics (2012) 0.76

Articles by these authors

The influence of the proinflammatory cytokine, osteopontin, on autoimmune demyelinating disease. Science (2001) 4.89

A complete genomic screen for multiple sclerosis underscores a role for the major histocompatability complex. The Multiple Sclerosis Genetics Group. Nat Genet (1996) 2.98

Clinical characteristics of African Americans vs Caucasian Americans with multiple sclerosis. Neurology (2004) 2.50

B cell repertoire diversity and clonal expansion in multiple sclerosis brain lesions. J Immunol (1999) 2.06

HLA-DR2 dose effect on susceptibility to multiple sclerosis and influence on disease course. Am J Hum Genet (2003) 2.02

Characterizing the mechanisms of progression in multiple sclerosis: evidence and new hypotheses for future directions. Arch Neurol (2005) 1.69

Linkage of the MHC to familial multiple sclerosis suggests genetic heterogeneity. The Multiple Sclerosis Genetics Group. Hum Mol Genet (1998) 1.63

Multifactor dimensionality reduction reveals gene-gene interactions associated with multiple sclerosis susceptibility in African Americans. Genes Immun (2006) 1.56

Suppressive vaccination with DNA encoding a variable region gene of the T-cell receptor prevents autoimmune encephalomyelitis and activates Th2 immunity. Nat Med (1996) 1.47

Analysis of antibody gene rearrangement, usage, and specificity in chronic focal encephalitis. Neurology (2002) 1.45

Genetic basis for clinical expression in multiple sclerosis. Brain (2002) 1.43

Predominant expression of T cell receptor V alpha 7 in tumor-infiltrating lymphocytes of uveal melanoma. Science (1990) 1.39

Genotype-Phenotype correlations in multiple sclerosis: HLA genes influence disease severity inferred by 1HMR spectroscopy and MRI measures. Brain (2008) 1.37

Multiple sclerosis susceptibility alleles in African Americans. Genes Immun (2009) 1.32

Analysis of T cell receptor repertoire of muscle-infiltrating T lymphocytes in polymyositis. Restricted V alpha/beta rearrangements may indicate antigen-driven selection. J Clin Invest (1993) 1.23

PTPRC (CD45) is not associated with the development of multiple sclerosis in U.S. patients. Nat Genet (2001) 1.15

Interferon beta-1b inhibits gelatinase secretion and in vitro migration of human T cells: a possible mechanism for treatment efficacy in multiple sclerosis. Ann Neurol (1996) 1.14

Interaction of the pertussis toxin peptide containing residues 30-42 with DR1 and the T-cell receptors of 12 human T-cell clones. Proc Natl Acad Sci U S A (1992) 1.12

Maternal-paternal histocompatibility: lack of association with habitual abortions. Fertil Steril (1984) 1.10

Analysis of the T cell repertoire using the PCR and specific oligonucleotide primers. Biotechniques (1992) 1.06

Familial effects on the clinical course of multiple sclerosis. Neurology (2007) 1.00

Multiple sclerosis and oligodendroglioma. Mult Scler (2001) 0.98

Perivascular T cells express the pro-inflammatory chemokine RANTES mRNA in multiple sclerosis lesions. Scand J Immunol (1997) 0.98

APOE epsilon variation in multiple sclerosis susceptibility and disease severity: some answers. Neurology (2006) 0.97

Mixed lymphocyte reactivity nonresponsiveness in couples with multiple spontaneous abortions. Fertil Steril (1983) 0.96

CC-chemokine receptor 5 polymorphism and age of onset in familial multiple sclerosis. Multiple Sclerosis Genetics Group. Immunogenetics (2000) 0.95

A non-synonymous SNP within membrane metalloendopeptidase-like 1 (MMEL1) is associated with multiple sclerosis. Genes Immun (2010) 0.95

Local-clonal expansion of infiltrating T lymphocytes in chronic encephalitis of Rasmussen. J Immunol (1997) 0.95

Common viruses associated with lower pediatric multiple sclerosis risk. Neurology (2011) 0.95

Transcriptional analysis of multiple sclerosis brain lesions reveals a complex pattern of cytokine expression. J Immunol (2000) 0.94

A second-generation genomic screen for multiple sclerosis. Am J Hum Genet (2004) 0.94

A cytokine gene screen uncovers SOCS1 as genetic risk factor for multiple sclerosis. Genes Immun (2011) 0.94

Gamma delta T cell receptor repertoire in brain lesions of patients with multiple sclerosis. J Neuroimmunol (1993) 0.93

APOBEC3H haplotypes and HIV-1 pro-viral vif DNA sequence diversity in early untreated human immunodeficiency virus-1 infection. Hum Immunol (2010) 0.92

Examination of seven candidate regions for multiple sclerosis: strong evidence of linkage to chromosome 1q44. Genes Immun (2006) 0.90

Lymphocytes cytotoxic to uveal and skin melanoma cells from peripheral blood of ocular melanoma patients. Cancer Immunol Immunother (1991) 0.90

Characterization of T-cell receptor alpha beta repertoire in synovial tissue from different temporal phases of rheumatoid arthritis. Scand J Immunol (1992) 0.89

Osteopontin polymorphisms and disease course in multiple sclerosis. Genes Immun (2003) 0.89

Cellular immunity in human milk. Am J Reprod Immunol Microbiol (1985) 0.89

Interaction between HLA-DR2 and abnormal brain MRI in optic neuritis and early MS. Optic Neuritis Study Group. Neurology (2000) 0.88

Longitudinal system-based analysis of transcriptional responses to type I interferons. Physiol Genomics (2009) 0.88

The immunobiology of multiple sclerosis: an autoimmune disease of the central nervous system. Neurobiol Dis (1999) 0.87

Antigen-presenting cells in human decidual tissue. Am J Reprod Immunol Microbiol (1986) 0.86

Single nucleotide polymorphisms in MHC2TA, the gene encoding the MHC class II transactivator (CIITA). Genes Immun (2002) 0.85

Association of susceptibility to multiple sclerosis with TCR genes. Immunol Today (1992) 0.85

Linkage and association analysis of chromosome 19q13 in multiple sclerosis. Neurogenetics (2001) 0.84

Allelic association of sequence variants in the herpes virus entry mediator-B gene (PVRL2) with the severity of multiple sclerosis. Genes Immun (2006) 0.84

The epigenetics of multiple sclerosis: clues to etiology and a rationale for immune therapy. Annu Rev Neurosci (1994) 0.84

Characterization of the TCRB chain repertoire in the New World monkey Callithrix jacchus. J Immunol (1997) 0.84

Pharmacogenomic analysis of interferon receptor polymorphisms in multiple sclerosis. Genes Immun (2003) 0.84

T-cell receptor V-gene usage in synovial fluid lymphocytes of patients with chronic arthritis. Hum Immunol (1993) 0.83

Analysis of IL4R haplotypes in predisposition to multiple sclerosis. Genes Immun (2004) 0.83

The HLA locus and multiple sclerosis in Sicily. Neurology (2005) 0.83

Genetic variation in nitric oxide synthase 2A (NOS2A) and risk for multiple sclerosis. Genes Immun (2008) 0.82

In vitro suppression of murine blastocysts growth by sera from women with reproductive disorders. Am J Reprod Immunol Microbiol (1986) 0.82

HLA-D clusters associated with DR2 and the definition of HLA-D"AZH": a new DR2 related HLA-D specificity in Israel. Tissue Antigens (1984) 0.82

Sequence variation in the transforming growth factor-beta1 (TGFB1) gene and multiple sclerosis susceptibility. J Neuroimmunol (2001) 0.82

Multiple sclerosis: a polygenic disease involving epistatic interactions, germline rearrangements and environmental effects. Neurogenetics (1997) 0.81

Opposing effects of the HLA-DRB1*0301-DQB1*0201 haplotype on the risk for multiple sclerosis in diverse Arab populations in Israel. Genes Immun (2010) 0.81

Evidence for the genetic role of human leukocyte antigens in low frequency DRB1*1501 multiple sclerosis patients in Israel. Mult Scler (1999) 0.80

The polymerase chain reaction for detection of T-cell antigen receptor expression. Curr Opin Immunol (1992) 0.80

Cyclic adenosine 3',5'-monophosphate metabolism in activated T-cell clones. Immunology (1989) 0.80

HLA-DP beta and susceptibility to multiple sclerosis: an analysis of caucasoid and Japanese patient populations. Hum Immunol (1990) 0.80

ApoE alleles, depression and positive affect in multiple sclerosis. Mult Scler (2009) 0.79

Limited allelic polymorphism in the human interleukin-3 gene. Mol Cell Probes (1998) 0.79

T-cell receptor gene usage of acetylcholine receptor-specific T-helper cells. Ann N Y Acad Sci (1993) 0.79

Evolution of the CCR5 Delta32 mutation based on haplotype variation in Jewish and Northern European population samples. Hum Immunol (2001) 0.79

Human leukocyte antigens (HLA) class I and class II on sperm cells studied at the serological, cellular, and genomic levels. Am J Reprod Immunol Microbiol (1987) 0.79

Clonal analysis of in vivo activated CD8+ cytotoxic T lymphocytes from a melanoma patient responsive to active specific immunotherapy. Cancer Immunol Immunother (1993) 0.78

Genetic associations with brain cortical thickness in multiple sclerosis. Genes Brain Behav (2015) 0.78

Increased incidence of certain TCR and HLA genes associated with myasthenia gravis in Italians. J Autoimmun (1990) 0.77

Chronic inflammatory diseases of the nervous system. Curr Opin Neurol (1998) 0.77

Copy number variation in pediatric multiple sclerosis. Mult Scler (2012) 0.77

New allelic polymorphisms in TAP genes. Immunogenetics (1994) 0.77

SNP-based analysis of the HLA locus in Japanese multiple sclerosis patients. Genes Immun (2011) 0.77

Transcriptional expression patterns triggered by chemically distinct neuroprotective molecules. Neuroscience (2012) 0.76

Longitudinal analysis of T-cell receptor gene use by CD8(+) T cells in early human immunodeficiency virus infection in patients receiving highly active antiretroviral therapy. Blood (2001) 0.76

Follow-up examination of linkage and association to chromosome 1q43 in multiple sclerosis. Genes Immun (2009) 0.76

Linkage analysis of candidate myelin genes in familial multiple sclerosis. Neurogenetics (1999) 0.76

Polymorphism in MS. Neurology (1992) 0.75

T-cell receptor repertoire V beta in alopecia areata. J Invest Dermatol (1995) 0.75

Limited heterogeneity of rearranged T-cell receptor V alpha transcripts in brains of multiple sclerosis patients. Nature (1991) 0.75

Two new HLA-B alleles, B*4422 and B*4704, identified in a study of families with autoimmunity. Tissue Antigens (2002) 0.75

HLA-DR, D recombination in a kidney transplant recipient. Hum Immunol (1982) 0.75

Differential display analysis of murine encephalitogenic mRNA. Int Immunol (1998) 0.75

Immunogenetics and heterogeneity in multiple sclerosis. Ann Neurol (1996) 0.75

Longitudinal analysis of B cell repertoire and antibody gene rearrangements during early HIV infection. Genes Immun (2005) 0.75

Histoincompatibility in couples with unexplained infertility. Fertil Steril (1985) 0.75

Antigen presenting cells in human decidual tissue. II: Accessory cells for the development of anti-trinitrophenyl cytotoxic T lymphocytes. J Reprod Immunol (1987) 0.75

Chromosome 17q22-q24 and multiple sclerosis genetic susceptibility. American-French Multiple Sclerosis Genetic Group. Genes Immun (1999) 0.75