Published in PLoS One on January 06, 2009
Differential micro RNA expression in PBMC from multiple sclerosis patients. PLoS One (2009) 1.98
Association of the AFF3 gene and IL2/IL21 gene region with juvenile idiopathic arthritis. Genes Immun (2010) 1.13
A knowledge-driven interaction analysis reveals potential neurodegenerative mechanism of multiple sclerosis susceptibility. Genes Immun (2011) 1.08
Genetic basis of alopecia areata: a roadmap for translational research. Dermatol Clin (2012) 1.03
Human IL2RA null mutation mediates immunodeficiency with lymphoproliferation and autoimmunity. Clin Immunol (2013) 0.95
Comorbidities at multiple sclerosis diagnosis. J Neurol (2013) 0.90
Polymorphisms in the IL2, IL2RA and IL2RB genes in multiple sclerosis risk. Eur J Hum Genet (2010) 0.83
Shared HLA Class II in Six Autoimmune Diseases in Latin America: A Meta-Analysis. Autoimmune Dis (2012) 0.83
Improving power of genome-wide association studies with weighted false discovery rate control and prioritized subset analysis. PLoS One (2012) 0.79
Determination of the real effect of genes identified in GWAS: the example of IL2RA in multiple sclerosis. Eur J Hum Genet (2011) 0.78
Sample reproducibility of genetic association using different multimarker TDTs in genome-wide association studies: characterization and a new approach. PLoS One (2012) 0.78
Plasma Levels of Soluble Interleukin-2 Receptor α: Associations With Clinical Cardiovascular Events and Genome-Wide Association Scan. Arterioscler Thromb Vasc Biol (2015) 0.77
Evaluation of in vivo T cell kinetics: use of heavy isotope labelling in type 1 diabetes. Clin Exp Immunol (2013) 0.76
Replication study of multiple sclerosis (MS) susceptibility alleles and correlation of DNA-variants with disease features in a cohort of Austrian MS patients. Neurogenetics (2012) 0.76
In-vitro characterization of novel and functional regulatory SNPs in the promoter region of IL2 and IL2R alpha in a Gabonese population. BMC Med Genet (2012) 0.75
A 33D1+ Dendritic Cell/Autoreactive CD4+ T Cell Circuit Maintains IL-2-Dependent Regulatory T Cells in the Spleen. J Immunol (2016) 0.75
Where is the causal variant? On the advantage of the family design over the case-control design in genetic association studies. Eur J Hum Genet (2015) 0.75
Haploview: analysis and visualization of LD and haplotype maps. Bioinformatics (2004) 125.23
New diagnostic criteria for multiple sclerosis: guidelines for research protocols. Ann Neurol (1983) 26.67
Risk alleles for multiple sclerosis identified by a genomewide study. N Engl J Med (2007) 17.06
A missense single-nucleotide polymorphism in a gene encoding a protein tyrosine phosphatase (PTPN22) is associated with rheumatoid arthritis. Am J Hum Genet (2004) 13.71
A tutorial on statistical methods for population association studies. Nat Rev Genet (2006) 12.49
A functional variant of lymphoid tyrosine phosphatase is associated with type I diabetes. Nat Genet (2004) 12.25
Multiple sclerosis. Lancet (2002) 7.11
Large-scale genetic fine mapping and genotype-phenotype associations implicate polymorphism in the IL2RA region in type 1 diabetes. Nat Genet (2007) 6.11
Interleukin 7 receptor alpha chain (IL7R) shows allelic and functional association with multiple sclerosis. Nat Genet (2007) 5.09
Polymorphisms in the tyrosine kinase 2 and interferon regulatory factor 5 genes are associated with systemic lupus erythematosus. Am J Hum Genet (2005) 4.80
Genetic association of the R620W polymorphism of protein tyrosine phosphatase PTPN22 with human SLE. Am J Hum Genet (2004) 4.46
Localization of a type 1 diabetes locus in the IL2RA/CD25 region by use of tag single-nucleotide polymorphisms. Am J Hum Genet (2005) 4.36
Variation in interleukin 7 receptor alpha chain (IL7R) influences risk of multiple sclerosis. Nat Genet (2007) 4.22
A functional variant in FCRL3, encoding Fc receptor-like 3, is associated with rheumatoid arthritis and several autoimmunities. Nat Genet (2005) 3.15
Clustering of autoimmune diseases in families with a high-risk for multiple sclerosis: a descriptive study. Lancet Neurol (2006) 2.77
Autoimmune disease in families with multiple sclerosis: a population-based study. Lancet Neurol (2007) 2.38
An insertion-deletion polymorphism in the interferon regulatory Factor 5 (IRF5) gene confers risk of inflammatory bowel diseases. Hum Mol Genet (2007) 2.14
Refining genetic associations in multiple sclerosis. Lancet Neurol (2008) 1.85
A specific CpG site demethylation in the human interleukin 2 gene promoter is an epigenetic memory. EMBO J (2006) 1.71
Interferon regulatory factor 5 (IRF5) gene variants are associated with multiple sclerosis in three distinct populations. J Med Genet (2008) 1.59
Toward further mapping of the association between the IL2RA locus and type 1 diabetes. Diabetes (2007) 1.38
Incidence of multiple sclerosis in the United Kingdom : findings from a population-based cohort. J Neurol (2007) 1.37
IL2RA/CD25 polymorphisms contribute to multiple sclerosis susceptibility. J Neurol (2007) 1.18
Familial recurrence rates and genetic models of multiple sclerosis. Am J Med Genet A (2005) 1.16
Analysis of the Fc receptor-like-3 (FCRL3) locus in Caucasians with autoimmune disorders suggests a complex pattern of disease association. J Clin Endocrinol Metab (2007) 1.13
Multiple sclerosis genetics. Curr Top Microbiol Immunol (2008) 1.04
Association of MS with thyroid disorders. Neurology (1999) 1.01
Analysis of IRF5 gene functional polymorphisms in rheumatoid arthritis. Arthritis Rheum (2006) 1.01
The high producer variant of the Fc-receptor like-3 (FCRL3) gene is involved in protection against multiple sclerosis. J Neuroimmunol (2008) 0.91
Multiple sclerosis in Gypsies from southern Spain: prevalence, mitochondrial DNA haplogroups and HLA class II association. Tissue Antigens (2008) 0.87
Familial occurrence of autoimmune diseases and autoantibodies in a Caucasian population of patients with systemic lupus erythematosus. Clin Rheumatol (2002) 0.87
Genetic loci linked to type 1 diabetes and multiple sclerosis families in Sardinia. BMC Med Genet (2008) 0.84
Genomewide study of multiple sclerosis. N Engl J Med (2007) 0.79
Oral fingolimod or intramuscular interferon for relapsing multiple sclerosis. N Engl J Med (2010) 13.82
Antigen microarrays identify unique serum autoantibody signatures in clinical and pathologic subtypes of multiple sclerosis. Proc Natl Acad Sci U S A (2008) 2.57
Toll-like receptor 2 and poly(ADP-ribose) polymerase 1 promote central nervous system neuroinflammation in progressive EAE. Nat Immunol (2009) 2.56
Fingolimod after natalizumab and the risk of short-term relapse. Neurology (2014) 1.96
Genome-wide pharmacogenomic analysis of the response to interferon beta therapy in multiple sclerosis. Arch Neurol (2008) 1.59
Local not systemic modulation of dendritic cell S1P receptors in lung blunts virus-specific immune responses to influenza. Mol Pharmacol (2008) 1.48
TNFRSF1A polymorphisms rs1800693 and rs4149584 in patients with multiple sclerosis. Neurology (2013) 1.47
Validation of diagnostic magnetic resonance imaging criteria for multiple sclerosis and response to interferon beta1a. Ann Neurol (2003) 1.39
[Neuropathy due to elongation of the ilioinguinal nerve]. Rev Neurol (2010) 1.38
Full pharmacological efficacy of a novel S1P1 agonist that does not require S1P-like headgroup interactions. Mol Pharmacol (2008) 1.36
A PRKAR1A mutation associated with primary pigmented nodular adrenocortical disease in 12 kindreds. J Clin Endocrinol Metab (2006) 1.35
Genome-wide CTCF distribution in vertebrates defines equivalent sites that aid the identification of disease-associated genes. Nat Struct Mol Biol (2011) 1.31
Differential cognitive impairment for diverse forms of multiple sclerosis. BMC Neurosci (2006) 1.19
IL2RA/CD25 polymorphisms contribute to multiple sclerosis susceptibility. J Neurol (2007) 1.18
Evidence that vasopressin V1b receptors mediate the transition to excessive drinking in ethanol-dependent rats. Addict Biol (2011) 1.17
Geographical variations in sex ratio trends over time in multiple sclerosis. PLoS One (2012) 1.12
Microarray analysis of hepatic gene expression identifies new genes involved in steatotic liver. Physiol Genomics (2009) 1.11
Fingolimod versus intramuscular interferon in patient subgroups from TRANSFORMS. J Neurol (2013) 1.06
Delayed reactions to drugs show levels of perforin, granzyme B, and Fas-L to be related to disease severity. J Allergy Clin Immunol (2002) 1.05
Switch to natalizumab versus fingolimod in active relapsing-remitting multiple sclerosis. Ann Neurol (2015) 1.04
Immunological markers of optimal response to natalizumab in multiple sclerosis. Arch Neurol (2012) 1.03
Country, sex, EDSS change and therapy choice independently predict treatment discontinuation in multiple sclerosis and clinically isolated syndrome. PLoS One (2012) 1.02
Effects of the multiple sclerosis associated -330 promoter polymorphism in IL2 allelic expression. J Neuroimmunol (2004) 1.02
CD40: novel association with Crohn's disease and replication in multiple sclerosis susceptibility. PLoS One (2010) 1.01
Genome-wide significant association of ANKRD55 rs6859219 and multiple sclerosis risk. J Med Genet (2013) 0.96
The efficacy of natalizumab in patients with multiple sclerosis according to level of disability: results of an observational study. Mult Scler (2010) 0.96
MANBA, CXCR5, SOX8, RPS6KB1 and ZBTB46 are genetic risk loci for multiple sclerosis. Brain (2013) 0.94
Protein tyrosine phosphatase gene (PTPN22) polymorphism in multiple sclerosis. J Neurol (2005) 0.93
Seasonal variation of relapse rate in multiple sclerosis is latitude dependent. Ann Neurol (2014) 0.91
The high producer variant of the Fc-receptor like-3 (FCRL3) gene is involved in protection against multiple sclerosis. J Neuroimmunol (2008) 0.91
Trans-10, cis-12- and cis-9, trans-11-conjugated linoleic acid isomers selectively modify HDL-apolipoprotein composition in apolipoprotein E knockout mice. J Nutr (2006) 0.90
Multiple sclerosis risk variant HLA-DRB1*1501 associates with high expression of DRB1 gene in different human populations. PLoS One (2012) 0.90
Genome-wide association study of multiple sclerosis confirms a novel locus at 5p13.1. PLoS One (2012) 0.90
Validation of the CD6 and TNFRSF1A loci as risk factors for multiple sclerosis in Spain. J Neuroimmunol (2010) 0.90
Persistence on therapy and propensity matched outcome comparison of two subcutaneous interferon beta 1a dosages for multiple sclerosis. PLoS One (2013) 0.89
Genetic diversity of influenza A(H1N1)2009 virus circulating during the season 2010-2011 in Spain. J Clin Virol (2011) 0.89
Rapid increase in resistance of Plasmodium falciparum to chloroquine-Fansidar in Uganda and the potential of amodiaquine-Fansidar as a better alternative. Acta Trop (2005) 0.89
Replication study of 10 genes showing evidence for association with multiple sclerosis: validation of TMEM39A, IL12B and CBLB [correction of CLBL] genes. Mult Scler (2011) 0.89
The C-terminal domain of the Plasmodium falciparum acyl-CoA synthetases PfACS1 and PfACS3 functions as ligand for ankyrin. Mol Biochem Parasitol (2003) 0.88
High susceptibility of a human oligodendroglial cell line to herpes simplex type 1 infection. J Neurovirol (2005) 0.88
Increasing age at disability milestones among MS patients in the MSBase Registry. J Neurol Sci (2012) 0.88
Cystathionine beta-synthase is essential for female reproductive function. Hum Mol Genet (2006) 0.88
Tag-SNP analysis of the GFI1-EVI5-RPL5-FAM69 risk locus for multiple sclerosis. Eur J Hum Genet (2010) 0.87
Skewed X inactivation of the normal allele in fully mutated female carriers determines the levels of FMRP in blood and the fragile X phenotype. Mol Diagn (2005) 0.87
Lipid-specific immunoglobulin M bands in cerebrospinal fluid are associated with a reduced risk of developing progressive multifocal leukoencephalopathy during treatment with natalizumab. Ann Neurol (2015) 0.86
Closing the case of APOE in multiple sclerosis: no association with disease risk in over 29 000 subjects. J Med Genet (2012) 0.86
Sphingosine 1-phosphate receptor agonists: a patent review (2010-2012). Expert Opin Ther Pat (2013) 0.86
Serum cytokines, mood and sleep after a qigong program: is qigong an effective psychobiological tool? J Health Psychol (2009) 0.86
Selective effect of conjugated linoleic acid isomers on atherosclerotic lesion development in apolipoprotein E knockout mice. Atherosclerosis (2006) 0.86
TRAIL/TRAIL receptor system and susceptibility to multiple sclerosis. PLoS One (2011) 0.86
Study of cerebral cavernous malformation in Spain and Portugal: high prevalence of a 14 bp deletion in exon 5 of MGC4607 (CCM2 gene). J Neurol (2007) 0.85
Relationship between the efficacy of rivastigmine and apolipoprotein E (epsilon4) in patients with mild to moderately severe Alzheimer disease. Alzheimer Dis Assoc Disord (2006) 0.85
Identification of a functional variant in the KIF5A-CYP27B1-METTL1-FAM119B locus associated with multiple sclerosis. J Med Genet (2012) 0.85
IFNAR1 and IFNAR2 polymorphisms confer susceptibility to multiple sclerosis but not to interferon-beta treatment response. J Neuroimmunol (2005) 0.85