Published in Med Biol Eng Comput on May 01, 2008
The effects of hemodynamic force on embryonic development. Microcirculation (2010) 1.66
Biomechanics of early cardiac development. Biomech Model Mechanobiol (2012) 1.00
Biomechanics of the chick embryonic heart outflow tract at HH18 using 4D optical coherence tomography imaging and computational modeling. PLoS One (2012) 0.99
Atrioventricular valve development: new perspectives on an old theme. Differentiation (2012) 0.98
Decreased levels of embryonic retinoic acid synthesis accelerate recovery from arterial growth delay in a mouse model of DiGeorge syndrome. Circ Res (2010) 0.94
4D shear stress maps of the developing heart using Doppler optical coherence tomography. Biomed Opt Express (2012) 0.93
Placental Origins of Chronic Disease. Physiol Rev (2016) 0.88
Fluorescence-based force/tension sensors: a novel tool to visualize mechanical forces in structural proteins in live cells. Antioxid Redox Signal (2014) 0.85
Critical transitions in early embryonic aortic arch patterning and hemodynamics. PLoS One (2013) 0.80
Use of computational fluid dynamics to estimate hemodynamic effects of respiration on hypoplastic left heart syndrome surgery: total cavopulmonary connection treatments. ScientificWorldJournal (2013) 0.79
Strain-induced tissue growth laws: applications to embryonic cardiovascular development. J Appl Mech Eng (2013) 0.76
Effect of Outflow Tract Banding on Embryonic Cardiac Hemodynamics. J Cardiovasc Dev Dis (2015) 0.75
A mechanosensory complex that mediates the endothelial cell response to fluid shear stress. Nature (2005) 6.86
The primary cilium as the cell's antenna: signaling at a sensory organelle. Science (2006) 6.79
Intracardiac fluid forces are an essential epigenetic factor for embryonic cardiogenesis. Nature (2003) 5.05
Endothelial cilia are fluid shear sensors that regulate calcium signaling and nitric oxide production through polycystin-1. Circulation (2008) 3.33
Vascular remodeling of the mouse yolk sac requires hemodynamic force. Development (2007) 3.26
Mechanotransduction and flow across the endothelial glycocalyx. Proc Natl Acad Sci U S A (2003) 2.93
Increased ventricular preload is compensated by myocyte proliferation in normal and hypoplastic fetal chick left ventricle. Circ Res (2007) 2.81
Cilia: tuning in to the cell's antenna. Curr Biol (2006) 2.68
Klf2 is an essential regulator of vascular hemodynamic forces in vivo. Dev Cell (2006) 2.26
Measuring hemodynamic changes during mammalian development. Am J Physiol Heart Circ Physiol (2004) 1.98
Molecular mechanisms of the vascular responses to haemodynamic forces. J Intern Med (2006) 1.98
Endothelial KLF2 links local arterial shear stress levels to the expression of vascular tone-regulating genes. Am J Pathol (2005) 1.98
From stem cells to viable autologous semilunar heart valve. Circulation (2005) 1.94
Fluid shear stress and the vascular endothelium: for better and for worse. Prog Biophys Mol Biol (2003) 1.92
Large variations in absolute wall shear stress levels within one species and between species. Atherosclerosis (2006) 1.87
Primary cilia of human endothelial cells disassemble under laminar shear stress. J Cell Biol (2004) 1.86
Shear stress biology of the endothelium. Ann Biomed Eng (2005) 1.84
Orpk mouse model of polycystic kidney disease reveals essential role of primary cilia in pancreatic tissue organization. Development (2004) 1.73
Rapid three-dimensional imaging and analysis of the beating embryonic heart reveals functional changes during development. Dev Dyn (2006) 1.68
Shear stress regulation of Krüppel-like factor 2 expression is flow pattern-specific. Biochem Biophys Res Commun (2006) 1.57
In vivo micro particle image velocimetry measurements of blood-plasma in the embryonic avian heart. J Biomech (2006) 1.53
Changes in shear stress-related gene expression after experimentally altered venous return in the chicken embryo. Circ Res (2005) 1.47
Systolic and diastolic ventricular function in the normal and extra-embryonic venous clipped chicken embryo of stage 24: a pressure-volume loop assessment. Ultrasound Obstet Gynecol (2007) 1.46
Unilateral vitelline vein ligation alters intracardiac blood flow patterns and morphogenesis in the chick embryo. Circ Res (1997) 1.44
Control of arterial branching morphogenesis in embryogenesis: go with the flow. Cardiovasc Res (2005) 1.39
Monocilia on chicken embryonic endocardium in low shear stress areas. Dev Dyn (2006) 1.36
Hemodynamics is a key epigenetic factor in development of the cardiac conduction system. Circ Res (2003) 1.35
Endothelial primary cilia in areas of disturbed flow are at the base of atherosclerosis. Atherosclerosis (2007) 1.32
High-frequency ultrasonographic imaging of avian cardiovascular development. Dev Dyn (2007) 1.29
Prolonged shear stress and KLF2 suppress constitutive proinflammatory transcription through inhibition of ATF2. Blood (2007) 1.27
Development-related changes in the expression of shear stress responsive genes KLF-2, ET-1, and NOS-3 in the developing cardiovascular system of chicken embryos. Dev Dyn (2004) 1.24
Digital three-dimensional atlas of quail development using high-resolution MRI. ScientificWorldJournal (2007) 1.23
The role of shear stress on ET-1, KLF2, and NOS-3 expression in the developing cardiovascular system of chicken embryos in a venous ligation model. Physiology (Bethesda) (2007) 1.21
Laminar shear stress acts as a switch to regulate divergent functions of NF-kappaB in endothelial cells. FASEB J (2007) 1.13
Extraembryonic venous obstructions lead to cardiovascular malformations and can be embryolethal. Cardiovasc Res (1999) 1.09
Effect of shear stress on vascular inflammation and plaque development. Curr Opin Lipidol (2007) 1.08
Global analysis of shear stress-responsive genes in vascular endothelial cells. J Atheroscler Thromb (2003) 1.07
Magnetic resonance microscopy of mouse embryos in utero. Anat Rec (2000) 1.04
Fluid shear stress and inner curvature remodeling of the embryonic heart. Choosing the right lane! ScientificWorldJournal (2008) 1.02
Inhibition of E-selectin gene expression by transforming growth factor beta in endothelial cells involves coactivator integration of Smad and nuclear factor kappaB-mediated signals. J Exp Med (2000) 1.02
Involvement of integrins, MAPK, and NF-kappaB in regulation of the shear stress-induced MMP-9 expression in endothelial cells. Biochem Biophys Res Commun (2006) 1.00
Acutely altered hemodynamics following venous obstruction in the early chick embryo. J Exp Biol (2003) 0.94
Arterial hemodynamics and mechanical properties after circulatory intervention in the chick embryo. J Exp Biol (2005) 0.93
Differential global gene expression response patterns of human endothelium exposed to shear stress and intraluminal pressure. J Vasc Res (2005) 0.89
Altered hemodynamics in chick embryos after extraembryonic venous obstruction. Ultrasound Obstet Gynecol (1999) 0.89
Ventricular diastolic filling characteristics in stage-24 chick embryos after extra-embryonic venous obstruction. J Exp Biol (2004) 0.88
Magnetic resonance microscopy at 17.6-Tesla on chicken embryos in vitro. J Magn Reson Imaging (2001) 0.88
Transforming growth factor beta-SMAD2 signaling and aortic arch development. Trends Cardiovasc Med (2006) 0.86
Dorsal aortic flow velocity in chick embryos of stage 16 to 28. Ultrasound Med Biol (2001) 0.82
Flow in the early embryonic human heart: a numerical study. Pediatr Cardiol (2003) 0.81
Quantifying cardiovascular flow dynamics during early development. Pediatr Res (2006) 0.81
The endothelin-1 pathway and the development of cardiovascular defects in the haemodynamically challenged chicken embryo. J Vasc Res (2007) 0.81
Systolic and diastolic ventricular function assessed by pressure-volume loops in the stage 21 venous clipped chick embryo. Pediatr Res (2004) 0.80
Epinephrine affects hemodynamics of noninnervated normal and all-trans retinoic acid-treated embryonic chick hearts. Fetal Diagn Ther (2004) 0.77
Graphical and stereolithographic models of the developing human heart lumen. Comput Med Imaging Graph (2001) 0.77
Fluid shear stress controls cardiovascular development. A functionomic approach. Wien Klin Wochenschr (2007) 0.77
Normal and abnormal development of pulmonary veins: state of the art and correlation with clinical entities. Int J Cardiol (2010) 2.78
Temporal and distinct TGFbeta ligand requirements during mouse and avian endocardial cushion morphogenesis. Dev Biol (2002) 2.61
Epicardium-derived cells in development of annulus fibrosis and persistence of accessory pathways. Circulation (2008) 1.96
Transforming growth factor beta in cardiovascular development and function. Cytokine Growth Factor Rev (2003) 1.84
VEGF: a modifier of the del22q11 (DiGeorge) syndrome? Nat Med (2003) 1.79
Targeted mutation reveals essential functions of the homeodomain transcription factor Shox2 in sinoatrial and pacemaking development. Circulation (2007) 1.72
Origin, fate, and function of epicardium-derived cells (EPDCs) in normal and abnormal cardiac development. ScientificWorldJournal (2007) 1.57
In vivo micro particle image velocimetry measurements of blood-plasma in the embryonic avian heart. J Biomech (2006) 1.53
Changes in shear stress-related gene expression after experimentally altered venous return in the chicken embryo. Circ Res (2005) 1.47
Subepicardial endothelial cells invade the embryonic ventricle wall to form coronary arteries. Cell Res (2013) 1.46
Nuchal edema and venous-lymphatic phenotype disturbance in human fetuses and mouse embryos with aneuploidy. J Soc Gynecol Investig (2006) 1.45
Epicardial cells of human adults can undergo an epithelial-to-mesenchymal transition and obtain characteristics of smooth muscle cells in vitro. Stem Cells (2006) 1.42
Monocilia on chicken embryonic endocardium in low shear stress areas. Dev Dyn (2006) 1.36
Endothelial primary cilia in areas of disturbed flow are at the base of atherosclerosis. Atherosclerosis (2007) 1.32
Lack of primary cilia primes shear-induced endothelial-to-mesenchymal transition. Circ Res (2011) 1.31
Expression patterns of Tgfbeta1-3 associate with myocardialisation of the outflow tract and the development of the epicardium and the fibrous heart skeleton. Dev Dyn (2003) 1.28
The alternatively spliced anti-angiogenic family of VEGF isoforms VEGFxxxb in human kidney development. Nephron Physiol (2008) 1.24
Development-related changes in the expression of shear stress responsive genes KLF-2, ET-1, and NOS-3 in the developing cardiovascular system of chicken embryos. Dev Dyn (2004) 1.24
Histological evaluation of decellularised porcine aortic valves: matrix changes due to different decellularisation methods. Eur J Cardiothorac Surg (2005) 1.21
The role of shear stress on ET-1, KLF2, and NOS-3 expression in the developing cardiovascular system of chicken embryos in a venous ligation model. Physiology (Bethesda) (2007) 1.21
Accurate blood flow measurements: are artificial tracers necessary? PLoS One (2012) 1.21
A new direction for cardiac regeneration therapy: application of synergistically acting epicardium-derived cells and cardiomyocyte progenitor cells. Circ Heart Fail (2009) 1.19
Ets-1 and Ets-2 transcription factors are essential for normal coronary and myocardial development in chicken embryos. Circ Res (2003) 1.12
Deficiency of the vestibular spine in atrioventricular septal defects in human fetuses with down syndrome. Am J Cardiol (2003) 1.10
Primary cilia as biomechanical sensors in regulating endothelial function. Differentiation (2011) 1.09
Coronary artery and orifice development is associated with proper timing of epicardial outgrowth and correlated Fas-ligand-associated apoptosis patterns. Circ Res (2005) 1.09
TGF-β signaling in endothelial-to-mesenchymal transition: the role of shear stress and primary cilia. Sci Signal (2012) 1.05
Funny current channel HCN4 delineates the developing cardiac conduction system in chicken heart. Heart Rhythm (2011) 1.04
Podoplanin deficient mice show a RhoA-related hypoplasia of the sinus venosus myocardium including the sinoatrial node. Dev Dyn (2009) 1.03
PDGF-B signaling is important for murine cardiac development: its role in developing atrioventricular valves, coronaries, and cardiac innervation. Dev Dyn (2008) 1.03
Altered apoptosis pattern during pharyngeal arch artery remodelling is associated with aortic arch malformations in Tgfbeta2 knock-out mice. Cardiovasc Res (2002) 1.01
Deciphering the endothelial shear stress sensor. Circulation (2008) 1.00
Tgfβ/Alk5 signaling is required for shear stress induced klf2 expression in embryonic endothelial cells. Dev Dyn (2011) 0.99
Pulmonary vein and atrial wall pathology in human total anomalous pulmonary venous connection. Int J Cardiol (2008) 0.99
Dysregulation of the PDGFRA gene causes inflow tract anomalies including TAPVR: integrating evidence from human genetics and model organisms. Hum Mol Genet (2010) 0.99
Insights into the pathogenesis and genetic background of patency of the ductus arteriosus. Neonatology (2009) 0.98
Periostin expression by epicardium-derived cells is involved in the development of the atrioventricular valves and fibrous heart skeleton. Differentiation (2008) 0.98
Non-invasive tracking of avian development in vivo by MRI. NMR Biomed (2009) 0.97
Mesenchymal stem cells from ischemic heart disease patients improve left ventricular function after acute myocardial infarction. Am J Physiol Heart Circ Physiol (2007) 0.97
Intrauterine exposure to maternal atherosclerotic risk factors increases the susceptibility to atherosclerosis in adult life. Arterioscler Thromb Vasc Biol (2007) 0.97
Transforming growth factor beta-SMAD2 signaling regulates aortic arch innervation and development. Circ Res (2004) 0.96
The neural crest is contiguous with the cardiac conduction system in the mouse embryo: a role in induction? Anat Embryol (Berl) (2004) 0.96
Histology of vascular myocardial wall of left atrial body after pulmonary venous incorporation. Am J Cardiol (2006) 0.95
Folic acid and homocysteine affect neural crest and neuroepithelial cell outgrowth and differentiation in vitro. Dev Dyn (2003) 0.95
Transcription factor Sp3 knockout mice display serious cardiac malformations. Mol Cell Biol (2007) 0.95
Endothelial colony-forming cells show a mature transcriptional response to shear stress. In Vitro Cell Dev Biol Anim (2011) 0.94
Acutely altered hemodynamics following venous obstruction in the early chick embryo. J Exp Biol (2003) 0.94
Persistence of functional atrioventricular accessory pathways in postseptated embryonic avian hearts: implications for morphogenesis and functional maturation of the cardiac conduction system. Circulation (2006) 0.93
Developmental coronary maturation is disturbed by aberrant cardiac vascular endothelial growth factor expression and Notch signalling. Cardiovasc Res (2007) 0.93
Chronic right ventricular pressure overload results in a hyperplastic rather than a hypertrophic myocardial response. J Anat (2008) 0.93
Platelet-derived growth factor is involved in the differentiation of second heart field-derived cardiac structures in chicken embryos. Dev Dyn (2009) 0.92
Left atrial tachycardia originating from the mitral annulus-aorta junction. Circulation (2004) 0.92
Pulmonary vein, dorsal atrial wall and atrial septum abnormalities in podoplanin knockout mice with disturbed posterior heart field contribution. Pediatr Res (2009) 0.91
Cardiac malformations in Pdgfralpha mutant embryos are associated with increased expression of WT1 and Nkx2.5 in the second heart field. Dev Dyn (2010) 0.91
Tetralogy of fallot and alterations in vascular endothelial growth factor-A signaling and notch signaling in mouse embryos solely expressing the VEGF120 isoform. Circ Res (2007) 0.90
The mechanosensory role of primary cilia in vascular hypertension. Int J Vasc Med (2011) 0.89
Development of the cardiac conduction system in atrioventricular septal defect in human trisomy 21. Pediatr Res (2005) 0.88
Differential temporal and spatial progerin expression during closure of the ductus arteriosus in neonates. PLoS One (2011) 0.88
The role of the epicardium and neural crest as extracardiac contributors to coronary vascular development. Tex Heart Inst J (2002) 0.88
Ventricular diastolic filling characteristics in stage-24 chick embryos after extra-embryonic venous obstruction. J Exp Biol (2004) 0.88
Epicardium-derived cells enhance proliferation, cellular maturation and alignment of cardiomyocytes. J Mol Cell Cardiol (2010) 0.88
The lim domain only protein 7 is important in zebrafish heart development. Dev Dyn (2008) 0.87
Jugular lymphatic maldevelopment in Turner syndrome and trisomy 21: different anomalies leading to nuchal edema. Reprod Sci (2008) 0.87
N-Acetylcysteine prevents congenital heart defects induced by pregestational diabetes. Cardiovasc Diabetol (2014) 0.87
Tapered microfluidic chip for the study of biochemical and mechanical response at subcellular level of endothelial cells to shear flow. Lab Chip (2009) 0.87
Cardiac outflow tract malformations in chick embryos exposed to homocysteine. Cardiovasc Res (2004) 0.87
A chicken model for DGCR6 as a modifier gene in the DiGeorge critical region. Pediatr Res (2004) 0.85
Role for primary cilia as flow detectors in the cardiovascular system. Int Rev Cell Mol Biol (2011) 0.85
Normal and abnormal development of the cardiac conduction system; implications for conduction and rhythm disorders in the child and adult. Differentiation (2012) 0.85
Nitric oxide synthase-3 deficiency results in hypoplastic coronary arteries and postnatal myocardial infarction. Eur Heart J (2012) 0.85
Apoptosis as an instrument in cardiovascular development. Birth Defects Res C Embryo Today (2005) 0.85
Bicuspid aortic valve morphology and associated cardiovascular abnormalities in fetal Turner syndrome: a pathomorphological study. Fetal Diagn Ther (2014) 0.83
Neo-coarctation after the arterial switch operation. Interact Cardiovasc Thorac Surg (2011) 0.83
The myth of ventrally emigrating neural tube (VENT) cells and their contribution to the developing cardiovascular system. Anat Embryol (Berl) (2003) 0.82
VEGF polymorphisms are associated with endocardial cushion defects: a family-based case-control study. Pediatr Res (2010) 0.82
Disturbed myocardial connexin 43 and N-cadherin expressions in hypoplastic left heart syndrome and borderline left ventricle. J Thorac Cardiovasc Surg (2012) 0.82
The endothelin-1 pathway and the development of cardiovascular defects in the haemodynamically challenged chicken embryo. J Vasc Res (2007) 0.81
Shear induced collateral artery growth modulated by endoglin but not by ALK1. J Cell Mol Med (2012) 0.81
Prenatal exposure to apoE deficiency and postnatal hypercholesterolemia are associated with altered cell-specific lysine methyltransferase and histone methylation patterns in the vasculature. Am J Pathol (2009) 0.81
Spatiotemporally separated cardiac neural crest subpopulations that target the outflow tract septum and pharyngeal arch arteries. Anat Rec A Discov Mol Cell Evol Biol (2003) 0.81
Functional attenuation of UFD1l, a 22q11.2 deletion syndrome candidate gene, leads to cardiac outflow septation defects in chicken embryos. Pediatr Res (2003) 0.81
Epithelial-to-mesenchymal transformation alters electrical conductivity of human epicardial cells. J Cell Mol Med (2011) 0.80
Maternal transmission of risk for atherosclerosis. Curr Opin Lipidol (2008) 0.80
Homocysteine induces endothelial cell detachment and vessel wall thickening during chick embryonic development. Circ Res (2003) 0.79
Pitx2: a challenging teenager. Circ Res (2008) 0.78
The development of the pulmonary vein revisited. Int J Cardiol (2011) 0.77
Aberrant lymphatic development in euploid fetuses with increased nuchal translucency including Noonan syndrome. Prenat Diagn (2011) 0.77
Abnormal Shh and FOXC2 expression correlates with aberrant lymphatic development in human fetuses with increased nuchal translucency. Prenat Diagn (2009) 0.76
Increased NCAM expression and vascular development in trisomy 16 mouse embryos: relationship with nuchal translucency. Pediatr Res (2005) 0.76
Cardiac birth defects. Differentiation (2012) 0.76
Connexin43 levels are increased in mouse neural crest cells exposed to homocysteine. Birth Defects Res A Clin Mol Teratol (2006) 0.75
Increased nuchal translucency is associated with jugular lymphatic distension. Hum Reprod (2002) 0.75
Temporal relationship between increased nuchal translucency and enlarged jugular lymphatic sac. Obstet Gynecol (2006) 0.75