Published in Arthritis Rheum on February 01, 2008
Mechanical injury and cytokines cause loss of cartilage integrity and upregulate proteins associated with catabolism, immunity, inflammation, and repair. Mol Cell Proteomics (2009) 1.19
A systems biology approach to synovial joint lubrication in health, injury, and disease. Wiley Interdiscip Rev Syst Biol Med (2011) 1.12
Pathogenetic mechanisms of posttraumatic osteoarthritis: opportunities for early intervention. Int J Clin Exp Med (2011) 1.01
Vimentin contributes to changes in chondrocyte stiffness in osteoarthritis. J Orthop Res (2011) 1.00
The ECM-cell interaction of cartilage extracellular matrix on chondrocytes. Biomed Res Int (2014) 0.97
High throughput proteomic analysis of the secretome in an explant model of articular cartilage inflammation. J Proteomics (2011) 0.97
Interleukin-1 beta and tumor necrosis factor alpha inhibit migration activity of chondrogenic progenitor cells from non-fibrillated osteoarthritic cartilage. Arthritis Res Ther (2013) 0.93
Carprofen inhibits the release of matrix metalloproteinases 1, 3, and 13 in the secretome of an explant model of articular cartilage stimulated with interleukin 1β. Arthritis Res Ther (2013) 0.93
Hepatitis C virus mediated changes in miRNA-449a modulates inflammatory biomarker YKL40 through components of the NOTCH signaling pathway. PLoS One (2012) 0.91
Application for proteomic techniques in studying osteoarthritis: a review. Front Physiol (2011) 0.90
Absolute quantification of selected proteins in the human osteoarthritic secretome. Int J Mol Sci (2013) 0.89
Joint aging and chondrocyte cell death. Int J Clin Rheumtol (2010) 0.86
Applications of proteomics to osteoarthritis, a musculoskeletal disease characterized by aging. Front Physiol (2011) 0.83
Alterations in the red blood cell membrane proteome in alzheimer's subjects reflect disease-related changes and provide insight into altered cell morphology. Proteome Sci (2010) 0.81
A proteomic approach for identification and localization of the pericellular components of chondrocytes. Histochem Cell Biol (2011) 0.81
Biomarkers of Chondrocyte Apoptosis and Autophagy in Osteoarthritis. Int J Mol Sci (2015) 0.80
Proteomic analysis of synovial fluid as an analytical tool to detect candidate biomarkers for knee osteoarthritis. Int J Clin Exp Pathol (2015) 0.76
Structural and thermodynamic insights into chitooligosaccharide binding to human cartilage chitinase 3-like protein 2 (CHI3L2 or YKL-39). J Biol Chem (2014) 0.75
Compression loading-induced stress responses in intervertebral disc cells encapsulated in 3D collagen constructs. Sci Rep (2016) 0.75
Proteomic Analysis of Engineered Cartilage. Methods Mol Biol (2015) 0.75
The Effects of Ferulic Acid Against Oxidative Stress and Inflammation in Formaldehyde-Induced Hepatotoxicity. Inflammation (2016) 0.75
Characterization of the chondrocyte secretome in photoclickable poly(ethylene glycol) hydrogels. Biotechnol Bioeng (2017) 0.75
Local myocardial insulin-like growth factor 1 (IGF-1) delivery with biotinylated peptide nanofibers improves cell therapy for myocardial infarction. Proc Natl Acad Sci U S A (2006) 2.75
A patterned anisotropic nanofluidic sieving structure for continuous-flow separation of DNA and proteins. Nat Nanotechnol (2007) 2.66
Phosphorothioation of DNA in bacteria by dnd genes. Nat Chem Biol (2007) 2.57
Articular cartilage and osteoarthritis. Instr Course Lect (2005) 2.39
Reactive nitrogen species in the chemical biology of inflammation. Arch Biochem Biophys (2004) 2.24
AlkB reverses etheno DNA lesions caused by lipid oxidation in vitro and in vivo. Nat Struct Mol Biol (2005) 1.96
Mechanical injury of cartilage explants causes specific time-dependent changes in chondrocyte gene expression. Arthritis Rheum (2005) 1.94
The hydantoin lesions formed from oxidation of 7,8-dihydro-8-oxoguanine are potent sources of replication errors in vivo. Biochemistry (2003) 1.92
Individual cartilage aggrecan macromolecules and their constituent glycosaminoglycans visualized via atomic force microscopy. J Struct Biol (2003) 1.92
Single dose pharmacokinetics of oral tenofovir in plasma, peripheral blood mononuclear cells, colonic tissue, and vaginal tissue. AIDS Res Hum Retroviruses (2013) 1.76
Infection-induced colitis in mice causes dynamic and tissue-specific changes in stress response and DNA damage leading to colon cancer. Proc Natl Acad Sci U S A (2012) 1.67
The rational design of nitric oxide selectivity in single-walled carbon nanotube near-infrared fluorescence sensors for biological detection. Nat Chem (2009) 1.64
Custom design of the cardiac microenvironment with biomaterials. Circ Res (2005) 1.63
Proteoglycan degradation after injurious compression of bovine and human articular cartilage in vitro: interaction with exogenous cytokines. Arthritis Rheum (2003) 1.59
Integration of continuous-flow accelerator mass spectrometry with chromatography and mass-selective detection. Anal Chem (2008) 1.57
Mechanical compression of cartilage explants induces multiple time-dependent gene expression patterns and involves intracellular calcium and cyclic AMP. J Biol Chem (2004) 1.56
Lipid peroxidation dominates the chemistry of DNA adduct formation in a mouse model of inflammation. Carcinogenesis (2007) 1.55
Oxidation of 7,8-dihydro-8-oxoguanine affords lesions that are potent sources of replication errors in vivo. Biochemistry (2002) 1.48
Global phosphoproteome of HT-29 human colon adenocarcinoma cells. J Proteome Res (2005) 1.46
Evaluation of adult equine bone marrow- and adipose-derived progenitor cell chondrogenesis in hydrogel cultures. J Orthop Res (2008) 1.43
Onset of preclinical osteoarthritis: the angular spatial organization permits early diagnosis. Arthritis Rheum (2011) 1.43
Compressive nanomechanics of opposing aggrecan macromolecules. J Biomech (2005) 1.41
Arsenic exposure perturbs the gut microbiome and its metabolic profile in mice: an integrated metagenomics and metabolomics analysis. Environ Health Perspect (2014) 1.41
Influence of tissue maturation and antioxidants on the apoptotic response of articular cartilage after injurious compression. Arthritis Rheum (2004) 1.38
Effects of dynamic compressive loading on chondrocyte biosynthesis in self-assembling peptide scaffolds. J Biomech (2004) 1.37
Gene expression profiles of human chondrocytes during passaged monolayer cultivation. J Orthop Res (2008) 1.36
Pathomechanisms of cartilage destruction by mechanical injury. Ann Anat (2005) 1.31
Mechanical injury potentiates proteoglycan catabolism induced by interleukin-6 with soluble interleukin-6 receptor and tumor necrosis factor alpha in immature bovine and adult human articular cartilage. Arthritis Rheum (2009) 1.27
Three-dimensional head model simulation of transcranial magnetic stimulation. IEEE Trans Biomed Eng (2004) 1.23
PGE2-regulated wnt signaling and N-acetylcysteine are synergistically hepatoprotective in zebrafish acetaminophen injury. Proc Natl Acad Sci U S A (2010) 1.21
Shear and compression differentially regulate clusters of functionally related temporal transcription patterns in cartilage tissue. J Biol Chem (2006) 1.21
Arylamine exposures and bladder cancer risk. Mutat Res (2002) 1.20
Peroxynitrite-induced oxidation and nitration products of guanine and 8-oxoguanine: structures and mechanisms of product formation. Nitric Oxide (2005) 1.19
Mechanical regulation of mitogen-activated protein kinase signaling in articular cartilage. J Biol Chem (2003) 1.19
Effects of short-term glucocorticoid treatment on changes in cartilage matrix degradation and chondrocyte gene expression induced by mechanical injury and inflammatory cytokines. Arthritis Res Ther (2011) 1.19
Mechanical injury and cytokines cause loss of cartilage integrity and upregulate proteins associated with catabolism, immunity, inflammation, and repair. Mol Cell Proteomics (2009) 1.19
An interface for direct analysis of (14)c in nonvolatile samples by accelerator mass spectrometry. Anal Chem (2004) 1.18
Mechanical overload induces VEGF in cartilage discs via hypoxia-inducible factor. Am J Pathol (2004) 1.18
Liver tissue engineering in the evaluation of drug safety. Expert Opin Drug Metab Toxicol (2009) 1.17
Shear- and compression-induced chondrocyte transcription requires MAPK activation in cartilage explants. J Biol Chem (2007) 1.15
S-Nitrosation regulates the activation of endogenous procaspase-9 in HT-29 human colon carcinoma cells. J Biol Chem (2003) 1.15
Serum proteome and cytokine analysis in a longitudinal cohort of adults with primary dengue infection reveals predictive markers of DHF. PLoS Negl Trop Dis (2012) 1.14
Alkylaniline-hemoglobin adducts and risk of non-smoking-related bladder cancer. J Natl Cancer Inst (2004) 1.14
Mechanisms and kinetics of glycosaminoglycan release following in vitro cartilage injury. Arthritis Rheum (2004) 1.11
Increase of reaction rate and sensitivity of low-abundance enzyme assay using micro/nanofluidic preconcentration chip. Anal Chem (2008) 1.11
Nonsmoking-related arylamine exposure and bladder cancer risk. Cancer Epidemiol Biomarkers Prev (2003) 1.09
Transport and binding of insulin-like growth factor I through articular cartilage. Arch Biochem Biophys (2003) 1.09
Lateral nanomechanics of cartilage aggrecan macromolecules. Biophys J (2006) 1.08
Evaluation of medium supplemented with insulin-transferrin-selenium for culture of primary bovine calf chondrocytes in three-dimensional hydrogel scaffolds. Tissue Eng (2005) 1.08
Modulation of lubricin biosynthesis and tissue surface properties following cartilage mechanical injury. Arthritis Rheum (2009) 1.08
Chondrocyte mechanotransduction: effects of compression on deformation of intracellular organelles and relevance to cellular biosynthesis. Osteoarthritis Cartilage (2004) 1.08
Time-dependent nanomechanics of cartilage. Biophys J (2011) 1.07
Dynamic compression stimulates proteoglycan synthesis by mesenchymal stem cells in the absence of chondrogenic cytokines. Tissue Eng Part A (2009) 1.05
Spiroiminodihydantoin and guanidinohydantoin are the dominant products of 8-oxoguanosine oxidation at low fluxes of peroxynitrite: mechanistic studies with 18O. Chem Res Toxicol (2004) 1.04
Quantitation of four guanine oxidation products from reaction of DNA with varying doses of peroxynitrite. Chem Res Toxicol (2005) 1.04
Environmental tobacco smoke and bladder cancer risk in never smokers of Los Angeles County. Cancer Res (2007) 1.04
Gut microbiome perturbations induced by bacterial infection affect arsenic biotransformation. Chem Res Toxicol (2013) 1.04
A coarse-grained molecular model for glycosaminoglycans: application to chondroitin, chondroitin sulfate, and hyaluronic acid. Biophys J (2005) 1.02
Covalent adducts arising from the decomposition products of lipid hydroperoxides in the presence of cytochrome c. Chem Res Toxicol (2007) 1.01
Biphasic elimination of tenofovir diphosphate and nonlinear pharmacokinetics of zidovudine triphosphate in a microdosing study. J Acquir Immune Defic Syndr (2012) 1.01
Site-specific and redox-controlled S-nitrosation of thioredoxin. Proc Natl Acad Sci U S A (2011) 1.01
Relevance of collagen piezoelectricity to "Wolff's Law": a critical review. Med Eng Phys (2009) 1.00
Analysis of nitrated proteins by nitrotyrosine-specific affinity probes and mass spectrometry. Anal Biochem (2003) 0.99
Serum metabolome and lipidome changes in adult patients with primary dengue infection. PLoS Negl Trop Dis (2013) 0.99
Detection and quantification of 4-ABP adducts in DNA from bladder cancer patients. Carcinogenesis (2006) 0.98
Characterization of testosterone 11 beta-hydroxylation catalyzed by human liver microsomal cytochromes P450. Drug Metab Dispos (2005) 0.97
Self-assembling peptide hydrogels modulate in vitro chondrogenesis of bovine bone marrow stromal cells. Tissue Eng Part A (2010) 0.97
Chemical and cytokine features of innate immunity characterize serum and tissue profiles in inflammatory bowel disease. Proc Natl Acad Sci U S A (2013) 0.97
Mechanical motion promotes expression of Prg4 in articular cartilage via multiple CREB-dependent, fluid flow shear stress-induced signaling pathways. Genes Dev (2014) 0.97
Vulnerability of the superficial zone of immature articular cartilage to compressive injury. Arthritis Rheum (2010) 0.97
Renal injury is a consistent finding in Dutch Belted rabbits experimentally infected with enterohemorrhagic Escherichia coli. J Infect Dis (2006) 0.97
Intraarticular injection of heparin-binding insulin-like growth factor 1 sustains delivery of insulin-like growth factor 1 to cartilage through binding to chondroitin sulfate. Arthritis Rheum (2010) 0.96
Mechanism-based triarylphosphine-ester probes for capture of endogenous RSNOs. J Am Chem Soc (2013) 0.96
DNA adducts formed by a novel antitumor agent 11beta-dichloro in vitro and in vivo. Mol Cancer Ther (2006) 0.95
Preservation and analysis of nonequilibrium solute concentration distributions within mechanically compressed cartilage explants. J Biochem Biophys Methods (2002) 0.95
Metabolomics reveals altered metabolic pathways in experimental asthma. Am J Respir Cell Mol Biol (2012) 0.95
Serum metabolomics in a Helicobacter hepaticus mouse model of inflammatory bowel disease reveal important changes in the microbiome, serum peptides, and intermediary metabolism. J Proteome Res (2012) 0.95
Quantification of DNA strand breaks and abasic sites by oxime derivatization and accelerator mass spectrometry: application to gamma-radiation and peroxynitrite. Anal Biochem (2005) 0.94
Nanomechanics of opposing glycosaminoglycan macromolecules. J Biomech (2005) 0.94