Published in Physiol Behav on November 22, 2007
Early life programming and neurodevelopmental disorders. Biol Psychiatry (2010) 2.93
Obesity and leptin resistance: distinguishing cause from effect. Trends Endocrinol Metab (2010) 2.79
Maternal high-fat diet and fetal programming: increased proliferation of hypothalamic peptide-producing neurons that increase risk for overeating and obesity. J Neurosci (2008) 1.96
Tanycytes of the hypothalamic median eminence form a diet-responsive neurogenic niche. Nat Neurosci (2012) 1.89
Bisphenol A: Perinatal exposure and body weight. Mol Cell Endocrinol (2009) 1.82
Metabolic imprinting in obesity. Forum Nutr (2009) 1.58
Perinatal exposure to high-fat diet programs energy balance, metabolism and behavior in adulthood. Neuroendocrinology (2010) 1.56
Influence of pre- and peri-natal nutrition on skeletal acquisition and maintenance. Bone (2011) 1.45
Neonatal leptin exposure specifies innervation of presympathetic hypothalamic neurons and improves the metabolic status of leptin-deficient mice. J Neurosci (2013) 1.03
Maternal high fat diet consumption during the perinatal period programs offspring behavior. Physiol Behav (2012) 0.96
Gamma-protocadherins regulate the functional integrity of hypothalamic feeding circuitry in mice. Dev Biol (2009) 0.93
Maternal high-fat diet programming of the neuroendocrine system and behavior. Horm Behav (2015) 0.91
Unraveling the mechanisms responsible for the comorbidity between metabolic syndrome and mental health disorders. Neuroendocrinology (2013) 0.83
Major epigenetic development distinguishing neuronal and non-neuronal cells occurs postnatally in the murine hypothalamus. Hum Mol Genet (2013) 0.82
Leptin signaling modulates the activity of urocortin 1 neurons in the mouse nonpreganglionic Edinger-Westphal nucleus. Endocrinology (2011) 0.82
Role of various neurotransmitters in mediating the long-term endocrine consequences of prenatal alcohol exposure. Ann N Y Acad Sci (2008) 0.81
Developmental specification of metabolic circuitry. Front Neuroendocrinol (2015) 0.79
Purdue Ingestive Behavior Research Center symposium 2007: influences on eating and body weight over the lifespan--childhood and adolescence. Physiol Behav (2007) 0.78
The Impact of Maternal High-Fat Diet Consumption on Neural Development and Behavior of Offspring. Int J Obes Suppl (2015) 0.77
Early postnatal overnutrition: potential roles of gastrointestinal vagal afferents and brain-derived neurotrophic factor. Physiol Behav (2012) 0.77
The neuroendocrinology and neuroscience of energy balance. Front Neuroendocrinol (2009) 0.76
Meal parameters and vagal gastrointestinal afferents in mice that experienced early postnatal overnutrition. Physiol Behav (2010) 0.76
Interaction between neonatal maternal deprivation and serum leptin levels on metabolism, pubertal development, and sexual behavior in male and female rats. Biol Sex Differ (2016) 0.75
Maternal protein restriction during lactation modulated the expression and activity of rat offspring hepatic CYP1A1, CYP1A2, CYP2B1, CYP2B2, and CYP2E1 during development. Braz J Med Biol Res (2016) 0.75
Prevalence and trends in overweight among US children and adolescents, 1999-2000. JAMA (2002) 23.79
Central nervous system control of food intake. Nature (2000) 15.85
Leptin and the regulation of body weight in mammals. Nature (1998) 14.84
Congenital leptin deficiency is associated with severe early-onset obesity in humans. Nature (1997) 7.33
Leptin receptor signaling in POMC neurons is required for normal body weight homeostasis. Neuron (2004) 7.15
Anatomy and regulation of the central melanocortin system. Nat Neurosci (2005) 6.60
Rapid rewiring of arcuate nucleus feeding circuits by leptin. Science (2004) 5.98
Trophic action of leptin on hypothalamic neurons that regulate feeding. Science (2004) 5.76
Leptin receptor signaling in midbrain dopamine neurons regulates feeding. Neuron (2006) 5.64
Mosaic organization of neural stem cells in the adult brain. Science (2007) 5.05
The need to feed: homeostatic and hedonic control of eating. Neuron (2002) 4.99
Leptin activation of Stat3 in the hypothalamus of wild-type and ob/ob mice but not db/db mice. Nat Genet (1996) 4.84
Critical periods in childhood for the development of obesity. Am J Clin Nutr (1994) 4.66
Diabetes, obesity, and the brain. Science (2005) 4.59
Leptin regulation of the mesoaccumbens dopamine pathway. Neuron (2006) 4.53
Distributions of leptin receptor mRNA isoforms in the rat brain. J Comp Neurol (1998) 4.30
Mammalian hibernation: cellular and molecular responses to depressed metabolism and low temperature. Physiol Rev (2003) 4.29
From lesions to leptin: hypothalamic control of food intake and body weight. Neuron (1999) 4.18
Neurogenesis in the hypothalamus of adult mice: potential role in energy balance. Science (2005) 4.01
Hypothalamic integration: organization of the paraventricular and supraoptic nuclei. Annu Rev Neurosci (1983) 3.98
Cerebral hemisphere regulation of motivated behavior. Brain Res (2000) 3.53
Fetal origins of hyperphagia, obesity, and hypertension and postnatal amplification by hypercaloric nutrition. Am J Physiol Endocrinol Metab (2000) 3.52
Neonatal leptin treatment reverses developmental programming. Endocrinology (2005) 3.51
Postnatal development of the visual cortex and the influence of environment. Nature (1982) 3.50
Identification of targets of leptin action in rat hypothalamus. J Clin Invest (1996) 3.49
The hypothalamic arcuate nucleus: a key site for mediating leptin's effects on glucose homeostasis and locomotor activity. Cell Metab (2005) 3.38
Brain lesions, obesity, and other disturbances in mice treated with monosodium glutamate. Science (1969) 3.08
Fos expression in orexin neurons varies with behavioral state. J Neurosci (2001) 3.08
Chemically defined projections linking the mediobasal hypothalamus and the lateral hypothalamic area. J Comp Neurol (1998) 3.01
Potential mechanisms of metabolic imprinting that lead to chronic disease. Am J Clin Nutr (1999) 2.98
The neuropeptide Y/agouti gene-related protein (AGRP) brain circuitry in normal, anorectic, and monosodium glutamate-treated mice. Proc Natl Acad Sci U S A (1998) 2.91
Insulin activation of phosphatidylinositol 3-kinase in the hypothalamic arcuate nucleus: a key mediator of insulin-induced anorexia. Diabetes (2003) 2.90
Glucocorticoid programming. Ann N Y Acad Sci (2004) 2.73
Anorectic estrogen mimics leptin's effect on the rewiring of melanocortin cells and Stat3 signaling in obese animals. Nat Med (2006) 2.72
Leptin receptor signaling and the regulation of mammalian physiology. Recent Prog Horm Res (2004) 2.67
Hypothalamic sensing of fatty acids. Nat Neurosci (2005) 2.67
An autoradiographic analysis of the differential ascending projections of the dorsal and median raphe nuclei in the rat. J Comp Neurol (1978) 2.63
Anatomic localization of alternatively spliced leptin receptors (Ob-R) in mouse brain and other tissues. Proc Natl Acad Sci U S A (1997) 2.57
Formation of projection pathways from the arcuate nucleus of the hypothalamus to hypothalamic regions implicated in the neural control of feeding behavior in mice. J Neurosci (2004) 2.37
Topographic mapping of VMH --> arcuate nucleus microcircuits and their reorganization by fasting. Nat Neurosci (2005) 2.29
Minireview: From anorexia to obesity--the yin and yang of body weight control. Endocrinology (2003) 2.27
Postnatal leptin surge and regulation of circadian rhythm of leptin by feeding. Implications for energy homeostasis and neuroendocrine function. J Clin Invest (1998) 2.23
The neuroanatomical axis for control of energy balance. Front Neuroendocrinol (2002) 2.12
Brain regulation of food intake and appetite: molecules and networks. J Intern Med (2005) 2.11
Unraveling the central nervous system pathways underlying responses to leptin. Nat Neurosci (1998) 2.08
The organization of forebrain afferents to the paraventricular and supraoptic nuclei of the rat. J Comp Neurol (1983) 2.03
Leptin receptor immunoreactivity in chemically defined target neurons of the hypothalamus. J Neurosci (1998) 2.01
Connections of the rat lateral septal complex. Brain Res Brain Res Rev (1997) 2.00
Anatomical evidence of direct projections from the nucleus of the solitary tract to the hypothalamus, amygdala, and other forebrain structures in the rat. Brain Res (1978) 1.99
Arcuate nucleus-specific leptin receptor gene therapy attenuates the obesity phenotype of Koletsky (fa(k)/fa(k)) rats. Endocrinology (2003) 1.99
Leptin signaling. Physiol Behav (2004) 1.93
Leptin activates distinct projections from the dorsomedial and ventromedial hypothalamic nuclei. Proc Natl Acad Sci U S A (1998) 1.92
Minireview: ghrelin and the regulation of energy balance--a hypothalamic perspective. Endocrinology (2001) 1.92
The fetal and infant origins of disease. Eur J Clin Invest (1995) 1.88
Regulation of neuronal and glial proteins by leptin: implications for brain development. Endocrinology (1999) 1.87
Maternal programming of steroid receptor expression and phenotype through DNA methylation in the rat. Front Neuroendocrinol (2005) 1.87
The influence of birthweight and intrauterine environment on adiposity and fat distribution in later life. Int J Obes Relat Metab Disord (2003) 1.84
Role of premature leptin surge in obesity resulting from intrauterine undernutrition. Cell Metab (2005) 1.83
Leptin activates neurons in ventrobasal hypothalamus and brainstem. Endocrinology (1997) 1.81
Projections of the medial preoptic nucleus: a Phaseolus vulgaris leucoagglutinin anterograde tract-tracing study in the rat. J Comp Neurol (1988) 1.79
Heterogeneity in the neuropeptide Y-containing neurons of the rat arcuate nucleus: GABAergic and non-GABAergic subpopulations. Brain Res (1997) 1.75
Metabolic imprinting: critical impact of the perinatal environment on the regulation of energy homeostasis. Philos Trans R Soc Lond B Biol Sci (2006) 1.72
Time of neuron origin in mouse hypothalamic nuclei. Exp Neurol (1973) 1.66
Pediatric obesity and insulin resistance: chronic disease risk and implications for treatment and prevention beyond body weight modification. Annu Rev Nutr (2005) 1.64
The structural organization of connections between hypothalamus and cerebral cortex. Brain Res Brain Res Rev (1997) 1.64
The dorsomedial hypothalamic nucleus and its role in ingestive behavior and body weight regulation: lessons learned from lesioning studies. Physiol Behav (2002) 1.55
Organization of inputs to the dorsomedial nucleus of the hypothalamus: a reexamination with Fluorogold and PHAL in the rat. Brain Res Brain Res Rev (1998) 1.55
Perinatal nutrition and hormone-dependent programming of food intake. Horm Res (2006) 1.54
Obesity and adipocyte abnormalities in offspring of rats undernourished during pregnancy. Science (1982) 1.47
Childhood obesity in Canada: a review of prevalence estimates and risk factors for cardiovascular diseases and type 2 diabetes. Can J Appl Physiol (2003) 1.47
Effect of intracerebroventricular insulin infusion on diabetic hyperphagia and hypothalamic neuropeptide gene expression. Diabetes (1995) 1.44
Organization of projections from the dorsomedial nucleus of the hypothalamus: a PHA-L study in the rat. J Comp Neurol (1996) 1.43
Development of metabolic systems. Physiol Behav (2005) 1.43
Comparison of melanin-concentrating hormone and hypocretin/orexin mRNA expression patterns in a new parceling scheme of the lateral hypothalamic zone. Neurosci Lett (2005) 1.42
Melanin-concentrating hormone is a critical mediator of the leptin-deficient phenotype. Proc Natl Acad Sci U S A (2003) 1.41
Toward a new neurobiology of energy balance, appetite, and obesity: the anatomists weigh in. J Comp Neurol (1998) 1.40
The development of the rat hypothalamus. Adv Anat Embryol Cell Biol (1986) 1.39
The floating blueprint of hypothalamic feeding circuits. Nat Rev Neurosci (2004) 1.36
Early origins of obesity: programming the appetite regulatory system. J Physiol (2005) 1.35
Induction of neuropeptide Y gene expression in the dorsal medial hypothalamic nucleus in two models of the agouti obesity syndrome. Mol Endocrinol (1997) 1.34
Early programming of glucose-insulin metabolism. Trends Endocrinol Metab (2002) 1.34
Structural characterization of a hypothalamic visceromotor pattern generator network. Brain Res Brain Res Rev (2003) 1.33
Leptin: a diverse regulator of neuronal function. J Neurochem (2006) 1.32
Ontogeny of the hypothalamic neuropeptide Y system. Physiol Behav (2003) 1.32
Connections of the posterior nucleus of the amygdala. J Comp Neurol (1992) 1.32
Leptin-induced nuclear translocation of STAT3 immunoreactivity in hypothalamic nuclei involved in body weight regulation. J Neurosci (2001) 1.28
Effects of selective estrogen receptor agonists on food intake and body weight gain in rats. Physiol Behav (2005) 1.27
Ascending projections of the locus coeruleus in the rat. II. Autoradiographic study. Brain Res (1977) 1.26
An arcuato-paraventricular and -dorsomedial hypothalamic neuropeptide Y-containing system which lacks noradrenaline in the rat. Brain Res (1985) 1.25
Minireview: Leptin and development of hypothalamic feeding circuits. Endocrinology (2004) 1.25
Postnatal development of the hypothalamic neuropeptide Y system. Neuroscience (2003) 1.24
An autoradiographic study of the time of final division of neurons in rat hypothalamic nuclei. J Comp Neurol (1972) 1.23
Plasma membrane and vesicular glutamate transporter mRNAs/proteins in hypothalamic neurons that regulate body weight. Eur J Neurosci (2003) 1.20
Perinatal programming and functional teratogenesis: impact on body weight regulation and obesity. Physiol Behav (2005) 1.18
Leptin increases axonal growth cone size in developing mouse cortical neurons by convergent signals inactivating glycogen synthase kinase-3beta. J Biol Chem (2006) 1.18
Poor fetal growth followed by rapid postnatal catch-up growth leads to premature death. Mech Ageing Dev (2005) 1.18
Projections of the ventral premammillary nucleus. J Comp Neurol (1992) 1.16
Leptin alters metabolic rates before acquisition of its anorectic effect in developing neonatal mice. Am J Physiol (1999) 1.15
Understanding the neural control of ingestive behaviors: helping to separate cause from effect with dehydration-associated anorexia. Horm Behav (2000) 1.15
The electrophysiology of feeding circuits. Trends Endocrinol Metab (2004) 1.14