PubRank

Nico Van Rooijen

Author PubWeight™ 172.43‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Subpopulations of mouse blood monocytes differ in maturation stage and inflammatory response. J Immunol 2004 8.65
2 Chitin induces accumulation in tissue of innate immune cells associated with allergy. Nature 2007 5.82
3 Pathogenicity of influenza viruses with genes from the 1918 pandemic virus: functional roles of alveolar macrophages and neutrophils in limiting virus replication and mortality in mice. J Virol 2005 4.72
4 NF-kappaB is a negative regulator of IL-1beta secretion as revealed by genetic and pharmacological inhibition of IKKbeta. Cell 2007 4.56
5 Memory T(H)2 cells induce alternatively activated macrophages to mediate protection against nematode parasites. Nat Med 2006 4.16
6 Control of TH17 cells occurs in the small intestine. Nature 2011 4.03
7 Macrophage-derived Wnt opposes Notch signaling to specify hepatic progenitor cell fate in chronic liver disease. Nat Med 2012 3.96
8 Inflammation-induced lymphangiogenesis in the cornea arises from CD11b-positive macrophages. J Clin Invest 2005 3.77
9 Ly6c+ "inflammatory monocytes" are microglial precursors recruited in a pathogenic manner in West Nile virus encephalitis. J Exp Med 2008 3.08
10 Mucosal damage and neutropenia are required for Candida albicans dissemination. PLoS Pathog 2008 2.80
11 An essential role for TH2-type responses in limiting acute tissue damage during experimental helminth infection. Nat Med 2012 2.60
12 Phagocyte-derived catecholamines enhance acute inflammatory injury. Nature 2007 2.56
13 Protective influenza-specific CD8 T cell responses require interactions with dendritic cells in the lungs. J Exp Med 2008 2.55
14 Alum induces innate immune responses through macrophage and mast cell sensors, but these sensors are not required for alum to act as an adjuvant for specific immunity. J Immunol 2009 2.47
15 Monocyte chemoattractant protein-1 regulation of blood-brain barrier permeability. J Cereb Blood Flow Metab 2005 2.45
16 Macrophages prevent human red blood cell reconstitution in immunodeficient mice. Blood 2011 2.24
17 Mouse and human neutrophils induce anaphylaxis. J Clin Invest 2011 2.21
18 The Ly-6Chigh monocyte subpopulation transports Listeria monocytogenes into the brain during systemic infection of mice. J Immunol 2004 2.07
19 Macrophages and skeletal muscle regeneration: a clodronate-containing liposome depletion study. Am J Physiol Regul Integr Comp Physiol 2006 1.94
20 Roles of macrophages and neutrophils in the early host response to Bacillus anthracis spores in a mouse model of infection. Infect Immun 2006 1.93
21 Macrophages support pathological erythropoiesis in polycythemia vera and β-thalassemia. Nat Med 2013 1.89
22 Lung interstitial macrophages alter dendritic cell functions to prevent airway allergy in mice. J Clin Invest 2009 1.87
23 Umbilical cord blood regulatory T-cell expansion and functional effects of tumor necrosis factor receptor family members OX40 and 4-1BB expressed on artificial antigen-presenting cells. Blood 2008 1.80
24 Universal vaccine based on ectodomain of matrix protein 2 of influenza A: Fc receptors and alveolar macrophages mediate protection. J Immunol 2010 1.79
25 Respiratory syncytial virus-induced activation of nuclear factor-kappaB in the lung involves alveolar macrophages and toll-like receptor 4-dependent pathways. J Infect Dis 2002 1.77
26 Adenovirus vector-induced innate inflammatory mediators, MAPK signaling, as well as adaptive immune responses are dependent upon both TLR2 and TLR9 in vivo. J Immunol 2008 1.76
27 Osteal macrophages promote in vivo intramembranous bone healing in a mouse tibial injury model. J Bone Miner Res 2011 1.76
28 WNT signaling drives cholangiocarcinoma growth and can be pharmacologically inhibited. J Clin Invest 2015 1.68
29 In vitro-derived alternatively activated macrophages reduce colonic inflammation in mice. Gastroenterology 2010 1.61
30 Activated macrophages are essential in a murine model for T cell-mediated chronic psoriasiform skin inflammation. J Clin Invest 2006 1.58
31 Lack of CD47 on nonhematopoietic cells induces split macrophage tolerance to CD47null cells. Proc Natl Acad Sci U S A 2007 1.58
32 C5a initiates the inflammatory cascade in immune complex peritonitis. J Immunol 2004 1.57
33 Role of T cells in innate and adaptive immunity against murine Burkholderia pseudomallei infection. J Infect Dis 2005 1.56
34 The EGF/CSF-1 paracrine invasion loop can be triggered by heregulin beta1 and CXCL12. Cancer Res 2009 1.56
35 Inescapable need for neutrophils as mediators of cellular innate immunity to acute Pseudomonas aeruginosa pneumonia. Infect Immun 2009 1.52
36 IL-15 trans-presentation by pulmonary dendritic cells promotes effector CD8 T cell survival during influenza virus infection. J Exp Med 2010 1.52
37 Macrophages mediate inflammation-enhanced metastasis of ovarian tumors in mice. Cancer Res 2007 1.50
38 Type I IFNs enhance susceptibility to Chlamydia muridarum lung infection by enhancing apoptosis of local macrophages. J Immunol 2008 1.49
39 Naïve CD8 T cell activation by liver bone marrow-derived cells leads to a "neglected" IL-2low Bimhigh phenotype, poor CTL function and cell death. J Hepatol 2012 1.48
40 Mannose receptor expression specifically reveals perivascular macrophages in normal, injured, and diseased mouse brain. Glia 2005 1.42
41 Influenza virus-like particles containing M2 induce broadly cross protective immunity. PLoS One 2011 1.40
42 ICAM-1 triggers liver regeneration through leukocyte recruitment and Kupffer cell-dependent release of TNF-alpha/IL-6 in mice. Gastroenterology 2003 1.37
43 Extratumoral macrophages promote tumor and vascular growth in an orthotopic rat prostate tumor model. Neoplasia 2009 1.33
44 Tissue macrophages suppress viral replication and prevent severe immunopathology in an interferon-I-dependent manner in mice. Hepatology 2010 1.33
45 Neutrophil depletion causes a fatal defect in murine pulmonary Staphylococcus aureus clearance. J Surg Res 2008 1.30
46 Glycolipid presentation to natural killer T cells differs in an organ-dependent fashion. Proc Natl Acad Sci U S A 2005 1.29
47 The mechanism of anti-CD20-mediated B cell depletion revealed by intravital imaging. J Clin Invest 2013 1.27
48 Evasion by stealth: inefficient immune activation underlies poor T cell response and severe disease in SARS-CoV-infected mice. PLoS Pathog 2009 1.24
49 Antiglioma immunological memory in response to conditional cytotoxic/immune-stimulatory gene therapy: humoral and cellular immunity lead to tumor regression. Clin Cancer Res 2009 1.24
50 Vaccination inducing broad and improved cross protection against multiple subtypes of influenza A virus. Proc Natl Acad Sci U S A 2010 1.22
51 Early activation of the alveolar macrophage is critical to the development of lung ischemia-reperfusion injury. J Thorac Cardiovasc Surg 2003 1.22
52 A hemodynamic response to intravenous adenovirus vector particles is caused by systemic Kupffer cell-mediated activation of endothelial cells. Hum Gene Ther 2003 1.22
53 Modulation of macrophage activation state protects tissue from necrosis during critical limb ischemia in thrombospondin-1-deficient mice. PLoS One 2008 1.21
54 Liver-stage development of Plasmodium falciparum, in a humanized mouse model. J Infect Dis 2006 1.21
55 Stat3 activation in acute lung injury. J Immunol 2004 1.18
56 Urokinase-type plasminogen activator plays essential roles in macrophage chemotaxis and skeletal muscle regeneration. J Immunol 2008 1.17
57 CLEC-2 signaling via Syk in myeloid cells can regulate inflammatory responses. Eur J Immunol 2011 1.16
58 Pertussis toxin targets airway macrophages to promote Bordetella pertussis infection of the respiratory tract. Infect Immun 2007 1.15
59 Targeting tumor-associated macrophages in an orthotopic murine model of diffuse malignant mesothelioma. Mol Cancer Ther 2008 1.14
60 Neutrophils transport antigen from the dermis to the bone marrow, initiating a source of memory CD8+ T cells. Immunity 2012 1.14
61 Role of macrophages in early host resistance to respiratory Acinetobacter baumannii infection. PLoS One 2012 1.12
62 The trans-sialidase from Trypanosoma cruzi induces thrombocytopenia during acute Chagas' disease by reducing the platelet sialic acid contents. Infect Immun 2005 1.12
63 Therapeutic factor VIII levels and negligible toxicity in mouse and dog models of hemophilia A following gene therapy with high-capacity adenoviral vectors. Blood 2002 1.11
64 Contrasting roles of macrophages and dendritic cells in controlling initial pulmonary Brucella infection. Eur J Immunol 2010 1.11
65 Ulcerative colitis exacerbates lipopolysaccharide-induced damage to the nigral dopaminergic system: potential risk factor in Parkinson`s disease. J Neurochem 2010 1.11
66 Prostaglandin E₂ signaling and bacterial infection recruit tumor-promoting macrophages to mouse gastric tumors. Gastroenterology 2010 1.10
67 Cell-type-specific type I interferon antagonism influences organ tropism of murine coronavirus. J Virol 2011 1.07
68 Multiple helminth infection of the skin causes lymphocyte hypo-responsiveness mediated by Th2 conditioning of dermal myeloid cells. PLoS Pathog 2011 1.07
69 MHC class I-specific antibody binding to nonhematopoietic cells drives complement activation to induce transfusion-related acute lung injury in mice. J Exp Med 2011 1.06
70 The course of infections and pathology in immunomodulated NOD/LtSz-SCID mice inoculated with Plasmodium falciparum laboratory lines and clinical isolates. Int J Parasitol 2005 1.05
71 Distinct immune effector pathways contribute to the full expression of peanut-induced anaphylactic reactions in mice. J Allergy Clin Immunol 2011 1.05
72 The high-affinity human IgG receptor FcγRI (CD64) promotes IgG-mediated inflammation, anaphylaxis, and antitumor immunotherapy. Blood 2013 1.03
73 Cutting Edge: The murine high-affinity IgG receptor FcγRIV is sufficient for autoantibody-induced arthritis. J Immunol 2011 1.03
74 Technical advance: autofluorescence as a tool for myeloid cell analysis. J Leukoc Biol 2010 1.02
75 c-FLIP maintains tissue homeostasis by preventing apoptosis and programmed necrosis. Sci Signal 2012 1.01
76 Role of host cell traversal by the malaria sporozoite during liver infection. J Exp Med 2013 1.01
77 Iron- and inflammation-induced hepcidin gene expression in mice is not mediated by Kupffer cells in vivo. Hepatology 2005 1.01
78 Enhanced erythropoiesis in Hfe-KO mice indicates a role for Hfe in the modulation of erythroid iron homeostasis. Blood 2010 0.99
79 Contribution of TIR domain-containing adapter inducing IFN-beta-mediated IL-18 release to LPS-induced liver injury in mice. J Hepatol 2009 0.99
80 Role of Rho GTPase in astrocyte morphology and migratory response during in vitro wound healing. J Neurochem 2005 0.98
81 NK cells, but not NKT cells, are involved in Pseudomonas aeruginosa exotoxin A-induced hepatotoxicity in mice. J Immunol 2004 0.98
82 Interferon-gamma-mediated tissue factor expression contributes to T-cell-mediated hepatitis through induction of hypercoagulation in mice. Hepatology 2013 0.96
83 Fate of endothelialized modular constructs implanted in an omental pouch in nude rats. Tissue Eng Part A 2009 0.96
84 Activator protein-1 activation in acute lung injury. Am J Pathol 2002 0.95
85 Distinct macrophage subpopulations regulate viral encephalitis but not viral clearance in the CNS. J Neuroimmunol 2010 0.94
86 Silica particles enhance peripheral thrombosis: key role of lung macrophage-neutrophil cross-talk. Am J Respir Crit Care Med 2005 0.93
87 Chemokine receptor CCR2 is not essential for the development of experimental cerebral malaria. Infect Immun 2003 0.93
88 Cancer-induced expansion and activation of CD11b+ Gr-1+ cells predispose mice to adenoviral-triggered anaphylactoid-type reactions. Mol Ther 2009 0.93
89 CTLA4Ig inhibits effector T cells through regulatory T cells and TGF-β. J Immunol 2013 0.92
90 Mouse adenovirus type 1 infection of macrophages. Virology 2009 0.90
91 Systemic macrophage depletion inhibits Helicobacter bilis-induced proinflammatory cytokine-mediated typhlocolitis and impairs bacterial colonization dynamics in a BALB/c Rag2-/- mouse model of inflammatory bowel disease. Infect Immun 2012 0.89
92 Induction of gp120-specific protective immune responses by genetic vaccination with linear polyethylenimine-plasmid complex. Vaccine 2005 0.88
93 Macrophage-dependent regulation of neutrophil mobilization and chemotaxis during development of sterile peritonitis in the rat. Eur J Haematol 2002 0.88
94 Analysis of innate defences against Plasmodium falciparum in immunodeficient mice. Malar J 2010 0.87
95 The maintenance of lymphatic vessels in the cornea is dependent on the presence of macrophages. Invest Ophthalmol Vis Sci 2012 0.86
96 T-zone localized monocyte-derived dendritic cells promote Th1 priming to Salmonella. Eur J Immunol 2011 0.86
97 Conjunctival macrophage-mediated influence of the local and systemic immune response after corneal herpes simplex virus-1 infection. Immunology 2002 0.85
98 Macrophage depletion improves survival of porcine neonatal pancreatic cell clusters contained in alginate macrocapsules transplanted into rats. Xenotransplantation 2003 0.85
99 Characterization of hemodynamic events following intravascular infusion of recombinant adenovirus reveals possible solutions for mitigating cardiovascular responses. Mol Ther 2005 0.85
100 Perivascular macrophages mediate the neurovascular and cognitive dysfunction associated with hypertension. J Clin Invest 2016 0.85
101 Collaboration between macrophages and vaccine-induced CD4+ T cells confers protection against lethal Pseudomonas aeruginosa pneumonia during neutropenia. J Infect Dis 2012 0.85
102 Enhanced T-cell-independent antitumor effect of cyclophosphamide combined with anti-CD40 mAb and CpG in mice. J Immunother 2011 0.84
103 Tumor-associated myeloid cells can be activated in vitro and in vivo to mediate antitumor effects. Cancer Immunol Immunother 2012 0.83
104 Effects of macrophage depletion on peritoneal inflammation in swiss mice, edible frogs and goldfish. Folia Biol (Krakow) 2004 0.82
105 Mechanisms of macrophage cytotoxicity in IL-2 and IL-12 mediated tumour regression. Cancer Immunol Immunother 2003 0.82
106 Induction of CD8+ T lymphocytes by Salmonella typhimurium is independent of Salmonella pathogenicity island 1-mediated host cell death. J Immunol 2002 0.82
107 Innate imprinting of murine resident alveolar macrophages by allergic bronchial inflammation causes a switch from hypoinflammatory to hyperinflammatory reactivity. Am J Pathol 2012 0.81
108 Human CD47 expression permits survival of porcine cells in immunodeficient mice that express SIRPα capable of binding to human CD47. Cell Transplant 2011 0.81
109 Transient depletion of specific immune cell populations to improve adenovirus-mediated transgene expression in the liver. Liver Int 2014 0.80
110 Enhancement of Bordetella parapertussis infection by Bordetella pertussis in mixed infection of the respiratory tract. FEMS Immunol Med Microbiol 2011 0.79
111 SHP-1 regulation of mast cell function in allergic inflammation and anaphylaxis. PLoS One 2013 0.78
112 In vivo invasion of head and neck squamous cell carcinoma cells does not require macrophages. Am J Pathol 2011 0.77
113 Transient neutropenia increases macrophage accumulation and cell proliferation but does not improve repair following intratendinous rupture of Achilles tendon. J Orthop Res 2010 0.77
114 The B-cell superantigen Finegoldia magna protein L causes pulmonary inflammation by a mechanism dependent on MyD88 but not B cells or immunoglobulins. Inflamm Res 2012 0.75
115 Effect of plasma exchange in combination with deoxyspergualin on the survival of guinea-pig hearts in macrophage-depleted C6-deficient rats. Xenotransplantation 2003 0.75
116 Minor effect of depletion of resident macrophages from peritoneal cavity on resistance of common carp Cyprinus carpio to blood flagellates. Dis Aquat Organ 2003 0.75