Published in PLoS Pathog on February 08, 2008
Candida albicans pathogenicity mechanisms. Virulence (2013) 2.60
An iron homeostasis regulatory circuit with reciprocal roles in Candida albicans commensalism and pathogenesis. Cell Host Microbe (2011) 2.23
Candida albicans Hyr1p confers resistance to neutrophil killing and is a potential vaccine target. J Infect Dis (2010) 1.96
Role of the gut microbiota in defining human health. Expert Rev Anti Infect Ther (2010) 1.73
Essential role for neutrophils but not alveolar macrophages at early time points following Aspergillus fumigatus infection. J Infect Dis (2009) 1.68
Chemokine receptor Ccr1 drives neutrophil-mediated kidney immunopathology and mortality in invasive candidiasis. PLoS Pathog (2012) 1.49
A multifunctional, synthetic Gaussia princeps luciferase reporter for live imaging of Candida albicans infections. Infect Immun (2009) 1.48
Candida albicans and bacterial microbiota interactions in the cecum during recolonization following broad-spectrum antibiotic therapy. Infect Immun (2012) 1.36
Candida albicans hyphal formation and virulence assessed using a Caenorhabditis elegans infection model. Eukaryot Cell (2009) 1.33
Candida albicans-endothelial cell interactions: a key step in the pathogenesis of systemic candidiasis. Infect Immun (2008) 1.26
Candida albicans infection of Caenorhabditis elegans induces antifungal immune defenses. PLoS Pathog (2011) 1.24
Recent insights into Candida albicans biofilm resistance mechanisms. Curr Genet (2013) 1.20
Synergistic interaction between Candida albicans and commensal oral streptococci in a novel in vitro mucosal model. Infect Immun (2011) 1.20
Candida albicans commensalism and pathogenicity are intertwined traits directed by a tightly knit transcriptional regulatory circuit. PLoS Biol (2013) 1.18
Hosting infection: experimental models to assay Candida virulence. Int J Microbiol (2011) 1.14
Role of neutrophils in IL-17-dependent immunity to mucosal candidiasis. J Immunol (2014) 1.13
Echinocandin resistance, susceptibility testing and prophylaxis: implications for patient management. Drugs (2014) 1.10
Normal adaptation of Candida albicans to the murine gastrointestinal tract requires Efg1p-dependent regulation of metabolic and host defense genes. Eukaryot Cell (2012) 1.06
Variation in Candida albicans EFG1 expression enables host-dependent changes in colonizing fungal populations. MBio (2012) 1.06
New insights into innate immune control of systemic candidiasis. Med Mycol (2014) 1.05
The tetraspanin protein CD37 regulates IgA responses and anti-fungal immunity. PLoS Pathog (2009) 1.05
Thriving within the host: Candida spp. interactions with phagocytic cells. Med Microbiol Immunol (2013) 1.02
Recent progress in vaccines against fungal diseases. Curr Opin Microbiol (2012) 1.00
Activation of HIF-1α and LL-37 by commensal bacteria inhibits Candida albicans colonization. Nat Med (2015) 0.99
Oxidative stress responses in the human fungal pathogen, Candida albicans. Biomolecules (2015) 0.99
Role of neutrophils, MyD88-mediated neutrophil recruitment, and complement in antibody-mediated defense against Pseudomonas aeruginosa keratitis. Invest Ophthalmol Vis Sci (2009) 0.98
Murine models of Candida gastrointestinal colonization and dissemination. Eukaryot Cell (2013) 0.97
Forward genetics in Candida albicans that reveals the Arp2/3 complex is required for hyphal formation, but not endocytosis. Mol Microbiol (2010) 0.97
Autophagy enhances NFκB activity in specific tissue macrophages by sequestering A20 to boost antifungal immunity. Nat Commun (2015) 0.97
Serological profiling of a Candida albicans protein microarray reveals permanent host-pathogen interplay and stage-specific responses during candidemia. PLoS Pathog (2010) 0.96
Pathogen and host factors are needed to provoke a systemic host response to gastrointestinal infection of Drosophila larvae by Candida albicans. Dis Model Mech (2011) 0.95
Innocent until proven guilty: mechanisms and roles of Streptococcus-Candida interactions in oral health and disease. Mol Oral Microbiol (2014) 0.95
Dectin-1 is not required for controlling Candida albicans colonization of the gastrointestinal tract. Infect Immun (2012) 0.93
Echinocandin Resistance in Candida. Clin Infect Dis (2015) 0.93
Vaccines for invasive fungal infections. F1000 Med Rep (2011) 0.92
A virtual infection model quantifies innate effector mechanisms and Candida albicans immune escape in human blood. PLoS Comput Biol (2014) 0.91
The role of Candida albicans AP-1 protein against host derived ROS in in vivo models of infection. Virulence (2013) 0.90
Neutrophils mediate immunopathology and negatively regulate protective immune responses during fatal bacterial infection-induced toxic shock. Infect Immun (2013) 0.90
Impact of antifungal prophylaxis on colonization and azole susceptibility of Candida species. Antimicrob Agents Chemother (2009) 0.88
Multicenter outbreak of infections by Saprochaete clavata, an unrecognized opportunistic fungal pathogen. MBio (2014) 0.88
Horizontal transmission of Candida albicans and evidence of a vaccine response in mice colonized with the fungus. PLoS One (2011) 0.88
Essential role for vacuolar acidification in Candida albicans virulence. J Biol Chem (2013) 0.88
Macrophage killing of bacterial and fungal pathogens is not inhibited by intense intracellular accumulation of the lipoglycopeptide antibiotic oritavancin. Clin Infect Dis (2012) 0.88
Candida albicans Inhibits Pseudomonas aeruginosa Virulence through Suppression of Pyochelin and Pyoverdine Biosynthesis. PLoS Pathog (2015) 0.88
Expansion of Foxp3(+) T-cell populations by Candida albicans enhances both Th17-cell responses and fungal dissemination after intravenous challenge. Eur J Immunol (2014) 0.87
Novel insights into disseminated candidiasis: pathogenesis research and clinical experience converge. PLoS Pathog (2008) 0.86
Niche-specific requirement for hyphal wall protein 1 in virulence of Candida albicans. PLoS One (2013) 0.86
Candida albicans colonization and dissemination from the murine gastrointestinal tract: the influence of morphology and Th17 immunity. Cell Microbiol (2014) 0.86
MyD88-dependent signaling protects against anthrax lethal toxin-induced impairment of intestinal barrier function. Infect Immun (2010) 0.84
CX3CR1 is dispensable for control of mucosal Candida albicans infections in mice and humans. Infect Immun (2014) 0.82
Host response to Candida albicans bloodstream infection and sepsis. Virulence (2015) 0.82
A comparative histopathological study of systemic candidiasis in association with experimentally induced breast cancer. Oncol Lett (2010) 0.79
Immunosensing during colonization by Candida albicans: does it take a village to colonize the intestine? Trends Microbiol (2011) 0.79
Distinct stages during colonization of the mouse gastrointestinal tract by Candida albicans. Front Microbiol (2015) 0.78
Using Bayesian modelling to investigate factors governing antibiotic-induced Candida albicans colonization of the GI tract. Sci Rep (2015) 0.78
MIG1 Regulates Resistance of Candida albicans against the Fungistatic Effect of Weak Organic Acids. Eukaryot Cell (2015) 0.78
Overview of vertebrate animal models of fungal infection. J Immunol Methods (2014) 0.77
Function and Regulation of Cph2 in Candida albicans. Eukaryot Cell (2015) 0.77
How Chemotherapy Increases the Risk of Systemic Candidiasis in Cancer Patients: Current Paradigm and Future Directions. Pathogens (2016) 0.77
Ageing exacerbates damage of systemic and salivary neutrophils from patients presenting Candida-related denture stomatitis. Immun Ageing (2009) 0.77
Host defense mechanisms in invasive candidiasis originating in the GI tract. Expert Rev Anti Infect Ther (2008) 0.76
A mouse model for Candida glabrata hematogenous disseminated infection starting from the gut: evaluation of strains with different adhesion properties. PLoS One (2013) 0.76
Plasticity of neutrophils reveals modulatory capacity. Braz J Med Biol Res (2015) 0.76
Systems Level Dissection of Candida Recognition by Dectins: A Matter of Fungal Morphology and Site of Infection. Pathogens (2015) 0.76
Candida albicans Pathogenesis: Fitting within the Host-Microbe Damage Response Framework. Infect Immun (2016) 0.76
The complexities of bacterial-fungal interactions in the mammalian gastrointestinal tract. Microb Cell (2016) 0.75
Effect of Antifungal Treatment in a Diet-based Murine Model of Disseminated Candidiasis Acquired via the Gastrointestinal Tract. Antimicrob Agents Chemother (2016) 0.75
Cell Intrinsic Galectin-3 Attenuates Neutrophil ROS-Dependent Killing of Candida by Modulating CR3 Downstream Syk Activation. Front Immunol (2017) 0.75
Polymicrobial Biofilm Studies: From Basic Science to Biofilm Control. Curr Oral Health Rep (2016) 0.75
Beyond Candida albicans: Mechanisms of immunity to non-albicans Candida species. Cytokine (2015) 0.75
Intra-amniotic Candida albicans infection induces mucosal injury and inflammation in the ovine fetal intestine. Sci Rep (2016) 0.75
Analysis of Immune Response Markers in Jorge Lobo's Disease Lesions Suggests the Occurrence of Mixed T Helper Responses with the Dominance of Regulatory T Cell Activity. PLoS One (2015) 0.75
Commensal enteric bacteria lipopolysaccharide impairs host defense against disseminated Candida albicans fungal infection. Mucosal Immunol (2014) 0.75
Antifungal Immunological Defenses in Newborns. Front Immunol (2017) 0.75
New insights on the development of fungal vaccines: from immunity to recent challenges. Mem Inst Oswaldo Cruz (2015) 0.75
β-glucan Exposure on the Fungal Cell Wall Tightly Correlates with Competitive Fitness of Candida Species in the Mouse Gastrointestinal Tract. Front Cell Infect Microbiol (2016) 0.75
Binding of Candida albicans to Human CEACAM1 and CEACAM6 Modulates the Inflammatory Response of Intestinal Epithelial Cells. MBio (2017) 0.75
Lactic acid bacteria differentially regulate filamentation in two heritable cell types of the human fungal pathogen Candida albicans. Mol Microbiol (2016) 0.75
Identifying host immune effectors critical for protection against Candida albicans infections. Virulence (2016) 0.75
Intestinal colonization by Candida albicans alters inflammatory responses in Bruton's tyrosine kinase-deficient mice. PLoS One (2014) 0.75
Host pathogen relations: exploring animal models for fungal pathogens. Pathogens (2014) 0.75
Blunted dynamics of adenosine A2A receptors is associated with increased susceptibility to Candida albicans infection in the elderly. Oncotarget (2016) 0.75
Active immunizations with peptide-DC vaccines and passive transfer with antibodies protect neutropenic mice against disseminated candidiasis. Vaccine (2015) 0.75
The game theory of Candida albicans colonization dynamics reveals host status-responsive gene expression. BMC Syst Biol (2016) 0.75
Epidemiology and phospholipase activity of oral Candida SPP. Among patients with central nervous system diseases before and after dental cleaning procedure. Braz J Microbiol (2010) 0.75
The microbiome in hematopoietic stem cell transplant recipients and cancer patients: Opportunities for clinical advances that reduce infection. PLoS Pathog (2017) 0.75
The Candida albicans HIR histone chaperone regulates the yeast-to-hyphae transition by controlling the sensitivity to morphogenesis signals. Sci Rep (2017) 0.75
Comparison Between Carbapenems and β-Lactam/β-Lactamase Inhibitors in the Treatment for Bloodstream Infections Caused by Extended-Spectrum β-Lactamase-Producing Enterobacteriaceae: A Systematic Review and Meta-Analysis. Open Forum Infect Dis (2017) 0.75
Isogenic strain construction and gene mapping in Candida albicans. Genetics (1993) 17.18
Nonfilamentous C. albicans mutants are avirulent. Cell (1997) 13.83
Liposome mediated depletion of macrophages: mechanism of action, preparation of liposomes and applications. J Immunol Methods (1994) 13.53
A novel method in the induction of reliable experimental acute and chronic ulcerative colitis in mice. Gastroenterology (1990) 11.22
Clinicopathologic study of dextran sulfate sodium experimental murine colitis. Lab Invest (1993) 10.09
Attributable mortality of nosocomial candidemia, revisited. Clin Infect Dis (2003) 7.09
Control of filament formation in Candida albicans by the transcriptional repressor TUP1. Science (1997) 6.60
Trends in the postmortem epidemiology of invasive fungal infections at a university hospital. J Infect (1996) 4.26
Fungal infections in cancer patients: an international autopsy survey. Eur J Clin Microbiol Infect Dis (1992) 3.16
Linkage of adhesion, filamentous growth, and virulence in Candida albicans to a single gene, INT1. Science (1998) 3.04
Candida albicans Als1p: an adhesin that is a downstream effector of the EFG1 filamentation pathway. Mol Microbiol (2002) 3.01
Signaling through adenylyl cyclase is essential for hyphal growth and virulence in the pathogenic fungus Candida albicans. Mol Biol Cell (2001) 2.99
Differential susceptibility of inbred mouse strains to dextran sulfate sodium-induced colitis. Am J Physiol (1998) 2.76
The direct cost and incidence of systemic fungal infections. Value Health (2002) 2.64
In vivo pharmacokinetics and pharmacodynamics of a new triazole, voriconazole, in a murine candidiasis model. Antimicrob Agents Chemother (2003) 2.60
Elimination of mouse splenic macrophages correlates with increased susceptibility to experimental disseminated candidiasis. J Immunol (1994) 2.34
The immune response to fungal infections. Br J Haematol (2005) 2.24
Evidence for macrophage-mediated protection against lethal Candida albicans infection. Infect Immun (1986) 1.86
Revisiting the source of candidemia: skin or gut? Clin Infect Dis (2001) 1.77
Bacterial translocation from the gastrointestinal tract. Adv Exp Med Biol (1999) 1.60
Mechanisms of host defense against Candida species. I. Phagocytosis by monocytes and monocyte-derived macrophages. J Immunol (1991) 1.58
Role of L3T4+ lymphocytes in protective immunity to systemic Candida albicans infection in mice. Infect Immun (1989) 1.56
Risk factors for candidemia in patients with acute lymphocytic leukemia. Rev Infect Dis (1991) 1.51
Human malaria in immunocompromised mice: an in vivo model to study defense mechanisms against Plasmodium falciparum. J Exp Med (2000) 1.50
Role of anaerobic flora in the translocation of aerobic and facultatively anaerobic intestinal bacteria. Infect Immun (1987) 1.46
Passive protection against Pseudomonas aeruginosa infection in an experimental leukopenic mouse model. Infect Immun (1983) 1.45
Administration of antigranulocyte monoclonal antibody RB6-8C5 prevents expression of acquired resistance to Listeria monocytogenes infection in previously immunized mice. Infect Immun (1994) 1.45
Virulence of Pseudomonas aeruginosa in a murine model of gastrointestinal colonization and dissemination in neutropenia. Infect Immun (2005) 1.34
Role of calcineurin in stress resistance, morphogenesis, and virulence of a Candida albicans wild-type strain. Infect Immun (2006) 1.32
Neutrophil depletion increases susceptibility to systemic and vaginal candidiasis in mice, and reveals differences between brain and kidney in mechanisms of host resistance. Microbiology (1996) 1.28
Gastrointestinal colonization and systemic dissemination by Candida albicans and Candida tropicalis in intact and immunocompromised mice. Infect Immun (1992) 1.21
The pathogenesis of acute systemic candidiasis in a susceptible inbred mouse strain. J Pathol (1986) 1.18
Candida albicans killing by RAW 264.7 mouse macrophage cells: effects of Candida genotype, infection ratios, and gamma interferon treatment. Infect Immun (2002) 1.18
Salmonella enterica serovar typhi modulates cell surface expression of its receptor, the cystic fibrosis transmembrane conductance regulator, on the intestinal epithelium. Infect Immun (2002) 1.14
A model of sustained gastrointestinal colonization by Candida albicans in healthy adult mice. Infect Immun (1990) 1.12
Invasive fungal infections in pediatric oncology patients: 11-year experience at a single institution. J Pediatr Hematol Oncol (2005) 1.11
The role of activated macrophages in resistance to experimental renal candidiasis. J Reticuloendothel Soc (1977) 1.07
In vivo immune responses to Candida albicans modified by treatment with recombinant murine gamma interferon. Infect Immun (1989) 1.07
Sustained gastrointestinal colonization and systemic dissemination by Candida albicans, Candida tropicalis and Candida parapsilosis in adult mice. Diagn Microbiol Infect Dis (2000) 1.06
Gastrointestinal and systemic candidosis in immunocompromised mice. J Med Vet Mycol (1989) 1.05
Comparative virulence of Candida albicans yeast and filamentous forms in orally and intravenously inoculated mice. Crit Care Med (2003) 1.05
Effect of mouse phagocytes on Candida albicans in in vivo chambers. Infect Immun (1981) 1.05
Role of complement C5 and T lymphocytes in pathogenesis of disseminated and mucosal candidiasis in susceptible DBA/2 mice. Microb Pathog (2003) 1.05
Macrophage-dependent candidacidal mechanisms in the murine system. Comparison of murine Kupffer cell and peritoneal macrophage candidacidal mechanisms. J Immunol (1993) 1.04
Invasive candidiasis in cancer patients: observations from a randomized clinical trial. J Infect (2005) 1.02
Role of activated macrophages in resistance to systemic candidosis. J Leukoc Biol (1988) 1.01
Experimental pulmonary candidiasis. Mycopathologia (1990) 0.98
Candida tropicalis infections in children with leukemia. Leuk Lymphoma (1993) 0.96
Gastrointestinal colonization by Candida albicans mutant strains in antibiotic-treated mice. Clin Diagn Lab Immunol (2001) 0.96
Analysis of the serologic response to systemic Candida albicans infection in a murine model. Proteomics (2001) 0.95
Systemic candidosis in silica-treated athymic and euthymic mice. Infect Immun (1983) 0.94
Candida glabrata and Candida albicans; dissimilar tissue tropism and infectivity in a gnotobiotic model of mucosal candidiasis. FEMS Immunol Med Microbiol (2007) 0.94
Corneal virulence of Candida albicans strains deficient in Tup1-regulated genes. Invest Ophthalmol Vis Sci (2007) 0.93
Development of an orogastrointestinal mucosal model of candidiasis with dissemination to visceral organs. Antimicrob Agents Chemother (2006) 0.93
Hypoxia and extraintestinal dissemination of Candida albicans yeast forms. Shock (2003) 0.92
A prospective study of septicaemia on a paediatric oncology unit: a three-year experience at The Royal Liverpool Children's Hospital, Alder Hey, UK. Eur J Cancer (2005) 0.91
CD8+ T cells but not polymorphonuclear leukocytes are required to limit chronic oral carriage of Candida albicans in transgenic mice expressing human immunodeficiency virus type 1. Infect Immun (2006) 0.91
Risk factors and outcome for nosocomial breakthrough candidaemia. J Infect (2005) 0.90
Host-parasite interactions in the pathogenesis of experimental renal candidiasis. Lab Invest (1983) 0.90
Translocation model of Candida albicans in DBA-2/J mice with protein calorie malnutrition mimics hematogenous candidiasis in humans. Microb Pathog (2003) 0.85
Effect of lectins on hepatic clearance and killing of Candida albicans by the isolated perfused mouse liver. Infect Immun (1992) 0.85
Invasive fungal infections in pediatric patients with leukemia: emphasis on pulmonary and dermatological manifestations. Acta Paediatr Taiwan (2005) 0.82
Lung infections associated with cystic fibrosis. Clin Microbiol Rev (2002) 9.20
Subpopulations of mouse blood monocytes differ in maturation stage and inflammatory response. J Immunol (2004) 8.65
Chitin induces accumulation in tissue of innate immune cells associated with allergy. Nature (2007) 5.82
NF-kappaB is a negative regulator of IL-1beta secretion as revealed by genetic and pharmacological inhibition of IKKbeta. Cell (2007) 4.56
Memory T(H)2 cells induce alternatively activated macrophages to mediate protection against nematode parasites. Nat Med (2006) 4.16
Control of TH17 cells occurs in the small intestine. Nature (2011) 4.03
Macrophage-derived Wnt opposes Notch signaling to specify hepatic progenitor cell fate in chronic liver disease. Nat Med (2012) 3.96
Inflammation-induced lymphangiogenesis in the cornea arises from CD11b-positive macrophages. J Clin Invest (2005) 3.77
Immunochemical properties of the staphylococcal poly-N-acetylglucosamine surface polysaccharide. Infect Immun (2002) 3.14
Ly6c+ "inflammatory monocytes" are microglial precursors recruited in a pathogenic manner in West Nile virus encephalitis. J Exp Med (2008) 3.08
Intraspecific diversity of Yersinia pestis. Clin Microbiol Rev (2004) 3.03
An essential role for TH2-type responses in limiting acute tissue damage during experimental helminth infection. Nat Med (2012) 2.60
Phagocyte-derived catecholamines enhance acute inflammatory injury. Nature (2007) 2.56
Protective influenza-specific CD8 T cell responses require interactions with dendritic cells in the lungs. J Exp Med (2008) 2.55
Alum induces innate immune responses through macrophage and mast cell sensors, but these sensors are not required for alum to act as an adjuvant for specific immunity. J Immunol (2009) 2.47
Monocyte chemoattractant protein-1 regulation of blood-brain barrier permeability. J Cereb Blood Flow Metab (2005) 2.45
Comparative opsonic and protective activities of Staphylococcus aureus conjugate vaccines containing native or deacetylated Staphylococcal Poly-N-acetyl-beta-(1-6)-glucosamine. Infect Immun (2005) 2.37
Harnessing Hsp90 function as a powerful, broadly effective therapeutic strategy for fungal infectious disease. Proc Natl Acad Sci U S A (2009) 2.35
Macrophages prevent human red blood cell reconstitution in immunodeficient mice. Blood (2011) 2.24
Mouse and human neutrophils induce anaphylaxis. J Clin Invest (2011) 2.21
Dispersion as an important step in the Candida albicans biofilm developmental cycle. PLoS Pathog (2010) 2.09
The Ly-6Chigh monocyte subpopulation transports Listeria monocytogenes into the brain during systemic infection of mice. J Immunol (2004) 2.07
The pgaABCD locus of Acinetobacter baumannii encodes the production of poly-beta-1-6-N-acetylglucosamine, which is critical for biofilm formation. J Bacteriol (2009) 2.06
Macrophages and skeletal muscle regeneration: a clodronate-containing liposome depletion study. Am J Physiol Regul Integr Comp Physiol (2006) 1.94
Roles of macrophages and neutrophils in the early host response to Bacillus anthracis spores in a mouse model of infection. Infect Immun (2006) 1.93
Use of confocal microscopy to analyze the rate of vancomycin penetration through Staphylococcus aureus biofilms. Antimicrob Agents Chemother (2005) 1.91
Macrophages support pathological erythropoiesis in polycythemia vera and β-thalassemia. Nat Med (2013) 1.89
Lung interstitial macrophages alter dendritic cell functions to prevent airway allergy in mice. J Clin Invest (2009) 1.87
High levels of antibody to panton-valentine leukocidin are not associated with resistance to Staphylococcus aureus-associated skin and soft-tissue infection. Clin Infect Dis (2010) 1.84
Deficient natural killer cell cytotoxicity in patients with IKK-gamma/NEMO mutations. J Clin Invest (2002) 1.83
The teicoplanin-associated locus regulator (TcaR) and the intercellular adhesin locus regulator (IcaR) are transcriptional inhibitors of the ica locus in Staphylococcus aureus. J Bacteriol (2004) 1.81
Poly-N-acetylglucosamine production in Staphylococcus aureus is essential for virulence in murine models of systemic infection. Infect Immun (2005) 1.80
Universal vaccine based on ectodomain of matrix protein 2 of influenza A: Fc receptors and alveolar macrophages mediate protection. J Immunol (2010) 1.79
Respiratory syncytial virus-induced activation of nuclear factor-kappaB in the lung involves alveolar macrophages and toll-like receptor 4-dependent pathways. J Infect Dis (2002) 1.77
Adenovirus vector-induced innate inflammatory mediators, MAPK signaling, as well as adaptive immune responses are dependent upon both TLR2 and TLR9 in vivo. J Immunol (2008) 1.76
Osteal macrophages promote in vivo intramembranous bone healing in a mouse tibial injury model. J Bone Miner Res (2011) 1.76
Cystic fibrosis transmembrane conductance regulator and caveolin-1 regulate epithelial cell internalization of Pseudomonas aeruginosa. Am J Physiol Cell Physiol (2009) 1.72
Methicillin resistance alters the biofilm phenotype and attenuates virulence in Staphylococcus aureus device-associated infections. PLoS Pathog (2012) 1.72
Immune-activating properties of Panton-Valentine leukocidin improve the outcome in a model of methicillin-resistant Staphylococcus aureus pneumonia. Infect Immun (2012) 1.70
WNT signaling drives cholangiocarcinoma growth and can be pharmacologically inhibited. J Clin Invest (2015) 1.68
Nonmucoid Pseudomonas aeruginosa expresses alginate in the lungs of patients with cystic fibrosis and in a mouse model. J Infect Dis (2005) 1.62
Identification of a 5-nucleotide sequence that controls expression of the ica locus in Staphylococcus aureus and characterization of the DNA-binding properties of IcaR. Mol Microbiol (2003) 1.61
In vitro-derived alternatively activated macrophages reduce colonic inflammation in mice. Gastroenterology (2010) 1.61
Activated macrophages are essential in a murine model for T cell-mediated chronic psoriasiform skin inflammation. J Clin Invest (2006) 1.58
Lack of CD47 on nonhematopoietic cells induces split macrophage tolerance to CD47null cells. Proc Natl Acad Sci U S A (2007) 1.58
C5a initiates the inflammatory cascade in immune complex peritonitis. J Immunol (2004) 1.57
Role of T cells in innate and adaptive immunity against murine Burkholderia pseudomallei infection. J Infect Dis (2005) 1.56
The EGF/CSF-1 paracrine invasion loop can be triggered by heregulin beta1 and CXCL12. Cancer Res (2009) 1.56
Localization of cystic fibrosis transmembrane conductance regulator to lipid rafts of epithelial cells is required for Pseudomonas aeruginosa-induced cellular activation. J Immunol (2004) 1.56
Characterization of the opsonic and protective activity against Staphylococcus aureus of fully human monoclonal antibodies specific for the bacterial surface polysaccharide poly-N-acetylglucosamine. Infect Immun (2006) 1.52
Inescapable need for neutrophils as mediators of cellular innate immunity to acute Pseudomonas aeruginosa pneumonia. Infect Immun (2009) 1.52
IL-15 trans-presentation by pulmonary dendritic cells promotes effector CD8 T cell survival during influenza virus infection. J Exp Med (2010) 1.52
ClpXP proteases positively regulate alginate overexpression and mucoid conversion in Pseudomonas aeruginosa. Microbiology (2008) 1.52
CaNAT1, a heterologous dominant selectable marker for transformation of Candida albicans and other pathogenic Candida species. Infect Immun (2005) 1.51
Macrophages mediate inflammation-enhanced metastasis of ovarian tumors in mice. Cancer Res (2007) 1.50
Cochlin produced by follicular dendritic cells promotes antibacterial innate immunity. Immunity (2013) 1.50
Antibody-mediated enhancement of community-acquired methicillin-resistant Staphylococcus aureus infection. Proc Natl Acad Sci U S A (2010) 1.49
Type I IFNs enhance susceptibility to Chlamydia muridarum lung infection by enhancing apoptosis of local macrophages. J Immunol (2008) 1.49
Naïve CD8 T cell activation by liver bone marrow-derived cells leads to a "neglected" IL-2low Bimhigh phenotype, poor CTL function and cell death. J Hepatol (2012) 1.48
Isolation, structural characterization, and immunological evaluation of a high-molecular-weight exopolysaccharide from Staphylococcus aureus. Carbohydr Res (2003) 1.44
CFTR is a pattern recognition molecule that extracts Pseudomonas aeruginosa LPS from the outer membrane into epithelial cells and activates NF-kappa B translocation. Proc Natl Acad Sci U S A (2002) 1.44
Mannose receptor expression specifically reveals perivascular macrophages in normal, injured, and diseased mouse brain. Glia (2005) 1.42
IL-17 is a critical component of vaccine-induced protection against lung infection by lipopolysaccharide-heterologous strains of Pseudomonas aeruginosa. J Immunol (2008) 1.42
Transcription of quorum-sensing system genes in clinical and environmental isolates of Pseudomonas aeruginosa. J Bacteriol (2003) 1.40
Hypersusceptibility of cystic fibrosis mice to chronic Pseudomonas aeruginosa oropharyngeal colonization and lung infection. Proc Natl Acad Sci U S A (2003) 1.40
Influenza virus-like particles containing M2 induce broadly cross protective immunity. PLoS One (2011) 1.40
Quantitative analysis of adhesion and biofilm formation on hydrophilic and hydrophobic surfaces of clinical isolates of Staphylococcus epidermidis. Res Microbiol (2005) 1.38
ICAM-1 triggers liver regeneration through leukocyte recruitment and Kupffer cell-dependent release of TNF-alpha/IL-6 in mice. Gastroenterology (2003) 1.37
Molecular basis for preferential protective efficacy of antibodies directed to the poorly acetylated form of staphylococcal poly-N-acetyl-beta-(1-6)-glucosamine. Infect Immun (2007) 1.35
Virulence of Pseudomonas aeruginosa in a murine model of gastrointestinal colonization and dissemination in neutropenia. Infect Immun (2005) 1.34
A comprehensive analysis of in vitro and in vivo genetic fitness of Pseudomonas aeruginosa using high-throughput sequencing of transposon libraries. PLoS Pathog (2013) 1.34
Protection against Escherichia coli infection by antibody to the Staphylococcus aureus poly-N-acetylglucosamine surface polysaccharide. Proc Natl Acad Sci U S A (2007) 1.34
Comparative assessment of antibiotic susceptibility of coagulase-negative staphylococci in biofilm versus planktonic culture as assessed by bacterial enumeration or rapid XTT colorimetry. J Antimicrob Chemother (2005) 1.33
Extratumoral macrophages promote tumor and vascular growth in an orthotopic rat prostate tumor model. Neoplasia (2009) 1.33
Tissue macrophages suppress viral replication and prevent severe immunopathology in an interferon-I-dependent manner in mice. Hepatology (2010) 1.33
Vaccines and immunotherapy against Pseudomonas aeruginosa. Vaccine (2007) 1.31
Host resistance to lung infection mediated by major vault protein in epithelial cells. Science (2007) 1.30
Neutrophil depletion causes a fatal defect in murine pulmonary Staphylococcus aureus clearance. J Surg Res (2008) 1.30
Resistance to Pseudomonas aeruginosa chronic lung infection requires cystic fibrosis transmembrane conductance regulator-modulated interleukin-1 (IL-1) release and signaling through the IL-1 receptor. Infect Immun (2007) 1.30
Pseudomonas aeruginosa-induced apoptosis is defective in respiratory epithelial cells expressing mutant cystic fibrosis transmembrane conductance regulator. Am J Respir Cell Mol Biol (2003) 1.30
Glycolipid presentation to natural killer T cells differs in an organ-dependent fashion. Proc Natl Acad Sci U S A (2005) 1.29
Biologic properties and vaccine potential of the staphylococcal poly-N-acetyl glucosamine surface polysaccharide. Vaccine (2004) 1.29
Synthetic {beta}-(1->6)-linked N-acetylated and nonacetylated oligoglucosamines used to produce conjugate vaccines for bacterial pathogens. Infect Immun (2009) 1.29
The mechanism of anti-CD20-mediated B cell depletion revealed by intravital imaging. J Clin Invest (2013) 1.27
Evasion by stealth: inefficient immune activation underlies poor T cell response and severe disease in SARS-CoV-infected mice. PLoS Pathog (2009) 1.24
Antiglioma immunological memory in response to conditional cytotoxic/immune-stimulatory gene therapy: humoral and cellular immunity lead to tumor regression. Clin Cancer Res (2009) 1.24
Antibody to a conserved antigenic target is protective against diverse prokaryotic and eukaryotic pathogens. Proc Natl Acad Sci U S A (2013) 1.23
Vaccination inducing broad and improved cross protection against multiple subtypes of influenza A virus. Proc Natl Acad Sci U S A (2010) 1.22
Early activation of the alveolar macrophage is critical to the development of lung ischemia-reperfusion injury. J Thorac Cardiovasc Surg (2003) 1.22
A hemodynamic response to intravenous adenovirus vector particles is caused by systemic Kupffer cell-mediated activation of endothelial cells. Hum Gene Ther (2003) 1.22
Temperature-dependent variations and intraspecies diversity of the structure of the lipopolysaccharide of Yersinia pestis. Biochemistry (2005) 1.21
Liver-stage development of Plasmodium falciparum, in a humanized mouse model. J Infect Dis (2006) 1.21
Airway epithelial control of Pseudomonas aeruginosa infection in cystic fibrosis. Trends Mol Med (2008) 1.21
Modulation of macrophage activation state protects tissue from necrosis during critical limb ischemia in thrombospondin-1-deficient mice. PLoS One (2008) 1.21
Stat3 activation in acute lung injury. J Immunol (2004) 1.18
The galU Gene of Pseudomonas aeruginosa is required for corneal infection and efficient systemic spread following pneumonia but not for infection confined to the lung. Infect Immun (2004) 1.18
Conserved and variable structural features in the lipopolysaccharide of Pseudomonas aeruginosa. J Endotoxin Res (2006) 1.17