Published in Development on March 05, 2008
Endoreplication: polyploidy with purpose. Genes Dev (2009) 2.78
Persistent telomere damage induces bypass of mitosis and tetraploidy. Cell (2010) 2.45
Differentiation of trophoblast stem cells into giant cells is triggered by p57/Kip2 inhibition of CDK1 activity. Genes Dev (2008) 2.27
Control of Drosophila endocycles by E2F and CRL4(CDT2). Nature (2011) 1.89
Atypical E2F activity restrains APC/CCCS52A2 function obligatory for endocycle onset. Proc Natl Acad Sci U S A (2008) 1.70
Endoreplication and polyploidy: insights into development and disease. Development (2013) 1.66
Endocycling cells do not apoptose in response to DNA rereplication genotoxic stress. Genes Dev (2008) 1.53
CDKB1;1 forms a functional complex with CYCA2;3 to suppress endocycle onset. Plant Physiol (2009) 1.31
The anaphase-promoting complex/cyclosome (APC/C) is required for rereplication control in endoreplication cycles. Genes Dev (2008) 1.26
GIGAS CELL1, a novel negative regulator of the anaphase-promoting complex/cyclosome, is required for proper mitotic progression and cell fate determination in Arabidopsis. Plant Cell (2011) 1.15
The origin recognition complex is dispensable for endoreplication in Drosophila. Proc Natl Acad Sci U S A (2008) 1.14
SIAMESE cooperates with the CDH1-like protein CCS52A1 to establish endoreplication in Arabidopsis thaliana trichomes. Genetics (2010) 1.12
Developmentally programmed endoreduplication in animals. Cell Cycle (2009) 1.10
Arabidopsis ULTRAVIOLET-B-INSENSITIVE4 maintains cell division activity by temporal inhibition of the anaphase-promoting complex/cyclosome. Plant Cell (2011) 1.08
Cip/Kip cyclin-dependent protein kinase inhibitors and the road to polyploidy. Cell Div (2009) 1.01
Cullin 4-ring finger-ligase plays a key role in the control of endoreplication cycles in Arabidopsis trichomes. Proc Natl Acad Sci U S A (2010) 1.00
The spindle checkpoint, APC/C(Cdc20), and APC/C(Cdh1) play distinct roles in connecting mitosis to S phase. J Cell Biol (2013) 0.97
Endoreplication. Cold Spring Harb Perspect Biol (2013) 0.97
Transcriptional repression of the APC/C activator CCS52A1 promotes active termination of cell growth. EMBO J (2012) 0.96
Rice APC/C(TE) controls tillering by mediating the degradation of MONOCULM 1. Nat Commun (2012) 0.96
Dampened activity of E2F1-DP and Myb-MuvB transcription factors in Drosophila endocycling cells. J Cell Sci (2010) 0.95
Induction of endocycles represses apoptosis independently of differentiation and predisposes cells to genome instability. Development (2013) 0.95
Elucidating the functional role of endoreduplication in tomato fruit development. Ann Bot (2011) 0.93
The Cyclin-dependent kinase inhibitor Dacapo promotes genomic stability during premeiotic S phase. Mol Biol Cell (2009) 0.88
"The Octet": Eight Protein Kinases that Control Mammalian DNA Replication. Front Physiol (2012) 0.88
FOUR LIPS and MYB88 conditionally restrict the G1/S transition during stomatal formation. J Exp Bot (2013) 0.82
Making big cells: one size does not fit all. Proc Natl Acad Sci U S A (2013) 0.79
Robustness of cell cycle control and flexible orders of signaling events. Sci Rep (2015) 0.78
Cdk5-mediated inhibition of APC/C-Cdh1 switches on the cyclin D1-Cdk4-pRb pathway causing aberrant S-phase entry of postmitotic neurons. Sci Rep (2015) 0.78
The dual roles of geminin during trophoblast proliferation and differentiation. Dev Biol (2014) 0.78
The CDK regulators Cdh1 and Sic1 promote efficient usage of DNA replication origins to prevent chromosomal instability at a chromosome arm. Nucleic Acids Res (2014) 0.77
Functional specialization of chordate CDK1 paralogs during oogenic meiosis. Cell Cycle (2015) 0.76
Regulation of Unperturbed DNA Replication by Ubiquitylation. Genes (Basel) (2015) 0.76
APC/C(CDC20) and APC/C play pivotal roles in the process of embryonic development in Artemia sinica. Sci Rep (2016) 0.75
E2fl1 is a meiosis-specific transcription factor in the protist Tetrahymena thermophila. Cell Cycle (2016) 0.75
APC/C and retinoblastoma interaction: cross-talk of retinoblastoma protein with the ubiquitin proteasome pathway. Biosci Rep (2016) 0.75
Cytokinins promote onset of endoreplication by controlling cell cycle machinery. Plant Signal Behav (2014) 0.75
Snoo and Dpp Act as Spatial and Temporal Regulators Respectively of Adult Progenitor Cells in the Drosophila Trachea. PLoS Genet (2016) 0.75
Differential Regulation of Cyclin E by Yorkie-Scalloped Signaling in Organ Development. G3 (Bethesda) (2017) 0.75
scribble mutants cooperate with oncogenic Ras or Notch to cause neoplastic overgrowth in Drosophila. EMBO J (2003) 3.60
E2F1 represses beta-catenin transcription and is antagonized by both pRB and CDK8. Nature (2008) 3.24
The DrosDel deletion collection: a Drosophila genomewide chromosomal deficiency resource. Genetics (2007) 3.08
Lgl, aPKC, and Crumbs regulate the Salvador/Warts/Hippo pathway through two distinct mechanisms. Curr Biol (2010) 2.97
Upstream regulation of the hippo size control pathway. Curr Biol (2010) 2.09
Using Drosophila melanogaster to map human cancer pathways. Nat Rev Cancer (2005) 2.03
Geminin regulates neuronal differentiation by antagonizing Brg1 activity. Genes Dev (2005) 1.99
Mutation of Drosophila Lsd1 disrupts H3-K4 methylation, resulting in tissue-specific defects during development. Curr Biol (2007) 1.83
Mapping and identification of essential gene functions on the X chromosome of Drosophila. EMBO Rep (2001) 1.83
Multiple protein phosphatases are required for mitosis in Drosophila. Curr Biol (2007) 1.68
RBF1 promotes chromatin condensation through a conserved interaction with the Condensin II protein dCAP-D3. Genes Dev (2008) 1.53
The Salvador/Warts/Hippo pathway controls regenerative tissue growth in Drosophila melanogaster. Dev Biol (2010) 1.50
Pumilio facilitates miRNA regulation of the E2F3 oncogene. Genes Dev (2012) 1.36
The fusome mediates intercellular endoplasmic reticulum connectivity in Drosophila ovarian cysts. Mol Biol Cell (2004) 1.36
Abnormalities in cell proliferation and apico-basal cell polarity are separable in Drosophila lgl mutant clones in the developing eye. Dev Biol (2007) 1.33
The cyclin-dependent kinase inhibitor Dacapo promotes replication licensing during Drosophila endocycles. EMBO J (2007) 1.30
Juxtaposition of C(2)M and the transverse filament protein C(3)G within the central region of Drosophila synaptonemal complex. Proc Natl Acad Sci U S A (2005) 1.29
A role for Cdc2- and PP2A-mediated regulation of Emi2 in the maintenance of CSF arrest. Curr Biol (2007) 1.27
The lethal giant larvae tumour suppressor mutation requires dMyc oncoprotein to promote clonal malignancy. BMC Biol (2010) 1.17
Loss of the Drosophila cell polarity regulator Scribbled promotes epithelial tissue overgrowth and cooperation with oncogenic Ras-Raf through impaired Hippo pathway signaling. BMC Dev Biol (2011) 1.15
hScrib is a functional homologue of the Drosophila tumour suppressor Scribble. Oncogene (2003) 1.15
The origin recognition complex is dispensable for endoreplication in Drosophila. Proc Natl Acad Sci U S A (2008) 1.14
The p27cip/kip ortholog dacapo maintains the Drosophila oocyte in prophase of meiosis I. Development (2003) 1.13
twin, a CCR4 homolog, regulates cyclin poly(A) tail length to permit Drosophila oogenesis. Development (2005) 1.12
Bruno inhibits the expression of mitotic cyclins during the prophase I meiotic arrest of Drosophila oocytes. Dev Cell (2006) 1.11
Developmentally programmed endoreduplication in animals. Cell Cycle (2009) 1.10
Scribble mutants promote aPKC and JNK-dependent epithelial neoplasia independently of Crumbs. BMC Biol (2009) 1.09
The Scribble-Dlg-Lgl polarity module in development and cancer: from flies to man. Essays Biochem (2012) 1.09
A novel motif governs APC-dependent degradation of Drosophila ORC1 in vivo. Genes Dev (2005) 1.07
Identification of novel Ras-cooperating oncogenes in Drosophila melanogaster: a RhoGEF/Rho-family/JNK pathway is a central driver of tumorigenesis. Genetics (2011) 1.06
missing oocyte encodes a highly conserved nuclear protein required for the maintenance of the meiotic cycle and oocyte identity in Drosophila. Development (2004) 1.03
An in vivo large-scale chemical screening platform using Drosophila for anti-cancer drug discovery. Dis Model Mech (2012) 1.01
Maternal-effect loci involved in Drosophila oogenesis and embryogenesis: P element-induced mutations on the third chromosome. Int J Dev Biol (2002) 1.00
Celiac disease association with CD8+ T cell responses: identification of a novel gliadin-derived HLA-A2-restricted epitope. J Immunol (2003) 0.98
Fluorescent BrdU labeling and nuclear flow sorting of the Drosophila ovary. Methods Mol Biol (2004) 0.98
The nucleoporin Seh1 forms a complex with Mio and serves an essential tissue-specific function in Drosophila oogenesis. Development (2011) 0.96
Hfp inhibits Drosophila myc transcription and cell growth in a TFIIH/Hay-dependent manner. Development (2010) 0.95
Degradation of origin recognition complex large subunit by the anaphase-promoting complex in Drosophila. EMBO J (2003) 0.95
Lgl/aPKC and Crb regulate the Salvador/Warts/Hippo pathway. Fly (Austin) (2010) 0.92
Lgl, the SWH pathway and tumorigenesis: It's a matter of context & competition! Cell Cycle (2010) 0.92
The Brm-HDAC3-Erm repressor complex suppresses dedifferentiation in Drosophila type II neuroblast lineages. Elife (2014) 0.90
The Cyclin-dependent kinase inhibitor Dacapo promotes genomic stability during premeiotic S phase. Mol Biol Cell (2009) 0.88
Torso-like functions independently of Torso to regulate Drosophila growth and developmental timing. Proc Natl Acad Sci U S A (2013) 0.85
In Drosophila, RhoGEF2 cooperates with activated Ras in tumorigenesis through a pathway involving Rho1-Rok-Myosin-II and JNK signalling. Dis Model Mech (2013) 0.85
Genetic link between p53 and genes required for formation of the zonula adherens junction. Cancer Sci (2004) 0.84
Transcriptional regulation of the Drosophila orc2 gene by the DREF pathway. Biochim Biophys Acta (2005) 0.84
When cell cycle meets development. Development (2011) 0.83
Major signaling pathways in intestinal stem cells. Biochim Biophys Acta (2012) 0.83
The BTB-zinc finger transcription factor abrupt acts as an epithelial oncogene in Drosophila melanogaster through maintaining a progenitor-like cell state. PLoS Genet (2013) 0.83
Spotted-dick, a zinc-finger protein of Drosophila required for expression of Orc4 and S phase. EMBO J (2005) 0.82
New tricks for old dogs: unexpected roles for cell cycle regulators revealed using animal models. Curr Opin Cell Biol (2004) 0.81
Geminin and Brahma act antagonistically to regulate EGFR-Ras-MAPK signaling in Drosophila. Dev Biol (2010) 0.81
Identification of transglutaminase-mediated deamidation sites in a recombinant alpha-gliadin by advanced mass-spectrometric methodologies. Protein Sci (2003) 0.80
A product of the bicistronic Drosophila melanogaster gene CG31241, which also encodes a trimethylguanosine synthase, plays a role in telomere protection. J Cell Sci (2009) 0.79
Death takes a holiday--non-apoptotic role for caspases in cell migration and invasion. EMBO Rep (2013) 0.79
Wingless signaling directly regulates cyclin E expression in proliferating embryonic PNS precursor cells. Mech Dev (2008) 0.77
Making brundlefly, one gene at a time. Cell Res (2009) 0.75
Regulation of Notch signaling and endocytosis by the Lgl neoplastic tumor suppressor. Cell Cycle (2015) 0.75
A screen for genes expressed in the olfactory organs of Drosophila melanogaster identifies genes involved in olfactory behaviour. PLoS One (2012) 0.75
Function of the origin recognition complex 1 (ORC1) outside DNA replication in Drosophila. Cell Cycle (2011) 0.75
PRC2 goes solo in the Drosophila female germline. Dev Cell (2013) 0.75
An orc1 allele with a mutated APC motif is female sterile with amplification defects. Cell Cycle (2012) 0.75