Published in Genetics on August 24, 2007
A program for annotating and predicting the effects of single nucleotide polymorphisms, SnpEff: SNPs in the genome of Drosophila melanogaster strain w1118; iso-2; iso-3. Fly (Austin) (2012) 20.08
Targeted chromosomal deletions in human cells using zinc finger nucleases. Genome Res (2009) 6.24
Genetic manipulation of genes and cells in the nervous system of the fruit fly. Neuron (2011) 2.54
The ribosomal protein genes and Minute loci of Drosophila melanogaster. Genome Biol (2007) 2.40
Using Drosophila melanogaster as a Model for Genotoxic Chemical Mutational Studies with a New Program, SnpSift. Front Genet (2012) 2.21
Targeted gene deletions in C. elegans using transposon excision. Nat Methods (2010) 2.20
An actomyosin-based barrier inhibits cell mixing at compartmental boundaries in Drosophila embryos. Nat Cell Biol (2009) 2.04
Regenerative growth in Drosophila imaginal discs is regulated by Wingless and Myc. Dev Cell (2009) 2.03
Retrotransposon silencing and telomere integrity in somatic cells of Drosophila depends on the cytosine-5 methyltransferase DNMT2. Nat Genet (2009) 1.78
The generation of chromosomal deletions to provide extensive coverage and subdivision of the Drosophila melanogaster genome. Genome Biol (2012) 1.60
Salvador-Warts-Hippo pathway in a developmental checkpoint monitoring helix-loop-helix proteins. Dev Cell (2015) 1.42
Massively parallel resequencing of the isogenic Drosophila melanogaster strain w(1118); iso-2; iso-3 identifies hotspots for mutations in sensory perception genes. Fly (Austin) (2009) 1.41
A role for Acp29AB, a predicted seminal fluid lectin, in female sperm storage in Drosophila melanogaster. Genetics (2008) 1.20
Sir2 mediates apoptosis through JNK-dependent pathways in Drosophila. Proc Natl Acad Sci U S A (2008) 1.19
A molecularly defined duplication set for the X chromosome of Drosophila melanogaster. Genetics (2010) 1.17
Precision of hunchback expression in the Drosophila embryo. Curr Biol (2012) 1.14
Mediation of Drosophila autosomal dosage effects and compensation by network interactions. Genome Biol (2012) 1.11
Quantitative trait loci for aggressive behavior in Drosophila melanogaster. Genetics (2009) 1.08
Genetic screen identifies serpin5 as a regulator of the toll pathway and CHMP2B toxicity associated with frontotemporal dementia. Proc Natl Acad Sci U S A (2009) 1.04
Widespread transcriptional autosomal dosage compensation in Drosophila correlates with gene expression level. Genome Biol Evol (2009) 1.03
Alzheimer's disease: insights from Drosophila melanogaster models. Trends Biochem Sci (2009) 1.03
PP2A-twins is antagonized by greatwall and collaborates with polo for cell cycle progression and centrosome attachment to nuclei in drosophila embryos. PLoS Genet (2011) 1.02
Drosophila mitoferrin is essential for male fertility: evidence for a role of mitochondrial iron metabolism during spermatogenesis. BMC Dev Biol (2010) 0.99
A new resource for characterizing X-linked genes in Drosophila melanogaster: systematic coverage and subdivision of the X chromosome with nested, Y-linked duplications. Genetics (2010) 0.97
Drosophila CK1-γ, gilgamesh, controls PCP-mediated morphogenesis through regulation of vesicle trafficking. J Cell Biol (2012) 0.97
A Drosophila genetic screen yields allelic series of core microRNA biogenesis factors and reveals post-developmental roles for microRNAs. RNA (2011) 0.96
Drosophila, genetic screens, and cardiac function. Circ Res (2011) 0.95
A genome-wide screen reveals a role for microRNA-1 in modulating cardiac cell polarity. Dev Cell (2011) 0.93
Gene expression following induction of regeneration in Drosophila wing imaginal discs. Expression profile of regenerating wing discs. BMC Dev Biol (2010) 0.91
A screen for round egg mutants in Drosophila identifies tricornered, furry, and misshapen as regulators of egg chamber elongation. G3 (Bethesda) (2012) 0.91
A small genomic region containing several loci required for gastrulation in Drosophila. PLoS One (2009) 0.90
pubmed2ensembl: a resource for mining the biological literature on genes. PLoS One (2011) 0.89
New research resources at the Bloomington Drosophila Stock Center. Fly (Austin) (2010) 0.89
Genetic variation in a member of the laminin gene family affects variation in body composition in Drosophila and humans. BMC Genet (2008) 0.89
Buffering and proteolysis are induced by segmental monosomy in Drosophila melanogaster. Nucleic Acids Res (2012) 0.88
dEHBP1 controls exocytosis and recycling of Delta during asymmetric divisions. J Cell Biol (2012) 0.88
Rab8, POSH, and TAK1 regulate synaptic growth in a Drosophila model of frontotemporal dementia. J Cell Biol (2015) 0.87
A simple and rapid method for constructing ring-X chromosomes in Drosophila melanogaster. Chromosoma (2010) 0.86
Evaluation of the role of functional constraints on the integrity of an ultraconserved region in the genus Drosophila. PLoS Genet (2012) 0.86
Specification of Drosophila corpora cardiaca neuroendocrine cells from mesoderm is regulated by Notch signaling. PLoS Genet (2011) 0.86
Exploiting Drosophila genetics to understand microRNA function and regulation. Curr Top Dev Biol (2012) 0.85
WNT5 interacts with the Ryk receptors doughnut and derailed to mediate muscle attachment site selection in Drosophila melanogaster. PLoS One (2012) 0.84
Chemical mutagens, transposons, and transgenes to interrogate gene function in Drosophila melanogaster. Methods (2014) 0.84
Introgression of Drosophila simulans nuclear pore protein 160 in Drosophila melanogaster alone does not cause inviability but does cause female sterility. Genetics (2010) 0.83
The kinesin-3, unc-104 regulates dendrite morphogenesis and synaptic development in Drosophila. Genetics (2013) 0.83
Genetic and functional studies implicate synaptic overgrowth and ring gland cAMP/PKA signaling defects in the Drosophila melanogaster neurofibromatosis-1 growth deficiency. PLoS Genet (2013) 0.83
Transcriptional regulation by CHIP/LDB complexes. PLoS Genet (2010) 0.83
Functional analysis of PGRP-LA in Drosophila immunity. PLoS One (2013) 0.82
Neighbourhood continuity is not required for correct testis gene expression in Drosophila. PLoS Biol (2010) 0.82
Removal of the bloom syndrome DNA helicase extends the utility of imprecise transposon excision for making null mutations in Drosophila. Genetics (2009) 0.82
Localization and characteristics of DNA underreplication zone in the 75C region of intercalary heterochromatin in Drosophila melanogaster polytene chromosomes. Chromosoma (2009) 0.81
Cardiomyopathy is associated with ribosomal protein gene haplo-insufficiency in Drosophila melanogaster. Genetics (2011) 0.81
Toward a complete Drosophila deficiency kit. Genome Biol (2012) 0.81
X Chromosome and Autosome Dosage Responses in Drosophila melanogaster Heads. G3 (Bethesda) (2015) 0.81
Degradation of Gadd45 mRNA by nonsense-mediated decay is essential for viability. Elife (2016) 0.81
Neuronal remodeling during metamorphosis is regulated by the alan shepard (shep) gene in Drosophila melanogaster. Genetics (2014) 0.81
Drosophila mutants show NMD pathway activity is reduced, but not eliminated, in the absence of Smg6. RNA (2012) 0.80
The Convergence of Systems and Reductionist Approaches in Complex Trait Analysis. Cell (2015) 0.80
Novel regulators of planar cell polarity: a genetic analysis in Drosophila. Genetics (2012) 0.80
Slmb antagonises the aPKC/Par-6 complex to control oocyte and epithelial polarity. Development (2014) 0.80
Exploring prion protein biology in flies: genetics and beyond. Prion (2010) 0.80
Identifying cellular pathways modulated by Drosophila palmitoyl-protein thioesterase 1 function. Neurobiol Dis (2010) 0.80
The Drosophila melanogaster Mutants apblot and apXasta Affect an Essential apterous Wing Enhancer. G3 (Bethesda) (2015) 0.79
Genetic aspects of behavioral neurotoxicology. Neurotoxicology (2009) 0.79
Construction and characterization of deletions with defined end points in Drosophila using P elements in trans. Genetics (2008) 0.79
Genetic correlation between the pre-adult developmental period and locomotor activity rhythm in Drosophila melanogaster. Heredity (Edinb) (2012) 0.79
Eye development. Methods (2014) 0.78
The ADAR RNA editing enzyme controls neuronal excitability in Drosophila melanogaster. Nucleic Acids Res (2013) 0.78
Rapid recombination mapping for high-throughput genetic screens in Drosophila. G3 (Bethesda) (2013) 0.78
Mitochondrial iron supply is required for the developmental pulse of ecdysone biosynthesis that initiates metamorphosis in Drosophila melanogaster. J Biol Inorg Chem (2015) 0.78
Dual Roles of O-Glucose Glycans Redundant with Monosaccharide O-Fucose on Notch in Notch Trafficking. J Biol Chem (2016) 0.77
Drosophila and genome-wide association studies: a review and resource for the functional dissection of human complex traits. Dis Model Mech (2017) 0.77
Genome engineering: Drosophila melanogaster and beyond. Wiley Interdiscip Rev Dev Biol (2015) 0.77
Effect of genomic deficiencies on sexual size dimorphism through modification of developmental time in Drosophila melanogaster. Heredity (Edinb) (2015) 0.77
Dendritic diversification through transcription factor-mediated suppression of alternative morphologies. Development (2016) 0.76
An assay to detect in vivo Y chromosome loss in Drosophila wing disc cells. G3 (Bethesda) (2012) 0.76
Large-scale functional annotation and expanded implementations of the P{wHy} hybrid transposon in the Drosophila melanogaster genome. Genetics (2009) 0.76
Genome-wide deficiency screen for the genomic regions responsible for heat resistance in Drosophila melanogaster. BMC Genet (2011) 0.76
Invadolysin acts genetically via the SAGA complex to modulate chromosome structure. Nucleic Acids Res (2015) 0.75
Genetic Screen in Drosophila Larvae Links ird1 Function to Toll Signaling in the Fat Body and Hemocyte Motility. PLoS One (2016) 0.75
The wavy Mutation Maps to the Inositol 1,4,5-Trisphosphate 3-Kinase 2 (IP3K2) Gene of Drosophila and Interacts with IP3R to Affect Wing Development. G3 (Bethesda) (2015) 0.75
Effects of Gene Dose, Chromatin, and Network Topology on Expression in Drosophila melanogaster. PLoS Genet (2016) 0.75
Cardiolipin promotes electron transport between ubiquinone and complex I to rescue PINK1 deficiency. J Cell Biol (2017) 0.75
The BLOC-1 Subunit Pallidin Facilitates Activity-Dependent Synaptic Vesicle Recycling. eNeuro (2017) 0.75
A strategy for generation and balancing of autosome: Y chromosome translocations. Fly (Austin) (2014) 0.75
The postsynaptic t-SNARE Syntaxin 4 controls traffic of Neuroligin 1 and Synaptotagmin 4 to regulate retrograde signaling. Elife (2016) 0.75
A Novel Frizzled-Based Screening Tool Identifies Genetic Modifiers of Planar Cell Polarity in Drosophila Wings. G3 (Bethesda) (2016) 0.75
Signaling by the engulfment receptor draper: a screen in Drosophila melanogaster implicates cytoskeletal regulators, Jun N-terminal Kinase, and Yorkie. Genetics (2014) 0.75
Insights into ALS pathomechanisms: from flies to humans. Fly (Austin) (2015) 0.75
Cardiomyocyte Regulation of Systemic Lipid Metabolism by the Apolipoprotein B-Containing Lipoproteins in Drosophila. PLoS Genet (2017) 0.75
Primer3 on the WWW for general users and for biologist programmers. Methods Mol Biol (2000) 128.08
The Effects of Unequal Crossing over at the Bar Locus in Drosophila. Genetics (1925) 30.11
A complementary transposon tool kit for Drosophila melanogaster using P and piggyBac. Nat Genet (2004) 8.55
Systematic generation of high-resolution deletion coverage of the Drosophila melanogaster genome. Nat Genet (2004) 8.24
Gene discovery using computational and microarray analysis of transcription in the Drosophila melanogaster testis. Genome Res (2000) 3.98
The DrosDel collection: a set of P-element insertions for generating custom chromosomal aberrations in Drosophila melanogaster. Genetics (2004) 3.71
Variation within and among species in gene expression: raw material for evolution. Mol Ecol (2006) 3.36
"Site-selected" transposon mutagenesis of Drosophila. Proc Natl Acad Sci U S A (1990) 2.90
The minute genes in Drosophila and their molecular functions. Adv Genet (1998) 2.57
Engineering the Drosophila genome: chromosome rearrangements by design. Genetics (1996) 2.23
INTRACHROMOSOMAL EXCHANGE AT THE BAR LOCUS IN DROSOPHILA. Proc Natl Acad Sci U S A (1963) 1.68
Unequal crossing-over within the B duplication of Drosophila melanogaster: a molecular analysis. Genet Res (1991) 0.99
Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells. Nat Cell Biol (2007) 37.10
The OBO Foundry: coordinated evolution of ontologies to support biomedical data integration. Nat Biotechnol (2007) 35.41
The minimum information about a genome sequence (MIGS) specification. Nat Biotechnol (2008) 31.04
The Sequence Ontology: a tool for the unification of genome annotations. Genome Biol (2005) 18.20
ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res (2007) 13.08
Promoting coherent minimum reporting guidelines for biological and biomedical investigations: the MIBBI project. Nat Biotechnol (2008) 12.96
Identification of functional elements and regulatory circuits by Drosophila modENCODE. Science (2010) 12.39
FlyBase: enhancing Drosophila Gene Ontology annotations. Nucleic Acids Res (2008) 12.15
An ontology for cell types. Genome Biol (2005) 11.71
Systematic determination of patterns of gene expression during Drosophila embryogenesis. Genome Biol (2002) 8.89
A silencing pathway to induce H3-K9 and H4-K20 trimethylation at constitutive heterochromatin. Genes Dev (2004) 8.66
Annotation of the Drosophila melanogaster euchromatic genome: a systematic review. Genome Biol (2002) 8.59
Assessment of genome-wide protein function classification for Drosophila melanogaster. Genome Res (2003) 8.39
Regulation of mTOR function in response to hypoxia by REDD1 and the TSC1/TSC2 tumor suppressor complex. Genes Dev (2004) 7.51
Calling on a million minds for community annotation in WikiProteins. Genome Biol (2008) 7.11
EGASP: the human ENCODE Genome Annotation Assessment Project. Genome Biol (2006) 7.06
Insulin activation of Rheb, a mediator of mTOR/S6K/4E-BP signaling, is inhibited by TSC1 and 2. Mol Cell (2003) 6.76
Heterogeneity of breast cancer associations with five susceptibility loci by clinical and pathological characteristics. PLoS Genet (2008) 6.22
The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective. Genome Biol (2002) 5.80
Central role of Drosophila SU(VAR)3-9 in histone H3-K9 methylation and heterochromatic gene silencing. EMBO J (2002) 5.70
Kremen proteins are Dickkopf receptors that regulate Wnt/beta-catenin signalling. Nature (2002) 5.61
Gadd45a promotes epigenetic gene activation by repair-mediated DNA demethylation. Nature (2007) 5.54
Integrating phenotype ontologies across multiple species. Genome Biol (2010) 5.46
The bacterial symbiont Wolbachia induces resistance to RNA viral infections in Drosophila melanogaster. PLoS Biol (2008) 5.42
Longer lifespan, altered metabolism, and stress resistance in Drosophila from ablation of cells making insulin-like ligands. Proc Natl Acad Sci U S A (2005) 5.34
FlyMine: an integrated database for Drosophila and Anopheles genomics. Genome Biol (2007) 5.23
Linking human diseases to animal models using ontology-based phenotype annotation. PLoS Biol (2009) 5.17
Nutrient-dependent expression of insulin-like peptides from neuroendocrine cells in the CNS contributes to growth regulation in Drosophila. Curr Biol (2002) 5.12
A locus on 19p13 modifies risk of breast cancer in BRCA1 mutation carriers and is associated with hormone receptor-negative breast cancer in the general population. Nat Genet (2010) 4.96
Integration with the human genome of peptide sequences obtained by high-throughput mass spectrometry. Genome Biol (2004) 4.91
The Drosophila forkhead transcription factor FOXO mediates the reduction in cell number associated with reduced insulin signaling. J Biol (2003) 4.85
A cis-regulatory map of the Drosophila genome. Nature (2011) 4.80
Long-lived Drosophila with overexpressed dFOXO in adult fat body. Science (2004) 4.70
Insulin/IGF and target of rapamycin signaling: a TOR de force in growth control. Trends Cell Biol (2003) 4.67
Associations of breast cancer risk factors with tumor subtypes: a pooled analysis from the Breast Cancer Association Consortium studies. J Natl Cancer Inst (2010) 4.54
Drosophila crinkled, mutations of which disrupt morphogenesis and cause lethality, encodes fly myosin VIIA. Genetics (2004) 4.51
Rheb is an essential regulator of S6K in controlling cell growth in Drosophila. Nat Cell Biol (2003) 4.20
National Center for Biomedical Ontology: advancing biomedicine through structured organization of scientific knowledge. OMICS (2006) 3.96
The DrosDel collection: a set of P-element insertions for generating custom chromosomal aberrations in Drosophila melanogaster. Genetics (2004) 3.71
Dietary restriction in long-lived dwarf flies. Science (2002) 3.71
Phenotype ontologies: the bridge between genomics and evolution. Trends Ecol Evol (2007) 3.68
The hypoxia-induced paralogs Scylla and Charybdis inhibit growth by down-regulating S6K activity upstream of TSC in Drosophila. Genes Dev (2004) 3.59
A high-quality catalog of the Drosophila melanogaster proteome. Nat Biotechnol (2007) 3.34
A comprehensive map of insulator elements for the Drosophila genome. PLoS Genet (2010) 3.25
Su(var) genes regulate the balance between euchromatin and heterochromatin in Drosophila. Genes Dev (2004) 3.08
Prickle mediates feedback amplification to generate asymmetric planar cell polarity signaling. Cell (2002) 3.03
Human saliva, plasma and breast milk exosomes contain RNA: uptake by macrophages. J Transl Med (2011) 3.03
Cancer incidence in a population-based cohort of individuals hospitalized with celiac disease or dermatitis herpetiformis. Gastroenterology (2002) 2.94
A rapidly evolving MYB-related protein causes species isolation in Drosophila. Proc Natl Acad Sci U S A (2003) 2.89
Low penetrance breast cancer susceptibility loci are associated with specific breast tumor subtypes: findings from the Breast Cancer Association Consortium. Hum Mol Genet (2011) 2.72
Heterochromatin formation in Drosophila is initiated through active removal of H3K4 methylation by the LSD1 homolog SU(VAR)3-3. Mol Cell (2007) 2.66
Improving reproducibility and sensitivity in identifying human proteins by shotgun proteomics. Anal Chem (2004) 2.53
Drosophila egg-laying site selection as a system to study simple decision-making processes. Science (2008) 2.50
Combined evidence annotation of transposable elements in genome sequences. PLoS Comput Biol (2005) 2.47
The ribosomal protein genes and Minute loci of Drosophila melanogaster. Genome Biol (2007) 2.40
Position-effect variegation and the genetic dissection of chromatin regulation in Drosophila. Semin Cell Dev Biol (2003) 2.37
The WW domain protein Kibra acts upstream of Hippo in Drosophila. Dev Cell (2010) 2.34
dS6K-regulated cell growth is dPKB/dPI(3)K-independent, but requires dPDK1. Nat Cell Biol (2002) 2.31
Histone modification and the control of heterochromatic gene silencing in Drosophila. Chromosome Res (2006) 2.28
Identification and functional characterization of N-terminally acetylated proteins in Drosophila melanogaster. PLoS Biol (2009) 2.25
Entity/quality-based logical definitions for the human skeletal phenome using PATO. Conf Proc IEEE Eng Med Biol Soc (2009) 2.20
CTCF genomic binding sites in Drosophila and the organisation of the bithorax complex. PLoS Genet (2007) 2.12
Living with lethal PIP3 levels: viability of flies lacking PTEN restored by a PH domain mutation in Akt/PKB. Science (2002) 2.05
Pivotal role of AtSUVH2 in heterochromatic histone methylation and gene silencing in Arabidopsis. EMBO J (2005) 2.04
A 1-megadalton ESC/E(Z) complex from Drosophila that contains polycomblike and RPD3. Mol Cell Biol (2003) 2.03
Glutaminyl cyclase inhibition attenuates pyroglutamate Abeta and Alzheimer's disease-like pathology. Nat Med (2008) 2.01
Fisherfolk are among groups most at risk of HIV: cross-country analysis of prevalence and numbers infected. AIDS (2005) 2.01
A novel, evolutionarily conserved protein phosphatase complex involved in cisplatin sensitivity. Mol Cell Proteomics (2005) 1.95
Reduction of DILP2 in Drosophila triages a metabolic phenotype from lifespan revealing redundancy and compensation among DILPs. PLoS One (2008) 1.95