Published in Br J Haematol on March 12, 2008
Seventy-five genetic loci influencing the human red blood cell. Nature (2012) 2.77
Malaria parasite proteins that remodel the host erythrocyte. Nat Rev Microbiol (2009) 2.62
High shear-dependent loss of membrane integrity and defective platelet adhesion following disruption of the GPIbα-filamin interaction. Blood (2010) 1.75
Molecular physiology and genetics of Na+-independent SLC4 anion exchangers. J Exp Biol (2009) 1.50
Targeted deletion of alpha-adducin results in absent beta- and gamma-adducin, compensated hemolytic anemia, and lethal hydrocephalus in mice. Blood (2008) 1.32
Piezo1 plays a role in erythrocyte volume homeostasis. Haematologica (2013) 1.29
The spectrin-ankyrin-4.1-adducin membrane skeleton: adapting eukaryotic cells to the demands of animal life. Protoplasma (2010) 1.26
AMPKalpha1 deletion shortens erythrocyte life span in mice: role of oxidative stress. J Biol Chem (2010) 1.19
Investigating the key membrane protein changes during in vitro erythropoiesis of protein 4.2 (-) cells (mutations Chartres 1 and 2). Haematologica (2010) 1.12
Imaging of the diffusion of single band 3 molecules on normal and mutant erythrocytes. Blood (2009) 1.12
Native ultrastructure of the red cell cytoskeleton by cryo-electron tomography. Biophys J (2011) 1.11
Blood rheology and aging. J Geriatr Cardiol (2013) 1.00
Diffusion in a fluid membrane with a flexible cortical cytoskeleton. Biophys J (2009) 0.97
Malaria: modification of the red blood cell and consequences in the human host. Br J Haematol (2011) 0.96
Survival of red blood cells after transfusion: processes and consequences. Front Physiol (2013) 0.94
4.1R-deficient human red blood cells have altered phosphatidylserine exposure pathways and are deficient in CD44 and CD47 glycoproteins. Haematologica (2009) 0.92
Multiple stiffening effects of nanoscale knobs on human red blood cells infected with Plasmodium falciparum malaria parasite. Proc Natl Acad Sci U S A (2015) 0.91
A Review of Cell Adhesion Studies for Biomedical and Biological Applications. Int J Mol Sci (2015) 0.91
Refined views of multi-protein complexes in the erythrocyte membrane. Blood Cells Mol Dis (2012) 0.90
Interaction of Plasmodium falciparum knob-associated histidine-rich protein (KAHRP) with erythrocyte ankyrin R is required for its attachment to the erythrocyte membrane. Biochim Biophys Acta (2013) 0.88
Blood Groups in Infection and Host Susceptibility. Clin Microbiol Rev (2015) 0.88
Biomechanical properties of red blood cells in health and disease towards microfluidics. Biomicrofluidics (2014) 0.87
Erythrocyte membrane model with explicit description of the lipid bilayer and the spectrin network. Biophys J (2014) 0.87
Heterogeneous red blood cell adhesion and deformability in sickle cell disease. Sci Rep (2014) 0.87
Depletion of hemoglobin and carbonic anhydrase from erythrocyte cytosolic samples by preparative clear native electrophoresis. Nat Protoc (2011) 0.86
Changes in band 3 structure as determinants of erythrocyte integrity during storage and survival after transfusion. Blood Transfus (2010) 0.84
The cytoskeletal binding domain of band 3 is required for multiprotein complex formation and retention during erythropoiesis. Haematologica (2014) 0.83
Beta-spectrinBari: a truncated beta-chain responsible for dominant hereditary spherocytosis. Haematologica (2009) 0.83
Delivery of drugs bound to erythrocytes: new avenues for an old intravascular carrier. Ther Deliv (2015) 0.81
Zebrafish erythropoiesis and the utility of fish as models of anemia. Stem Cell Res Ther (2012) 0.80
Computational biomechanics of human red blood cells in hematological disorders. J Biomech Eng (2016) 0.80
Diagnostic tool for red blood cell membrane disorders: Assessment of a new generation ektacytometer. Blood Cells Mol Dis (2015) 0.79
Analysis of novel sph (spherocytosis) alleles in mice reveals allele-specific loss of band 3 and adducin in alpha-spectrin-deficient red cells. Blood (2010) 0.79
Genome wide association analysis of a founder population identified TAF3 as a gene for MCHC in humans. PLoS One (2013) 0.78
Abnormal erythroid maturation leads to microcytic anemia in the TSAP6/Steap3 null mouse model. Am J Hematol (2015) 0.78
Repository of Human Blood Derivative Biospecimens in Biobank: Technical Implications. Middle East J Dig Dis (2015) 0.77
Reduced erythrocyte deformability associated with hypoargininemia during Plasmodium falciparum malaria. Sci Rep (2014) 0.77
Cardiac cytoskeleton and arrhythmia: an unexpected role for protein 4.1R in cardiac excitability. Circ Res (2008) 0.77
Characterization of ENU-induced Mutations in Red Blood Cell Structural Proteins. Comput Struct Biotechnol J (2013) 0.77
A novel strain energy relationship for red blood cell membrane skeleton based on spectrin stiffness and its application to micropipette deformation. Biomech Model Mechanobiol (2015) 0.77
Acanthocytosis and the c.680 A>G Mutation in the PANK2 Gene: A Study Enrolling a Cohort of PKAN Patients from the Dominican Republic. PLoS One (2015) 0.77
MD/DPD Multiscale Framework for Predicting Morphology and Stresses of Red Blood Cells in Health and Disease. PLoS Comput Biol (2016) 0.76
Functional analysis of a novel cis-acting regulatory region within the human ankyrin gene (ANK-1) promoter. Mol Cell Biol (2010) 0.76
The potential role of cell penetrating peptides in the intracellular delivery of proteins for therapy of erythroid related disorders. Pharmaceuticals (Basel) (2013) 0.76
Genotype-phenotype correlations in hereditary elliptocytosis and hereditary pyropoikilocytosis. Blood Cells Mol Dis (2016) 0.75
Spectrin Tunis (Sp alpha (I/78)) in a Korean family with hereditary elliptocytosis. Ann Lab Med (2013) 0.75
Hemolytic anemia repressed hepcidin level without hepatocyte iron overload: lesson from Günther disease model. Haematologica (2016) 0.75
The sorting of blood group active proteins during enucleation. ISBT Sci Ser (2015) 0.75
Pulmonary arterial hypertension associated with hereditary spherocytosis and splenectomy in a patient with a mutation in the BMPR2 gene. Clin Case Rep (2016) 0.75
Emerging point-of-care technologies for sickle cell disease screening and monitoring. Expert Rev Med Devices (2016) 0.75
Biological Databases for Hematology Research. Genomics Proteomics Bioinformatics (2016) 0.75
Stability of eosin-5'-maleimide dye used in flow cytometric analysis for red cell membrane disorders. Blood Res (2015) 0.75
Neuroacanthocytosis: Observations, Theories and Perspectives on the Origin and Significance of Acanthocytes. Tremor Other Hyperkinet Mov (N Y) (2015) 0.75
Hematological disorders and pulmonary hypertension. World J Cardiol (2016) 0.75
Diagnostic approaches for inherited hemolytic anemia in the genetic era. Blood Res (2017) 0.75
Comprehensive characterization of protein 4.1 expression in epithelium of large intestine. Histochem Cell Biol (2014) 0.75
Resolving the distinct stages in erythroid differentiation based on dynamic changes in membrane protein expression during erythropoiesis. Proc Natl Acad Sci U S A (2009) 3.00
Erythroblastic islands: niches for erythropoiesis. Blood (2008) 2.93
Primary role for adherent leukocytes in sickle cell vascular occlusion: a new paradigm. Proc Natl Acad Sci U S A (2002) 2.72
Hereditary spherocytosis. Lancet (2008) 2.37
A band 3-based macrocomplex of integral and peripheral proteins in the RBC membrane. Blood (2003) 2.24
Hepcidin as a therapeutic tool to limit iron overload and improve anemia in β-thalassemic mice. J Clin Invest (2010) 2.18
Protein 4.1R-dependent multiprotein complex: new insights into the structural organization of the red blood cell membrane. Proc Natl Acad Sci U S A (2008) 2.18
Hypoxia-induced acute lung injury in murine models of sickle cell disease. Am J Physiol Lung Cell Mol Physiol (2003) 2.08
Contribution of parasite proteins to altered mechanical properties of malaria-infected red blood cells. Blood (2002) 1.93
The dendritic cell receptor Clec9A binds damaged cells via exposed actin filaments. Immunity (2012) 1.89
A transgenic mouse model demonstrates a dominant negative effect of a point mutation in the RPS19 gene associated with Diamond-Blackfan anemia. Blood (2010) 1.88
Quantitative assessment of sensing and sequestration of spherocytic erythrocytes by the human spleen. Blood (2012) 1.87
Hereditary spherocytosis and hereditary elliptocytosis: aberrant protein sorting during erythroblast enucleation. Blood (2010) 1.81
A Maurer's cleft-associated protein is essential for expression of the major malaria virulence antigen on the surface of infected red blood cells. J Cell Biol (2006) 1.73
The spectrin-based membrane skeleton stabilizes mouse megakaryocyte membrane systems and is essential for proplatelet and platelet formation. Blood (2011) 1.67
Targeted gene deletion demonstrates that the cell adhesion molecule ICAM-4 is critical for erythroblastic island formation. Blood (2006) 1.63
Cytoskeletal protein 4.1R negatively regulates T-cell activation by inhibiting the phosphorylation of LAT. Blood (2009) 1.57
Malaria and the red blood cell membrane. Semin Hematol (2004) 1.54
Identification of a functional role for lipid asymmetry in biological membranes: Phosphatidylserine-skeletal protein interactions modulate membrane stability. Proc Natl Acad Sci U S A (2002) 1.53
Modulation of erythrocyte membrane mechanical function by protein 4.1 phosphorylation. J Biol Chem (2004) 1.53
Mechanism of protein sorting during erythroblast enucleation: role of cytoskeletal connectivity. Blood (2003) 1.52
The sensing of poorly deformable red blood cells by the human spleen can be mimicked in vitro. Blood (2010) 1.52
Membrane remodeling during reticulocyte maturation. Blood (2009) 1.47
Shear-response of the spectrin dimer-tetramer equilibrium in the red blood cell membrane. J Biol Chem (2002) 1.46
Malaria, erythrocytic infection, and anemia. Hematology Am Soc Hematol Educ Program (2009) 1.44
The ring-infected erythrocyte surface antigen (RESA) of Plasmodium falciparum stabilizes spectrin tetramers and suppresses further invasion. Blood (2007) 1.42
Red blood cell blood group antigens: structure and function. Semin Hematol (2004) 1.42
Adducin forms a bridge between the erythrocyte membrane and its cytoskeleton and regulates membrane cohesion. Blood (2009) 1.42
Rac GTPases regulate the morphology and deformability of the erythrocyte cytoskeleton. Blood (2006) 1.41
Structural and functional studies of interaction between Plasmodium falciparum knob-associated histidine-rich protein (KAHRP) and erythrocyte spectrin. J Biol Chem (2005) 1.41
Quantitative analysis of murine terminal erythroid differentiation in vivo: novel method to study normal and disordered erythropoiesis. Blood (2013) 1.39
Fluctuations of the red blood cell membrane: relation to mechanical properties and lack of ATP dependence. Biophys J (2008) 1.38
Erythrocyte remodeling by malaria parasites. Curr Opin Hematol (2007) 1.37
Lineage and species-specific long noncoding RNAs during erythro-megakaryocytic development. Blood (2014) 1.34
Racial differences in human platelet PAR4 reactivity reflect expression of PCTP and miR-376c. Nat Med (2013) 1.34
Targeted deletion of alpha-adducin results in absent beta- and gamma-adducin, compensated hemolytic anemia, and lethal hydrocephalus in mice. Blood (2008) 1.32
The hydration state of human red blood cells and their susceptibility to invasion by Plasmodium falciparum. Blood (2005) 1.32
Erythrocyte G protein as a novel target for malarial chemotherapy. PLoS Med (2006) 1.31
Erythrocyte G protein-coupled receptor signaling in malarial infection. Science (2003) 1.31
Conformational stabilities of the structural repeats of erythroid spectrin and their functional implications. J Biol Chem (2006) 1.29
Erythrocyte detergent-resistant membrane proteins: their characterization and selective uptake during malarial infection. Blood (2003) 1.26
Hereditary spherocytosis, elliptocytosis, and other red cell membrane disorders. Blood Rev (2013) 1.26
Characterization of glycolytic enzyme interactions with murine erythrocyte membranes in wild-type and membrane protein knockout mice. Blood (2008) 1.23
Ribosomal protein S19 expression during erythroid differentiation. Blood (2002) 1.20
Cytoskeletal protein 4.1R affects repolarization and regulates calcium handling in the heart. Circ Res (2008) 1.17
Study of the effects of proteasome inhibitors on ribosomal protein S19 (RPS19) mutants, identified in patients with Diamond-Blackfan anemia. Haematologica (2008) 1.16
Significant biochemical, biophysical and metabolic diversity in circulating human cord blood reticulocytes. PLoS One (2013) 1.15
The contribution of endothelial cell P-selectin to the microvascular flow of mouse sickle erythrocytes in vivo. Blood (2004) 1.15
Functional characterization of spectrin-actin-binding domains in 4.1 family of proteins. Biochemistry (2002) 1.15
Nuclear substructure reorganization during late-stage erythropoiesis is selective and does not involve caspase cleavage of major nuclear substructural proteins. Blood (2005) 1.15
Identification and functional characterization of protein 4.1R and actin-binding sites in erythrocyte beta spectrin: regulation of the interactions by phosphatidylinositol-4,5-bisphosphate. Biochemistry (2005) 1.13
A dynamic alternative splicing program regulates gene expression during terminal erythropoiesis. Nucleic Acids Res (2014) 1.13
Plasmodium falciparum erythrocyte membrane protein 3 (PfEMP3) destabilizes erythrocyte membrane skeleton. J Biol Chem (2007) 1.12
Sickle red cell microrheology and sickle blood rheology. Microcirculation (2004) 1.12
Native ultrastructure of the red cell cytoskeleton by cryo-electron tomography. Biophys J (2011) 1.11
Phosphatidylserine binding sites in erythroid spectrin: location and implications for membrane stability. Biochemistry (2004) 1.10
Functional alteration of red blood cells by a megadalton protein of Plasmodium falciparum. Blood (2008) 1.09
Distinct distribution of specific members of protein 4.1 gene family in the mouse nephron. Kidney Int (2003) 1.07
Lamins regulate cell trafficking and lineage maturation of adult human hematopoietic cells. Proc Natl Acad Sci U S A (2013) 1.06
Mammalian alpha I-spectrin is a neofunctionalized polypeptide adapted to small highly deformable erythrocytes. Proc Natl Acad Sci U S A (2006) 1.06
Mapping the domains of the cytoadherence ligand Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) that bind to the knob-associated histidine-rich protein (KAHRP). Mol Biochem Parasitol (2002) 1.05
Stomatin and sensory neuron mechanotransduction. J Neurophysiol (2007) 1.05
A Golgi-associated protein 4.1B variant is required for assimilation of proteins in the membrane. J Cell Sci (2009) 1.04
Tropomyosin modulates erythrocyte membrane stability. Blood (2006) 1.03
Assignment of functional roles to parasite proteins in malaria-infected red blood cells by competitive flow-based adhesion assay. Br J Haematol (2002) 1.03
The N-terminal 11 amino acids of human erythrocyte band 3 are critical for aldolase binding and protein phosphorylation: implications for band 3 function. Blood (2005) 1.02
Interactions of Plasmodium falciparum erythrocyte membrane protein 3 with the red blood cell membrane skeleton. Biochim Biophys Acta (2007) 1.02
Comparison of mechanisms of anemia in mice with sickle cell disease and beta-thalassemia: peripheral destruction, ineffective erythropoiesis, and phospholipid scramblase-mediated phosphatidylserine exposure. Exp Hematol (2002) 1.01
Lipid rafts and malaria parasite infection of erythrocytes. Mol Membr Biol (2006) 1.01
Intrasplicing coordinates alternative first exons with alternative splicing in the protein 4.1R gene. EMBO J (2007) 1.01
Peptides based on alphaV-binding domains of erythrocyte ICAM-4 inhibit sickle red cell-endothelial interactions and vaso-occlusion in the microcirculation. Am J Physiol Cell Physiol (2006) 1.00
Protein and lipid trafficking induced in erythrocytes infected by malaria parasites. Cell Microbiol (2002) 1.00
Protein 4.1R links E-cadherin/beta-catenin complex to the cytoskeleton through its direct interaction with beta-catenin and modulates adherens junction integrity. Biochim Biophys Acta (2009) 0.99
Red cell indices in classification and treatment of anemias: from M.M. Wintrobes's original 1934 classification to the third millennium. Curr Opin Hematol (2013) 0.99
Resveratrol accelerates erythroid maturation by activation of FoxO3 and ameliorates anemia in beta-thalassemic mice. Haematologica (2013) 0.99
Erythrocyte NADPH oxidase activity modulated by Rac GTPases, PKC, and plasma cytokines contributes to oxidative stress in sickle cell disease. Blood (2013) 0.98
Erythrocyte membrane changes of chorea-acanthocytosis are the result of altered Lyn kinase activity. Blood (2011) 0.98
Alternative 5' exons and differential splicing regulate expression of protein 4.1R isoforms with distinct N-termini. Blood (2003) 0.97
Phosphatidylinositol-4,5-biphosphate (PIP2) differentially regulates the interaction of human erythrocyte protein 4.1 (4.1R) with membrane proteins. Biochemistry (2006) 0.97
High frequency of alternative first exons in erythroid genes suggests a critical role in regulating gene function. Blood (2005) 0.96
Differential domain evolution and complex RNA processing in a family of paralogous EPB41 (protein 4.1) genes facilitate expression of diverse tissue-specific isoforms. Genomics (2004) 0.96
Efficient in vivo manipulation of alternative pre-mRNA splicing events using antisense morpholinos in mice. J Biol Chem (2010) 0.95
Thermal stabilities of brain spectrin and the constituent repeats of subunits. Biochemistry (2006) 0.95
Detection of detergent-resistant membranes in asexual blood-stage parasites of Plasmodium falciparum. Mol Biochem Parasitol (2003) 0.95
Identification of critical amino-acid residues on the erythroid intercellular adhesion molecule-4 (ICAM-4) mediating adhesion to alpha V integrins. Blood (2003) 0.94
Membrane assembly during erythropoiesis. Curr Opin Hematol (2011) 0.94
Altered phosphorylation of cytoskeleton proteins in sickle red blood cells: the role of protein kinase C, Rac GTPases, and reactive oxygen species. Blood Cells Mol Dis (2010) 0.94
Membrane peroxidation and methemoglobin formation are both necessary for band 3 clustering: mechanistic insights into human erythrocyte senescence. Biochemistry (2013) 0.93
Surface area loss and increased sphericity account for the splenic entrapment of subpopulations of Plasmodium falciparum ring-infected erythrocytes. PLoS One (2013) 0.93
Dusty protein kinases: primary structure, gene evolution, tissue specific expression and unique features of the catalytic domain. Biochim Biophys Acta (2006) 0.93
Cytoplasmic remodeling of erythrocyte raft lipids during infection by the human malaria parasite Plasmodium falciparum. Blood (2007) 0.92
Lack of protein 4.1G causes altered expression and localization of the cell adhesion molecule nectin-like 4 in testis and can cause male infertility. Mol Cell Biol (2011) 0.92
Integral protein linkage and the bilayer-skeletal separation energy in red blood cells. Biophys J (2008) 0.92
Control of erythrocyte membrane-skeletal cohesion by the spectrin-membrane linkage. Biochemistry (2010) 0.91
Identification of a third Protein 4.1 tumor suppressor, Protein 4.1R, in meningioma pathogenesis. Neurobiol Dis (2003) 0.91
Deletion of a malaria invasion gene reduces death and anemia, in model hosts. PLoS One (2011) 0.91
The water channel aquaporin-1 partitions into exosomes during reticulocyte maturation: implication for the regulation of cell volume. Blood (2009) 0.90