Published in Blood on November 17, 2005
Erythroid Krüppel-like factor directly activates the basic Krüppel-like factor gene in erythroid cells. Mol Cell Biol (2007) 1.45
Alternative pre-mRNA splicing switches modulate gene expression in late erythropoiesis. Blood (2009) 1.25
Cold-inducible RNA binding protein (CIRP) expression is modulated by alternative mRNAs. RNA (2009) 1.13
Intrasplicing coordinates alternative first exons with alternative splicing in the protein 4.1R gene. EMBO J (2007) 1.01
Developmental transcriptome analysis of human erythropoiesis. Hum Mol Genet (2014) 0.99
Disruption of SF3B1 results in deregulated expression and splicing of key genes and pathways in myelodysplastic syndrome hematopoietic stem and progenitor cells. Leukemia (2014) 0.94
Translational isoforms of FOG1 regulate GATA1-interacting complexes. J Biol Chem (2009) 0.85
Histones to the cytosol: exportin 7 is essential for normal terminal erythroid nuclear maturation. Blood (2014) 0.83
Identification, characterization and expression of novel Sex Hormone Binding Globulin alternative first exons in the human prostate. BMC Mol Biol (2009) 0.81
Ferroportin and erythroid cells: an update. Adv Hematol (2010) 0.81
Coupled transcription-splicing regulation of mutually exclusive splicing events at the 5' exons of protein 4.1R gene. Blood (2009) 0.81
A tissue-specific chromatin loop activates the erythroid ankyrin-1 promoter. Blood (2012) 0.80
Molecular evolution of multiple-level control of heme biosynthesis pathway in animal kingdom. PLoS One (2014) 0.75
The transcriptional landscape of the mammalian genome. Science (2005) 37.63
An analysis of 5'-noncoding sequences from 699 vertebrate messenger RNAs. Nucleic Acids Res (1987) 36.83
Transcriptional maps of 10 human chromosomes at 5-nucleotide resolution. Science (2005) 16.82
Large-scale transcriptional activity in chromosomes 21 and 22. Science (2002) 14.01
Alternative pre-mRNA splicing: the logic of combinatorial control. Trends Biochem Sci (2000) 7.54
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Frequent alternative splicing of human genes. Genome Res (1999) 6.68
Protein diversity from alternative splicing: a challenge for bioinformatics and post-genome biology. Cell (2000) 5.16
Translational control of C/EBPalpha and C/EBPbeta isoform expression. Genes Dev (2000) 4.06
Direct isolation and identification of promoters in the human genome. Genome Res (2005) 3.68
Predicting Pol II promoter sequences using transcription factor binding sites. J Mol Biol (1995) 3.02
Control of eukaryotic protein synthesis by upstream open reading frames in the 5'-untranslated region of an mRNA. Biochem J (2002) 2.73
Iron metabolism and the IRE/IRP regulatory system: an update. Ann N Y Acad Sci (2004) 2.24
Statistical analysis of the 5' untranslated region of human mRNA using "Oligo-Capped" cDNA libraries. Genomics (2000) 2.09
Structural and compositional features of untranslated regions of eukaryotic mRNAs. Gene (1997) 1.69
Membrane attachment sites for the membrane cytoskeletal protein 4.1 of the red blood cell. Blood (1993) 1.54
Alternative splicing of human genes: more the rule than the exception? Trends Genet (1999) 1.36
An alternate promoter directs expression of a truncated, muscle-specific isoform of the human ankyrin 1 gene. J Biol Chem (1998) 1.27
Role of a short open reading frame in ribosome shunt on the cauliflower mosaic virus RNA leader. J Biol Chem (2000) 1.26
Combinatorial complexity of 5' alternative acetylcholinesterase transcripts and protein products. J Biol Chem (2004) 1.20
Regulation of RAR beta 2 mRNA expression: evidence for an inhibitory peptide encoded in the 5'-untranslated region. J Cell Biol (1996) 1.18
Analysis of oligonucleotide AUG start codon context in eukariotic mRNAs. Gene (2000) 1.17
Tissue specific expression of the retinoic acid receptor-beta 2: regulation by short open reading frames in the 5'-noncoding region. J Cell Biol (1994) 1.11
Aberrant iron accumulation and oxidized status of erythroid-specific delta-aminolevulinate synthase (ALAS2)-deficient definitive erythroblasts. Blood (2002) 1.06
Human uroporphyrinogen-III synthase: genomic organization, alternative promoters, and erythroid-specific expression. Genomics (2000) 1.06
Alternative 5' exons and differential splicing regulate expression of protein 4.1R isoforms with distinct N-termini. Blood (2003) 0.97
Sequences downstream of the erythroid promoter are required for high level expression of the human alpha-spectrin gene. J Biol Chem (2004) 0.89
Increased expression of the distal, but not of the proximal, Gata1 transcripts during differentiation of primary erythroid cells. J Cell Physiol (1999) 0.88
The structure and organization of the human erythroid anion exchanger (AE1) gene. Genomics (1994) 0.86
Shunting is a translation strategy used by plant pararetroviruses (Caulimoviridae). Micron (2001) 0.84
The cellular mechanisms of body iron homeostasis. Biol Res (2000) 0.82
Resolving the distinct stages in erythroid differentiation based on dynamic changes in membrane protein expression during erythropoiesis. Proc Natl Acad Sci U S A (2009) 3.00
Erythroblastic islands: niches for erythropoiesis. Blood (2008) 2.93
Primary role for adherent leukocytes in sickle cell vascular occlusion: a new paradigm. Proc Natl Acad Sci U S A (2002) 2.72
Hereditary spherocytosis. Lancet (2008) 2.37
A band 3-based macrocomplex of integral and peripheral proteins in the RBC membrane. Blood (2003) 2.24
The splicing regulatory element, UGCAUG, is phylogenetically and spatially conserved in introns that flank tissue-specific alternative exons. Nucleic Acids Res (2005) 2.20
Hepcidin as a therapeutic tool to limit iron overload and improve anemia in β-thalassemic mice. J Clin Invest (2010) 2.18
Protein 4.1R-dependent multiprotein complex: new insights into the structural organization of the red blood cell membrane. Proc Natl Acad Sci U S A (2008) 2.18
Hypoxia-induced acute lung injury in murine models of sickle cell disease. Am J Physiol Lung Cell Mol Physiol (2003) 2.08
Fox-2 splicing factor binds to a conserved intron motif to promote inclusion of protein 4.1R alternative exon 16. J Biol Chem (2006) 2.04
A correlation with exon expression approach to identify cis-regulatory elements for tissue-specific alternative splicing. Nucleic Acids Res (2007) 1.94
Contribution of parasite proteins to altered mechanical properties of malaria-infected red blood cells. Blood (2002) 1.93
The dendritic cell receptor Clec9A binds damaged cells via exposed actin filaments. Immunity (2012) 1.89
A transgenic mouse model demonstrates a dominant negative effect of a point mutation in the RPS19 gene associated with Diamond-Blackfan anemia. Blood (2010) 1.88
Quantitative assessment of sensing and sequestration of spherocytic erythrocytes by the human spleen. Blood (2012) 1.87
Hereditary spherocytosis and hereditary elliptocytosis: aberrant protein sorting during erythroblast enucleation. Blood (2010) 1.81
Disorders of red cell membrane. Br J Haematol (2008) 1.74
A Maurer's cleft-associated protein is essential for expression of the major malaria virulence antigen on the surface of infected red blood cells. J Cell Biol (2006) 1.73
The spectrin-based membrane skeleton stabilizes mouse megakaryocyte membrane systems and is essential for proplatelet and platelet formation. Blood (2011) 1.67
Targeted gene deletion demonstrates that the cell adhesion molecule ICAM-4 is critical for erythroblastic island formation. Blood (2006) 1.63
Cytoskeletal protein 4.1R negatively regulates T-cell activation by inhibiting the phosphorylation of LAT. Blood (2009) 1.57
Malaria and the red blood cell membrane. Semin Hematol (2004) 1.54
Identification of a functional role for lipid asymmetry in biological membranes: Phosphatidylserine-skeletal protein interactions modulate membrane stability. Proc Natl Acad Sci U S A (2002) 1.53
Modulation of erythrocyte membrane mechanical function by protein 4.1 phosphorylation. J Biol Chem (2004) 1.53
Mechanism of protein sorting during erythroblast enucleation: role of cytoskeletal connectivity. Blood (2003) 1.52
The sensing of poorly deformable red blood cells by the human spleen can be mimicked in vitro. Blood (2010) 1.52
Rbfox proteins regulate alternative mRNA splicing through evolutionarily conserved RNA bridges. Nat Struct Mol Biol (2013) 1.49
Membrane remodeling during reticulocyte maturation. Blood (2009) 1.47
Shear-response of the spectrin dimer-tetramer equilibrium in the red blood cell membrane. J Biol Chem (2002) 1.46
Malaria, erythrocytic infection, and anemia. Hematology Am Soc Hematol Educ Program (2009) 1.44
Red blood cell blood group antigens: structure and function. Semin Hematol (2004) 1.42
The ring-infected erythrocyte surface antigen (RESA) of Plasmodium falciparum stabilizes spectrin tetramers and suppresses further invasion. Blood (2007) 1.42
Adducin forms a bridge between the erythrocyte membrane and its cytoskeleton and regulates membrane cohesion. Blood (2009) 1.42
Rac GTPases regulate the morphology and deformability of the erythrocyte cytoskeleton. Blood (2006) 1.41
Structural and functional studies of interaction between Plasmodium falciparum knob-associated histidine-rich protein (KAHRP) and erythrocyte spectrin. J Biol Chem (2005) 1.41
Quantitative analysis of murine terminal erythroid differentiation in vivo: novel method to study normal and disordered erythropoiesis. Blood (2013) 1.39
Fluctuations of the red blood cell membrane: relation to mechanical properties and lack of ATP dependence. Biophys J (2008) 1.38
Erythrocyte remodeling by malaria parasites. Curr Opin Hematol (2007) 1.37
Lineage and species-specific long noncoding RNAs during erythro-megakaryocytic development. Blood (2014) 1.34
Racial differences in human platelet PAR4 reactivity reflect expression of PCTP and miR-376c. Nat Med (2013) 1.34
Targeted deletion of alpha-adducin results in absent beta- and gamma-adducin, compensated hemolytic anemia, and lethal hydrocephalus in mice. Blood (2008) 1.32
The hydration state of human red blood cells and their susceptibility to invasion by Plasmodium falciparum. Blood (2005) 1.32
Erythrocyte G protein as a novel target for malarial chemotherapy. PLoS Med (2006) 1.31
Erythrocyte G protein-coupled receptor signaling in malarial infection. Science (2003) 1.31
Conformational stabilities of the structural repeats of erythroid spectrin and their functional implications. J Biol Chem (2006) 1.29
Erythrocyte detergent-resistant membrane proteins: their characterization and selective uptake during malarial infection. Blood (2003) 1.26
Hereditary spherocytosis, elliptocytosis, and other red cell membrane disorders. Blood Rev (2013) 1.26
Alternative pre-mRNA splicing switches modulate gene expression in late erythropoiesis. Blood (2009) 1.25
Characterization of glycolytic enzyme interactions with murine erythrocyte membranes in wild-type and membrane protein knockout mice. Blood (2008) 1.23
Ribosomal protein S19 expression during erythroid differentiation. Blood (2002) 1.20
Decrease in hnRNP A/B expression during erythropoiesis mediates a pre-mRNA splicing switch. EMBO J (2002) 1.19
Cytoskeletal protein 4.1R affects repolarization and regulates calcium handling in the heart. Circ Res (2008) 1.17
Study of the effects of proteasome inhibitors on ribosomal protein S19 (RPS19) mutants, identified in patients with Diamond-Blackfan anemia. Haematologica (2008) 1.16
Rbfox-regulated alternative splicing is critical for zebrafish cardiac and skeletal muscle functions. Dev Biol (2011) 1.16
Significant biochemical, biophysical and metabolic diversity in circulating human cord blood reticulocytes. PLoS One (2013) 1.15
The contribution of endothelial cell P-selectin to the microvascular flow of mouse sickle erythrocytes in vivo. Blood (2004) 1.15
Functional characterization of spectrin-actin-binding domains in 4.1 family of proteins. Biochemistry (2002) 1.15
Nuclear substructure reorganization during late-stage erythropoiesis is selective and does not involve caspase cleavage of major nuclear substructural proteins. Blood (2005) 1.15
Identification and functional characterization of protein 4.1R and actin-binding sites in erythrocyte beta spectrin: regulation of the interactions by phosphatidylinositol-4,5-bisphosphate. Biochemistry (2005) 1.13
A dynamic alternative splicing program regulates gene expression during terminal erythropoiesis. Nucleic Acids Res (2014) 1.13
Plasmodium falciparum erythrocyte membrane protein 3 (PfEMP3) destabilizes erythrocyte membrane skeleton. J Biol Chem (2007) 1.12
Sickle red cell microrheology and sickle blood rheology. Microcirculation (2004) 1.12
Native ultrastructure of the red cell cytoskeleton by cryo-electron tomography. Biophys J (2011) 1.11
Phosphatidylserine binding sites in erythroid spectrin: location and implications for membrane stability. Biochemistry (2004) 1.10
Functional alteration of red blood cells by a megadalton protein of Plasmodium falciparum. Blood (2008) 1.09
Distinct distribution of specific members of protein 4.1 gene family in the mouse nephron. Kidney Int (2003) 1.07
Lamins regulate cell trafficking and lineage maturation of adult human hematopoietic cells. Proc Natl Acad Sci U S A (2013) 1.06
Mammalian alpha I-spectrin is a neofunctionalized polypeptide adapted to small highly deformable erythrocytes. Proc Natl Acad Sci U S A (2006) 1.06
Stomatin and sensory neuron mechanotransduction. J Neurophysiol (2007) 1.05
Mapping the domains of the cytoadherence ligand Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) that bind to the knob-associated histidine-rich protein (KAHRP). Mol Biochem Parasitol (2002) 1.05
A Golgi-associated protein 4.1B variant is required for assimilation of proteins in the membrane. J Cell Sci (2009) 1.04
Assignment of functional roles to parasite proteins in malaria-infected red blood cells by competitive flow-based adhesion assay. Br J Haematol (2002) 1.03
Tropomyosin modulates erythrocyte membrane stability. Blood (2006) 1.03
The N-terminal 11 amino acids of human erythrocyte band 3 are critical for aldolase binding and protein phosphorylation: implications for band 3 function. Blood (2005) 1.02
Interactions of Plasmodium falciparum erythrocyte membrane protein 3 with the red blood cell membrane skeleton. Biochim Biophys Acta (2007) 1.02
Comparison of mechanisms of anemia in mice with sickle cell disease and beta-thalassemia: peripheral destruction, ineffective erythropoiesis, and phospholipid scramblase-mediated phosphatidylserine exposure. Exp Hematol (2002) 1.01
Lipid rafts and malaria parasite infection of erythrocytes. Mol Membr Biol (2006) 1.01
Intrasplicing coordinates alternative first exons with alternative splicing in the protein 4.1R gene. EMBO J (2007) 1.01
Peptides based on alphaV-binding domains of erythrocyte ICAM-4 inhibit sickle red cell-endothelial interactions and vaso-occlusion in the microcirculation. Am J Physiol Cell Physiol (2006) 1.00
Protein and lipid trafficking induced in erythrocytes infected by malaria parasites. Cell Microbiol (2002) 1.00
Protein 4.1R links E-cadherin/beta-catenin complex to the cytoskeleton through its direct interaction with beta-catenin and modulates adherens junction integrity. Biochim Biophys Acta (2009) 0.99
Red cell indices in classification and treatment of anemias: from M.M. Wintrobes's original 1934 classification to the third millennium. Curr Opin Hematol (2013) 0.99
Resveratrol accelerates erythroid maturation by activation of FoxO3 and ameliorates anemia in beta-thalassemic mice. Haematologica (2013) 0.99
Erythrocyte NADPH oxidase activity modulated by Rac GTPases, PKC, and plasma cytokines contributes to oxidative stress in sickle cell disease. Blood (2013) 0.98
Erythrocyte membrane changes of chorea-acanthocytosis are the result of altered Lyn kinase activity. Blood (2011) 0.98
Alternative 5' exons and differential splicing regulate expression of protein 4.1R isoforms with distinct N-termini. Blood (2003) 0.97
Phosphatidylinositol-4,5-biphosphate (PIP2) differentially regulates the interaction of human erythrocyte protein 4.1 (4.1R) with membrane proteins. Biochemistry (2006) 0.97
Differential domain evolution and complex RNA processing in a family of paralogous EPB41 (protein 4.1) genes facilitate expression of diverse tissue-specific isoforms. Genomics (2004) 0.96
Efficient in vivo manipulation of alternative pre-mRNA splicing events using antisense morpholinos in mice. J Biol Chem (2010) 0.95
Detection of detergent-resistant membranes in asexual blood-stage parasites of Plasmodium falciparum. Mol Biochem Parasitol (2003) 0.95
Thermal stabilities of brain spectrin and the constituent repeats of subunits. Biochemistry (2006) 0.95