Published in Am J Physiol Lung Cell Mol Physiol on September 12, 2003
Hemolysis in sickle cell mice causes pulmonary hypertension due to global impairment in nitric oxide bioavailability. Blood (2007) 2.30
Extracellular hemin crisis triggers acute chest syndrome in sickle mice. J Clin Invest (2013) 1.58
Sickle cell disease increases high mobility group box 1: a novel mechanism of inflammation. Blood (2014) 1.44
Transient receptor potential vanilloid 1 mediates pain in mice with severe sickle cell disease. Blood (2011) 1.42
Cardiopulmonary complications of sickle cell disease: role of nitric oxide and hemolytic anemia. Hematology Am Soc Hematol Educ Program (2005) 1.36
Wheezing and asthma are independent risk factors for increased sickle cell disease morbidity. Br J Haematol (2012) 1.14
Genetic deletion of apolipoprotein A-I increases airway hyperresponsiveness, inflammation, and collagen deposition in the lung. J Lipid Res (2010) 1.12
Histopathology of experimentally induced asthma in a murine model of sickle cell disease. Blood (2008) 1.12
Targeting iNKT cells for the treatment of sickle cell disease. Clin Immunol (2011) 1.09
Vascular dysfunction in a murine model of severe hemolysis. Blood (2008) 1.08
Effects of experimental asthma on inflammation and lung mechanics in sickle cell mice. Am J Respir Cell Mol Biol (2011) 1.03
Targeting NADPH oxidase decreases oxidative stress in the transgenic sickle cell mouse penis. J Sex Med (2012) 1.02
Sildenafil promotes eNOS activation and inhibits NADPH oxidase in the transgenic sickle cell mouse penis. J Sex Med (2013) 0.92
C-reactive protein and interleukin-6 are decreased in transgenic sickle cell mice fed a high protein diet. J Nutr (2008) 0.90
Intravenous magnesium for pediatric sickle cell vaso-occlusive crisis: methodological issues of a randomized controlled trial. Pediatr Blood Cancer (2014) 0.90
Morphological and functional platelet abnormalities in Berkeley sickle cell mice. Blood Cells Mol Dis (2008) 0.90
Inhibition of myeloperoxidase decreases vascular oxidative stress and increases vasodilatation in sickle cell disease mice. J Lipid Res (2013) 0.86
Risk factors for increased ED utilization in a multinational cohort of children with sickle cell disease. Acad Emerg Med (2012) 0.86
Anion exchange HPLC isolation of high-density lipoprotein (HDL) and on-line estimation of proinflammatory HDL. PLoS One (2014) 0.83
Sickle cell vaso-occlusive crisis induces the release of circulating serum heat shock protein-70. Am J Hematol (2005) 0.83
Original Research: Diametric effects of hypoxia on pathophysiology of sickle cell disease in a murine model. Exp Biol Med (Maywood) (2016) 0.80
Cough and wheeze events are temporally associated with increased pain in individuals with sickle cell disease without asthma. Br J Haematol (2015) 0.79
Wheezing in children with sickle cell disease. Curr Opin Pediatr (2014) 0.77
Resolvins Decrease Oxidative Stress Mediated Macrophage and Epithelial Cell Interaction through Decreased Cytokine Secretion. PLoS One (2015) 0.77
Sickle erythrocytes and platelets augment lung leukotriene synthesis with downregulation of anti-inflammatory proteins: relevance in the pathology of the acute chest syndrome. Pulm Circ (2014) 0.76
Do we kNOw how HSP90 and eNOS mediate lung injury in sickle cell disease? Am J Physiol Lung Cell Mol Physiol (2004) 0.75
Cardiorespiratory pathogenesis of sickle cell disease in a mouse model. Sci Rep (2017) 0.75
Histone demethylation mediated by the nuclear amine oxidase homolog LSD1. Cell (2004) 21.30
Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy (2012) 20.08
Long noncoding RNA as modular scaffold of histone modification complexes. Science (2010) 15.23
ING2 PHD domain links histone H3 lysine 4 methylation to active gene repression. Nature (2006) 9.30
A DNA vector-based RNAi technology to suppress gene expression in mammalian cells. Proc Natl Acad Sci U S A (2002) 8.57
Reversal of histone lysine trimethylation by the JMJD2 family of histone demethylases. Cell (2006) 7.08
A histone H3 lysine 27 demethylase regulates animal posterior development. Nature (2007) 6.57
Coordinated histone modifications mediated by a CtBP co-repressor complex. Nature (2003) 6.48
The X-linked mental retardation gene SMCX/JARID1C defines a family of histone H3 lysine 4 demethylases. Cell (2007) 6.04
Regulation of LSD1 histone demethylase activity by its associated factors. Mol Cell (2005) 5.74
Histone methylation: a dynamic mark in health, disease and inheritance. Nat Rev Genet (2012) 5.42
New nomenclature for chromatin-modifying enzymes. Cell (2007) 5.34
Bariatric surgery for severely overweight adolescents: concerns and recommendations. Pediatrics (2004) 5.01
Genome-wide regulation of 5hmC, 5mC, and gene expression by Tet1 hydroxylase in mouse embryonic stem cells. Mol Cell (2011) 4.89
Recognition of unmethylated histone H3 lysine 4 links BHC80 to LSD1-mediated gene repression. Nature (2007) 4.49
Transgenerational epigenetic inheritance of longevity in Caenorhabditis elegans. Nature (2011) 4.41
RAG2 PHD finger couples histone H3 lysine 4 trimethylation with V(D)J recombination. Nature (2007) 4.35
Reversal of histone methylation: biochemical and molecular mechanisms of histone demethylases. Annu Rev Biochem (2010) 3.50
Comparative dietary therapy effectiveness in remission of pediatric eosinophilic esophagitis. J Allergy Clin Immunol (2012) 3.45
Structural insights into histone demethylation by JMJD2 family members. Cell (2006) 3.37
Yin Yang 1 is a negative regulator of p53. Cell (2004) 3.24
Yin Yang 1 is a critical regulator of B-cell development. Genes Dev (2007) 3.06
The Brd4 extraterminal domain confers transcription activation independent of pTEFb by recruiting multiple proteins, including NSD3. Mol Cell Biol (2011) 3.01
Resolving the distinct stages in erythroid differentiation based on dynamic changes in membrane protein expression during erythropoiesis. Proc Natl Acad Sci U S A (2009) 3.00
Erythroblastic islands: niches for erythropoiesis. Blood (2008) 2.93
Enzymatic and structural insights for substrate specificity of a family of jumonji histone lysine demethylases. Nat Struct Mol Biol (2009) 2.87
SCFbeta-TRCP controls oncogenic transformation and neural differentiation through REST degradation. Nature (2008) 2.84
Mechanisms involved in the regulation of histone lysine demethylases. Curr Opin Cell Biol (2008) 2.81
Primary role for adherent leukocytes in sickle cell vascular occlusion: a new paradigm. Proc Natl Acad Sci U S A (2002) 2.72
Identification of a Ctcf cofactor, Yy1, for the X chromosome binary switch. Mol Cell (2007) 2.69
Prolyl 4-hydroxylation regulates Argonaute 2 stability. Nature (2008) 2.51
Essential dosage-dependent functions of the transcription factor yin yang 1 in late embryonic development and cell cycle progression. Mol Cell Biol (2006) 2.48
Common variants at 5q22 associate with pediatric eosinophilic esophagitis. Nat Genet (2010) 2.47
Lid2 is required for coordinating H3K4 and H3K9 methylation of heterochromatin and euchromatin. Cell (2008) 2.42
The transcription factor Yin Yang 1 is essential for oligodendrocyte progenitor differentiation. Neuron (2007) 2.38
Hereditary spherocytosis. Lancet (2008) 2.37
Pathology of Berkeley sickle cell mice: similarities and differences with human sickle cell disease. Blood (2005) 2.37
CDK-9/cyclin T (P-TEFb) is required in two postinitiation pathways for transcription in the C. elegans embryo. Genes Dev (2002) 2.36
Mutations in CHD7, encoding a chromatin-remodeling protein, cause idiopathic hypogonadotropic hypogonadism and Kallmann syndrome. Am J Hum Genet (2008) 2.33
A band 3-based macrocomplex of integral and peripheral proteins in the RBC membrane. Blood (2003) 2.24
Histone H4K20/H3K9 demethylase PHF8 regulates zebrafish brain and craniofacial development. Nature (2010) 2.20
Hepcidin as a therapeutic tool to limit iron overload and improve anemia in β-thalassemic mice. J Clin Invest (2010) 2.18
ATRX ADD domain links an atypical histone methylation recognition mechanism to human mental-retardation syndrome. Nat Struct Mol Biol (2011) 2.18
Protein 4.1R-dependent multiprotein complex: new insights into the structural organization of the red blood cell membrane. Proc Natl Acad Sci U S A (2008) 2.18
Patrol detection for replica attacks on wireless sensor networks. Sensors (Basel) (2011) 2.14
Effects of D-4F on vasodilation and vessel wall thickness in hypercholesterolemic LDL receptor-null and LDL receptor/apolipoprotein A-I double-knockout mice on Western diet. Circ Res (2005) 2.06
Identification, epidemiology, and chronicity of pediatric esophageal eosinophilia, 1982-1999. J Allergy Clin Immunol (2010) 2.00
The ubiquitin carboxyl hydrolase BAP1 forms a ternary complex with YY1 and HCF-1 and is a critical regulator of gene expression. Mol Cell Biol (2010) 1.96
CDYL bridges REST and histone methyltransferases for gene repression and suppression of cellular transformation. Mol Cell (2008) 1.94
Contribution of parasite proteins to altered mechanical properties of malaria-infected red blood cells. Blood (2002) 1.93
Developmental roles of the histone lysine demethylases. Development (2009) 1.92
The dendritic cell receptor Clec9A binds damaged cells via exposed actin filaments. Immunity (2012) 1.89
A transgenic mouse model demonstrates a dominant negative effect of a point mutation in the RPS19 gene associated with Diamond-Blackfan anemia. Blood (2010) 1.88
Selective silencing by RNAi of a dominant allele that causes amyotrophic lateral sclerosis. Aging Cell (2003) 1.88
Quantitative assessment of sensing and sequestration of spherocytic erythrocytes by the human spleen. Blood (2012) 1.87
Coordinate interaction between IL-13 and epithelial differentiation cluster genes in eosinophilic esophagitis. J Immunol (2010) 1.85
S. pombe LSD1 homologs regulate heterochromatin propagation and euchromatic gene transcription. Mol Cell (2007) 1.84
A striking local esophageal cytokine expression profile in eosinophilic esophagitis. J Allergy Clin Immunol (2011) 1.82
Distinct passenger strand and mRNA cleavage activities of human Argonaute proteins. Nat Struct Mol Biol (2009) 1.81
Hereditary spherocytosis and hereditary elliptocytosis: aberrant protein sorting during erythroblast enucleation. Blood (2010) 1.81
YY1 functions with INO80 to activate transcription. Nat Struct Mol Biol (2007) 1.79
MicroRNA signature in patients with eosinophilic esophagitis, reversibility with glucocorticoids, and assessment as disease biomarkers. J Allergy Clin Immunol (2012) 1.79
Effects of 5-aza-2'-deoxycytidine on fetal hemoglobin levels, red cell adhesion, and hematopoietic differentiation in patients with sickle cell disease. Blood (2003) 1.76
Disorders of red cell membrane. Br J Haematol (2008) 1.74
Variants of thymic stromal lymphopoietin and its receptor associate with eosinophilic esophagitis. J Allergy Clin Immunol (2010) 1.74
Structural basis of the recognition of a methylated histone tail by JMJD2A. Proc Natl Acad Sci U S A (2007) 1.74
Phosphorylation by the beta-catenin/MAPK complex promotes 14-3-3-mediated nuclear export of TCF/POP-1 in signal-responsive cells in C. elegans. Cell (2004) 1.73
Human LSD2/KDM1b/AOF1 regulates gene transcription by modulating intragenic H3K4me2 methylation. Mol Cell (2010) 1.73
A Maurer's cleft-associated protein is essential for expression of the major malaria virulence antigen on the surface of infected red blood cells. J Cell Biol (2006) 1.73
Ineffectiveness of histone deacetylase inhibitors to induce apoptosis involves the transcriptional activation of NF-kappa B through the Akt pathway. J Biol Chem (2003) 1.73
A YY1-INO80 complex regulates genomic stability through homologous recombination-based repair. Nat Struct Mol Biol (2007) 1.68
Delayed hemolytic transfusion reaction/hyperhemolysis syndrome in children with sickle cell disease. Pediatrics (2003) 1.67
The spectrin-based membrane skeleton stabilizes mouse megakaryocyte membrane systems and is essential for proplatelet and platelet formation. Blood (2011) 1.67
Coagulation activation and inflammation in sickle cell disease-associated pulmonary hypertension. Haematologica (2008) 1.67
Relation of low vitamin D to nonvalvular persistent atrial fibrillation in Chinese patients. Ann Noninvasive Electrocardiol (2013) 1.66
Emerging roles for chromatin as a signal integration and storage platform. Nat Rev Mol Cell Biol (2013) 1.65
Translocations disrupting PHF21A in the Potocki-Shaffer-syndrome region are associated with intellectual disability and craniofacial anomalies. Am J Hum Genet (2012) 1.64
Targeted gene deletion demonstrates that the cell adhesion molecule ICAM-4 is critical for erythroblastic island formation. Blood (2006) 1.63
The histone demethylase UTX enables RB-dependent cell fate control. Genes Dev (2010) 1.62
NXP-2 association with SUMO-2 depends on lysines required for transcriptional repression. Proc Natl Acad Sci U S A (2006) 1.59
Par-4 links dopamine signaling and depression. Cell (2005) 1.58
Determination of oleanolic acid and ursolic acid contents in Ziziphora clinopodioides Lam. by HPLC method. Pharmacogn Mag (2010) 1.57
Characterization of human cardiac mitochondrial ATP-sensitive potassium channel and its regulation by phorbol ester in vitro. Am J Physiol Heart Circ Physiol (2005) 1.57
Cytoskeletal protein 4.1R negatively regulates T-cell activation by inhibiting the phosphorylation of LAT. Blood (2009) 1.57
Flexible long-range loops in the VH gene region of the Igh locus facilitate the generation of a diverse antibody repertoire. Immunity (2013) 1.56
Malaria and the red blood cell membrane. Semin Hematol (2004) 1.54
Identification of a functional role for lipid asymmetry in biological membranes: Phosphatidylserine-skeletal protein interactions modulate membrane stability. Proc Natl Acad Sci U S A (2002) 1.53
Modulation of erythrocyte membrane mechanical function by protein 4.1 phosphorylation. J Biol Chem (2004) 1.53
L-4F, an apolipoprotein A-1 mimetic, dramatically improves vasodilation in hypercholesterolemia and sickle cell disease. Circulation (2003) 1.53
Human thrombopoietin reduces myocardial infarct size, apoptosis, and stunning following ischaemia/reperfusion in rats. Cardiovasc Res (2007) 1.52
Mechanism of protein sorting during erythroblast enucleation: role of cytoskeletal connectivity. Blood (2003) 1.52
The sensing of poorly deformable red blood cells by the human spleen can be mimicked in vitro. Blood (2010) 1.52