Published in Dev Biol on February 29, 2008
The many roles of histone deacetylases in development and physiology: implications for disease and therapy. Nat Rev Genet (2009) 9.68
Eloquent silence: developmental functions of Class I histone deacetylases. Curr Opin Genet Dev (2008) 1.74
Loss of Dnmt1 catalytic activity reveals multiple roles for DNA methylation during pancreas development and regeneration. Dev Biol (2009) 1.40
Chemical modifier screen identifies HDAC inhibitors as suppressors of PKD models. Proc Natl Acad Sci U S A (2009) 1.36
New school in liver development: lessons from zebrafish. Hepatology (2009) 1.36
Histone deacetylase (HDAC) inhibition as a novel treatment for diabetes mellitus. Mol Med (2011) 1.34
The structural basis of gas-responsive transcription by the human nuclear hormone receptor REV-ERBbeta. PLoS Biol (2009) 1.31
Alcohol-induced protein hyperacetylation: mechanisms and consequences. World J Gastroenterol (2009) 1.15
Cftr controls lumen expansion and function of Kupffer's vesicle in zebrafish. Development (2013) 1.09
Organ-specific requirements for Hdac1 in liver and pancreas formation. Dev Biol (2008) 1.04
Glucose metabolism as a target of histone deacetylase inhibitors. Mol Endocrinol (2008) 1.01
Autophagy induction is a Tor- and Tp53-independent cell survival response in a zebrafish model of disrupted ribosome biogenesis. PLoS Genet (2013) 0.94
The mitochondrial import gene tomm22 is specifically required for hepatocyte survival and provides a liver regeneration model. Dis Model Mech (2010) 0.93
Minor class splicing shapes the zebrafish transcriptome during development. Proc Natl Acad Sci U S A (2014) 0.89
The epigenetic regulator Histone Deacetylase 1 promotes transcription of a core neurogenic programme in zebrafish embryos. BMC Genomics (2011) 0.87
HDAC inhibitors in kidney development and disease. Pediatr Nephrol (2012) 0.86
Histone deacetylase 1 is required for exocrine pancreatic epithelial proliferation in development and cancer. Cancer Biol Ther (2011) 0.86
Klf6/copeb is required for hepatic outgrowth in zebrafish and for hepatocyte specification in mouse ES cells. Dev Biol (2010) 0.85
Hypoxia-inducible factor 2 alpha is essential for hepatic outgrowth and functions via the regulation of leg1 transcription in the zebrafish embryo. PLoS One (2014) 0.85
Epigenetics, development, and cancer: zebrafish make their mark.. Birth Defects Res C Embryo Today (2011) 0.85
Zebrafish models of human liver development and disease. Compr Physiol (2013) 0.84
Effect of histone deacetylase inhibitors trichostatin A and valproic acid on hair cell regeneration in zebrafish lateral line neuromasts. Front Cell Neurosci (2014) 0.84
Binge ethanol-induced HDAC3 down-regulates Cpt1α expression leading to hepatic steatosis and injury. Alcohol Clin Exp Res (2013) 0.83
Hepatocyte growth factor signaling in intrapancreatic ductal cells drives pancreatic morphogenesis. PLoS Genet (2013) 0.83
Identification of estrogen target genes during zebrafish embryonic development through transcriptomic analysis. PLoS One (2013) 0.83
Augmenter of liver regeneration (alr) promotes liver outgrowth during zebrafish hepatogenesis. PLoS One (2012) 0.82
Developmental exposure to valproic acid alters the expression of microRNAs involved in neurodevelopment in zebrafish. Neurotoxicol Teratol (2013) 0.80
Islet-1 may function as an assistant factor for histone acetylation and regulation of cardiac development-related transcription factor Mef2c expression. PLoS One (2013) 0.79
Loss of cftr function leads to pancreatic destruction in larval zebrafish. Dev Biol (2015) 0.79
Adoption of the Q transcriptional regulatory system for zebrafish transgenesis. Methods (2013) 0.78
Regulation of primitive hematopoiesis by class I histone deacetylases. Dev Dyn (2013) 0.77
Growth/differentiation factor-11: an evolutionary conserved growth factor in vertebrates. Dev Genes Evol (2010) 0.76
Zebrafish as a disease model for studying human hepatocellular carcinoma. World J Gastroenterol (2015) 0.76
In Vivo Screening Using Transgenic Zebrafish Embryos Reveals New Effects of HDAC Inhibitors Trichostatin A and Valproic Acid on Organogenesis. PLoS One (2016) 0.76
The lure of zebrafish in liver research: regulation of hepatic growth in development and regeneration. Curr Opin Genet Dev (2015) 0.76
Histone deacetylase 1 is required for the development of the zebrafish inner ear. Sci Rep (2016) 0.75
Zebrafish Discoveries in Cancer Epigenetics. Adv Exp Med Biol (2016) 0.75
Selenoprotein H is an essential regulator of redox homeostasis that cooperates with p53 in development and tumorigenesis. Proc Natl Acad Sci U S A (2016) 0.75
Four and a Half LIM Domains 1b (Fhl1b) Is Essential for Regulating the Liver versus Pancreas Fate Decision and for β-Cell Regeneration. PLoS Genet (2016) 0.75
Epigenetic regulation of left-right asymmetry by DNA methylation. EMBO J (2017) 0.75
Crystal structure of an avian influenza polymerase PA(N) reveals an endonuclease active site. Nature (2009) 4.49
Crystal structure of the polymerase PA(C)-PB1(N) complex from an avian influenza H5N1 virus. Nature (2008) 3.06
Conservation of gene expression signatures between zebrafish and human liver tumors and tumor progression. Nat Biotechnol (2005) 2.51
Transcriptome analysis of zebrafish embryogenesis using microarrays. PLoS Genet (2005) 2.32
Zebrafish mRNA sequencing deciphers novelties in transcriptome dynamics during maternal to zygotic transition. Genome Res (2011) 2.29
Fgf10 regulates hepatopancreatic ductal system patterning and differentiation. Nat Genet (2007) 2.14
Toxicity of silver nanoparticles in zebrafish models. Nanotechnology (2008) 1.89
Angiomyogenesis for cardiac repair using human myoblasts as carriers of human vascular endothelial growth factor. J Mol Med (Berl) (2004) 1.65
Requirement of vasculogenesis and blood circulation in late stages of liver growth in zebrafish. BMC Dev Biol (2008) 1.62
ADAMTS5 functions as an anti-angiogenic and anti-tumorigenic protein independent of its proteoglycanase activity. Am J Pathol (2012) 1.60
Combining pharmacological mobilization with intramyocardial delivery of bone marrow cells over-expressing VEGF is more effective for cardiac repair. J Mol Cell Cardiol (2006) 1.58
The recruitment of blood coagulation factor X into snake venom gland as a toxin: the role of promoter cis-elements in its expression. Thromb Haemost (2009) 1.43
RhoA acts downstream of Wnt5 and Wnt11 to regulate convergence and extension movements by involving effectors Rho kinase and Diaphanous: use of zebrafish as an in vivo model for GTPase signaling. Cell Signal (2005) 1.35
Analyses of pancreas development by generation of gfp transgenic zebrafish using an exocrine pancreas-specific elastaseA gene promoter. Exp Cell Res (2006) 1.28
Smoking of beedies and cataract: cadmium and vitamin C in the lens and blood. Br J Ophthalmol (1995) 1.27
Development of zebrafish swimbladder: The requirement of Hedgehog signaling in specification and organization of the three tissue layers. Dev Biol (2009) 1.26
Comparative transcriptome analyses indicate molecular homology of zebrafish swimbladder and mammalian lung. PLoS One (2011) 1.25
Comparison of the toxicity of silver, gold and platinum nanoparticles in developing zebrafish embryos. Nanotoxicology (2010) 1.24
Expression analyses of zebrafish transferrin, ifabp, and elastaseB mRNAs as differentiation markers for the three major endodermal organs: liver, intestine, and exocrine pancreas. Dev Dyn (2004) 1.22
An inducible kras(V12) transgenic zebrafish model for liver tumorigenesis and chemical drug screening. Dis Model Mech (2011) 1.17
The role of autophagy in liver cancer: molecular mechanisms and potential therapeutic targets. Biochim Biophys Acta (2013) 1.17
Eales disease--an update. Surv Ophthalmol (2002) 1.15
Microdystrophin ameliorates muscular dystrophy in the canine model of duchenne muscular dystrophy. Mol Ther (2013) 1.13
A high level of liver-specific expression of oncogenic Kras(V12) drives robust liver tumorigenesis in transgenic zebrafish. Dis Model Mech (2011) 1.13
Hepatic and extrahepatic expression of vitellogenin genes in the zebrafish, Danio rerio. Gene (2005) 1.12
Expressed sequence tag analysis of expression profiles of zebrafish testis and ovary. Gene (2002) 1.11
Peptides derived from human decorin leucine-rich repeat 5 inhibit angiogenesis. J Biol Chem (2005) 1.11
Modeling liver cancer using zebrafish: a comparative oncogenomics approach. Cell Cycle (2006) 1.10
Inducible and repressable oncogene-addicted hepatocellular carcinoma in Tet-on xmrk transgenic zebrafish. J Hepatol (2011) 1.09
Plasma homocysteine and total thiol content in patients with exudative age-related macular degeneration. Eye (Lond) (2006) 1.07
Angiopoietin 1 promotes tumor angiogenesis and tumor vessel plasticity of human cervical cancer in mice. Exp Cell Res (2002) 1.07
Primary vitrectomy for combined rhegmatogenous retinal detachment and choroidal detachment with or without oral corticosteroids: a pilot study. Retina (2005) 1.07
Recapitulation of fast skeletal muscle development in zebrafish by transgenic expression of GFP under the mylz2 promoter. Dev Dyn (2003) 1.03
Mercury-induced hepatotoxicity in zebrafish: in vivo mechanistic insights from transcriptome analysis, phenotype anchoring and targeted gene expression validation. BMC Genomics (2010) 1.03
Combined activity of the two Gli2 genes of zebrafish play a major role in Hedgehog signaling during zebrafish neurodevelopment. Mol Cell Neurosci (2007) 1.02
Pharmacologically induced angiogenesis in transgenic zebrafish. Biochem Biophys Res Commun (2008) 1.01
K-ras/PI3K-Akt signaling is essential for zebrafish hematopoiesis and angiogenesis. PLoS One (2008) 1.01
Demonstration of site-directed recombination in transgenic zebrafish using the Cre/loxP system. Transgenic Res (2005) 1.01
Zebrafish whole-adult-organism chemogenomics for large-scale predictive and discovery chemical biology. PLoS Genet (2008) 1.00
A transgenic zebrafish liver tumor model with inducible Myc expression reveals conserved Myc signatures with mammalian liver tumors. Dis Model Mech (2012) 1.00
Morphological and molecular evidence for functional organization along the rostrocaudal axis of the adult zebrafish intestine. BMC Genomics (2010) 0.99
Zebrafish for drug toxicity screening: bridging the in vitro cell-based models and in vivo mammalian models. Expert Opin Drug Metab Toxicol (2011) 0.98
Transcriptomic analyses of sexual dimorphism of the zebrafish liver and the effect of sex hormones. PLoS One (2013) 0.96
Improved angiogenic response in pig heart following ischaemic injury using human skeletal myoblast simultaneously expressing VEGF165 and angiopoietin-1. Eur J Heart Fail (2006) 0.96
Comprehensive profiling of zebrafish hepatic proximal promoter CpG island methylation and its modification during chemical carcinogenesis. BMC Genomics (2011) 0.95
Antibacterial activity of the white precipitate formed on the corneal surface after treatment with ciprofloxacin ophthalmic solution. Cornea (1999) 0.95
Medaka cleavage embryos are capable of generating ES-like cell cultures. Int J Biol Sci (2011) 0.94
Transcriptome kinetics of arsenic-induced adaptive response in zebrafish liver. Physiol Genomics (2006) 0.94
Ziwi, the zebrafish homologue of the Drosophila piwi: co-localization with vasa at the embryonic genital ridge and gonad-specific expression in the adults. Mech Dev (2002) 0.93
Wnt signaling is required for early development of zebrafish swimbladder. PLoS One (2011) 0.92
Isthmin is a novel secreted angiogenesis inhibitor that inhibits tumour growth in mice. J Cell Mol Med (2011) 0.92
Platelet-derived growth factor receptor alpha (pdgfr-alpha) gene in zebrafish embryonic development. Mech Dev (2002) 0.92
Proteomic analysis of protein profiles during early development of the zebrafish, Danio rerio. Proteomics (2006) 0.90
Enhancement of bone formation by genetically-engineered bone marrow stromal cells expressing BMP-2, VEGF and angiopoietin-1. Biotechnol Lett (2009) 0.90
Biochemistry of homocysteine in health and diseases. Indian J Biochem Biophys (2006) 0.90
Dystrophin deficiency compromises force production of the extensor carpi ulnaris muscle in the canine model of Duchenne muscular dystrophy. PLoS One (2012) 0.90
Localized rbp4 expression in the yolk syncytial layer plays a role in yolk cell extension and early liver development. BMC Dev Biol (2007) 0.90
Metabolomics of developing zebrafish embryos using gas chromatography- and liquid chromatography-mass spectrometry. Mol Biosyst (2013) 0.89
Genome-wide identification of molecular pathways and biomarkers in response to arsenic exposure in zebrafish liver. PLoS One (2013) 0.89
Incorporating zebrafish omics into chemical biology and toxicology. Zebrafish (2010) 0.89
Development of estrogen-responsive transgenic medaka for environmental monitoring of endocrine disrupters. Environ Sci Technol (2005) 0.89
Development of a heat shock inducible gfp transgenic zebrafish line by using the zebrafish hsp27 promoter. Gene (2007) 0.88
Ziwi, the zebrafish homologue of the Drosophila piwi: co-localization with vasa at the embryonic genital ridge and gonad-specific expression in the adults. Gene Expr Patterns (2002) 0.88
Molecular cloning of zebrafish and medaka vitellogenin genes and comparison of their expression in response to 17beta-estradiol. Gene (2004) 0.87
Super resolution microscopy reveals that caveolin-1 is required for spatial organization of CRFB1 and subsequent antiviral signaling in zebrafish. PLoS One (2013) 0.87
Molecular evolution of vertebrate goose-type lysozyme genes. J Mol Evol (2003) 0.87
Toxicogenomic and phenotypic analyses of bisphenol-A early-life exposure toxicity in zebrafish. PLoS One (2011) 0.86
Vhnf1 acts downstream of Bmp, Fgf, and RA signals to regulate endocrine beta cell development in zebrafish. Dev Biol (2006) 0.86
The interaction of epithelial Ihha and mesenchymal Fgf10 in zebrafish esophageal and swimbladder development. Dev Biol (2011) 0.86
Zebrafish spotted-microarray for genome-wide expression profiling experiments. Part I: array printing and hybridization. Methods Mol Biol (2009) 0.86
CUL2 is required for the activity of hypoxia-inducible factor and vasculogenesis. J Biol Chem (2008) 0.86
Genomewide expression analysis in zebrafish mind bomb alleles with pancreas defects of different severity identifies putative Notch responsive genes. PLoS One (2008) 0.86
Liver tumor models in transgenic zebrafish: an alternative in vivo approach to study hepatocarcinogenes. Future Oncol (2012) 0.86
Interordinal chimera formation between medaka and zebrafish for analyzing stem cell differentiation. Stem Cells Dev (2012) 0.86
Fluorescent transgenic zebrafish Tg(nkx2.2a:mEGFP) provides a highly sensitive monitoring tool for neurotoxins. PLoS One (2013) 0.86
Maize Ac/Ds transposon system leads to highly efficient germline transmission of transgenes in medaka (Oryzias latipes). Biochimie (2011) 0.86
Generation of living color transgenic zebrafish to trace somatostatin-expressing cells and endocrine pancreas organization. Differentiation (2008) 0.85
Toxicogenomic responses of zebrafish embryos/larvae to tris(1,3-dichloro-2-propyl) phosphate (TDCPP) reveal possible molecular mechanisms of developmental toxicity. Environ Sci Technol (2013) 0.85
Molecular conservation of estrogen-response associated with cell cycle regulation, hormonal carcinogenesis and cancer in zebrafish and human cancer cell lines. BMC Med Genomics (2011) 0.84
The first but not the second thrombospondin type 1 repeat of ADAMTS5 functions as an angiogenesis inhibitor. Biochem Biophys Res Commun (2008) 0.84
Zebrafish spotted-microarray for genome-wide expression profiling experiments: data acquisition and analysis. Methods Mol Biol (2009) 0.84
Identification of proteins differentially expressed between capillary endothelial cells of hepatocellular carcinoma and normal liver in an orthotopic rat tumor model using 2-D DIGE. Proteomics (2010) 0.84
The role of vasculature and blood circulation in zebrafish swimbladder development. BMC Dev Biol (2010) 0.84
ADAMTS4 and its proteolytic fragments differentially affect melanoma growth and angiogenesis in mice. Int J Cancer (2013) 0.84
Autologous skeletal myoblasts transduced with a new adenoviral bicistronic vector for treatment of hind limb ischemia. J Vasc Surg (2004) 0.83
Tandem-repeated Zebrafish zp3 genes possess oocyte-specific promoters and are insensitive to estrogen induction. Biol Reprod (2006) 0.83
Generation of oocyte-specifically expressed cre transgenic zebrafish for female germline excision of loxP-flanked transgene. Dev Dyn (2008) 0.83
Expression of components of Wnt and Hedgehog pathways in different tissue layers during lung development in Xenopus laevis. Gene Expr Patterns (2010) 0.82
Liver X receptor agonist T0901317 induced liver perturbation in zebrafish: histological, gene set enrichment and expression analyses. Biochim Biophys Acta (2011) 0.82
Transgenic expression of walleye dermal sarcoma virus rv-cyclin gene in zebrafish and its suppressive effect on liver tumor development after carcinogen treatment. Mar Biotechnol (NY) (2010) 0.82
Augmenter of liver regeneration (alr) promotes liver outgrowth during zebrafish hepatogenesis. PLoS One (2012) 0.82
A ΔRaf1-ER-inducible oncogenic zebrafish liver cell model identifies hepatocellular carcinoma signatures. J Pathol (2011) 0.82
A novel zebrafish kelchlike gene klhl and its human ortholog KLHL display conserved expression patterns in skeletal and cardiac muscles. Gene (2004) 0.82
Reversal of myocardial injury using genetically modulated human skeletal myoblasts in a rodent cryoinjured heart model. Eur J Heart Fail (2005) 0.82