1
|
Exogenous and endogenous glycolipid antigens activate NKT cells during microbial infections.
|
Nature
|
2005
|
7.72
|
2
|
Adjuvant-enhanced antibody responses in the absence of toll-like receptor signaling.
|
Science
|
2006
|
6.47
|
3
|
The Unc93b1 mutation 3d disrupts exogenous antigen presentation and signaling via Toll-like receptors 3, 7 and 9.
|
Nat Immunol
|
2006
|
5.83
|
4
|
Natural killer T cells recognize diacylglycerol antigens from pathogenic bacteria.
|
Nat Immunol
|
2006
|
5.51
|
5
|
Genetic analysis of host resistance: Toll-like receptor signaling and immunity at large.
|
Annu Rev Immunol
|
2006
|
5.35
|
6
|
Toll-like receptors 9 and 3 as essential components of innate immune defense against mouse cytomegalovirus infection.
|
Proc Natl Acad Sci U S A
|
2004
|
4.88
|
7
|
Herpes simplex virus encephalitis in human UNC-93B deficiency.
|
Science
|
2006
|
4.26
|
8
|
The interaction between the ER membrane protein UNC93B and TLR3, 7, and 9 is crucial for TLR signaling.
|
J Cell Biol
|
2007
|
3.72
|
9
|
TLR-dependent and TLR-independent pathways of type I interferon induction in systemic autoimmunity.
|
Nat Med
|
2007
|
3.45
|
10
|
Cutting edge: Priming of NK cells by IL-18.
|
J Immunol
|
2008
|
2.08
|
11
|
Commitment to the regulatory T cell lineage requires CARMA1 in the thymus but not in the periphery.
|
PLoS Biol
|
2009
|
2.07
|
12
|
Vesicular stomatitis virus glycoprotein G activates a specific antiviral Toll-like receptor 4-dependent pathway.
|
Virology
|
2007
|
1.94
|
13
|
Efficient T cell activation via a Toll-Interleukin 1 Receptor-independent pathway.
|
Immunity
|
2006
|
1.78
|
14
|
Jinx, an MCMV susceptibility phenotype caused by disruption of Unc13d: a mouse model of type 3 familial hemophagocytic lymphohistiocytosis.
|
J Exp Med
|
2007
|
1.73
|
15
|
The MyD88-dependent, but not the MyD88-independent, pathway of TLR4 signaling is important in clearing nontypeable haemophilus influenzae from the mouse lung.
|
J Immunol
|
2005
|
1.65
|
16
|
A toll-like receptor 2-responsive lipid effector pathway protects mammals against skin infections with gram-positive bacteria.
|
Infect Immun
|
2005
|
1.55
|
17
|
Enhanced antibacterial potential in UBP43-deficient mice against Salmonella typhimurium infection by up-regulating type I IFN signaling.
|
J Immunol
|
2005
|
1.42
|
18
|
Identification of a TLR4- and TRIF-dependent activation program of dendritic cells.
|
Eur J Immunol
|
2004
|
1.39
|
19
|
NK-cell-mediated killing of target cells triggers robust antigen-specific T-cell-mediated and humoral responses.
|
Blood
|
2009
|
1.29
|
20
|
ENU-induced phenovariance in mice: inferences from 587 mutations.
|
BMC Res Notes
|
2012
|
1.28
|
21
|
Velvet, a dominant Egfr mutation that causes wavy hair and defective eyelid development in mice.
|
Genetics
|
2004
|
1.28
|
22
|
Sensitizing anthrax lethal toxin-resistant macrophages to lethal toxin-induced killing by tumor necrosis factor-alpha.
|
J Biol Chem
|
2002
|
1.26
|
23
|
STAT5 is critical to maintain effector CD8+ T cell responses.
|
J Immunol
|
2010
|
1.25
|
24
|
Analysis of the MCMV resistome by ENU mutagenesis.
|
Mamm Genome
|
2006
|
1.23
|
25
|
Loss of T cell and B cell quiescence precedes the onset of microbial flora-dependent wasting disease and intestinal inflammation in Gimap5-deficient mice.
|
J Immunol
|
2010
|
1.13
|
26
|
ENU mutagenesis in mice.
|
Methods Mol Biol
|
2008
|
1.13
|
27
|
Soluble CD36 ectodomain binds negatively charged diacylglycerol ligands and acts as a co-receptor for TLR2.
|
PLoS One
|
2009
|
1.12
|
28
|
Expansion and function of CD8+ T cells expressing Ly49 inhibitory receptors specific for MHC class I molecules.
|
J Immunol
|
2004
|
1.02
|
29
|
ATF3 is a novel regulator of mouse neutrophil migration.
|
Blood
|
2014
|
0.96
|
30
|
Cell-associated double-stranded RNA enhances antitumor activity through the production of type I IFN.
|
J Immunol
|
2006
|
0.95
|
31
|
NKG2D mediates NK cell hyperresponsiveness and influenza-induced pathologies in a mouse model of chronic obstructive pulmonary disease.
|
J Immunol
|
2012
|
0.94
|
32
|
Lps2 and signal transduction in sepsis: at the intersection of host responses to bacteria and viruses.
|
Scand J Infect Dis
|
2003
|
0.90
|
33
|
Loss of immunological tolerance in Gimap5-deficient mice is associated with loss of Foxo in CD4+ T cells.
|
J Immunol
|
2011
|
0.90
|
34
|
Nonredundant roles of TIRAP and MyD88 in airway response to endotoxin, independent of TRIF, IL-1 and IL-18 pathways.
|
Lab Invest
|
2006
|
0.88
|
35
|
PanR1, a dominant negative missense allele of the gene encoding TNF-alpha (Tnf), does not impair lymphoid development.
|
J Immunol
|
2006
|
0.88
|
36
|
Genetic analysis of innate immunity: identification and function of the TIR adapter proteins.
|
Adv Exp Med Biol
|
2005
|
0.87
|
37
|
New therapeutic targets in immune disorders: ItpkB, Orai1 and UNC93B.
|
Expert Opin Ther Targets
|
2008
|
0.87
|
38
|
C5a regulates NKT and NK cell functions in sepsis.
|
J Immunol
|
2011
|
0.87
|
39
|
Genetic analysis of innate immunity: TIR adapter proteins in innate and adaptive immune responses.
|
Microbes Infect
|
2004
|
0.86
|
40
|
Lampe1: an ENU-germline mutation causing spontaneous hepatosteatosis identified through targeted exon-enrichment and next-generation sequencing.
|
PLoS One
|
2011
|
0.85
|
41
|
Antagonism between MyD88- and TRIF-dependent signals in B7RP-1 up-regulation.
|
Eur J Immunol
|
2005
|
0.84
|
42
|
Forward genetic dissection of afferent immunity: the role of TIR adapter proteins in innate and adaptive immune responses.
|
C R Biol
|
2004
|
0.81
|
43
|
Critical role of transmethylation in TLR signaling and systemic lupus erythematosus.
|
Clin Immunol
|
2013
|
0.80
|
44
|
The aged nonhematopoietic environment impairs natural killer cell maturation and function.
|
Aging Cell
|
2015
|
0.79
|
45
|
From phenomenon to phenotype and from phenotype to gene: forward genetics and the problem of sepsis.
|
J Infect Dis
|
2003
|
0.79
|
46
|
Dissecting innate immunity by germline mutagenesis.
|
Immunology
|
2008
|
0.77
|
47
|
An ENU mutagenesis approach to dissect "self"-induced immune responses: Unraveling the genetic footprint of immunosurveillance.
|
Oncoimmunology
|
2012
|
0.77
|
48
|
Respond to "No antigen-presentation defect in Unc93b1(3d/3d) (3d) mice".
|
Nat Immunol
|
2013
|
0.75
|