Kasper Hoebe

Author PubWeight™ 90.26‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Exogenous and endogenous glycolipid antigens activate NKT cells during microbial infections. Nature 2005 7.72
2 Adjuvant-enhanced antibody responses in the absence of toll-like receptor signaling. Science 2006 6.47
3 The Unc93b1 mutation 3d disrupts exogenous antigen presentation and signaling via Toll-like receptors 3, 7 and 9. Nat Immunol 2006 5.83
4 Natural killer T cells recognize diacylglycerol antigens from pathogenic bacteria. Nat Immunol 2006 5.51
5 Genetic analysis of host resistance: Toll-like receptor signaling and immunity at large. Annu Rev Immunol 2006 5.35
6 Toll-like receptors 9 and 3 as essential components of innate immune defense against mouse cytomegalovirus infection. Proc Natl Acad Sci U S A 2004 4.88
7 Herpes simplex virus encephalitis in human UNC-93B deficiency. Science 2006 4.26
8 The interaction between the ER membrane protein UNC93B and TLR3, 7, and 9 is crucial for TLR signaling. J Cell Biol 2007 3.72
9 TLR-dependent and TLR-independent pathways of type I interferon induction in systemic autoimmunity. Nat Med 2007 3.45
10 Cutting edge: Priming of NK cells by IL-18. J Immunol 2008 2.08
11 Commitment to the regulatory T cell lineage requires CARMA1 in the thymus but not in the periphery. PLoS Biol 2009 2.07
12 Vesicular stomatitis virus glycoprotein G activates a specific antiviral Toll-like receptor 4-dependent pathway. Virology 2007 1.94
13 Efficient T cell activation via a Toll-Interleukin 1 Receptor-independent pathway. Immunity 2006 1.78
14 Jinx, an MCMV susceptibility phenotype caused by disruption of Unc13d: a mouse model of type 3 familial hemophagocytic lymphohistiocytosis. J Exp Med 2007 1.73
15 The MyD88-dependent, but not the MyD88-independent, pathway of TLR4 signaling is important in clearing nontypeable haemophilus influenzae from the mouse lung. J Immunol 2005 1.65
16 A toll-like receptor 2-responsive lipid effector pathway protects mammals against skin infections with gram-positive bacteria. Infect Immun 2005 1.55
17 Enhanced antibacterial potential in UBP43-deficient mice against Salmonella typhimurium infection by up-regulating type I IFN signaling. J Immunol 2005 1.42
18 Identification of a TLR4- and TRIF-dependent activation program of dendritic cells. Eur J Immunol 2004 1.39
19 NK-cell-mediated killing of target cells triggers robust antigen-specific T-cell-mediated and humoral responses. Blood 2009 1.29
20 ENU-induced phenovariance in mice: inferences from 587 mutations. BMC Res Notes 2012 1.28
21 Velvet, a dominant Egfr mutation that causes wavy hair and defective eyelid development in mice. Genetics 2004 1.28
22 Sensitizing anthrax lethal toxin-resistant macrophages to lethal toxin-induced killing by tumor necrosis factor-alpha. J Biol Chem 2002 1.26
23 STAT5 is critical to maintain effector CD8+ T cell responses. J Immunol 2010 1.25
24 Analysis of the MCMV resistome by ENU mutagenesis. Mamm Genome 2006 1.23
25 Loss of T cell and B cell quiescence precedes the onset of microbial flora-dependent wasting disease and intestinal inflammation in Gimap5-deficient mice. J Immunol 2010 1.13
26 ENU mutagenesis in mice. Methods Mol Biol 2008 1.13
27 Soluble CD36 ectodomain binds negatively charged diacylglycerol ligands and acts as a co-receptor for TLR2. PLoS One 2009 1.12
28 Expansion and function of CD8+ T cells expressing Ly49 inhibitory receptors specific for MHC class I molecules. J Immunol 2004 1.02
29 ATF3 is a novel regulator of mouse neutrophil migration. Blood 2014 0.96
30 Cell-associated double-stranded RNA enhances antitumor activity through the production of type I IFN. J Immunol 2006 0.95
31 NKG2D mediates NK cell hyperresponsiveness and influenza-induced pathologies in a mouse model of chronic obstructive pulmonary disease. J Immunol 2012 0.94
32 Lps2 and signal transduction in sepsis: at the intersection of host responses to bacteria and viruses. Scand J Infect Dis 2003 0.90
33 Loss of immunological tolerance in Gimap5-deficient mice is associated with loss of Foxo in CD4+ T cells. J Immunol 2011 0.90
34 Nonredundant roles of TIRAP and MyD88 in airway response to endotoxin, independent of TRIF, IL-1 and IL-18 pathways. Lab Invest 2006 0.88
35 PanR1, a dominant negative missense allele of the gene encoding TNF-alpha (Tnf), does not impair lymphoid development. J Immunol 2006 0.88
36 Genetic analysis of innate immunity: identification and function of the TIR adapter proteins. Adv Exp Med Biol 2005 0.87
37 New therapeutic targets in immune disorders: ItpkB, Orai1 and UNC93B. Expert Opin Ther Targets 2008 0.87
38 C5a regulates NKT and NK cell functions in sepsis. J Immunol 2011 0.87
39 Genetic analysis of innate immunity: TIR adapter proteins in innate and adaptive immune responses. Microbes Infect 2004 0.86
40 Lampe1: an ENU-germline mutation causing spontaneous hepatosteatosis identified through targeted exon-enrichment and next-generation sequencing. PLoS One 2011 0.85
41 Antagonism between MyD88- and TRIF-dependent signals in B7RP-1 up-regulation. Eur J Immunol 2005 0.84
42 Forward genetic dissection of afferent immunity: the role of TIR adapter proteins in innate and adaptive immune responses. C R Biol 2004 0.81
43 Critical role of transmethylation in TLR signaling and systemic lupus erythematosus. Clin Immunol 2013 0.80
44 The aged nonhematopoietic environment impairs natural killer cell maturation and function. Aging Cell 2015 0.79
45 From phenomenon to phenotype and from phenotype to gene: forward genetics and the problem of sepsis. J Infect Dis 2003 0.79
46 Dissecting innate immunity by germline mutagenesis. Immunology 2008 0.77
47 An ENU mutagenesis approach to dissect "self"-induced immune responses: Unraveling the genetic footprint of immunosurveillance. Oncoimmunology 2012 0.77
48 Respond to "No antigen-presentation defect in Unc93b1(3d/3d) (3d) mice". Nat Immunol 2013 0.75