Published in J Immunol on August 01, 2008
Innate or adaptive immunity? The example of natural killer cells. Science (2011) 8.68
Influence of the transcription factor RORgammat on the development of NKp46+ cell populations in gut and skin. Nat Immunol (2008) 4.78
The IL-1 family: regulators of immunity. Nat Rev Immunol (2010) 4.65
Cytokine-induced memory-like natural killer cells. Proc Natl Acad Sci U S A (2009) 3.74
NK cell development, homeostasis and function: parallels with CD8⁺ T cells. Nat Rev Immunol (2011) 3.38
Inflammatory monocytes activate memory CD8(+) T and innate NK lymphocytes independent of cognate antigen during microbial pathogen invasion. Immunity (2012) 3.30
Current perspectives of natural killer cell education by MHC class I molecules. Nat Rev Immunol (2010) 1.83
Latent herpesvirus infection arms NK cells. Blood (2010) 1.80
Distinct and complementary functions of MDA5 and TLR3 in poly(I:C)-mediated activation of mouse NK cells. J Exp Med (2009) 1.67
Neutrophil depletion impairs natural killer cell maturation, function, and homeostasis. J Exp Med (2012) 1.39
NK-cell-mediated killing of target cells triggers robust antigen-specific T-cell-mediated and humoral responses. Blood (2009) 1.29
Natural killer (NK) cells in antibacterial innate immunity: angels or devils? Mol Med (2012) 1.25
Intrahepatic IL-10 maintains NKG2A+Ly49- liver NK cells in a functionally hyporesponsive state. J Immunol (2010) 1.22
Critical role for interleukin-1beta (IL-1beta) during Chlamydia muridarum genital infection and bacterial replication-independent secretion of IL-1beta in mouse macrophages. Infect Immun (2009) 1.19
Genetic and antibody-mediated reprogramming of natural killer cell missing-self recognition in vivo. Proc Natl Acad Sci U S A (2009) 1.16
Regulation of mouse NK cell development and function by cytokines. Front Immunol (2013) 1.14
Glucocorticoid regulates interleukin-37 in systemic lupus erythematosus. J Clin Immunol (2012) 1.13
Delineation of regions of the Yersinia YopM protein required for interaction with the RSK1 and PRK2 host kinases and their requirement for interleukin-10 production and virulence. Infect Immun (2010) 1.12
Memory-like responses of natural killer cells. Immunol Rev (2010) 1.11
Interleukin 18 coexpression during respiratory syncytial virus infection results in enhanced disease mediated by natural killer cells. J Virol (2010) 1.09
MicroRNA-deficient NK cells exhibit decreased survival but enhanced function. J Immunol (2012) 1.05
Dendritic cell derived cytokines in human natural killer cell differentiation and activation. Front Immunol (2013) 1.03
Mechanisms of NK cell-macrophage Bacillus anthracis crosstalk: a balance between stimulation by spores and differential disruption by toxins. PLoS Pathog (2012) 0.98
Activation of naive NK cells in response to Listeria monocytogenes requires IL-18 and contact with infected dendritic cells. J Immunol (2010) 0.97
Innate immune mechanisms in vitiligo: danger from within. Curr Opin Immunol (2013) 0.97
NK cells: immune cross-talk and therapeutic implications. Immunotherapy (2011) 0.96
IκBζ augments IL-12- and IL-18-mediated IFN-γ production in human NK cells. Blood (2011) 0.96
IL-18-primed helper NK cells collaborate with dendritic cells to promote recruitment of effector CD8+ T cells to the tumor microenvironment. Cancer Res (2013) 0.95
Utilizing cytokines to function-enable human NK cells for the immunotherapy of cancer. Scientifica (Cairo) (2014) 0.94
MicroRNA regulation of natural killer cells. Front Immunol (2013) 0.94
Α-galactosylceramide analogs with weak agonist activity for human iNKT cells define new candidate anti-inflammatory agents. PLoS One (2010) 0.93
Cytomegalovirus generates long-lived antigen-specific NK cells with diminished bystander activation to heterologous infection. J Exp Med (2014) 0.92
Activation mechanisms of natural killer cells during influenza virus infection. PLoS One (2012) 0.92
The inflammasomes: molecular effectors of host resistance against bacterial, viral, parasitic, and fungal infections. Front Microbiol (2011) 0.92
Ovine CD16+/CD14- blood lymphocytes present all the major characteristics of natural killer cells. Vet Res (2009) 0.92
Inflammasomes Coordinate Pyroptosis and Natural Killer Cell Cytotoxicity to Clear Infection by a Ubiquitous Environmental Bacterium. Immunity (2015) 0.90
Auto/paracrine control of inflammatory cytokines by acetylcholine in macrophage-like U937 cells through nicotinic receptors. Int Immunopharmacol (2009) 0.89
Cutting edge: stage-specific requirement of IL-18 for antiviral NK cell expansion. J Immunol (2015) 0.88
The exonuclease domain of Lassa virus nucleoprotein is involved in antigen-presenting-cell-mediated NK cell responses. J Virol (2014) 0.88
Immunomodulatory cytokines as therapeutic agents for melanoma. Immunotherapy (2011) 0.88
T cell regulation of natural killer cells. J Exp Med (2013) 0.87
Natural killer cell regulation by microRNAs in health and disease. J Biomed Biotechnol (2012) 0.87
Disruption of Th2 immunity results in a gender-specific expansion of IL-13 producing accessory NK cells during helminth infection. J Immunol (2009) 0.86
Killer Cell Lectin-like Receptor G1 Inhibits NK Cell Function through Activation of Adenosine 5'-Monophosphate-Activated Protein Kinase. J Immunol (2016) 0.86
Inflammasomes and anti-viral immunity. J Clin Immunol (2010) 0.85
IL-18, but not IL-15, contributes to the IL-12-dependent induction of NK-cell effector functions by Leishmania infantum in vivo. Eur J Immunol (2010) 0.85
The sterile inflammation in the exacerbation of HBV-associated liver injury. Mediators Inflamm (2015) 0.83
Differential effects of stimulatory factors on natural killer cell activities of young and aged mice. J Gerontol A Biol Sci Med Sci (2012) 0.82
Metronomic cyclophosphamide schedule-dependence of innate immune cell recruitment and tumor regression in an implanted glioma model. Cancer Lett (2014) 0.81
Favorable in vitro effects of combined IL-12 and IL-18 treatment on NK cell cytotoxicity and CD25 receptor expression in metastatic melanoma patients. J Transl Med (2015) 0.80
NK cells and their ability to modulate T cells during virus infections. Crit Rev Immunol (2014) 0.80
NK cell intrinsic regulation of MIP-1α by granzyme M. Cell Death Dis (2014) 0.79
NK cell-extrinsic IL-18 signaling is required for efficient NK-cell activation by vaccinia virus. Eur J Immunol (2014) 0.79
Migration and Tissue Tropism of Innate Lymphoid Cells. Trends Immunol (2015) 0.78
Toll-like receptor 3 regulates NK cell responses to cytokines and controls experimental metastasis. Oncoimmunology (2015) 0.78
Natural Killer Cell Sensing of Infected Cells Compensates for MyD88 Deficiency but Not IFN-I Activity in Resistance to Mouse Cytomegalovirus. PLoS Pathog (2015) 0.78
Inflammasome Activity in Non-Microbial Lung Inflammation. J Environ Immunol Toxicol (2014) 0.77
Ionomycin Treatment Renders NK Cells Hyporesponsive. PLoS One (2016) 0.76
Immunoregulatory cytokine networks: 60 years of learning from murine cytomegalovirus. Med Microbiol Immunol (2015) 0.76
Early clearance of Chikungunya virus in children is associated with a strong innate immune response. Sci Rep (2016) 0.76
Regulation of Natural Killer Cell Function by STAT3. Front Immunol (2016) 0.76
Regulation of NK Cell Activation and Effector Functions by the IL-12 Family of Cytokines: The Case of IL-27. Front Immunol (2017) 0.76
Shaping of Natural Killer Cell Antitumor Activity by Ex Vivo Cultivation. Front Immunol (2017) 0.76
Regular Voluntary Exercise Potentiates Interleukin-1β and Interleukin-18 Secretion by Increasing Caspase-1 Expression in Murine Macrophages. Mediators Inflamm (2017) 0.75
Neutrophils with protumor potential could efficiently suppress tumor growth after cytokine priming and in presence of normal NK cells. Oncotarget (2014) 0.75
IL-1β/IL-6/CRP and IL-18/ferritin: Distinct Inflammatory Programs in Infections. PLoS Pathog (2016) 0.75
LRBA is Essential for Allogeneic Responses in Bone Marrow Transplantation. Sci Rep (2016) 0.75
Current perspectives on natural killer cell education and tolerance: emerging roles for inhibitory receptors. Immunotargets Ther (2015) 0.75
Identification of Mouse Cytomegalovirus Resistance Loci by ENU Mutagenesis. Viruses (2009) 0.75
Rapid vascular responses to anthrax lethal toxin in mice containing a segment of chromosome 11 from the CAST/Ei strain on a C57BL/6 genetic background. PLoS One (2012) 0.75
Immunologic Function and Molecular Insight of Recombinant Interleukin-18. PLoS One (2016) 0.75
An NK Cell Perforin Response Elicited via IL-18 Controls Mucosal Inflammation Kinetics during Salmonella Gut Infection. PLoS Pathog (2016) 0.75
IFN-γ modulates Ly-49 receptors on NK cells in IFN-γ-induced pregnancy failure. Sci Rep (2015) 0.75
Cytochrome P450 26A1 modulates natural killer cells in mouse early pregnancy. J Cell Mol Med (2016) 0.75
γδ T Cell-Mediated Immunity to Cytomegalovirus Infection. Front Immunol (2017) 0.75
Inflammasomes and Cancer: The Dynamic Role of the Inflammasome in Tumor Development. Front Immunol (2017) 0.75
Dendritic Cell-Derived IL-32α: A Novel Inhibitory Cytokine of NK Cell Function. J Immunol (2017) 0.75
The Molecular Mechanism of Natural Killer Cells Function and Its Importance in Cancer Immunotherapy. Front Immunol (2017) 0.75
Targeted disruption of the MyD88 gene results in loss of IL-1- and IL-18-mediated function. Immunity (1998) 18.12
Functions of natural killer cells. Nat Immunol (2008) 9.88
CD107a as a functional marker for the identification of natural killer cell activity. J Immunol Methods (2004) 6.89
The Unc93b1 mutation 3d disrupts exogenous antigen presentation and signaling via Toll-like receptors 3, 7 and 9. Nat Immunol (2006) 5.83
Dendritic cells prime natural killer cells by trans-presenting interleukin 15. Immunity (2007) 5.50
Defective NK cell activity and Th1 response in IL-18-deficient mice. Immunity (1998) 4.70
In vivo developmental stages in murine natural killer cell maturation. Nat Immunol (2002) 4.25
IGIF does not drive Th1 development but synergizes with IL-12 for interferon-gamma production and activates IRAK and NFkappaB. Immunity (1997) 3.60
Functional interactions between dendritic cells and NK cells during viral infection. Nat Immunol (2002) 3.20
Acquisition of murine NK cell cytotoxicity requires the translation of a pre-existing pool of granzyme B and perforin mRNAs. Immunity (2007) 2.91
Roles for common cytokine receptor gamma-chain-dependent cytokines in the generation, differentiation, and maturation of NK cell precursors and peripheral NK cells in vivo. J Immunol (2005) 2.35
Interleukin-18. Methods (1999) 2.30
Human interferon-gamma mRNA autoregulates its translation through a pseudoknot that activates the interferon-inducible protein kinase PKR. Cell (2002) 2.01
Natural killer cell trafficking in vivo requires a dedicated sphingosine 1-phosphate receptor. Nat Immunol (2007) 2.00
Details of Toll-like receptor:adapter interaction revealed by germ-line mutagenesis. Proc Natl Acad Sci U S A (2006) 1.88
IL-12-induced IFN-gamma is dependent on caspase-1 processing of the IL-18 precursor. J Clin Invest (1999) 1.64
Cutting edge: selective IL-18 requirements for induction of compartmental IFN-gamma responses during viral infection. J Immunol (2000) 1.63
Synergy of IL-12 and IL-18 for IFN-gamma gene expression: IL-12-induced STAT4 contributes to IFN-gamma promoter activation by up-regulating the binding activity of IL-18-induced activator protein 1. J Immunol (2002) 1.48
IL-1 alpha and TNF-alpha are required for IL-12-induced development of Th1 cells producing high levels of IFN-gamma in BALB/c but not C57BL/6 mice. J Immunol (1998) 1.38
Post-transcriptional control of the interferon system. Biochimie (2007) 1.28
Natural killer cell immune responses. Immunol Res (2005) 1.10
Cellular and molecular mechanisms of IFN-gamma production induced by IL-2 and IL-12 in a human NK cell line. J Leukoc Biol (1995) 1.09
Regulation of nuclear gamma interferon gene expression by interleukin 12 (IL-12) and IL-2 represents a novel form of posttranscriptional control. Mol Cell Biol (2002) 1.07
IL-1 receptor-associated kinase 4 is essential for IL-18-mediated NK and Th1 cell responses. J Immunol (2003) 1.00
Enforced expression of Bcl-2 partially restores cell numbers but not functions of TCRgammadelta intestinal intraepithelial T lymphocytes in IL-15-deficient mice. J Immunol (2007) 0.99
Functions of natural killer cells. Nat Immunol (2008) 9.88
Recognition of single-stranded RNA viruses by Toll-like receptor 7. Proc Natl Acad Sci U S A (2004) 9.00
Essential role of mda-5 in type I IFN responses to polyriboinosinic:polyribocytidylic acid and encephalomyocarditis picornavirus. Proc Natl Acad Sci U S A (2006) 8.27
Innate lymphoid cells--a proposal for uniform nomenclature. Nat Rev Immunol (2013) 7.94
Type I interferons (alpha/beta) in immunity and autoimmunity. Annu Rev Immunol (2005) 7.74
Exogenous and endogenous glycolipid antigens activate NKT cells during microbial infections. Nature (2005) 7.72
Toll-like receptor 3 mediates West Nile virus entry into the brain causing lethal encephalitis. Nat Med (2004) 7.49
Activation of the NLRP3 inflammasome in dendritic cells induces IL-1beta-dependent adaptive immunity against tumors. Nat Med (2009) 6.73
Human NK cell education by inhibitory receptors for MHC class I. Immunity (2006) 6.73
Nomenclature of monocytes and dendritic cells in blood. Blood (2010) 6.63
Adjuvant-enhanced antibody responses in the absence of toll-like receptor signaling. Science (2006) 6.47
TLR3 deficiency in patients with herpes simplex encephalitis. Science (2007) 5.86
The Unc93b1 mutation 3d disrupts exogenous antigen presentation and signaling via Toll-like receptors 3, 7 and 9. Nat Immunol (2006) 5.83
Natural killer T cells recognize diacylglycerol antigens from pathogenic bacteria. Nat Immunol (2006) 5.51
Genetic analysis of host resistance: Toll-like receptor signaling and immunity at large. Annu Rev Immunol (2006) 5.35
Toll-like receptor 3 promotes cross-priming to virus-infected cells. Nature (2005) 5.32
CD36 is a sensor of diacylglycerides. Nature (2005) 5.20
CD14 is required for MyD88-independent LPS signaling. Nat Immunol (2005) 5.20
Toll-like receptors 9 and 3 as essential components of innate immune defense against mouse cytomegalovirus infection. Proc Natl Acad Sci U S A (2004) 4.88
Influence of the transcription factor RORgammat on the development of NKp46+ cell populations in gut and skin. Nat Immunol (2008) 4.78
Intracellular toll-like receptors. Immunity (2010) 4.66
Viral infection switches non-plasmacytoid dendritic cells into high interferon producers. Nature (2003) 4.60
The intestinal microbiota modulates the anticancer immune effects of cyclophosphamide. Science (2013) 4.60
Innate and adaptive immunity cooperate flexibly to maintain host-microbiota mutualism. Science (2009) 4.45
Interleukin-17 is a negative regulator of established allergic asthma. J Exp Med (2006) 4.38
Herpes simplex virus encephalitis in human UNC-93B deficiency. Science (2006) 4.26
Upregulation of costimulatory molecules induced by lipopolysaccharide and double-stranded RNA occurs by Trif-dependent and Trif-independent pathways. Nat Immunol (2003) 4.15
Novel insights into the relationships between dendritic cell subsets in human and mouse revealed by genome-wide expression profiling. Genome Biol (2008) 3.93
The interaction between the ER membrane protein UNC93B and TLR3, 7, and 9 is crucial for TLR signaling. J Cell Biol (2007) 3.72
The serine protease TMPRSS6 is required to sense iron deficiency. Science (2008) 3.70
Identification, activation, and selective in vivo ablation of mouse NK cells via NKp46. Proc Natl Acad Sci U S A (2007) 3.60
TLR-dependent and TLR-independent pathways of type I interferon induction in systemic autoimmunity. Nat Med (2007) 3.45
Targeting natural killer cells and natural killer T cells in cancer. Nat Rev Immunol (2012) 3.43
Toll-like receptor 9 controls anti-DNA autoantibody production in murine lupus. J Exp Med (2005) 3.43
Hypersusceptibility to vesicular stomatitis virus infection in Dicer1-deficient mice is due to impaired miR24 and miR93 expression. Immunity (2007) 3.38
Maturation of mouse NK cells is a 4-stage developmental program. Blood (2009) 3.31
A common dominant TLR5 stop codon polymorphism abolishes flagellin signaling and is associated with susceptibility to legionnaires' disease. J Exp Med (2003) 3.30
The interface between innate and adaptive immunity. Nat Immunol (2004) 3.28
A novel dendritic cell subset involved in tumor immunosurveillance. Nat Med (2006) 3.21
The XC chemokine receptor 1 is a conserved selective marker of mammalian cells homologous to mouse CD8alpha+ dendritic cells. J Exp Med (2010) 3.20
The B7 family member B7-H6 is a tumor cell ligand for the activating natural killer cell receptor NKp30 in humans. J Exp Med (2009) 3.17
Natural-killer cells and dendritic cells: "l'union fait la force". Blood (2005) 3.10
Detrimental contribution of the Toll-like receptor (TLR)3 to influenza A virus-induced acute pneumonia. PLoS Pathog (2006) 3.04
Alternatively spliced NKp30 isoforms affect the prognosis of gastrointestinal stromal tumors. Nat Med (2011) 3.03
NOD2-mediated dysbiosis predisposes mice to transmissible colitis and colorectal cancer. J Clin Invest (2013) 2.96
CD4+CD25+ regulatory T cells inhibit natural killer cell functions in a transforming growth factor-beta-dependent manner. J Exp Med (2005) 2.93
Membrane-associated Hsp72 from tumor-derived exosomes mediates STAT3-dependent immunosuppressive function of mouse and human myeloid-derived suppressor cells. J Clin Invest (2010) 2.89
IL-1R1/MyD88 signaling and the inflammasome are essential in pulmonary inflammation and fibrosis in mice. J Clin Invest (2007) 2.88
Selective associations with signaling proteins determine stimulatory versus costimulatory activity of NKG2D. Nat Immunol (2002) 2.87
Selective predisposition to bacterial infections in IRAK-4-deficient children: IRAK-4-dependent TLRs are otherwise redundant in protective immunity. J Exp Med (2007) 2.85
Cigarette smoke-induced pulmonary inflammation is TLR4/MyD88 and IL-1R1/MyD88 signaling dependent. J Immunol (2008) 2.83
Recognition of hyaluronan released in sterile injury involves a unique receptor complex dependent on Toll-like receptor 4, CD44, and MD-2. J Biol Chem (2007) 2.82
Preclinical characterization of 1-7F9, a novel human anti-KIR receptor therapeutic antibody that augments natural killer-mediated killing of tumor cells. Blood (2009) 2.75
Involvement of Toll-like receptor 5 in the recognition of flagellated bacteria. Proc Natl Acad Sci U S A (2006) 2.75
IL-1 receptor-mediated signal is an essential component of MyD88-dependent innate response to Mycobacterium tuberculosis infection. J Immunol (2007) 2.73
Does Toll-like receptor 3 play a biological role in virus infections? Virology (2004) 2.73
Chemotherapy-triggered cathepsin B release in myeloid-derived suppressor cells activates the Nlrp3 inflammasome and promotes tumor growth. Nat Med (2012) 2.71
Fatal Mycobacterium tuberculosis infection despite adaptive immune response in the absence of MyD88. J Clin Invest (2004) 2.65
Alternating electric fields arrest cell proliferation in animal tumor models and human brain tumors. Proc Natl Acad Sci U S A (2007) 2.64
The trafficking of natural killer cells. Immunol Rev (2007) 2.62
Activation of invariant NKT cells by toll-like receptor 9-stimulated dendritic cells requires type I interferon and charged glycosphingolipids. Immunity (2007) 2.58
Recognition of peptide-MHC class I complexes by activating killer immunoglobulin-like receptors. Proc Natl Acad Sci U S A (2005) 2.55
Uric acid is a danger signal activating NALP3 inflammasome in lung injury inflammation and fibrosis. Am J Respir Crit Care Med (2009) 2.45
Antigen-specific transforming growth factor β-induced Treg cells, but not natural Treg cells, ameliorate autoimmune arthritis in mice by shifting the Th17/Treg cell balance from Th17 predominance to Treg cell predominance. Arthritis Rheum (2012) 2.43
Brucella control of dendritic cell maturation is dependent on the TIR-containing protein Btp1. PLoS Pathog (2008) 2.38
Distinct and nonredundant in vivo functions of TNF produced by t cells and macrophages/neutrophils: protective and deleterious effects. Immunity (2005) 2.35
Toll-like receptor 2-deficient mice succumb to Mycobacterium tuberculosis infection. Am J Pathol (2004) 2.27
Human inflammatory dendritic cells induce Th17 cell differentiation. Immunity (2013) 2.23
Origins and functional specialization of macrophages and of conventional and monocyte-derived dendritic cells in mouse skin. Immunity (2013) 2.20
Toll-like receptor 4 expression is required to control chronic Mycobacterium tuberculosis infection in mice. J Immunol (2002) 2.17
Plant and animal sensors of conserved microbial signatures. Science (2010) 2.16
NK cell responsiveness is tuned commensurate with the number of inhibitory receptors for self-MHC class I: the rheostat model. J Immunol (2009) 2.12
Germ-line and rearranged Tcrd transcription distinguish bona fide NK cells and NK-like gammadelta T cells. Eur J Immunol (2007) 2.11
TLR-independent induction of dendritic cell maturation and adaptive immunity by negative-strand RNA viruses. J Immunol (2004) 2.10
Skin-draining lymph nodes contain dermis-derived CD103(-) dendritic cells that constitutively produce retinoic acid and induce Foxp3(+) regulatory T cells. Blood (2010) 2.09
Commitment to the regulatory T cell lineage requires CARMA1 in the thymus but not in the periphery. PLoS Biol (2009) 2.07
Toll-like receptors. Curr Biol (2011) 2.06
Immunoreceptor tyrosine-based inhibition motifs: a quest in the past and future. Immunol Rev (2008) 2.05
Activation of mast cells by double-stranded RNA: evidence for activation through Toll-like receptor 3. J Allergy Clin Immunol (2004) 2.02