Published in Cell Stem Cell on January 10, 2008
Derivation and propagation of human embryonic stem cell lines from frozen embryos in an animal product-free environment. Nat Protoc (2012) 3.30
Optimal timing of inner cell mass isolation increases the efficiency of human embryonic stem cell derivation and allows generation of sibling cell lines. Cell Stem Cell (2009) 2.31
Present state and future perspectives of using pluripotent stem cells in toxicology research. Arch Toxicol (2011) 1.69
The promise of human embryonic stem cells in aging-associated diseases. Aging (Albany NY) (2011) 1.49
Innovation in the culture and derivation of pluripotent human stem cells. Curr Opin Biotechnol (2008) 1.18
Functional genomics of 5- to 8-cell stage human embryos by blastomere single-cell cDNA analysis. PLoS One (2010) 1.10
Human embryonic stem cell lines derived from single blastomeres of two 4-cell stage embryos. Hum Reprod (2009) 1.05
Human embryonic stem cells: derivation, culture, and differentiation: a review. Restor Neurol Neurosci (2010) 1.02
Parthenogenic blastocysts derived from cumulus-free in vitro matured human oocytes. PLoS One (2010) 0.98
Safety of human embryonic stem cells in patients with terminal/incurable conditions- a retrospective analysis. Ann Neurosci (2015) 0.96
Isolation and characterization of porcine amniotic fluid-derived multipotent stem cells. PLoS One (2011) 0.96
Effect of amniotic fluid stem cells and amniotic fluid cells on the wound healing process in a white rat model. Arch Plast Surg (2013) 0.95
A teratocarcinoma-like human embryonic stem cell (hESC) line and four hESC lines reveal potentially oncogenic genomic changes. PLoS One (2010) 0.95
Genomic analysis of hESC pedigrees identifies de novo mutations and enables determination of the timing and origin of mutational events. Cell Rep (2013) 0.90
Non-embryo-destructive Extraction of Pluripotent Embryonic Stem Cells: Implications for Regenerative Medicine and Reproductive Medicine. Geburtshilfe Frauenheilkd (2015) 0.90
No relationship between embryo morphology and successful derivation of human embryonic stem cell lines. PLoS One (2010) 0.89
Molecular marks for epigenetic identification of developmental and cancer stem cells. Clin Epigenetics (2010) 0.89
Human embryonic stem cells derived from embryos at different stages of development share similar transcription profiles. PLoS One (2011) 0.89
Human embryonic stem cell cultivation: historical perspective and evolution of xeno-free culture systems. Reprod Biol Endocrinol (2015) 0.89
Power-laws and the use of pluripotent stem cell lines. PLoS One (2013) 0.88
Human stem cells from single blastomeres reveal pathways of embryonic or trophoblast fate specification. Development (2015) 0.86
The different shades of mammalian pluripotent stem cells. Hum Reprod Update (2010) 0.86
In vitro differentiation and maturation of human embryonic stem cell into multipotent cells. Stem Cells Int (2011) 0.81
Investigating cellular identity and manipulating cell fate using induced pluripotent stem cells. Stem Cell Res Ther (2012) 0.80
Defining the genomic signature of totipotency and pluripotency during early human development. PLoS One (2013) 0.80
Tapping Stem Cells to Target AMD: Challenges and Prospects. J Clin Med (2015) 0.78
Human ES cells and a blastocyst from one embryo: exciting science but conflicting ethics? Cell Stem Cell (2008) 0.78
Efficient Generation of Human Embryonic Stem Cell-Derived Corneal Endothelial Cells by Directed Differentiation. PLoS One (2015) 0.77
Vitrification of isolated mice blastomeres using a closed loading device. Reprod Biol Endocrinol (2009) 0.77
Establishment of mouse embryonic stem cells from isolated blastomeres and whole embryos using three derivation methods. J Assist Reprod Genet (2010) 0.77
Strategies for fertility preservation and restoration in the male. Facts Views Vis Obgyn (2011) 0.75
Derivation of human embryonic stem cell lines from single blastomeres of low-quality embryos by direct plating. J Assist Reprod Genet (2013) 0.75
Patenting: European stem-cell ruling is misleading. Nature (2011) 0.75
Chemical enhancement in embryo development and stem cell derivation from single blastomeres. Cloning Stem Cells (2008) 0.75
Adhesive forces in embryonic stem cell cultures. Cell Adh Migr (2012) 0.75
Sourcing human embryos for embryonic stem cell lines: problems & perspectives. Indian J Med Res (2014) 0.75
Direct conversion of fibroblasts traces the way back to our first organ-the placenta. Stem Cell Investig (2016) 0.75
Patenting stem cell technologies in Europe. Cold Spring Harb Perspect Med (2014) 0.75
Generation of human induced pluripotent stem cells by direct delivery of reprogramming proteins. Cell Stem Cell (2009) 10.52
Derivation of embryonic stem-cell lines from human blastocysts. N Engl J Med (2004) 8.89
Oxygen sensitivity severely limits the replicative lifespan of murine fibroblasts. Nat Cell Biol (2003) 8.42
Embryonic stem cell trials for macular degeneration: a preliminary report. Lancet (2012) 7.70
The senescence-associated secretory phenotype: the dark side of tumor suppression. Annu Rev Pathol (2010) 7.58
Reversal of human cellular senescence: roles of the p53 and p16 pathways. EMBO J (2003) 5.61
Stromal-epithelial interactions in aging and cancer: senescent fibroblasts alter epithelial cell differentiation. J Cell Sci (2005) 3.96
Hemangioblastic derivatives from human induced pluripotent stem cells exhibit limited expansion and early senescence. Stem Cells (2010) 3.48
131I-tositumomab therapy as initial treatment for follicular lymphoma. N Engl J Med (2005) 3.38
Nuclear FAK promotes cell proliferation and survival through FERM-enhanced p53 degradation. Mol Cell (2008) 3.31
Derivation and propagation of human embryonic stem cell lines from frozen embryos in an animal product-free environment. Nat Protoc (2012) 3.30
Differential regulation of cell motility and invasion by FAK. J Cell Biol (2003) 3.15
Derivation of hESC from intact blastocysts. Curr Protoc Stem Cell Biol (2007) 3.15
Effect of karyotype on successful human embryonic stem cell derivation. Stem Cells Dev (2010) 3.12
Human embryonic stem cell lines derived from single blastomeres. Nature (2006) 3.12
Biologic properties and enucleation of red blood cells from human embryonic stem cells. Blood (2008) 3.01
Control of motile and invasive cell phenotypes by focal adhesion kinase. Biochim Biophys Acta (2004) 2.98
Trophoblast differentiation during embryo implantation and formation of the maternal-fetal interface. J Clin Invest (2004) 2.95
Association of gamma-secretase with lipid rafts in post-Golgi and endosome membranes. J Biol Chem (2004) 2.85
Endothelial progenitor cell vascular endothelial growth factor gene transfer for vascular regeneration. Circulation (2002) 2.84
Long-term safety and function of RPE from human embryonic stem cells in preclinical models of macular degeneration. Stem Cells (2009) 2.56
Trophoblast L-selectin-mediated adhesion at the maternal-fetal interface. Science (2003) 2.40
A human-like senescence-associated secretory phenotype is conserved in mouse cells dependent on physiological oxygen. PLoS One (2010) 2.38
Derivation and comparative assessment of retinal pigment epithelium from human embryonic stem cells using transcriptomics. Cloning Stem Cells (2004) 2.32
PyK2 and FAK connections to p190Rho guanine nucleotide exchange factor regulate RhoA activity, focal adhesion formation, and cell motility. J Cell Biol (2008) 2.31
Efficient differentiation of functional hepatocytes from human embryonic stem cells. Stem Cells (2008) 2.29
Human embryonic stem cells derived without feeder cells. Lancet (2005) 2.24
Protein-based human iPS cells efficiently generate functional dopamine neurons and can treat a rat model of Parkinson disease. J Clin Invest (2011) 2.23
Human embryonic stem cell-derived cells rescue visual function in dystrophic RCS rats. Cloning Stem Cells (2006) 2.23
Hydrogen production from formic acid decomposition at room temperature using a Ag-Pd core-shell nanocatalyst. Nat Nanotechnol (2011) 2.21
Hydrogen peroxide stimulates macrophages and monocytes to actively release HMGB1. J Leukoc Biol (2006) 2.17
Generation of functional hemangioblasts from human embryonic stem cells. Nat Methods (2007) 2.06
Strategy for the creation of clinical grade hESC line banks that HLA-match a target population. EMBO Mol Med (2012) 1.93
Platelet bioreactor-on-a-chip. Blood (2014) 1.87
Embryonic and extraembryonic stem cell lines derived from single mouse blastomeres. Nature (2005) 1.86
Hedgehog is required for murine yolk sac angiogenesis. Development (2002) 1.82
St John's wort induces both cytochrome P450 3A4-catalyzed sulfoxidation and 2C19-dependent hydroxylation of omeprazole. Clin Pharmacol Ther (2004) 1.79
Conversion of mechanical force into TGF-β-mediated biochemical signals. Curr Biol (2011) 1.74
Glu(332) in the Nicastrin ectodomain is essential for gamma-secretase complex maturation but not for its activity. J Biol Chem (2008) 1.65
Maternal Rnf12/RLIM is required for imprinted X-chromosome inactivation in mice. Nature (2010) 1.64
mTOR supports long-term self-renewal and suppresses mesoderm and endoderm activities of human embryonic stem cells. Proc Natl Acad Sci U S A (2009) 1.63
Maternal antibodies enhance or prevent cytomegalovirus infection in the placenta by neonatal Fc receptor-mediated transcytosis. Am J Pathol (2006) 1.59
Cost-effectiveness of the School-Based Asthma Therapy (SBAT) program. Pediatrics (2013) 1.52
Platelets generated from human embryonic stem cells are functional in vitro and in the microcirculation of living mice. Cell Res (2011) 1.48
Human cytomegalovirus interleukin-10 downregulates metalloproteinase activity and impairs endothelial cell migration and placental cytotrophoblast invasiveness in vitro. J Virol (2004) 1.43
Reprogramming of human somatic cells using human and animal oocytes. Cloning Stem Cells (2009) 1.40
Serum-free derivation of human embryonic stem cell lines on human placental fibroblast feeders. Fertil Steril (2005) 1.39
A meta-analysis of published literature on waist-to-hip ratio and risk of breast cancer. Nutr Cancer (2002) 1.38
Derive and conquer: sourcing and differentiating stem cells for therapeutic applications. Nat Rev Drug Discov (2008) 1.38
Androgen receptor remains critical for cell-cycle progression in androgen-independent CWR22 prostate cancer cells. Am J Pathol (2006) 1.33
Derivation of human embryonic stem cells from single blastomeres. Nat Protoc (2007) 1.32
v-Src SH3-enhanced interaction with focal adhesion kinase at beta 1 integrin-containing invadopodia promotes cell invasion. J Biol Chem (2002) 1.31
Longitudinal effect of intimate partner abuse on high-risk behavior among adolescents. Arch Pediatr Adolesc Med (2003) 1.31
Integrin alpha4beta1 promotes focal adhesion kinase-independent cell motility via alpha4 cytoplasmic domain-specific activation of c-Src. Mol Cell Biol (2005) 1.30
Disruption of apical-basal polarity of human embryonic stem cells enhances hematoendothelial differentiation. Stem Cells (2007) 1.30
Accelerated Abeta deposition in APPswe/PS1deltaE9 mice with hemizygous deletions of TTR (transthyretin). J Neurosci (2007) 1.29
APH-1a is the principal mammalian APH-1 isoform present in gamma-secretase complexes during embryonic development. J Neurosci (2005) 1.26
Human cytotrophoblasts acquire aneuploidies as they differentiate to an invasive phenotype. Dev Biol (2005) 1.25
AMPK activation stimulates autophagy and ameliorates muscular dystrophy in the mdx mouse diaphragm. Am J Pathol (2012) 1.24
Human cytomegalovirus transmission from the uterus to the placenta correlates with the presence of pathogenic bacteria and maternal immunity. J Virol (2003) 1.21
Transmission of human cytomegalovirus from infected uterine microvascular endothelial cells to differentiating/invasive placental cytotrophoblasts. Virology (2002) 1.19
Activation of toll-like receptors 2 or 3 and preterm delivery in the mouse. Reprod Sci (2007) 1.17
Bone morphogenetic protein 2 mediates dentin sialophosphoprotein expression and odontoblast differentiation via NF-Y signaling. J Biol Chem (2008) 1.16
Dalbavancin or oritavancin for skin infections. N Engl J Med (2014) 1.16
Viral and bacterial pathogens at the maternal-fetal interface. J Infect Dis (2004) 1.16
Focal adhesion kinase mediates cell survival via NF-kappaB and ERK signaling pathways. Am J Physiol Cell Physiol (2006) 1.15
Establishment of human trophoblast progenitor cell lines from the chorion. Stem Cells (2011) 1.15
Papillomavirus infection requires gamma secretase. J Virol (2010) 1.12
Risk factors for breast cancer associated with mammographic features in Singaporean chinese women. Cancer Epidemiol Biomarkers Prev (2004) 1.12
Improving care for urban children with asthma: design and methods of the School-Based Asthma Therapy (SBAT) trial. J Asthma (2008) 1.12
Phase I study of the effect of gastric acid pH modulators on the bioavailability of oral dasatinib in healthy subjects. J Clin Pharmacol (2009) 1.11
Mesenchymal stem cell population derived from human pluripotent stem cells displays potent immunomodulatory and therapeutic properties. Stem Cells Dev (2014) 1.10
S-palmitoylation of gamma-secretase subunits nicastrin and APH-1. J Biol Chem (2008) 1.09
An assessment of emergency medicine residents' ability to perform in a multitasking environment. Acad Med (2009) 1.08
Tobacco use in six economically disadvantaged communities in the Dominican Republic. Nicotine Tob Res (2008) 1.08
Derivation of human embryonic stem cell lines from biopsied blastomeres on human feeders with minimal exposure to xenomaterials. Stem Cells Dev (2009) 1.07