Atopic dermatitis.

IL-17 is essential for host defense against cutaneous Staphylococcus aureus infection in mice. J Clin Invest (2010) 3.40

The 'hygiene hypothesis' for autoimmune and allergic diseases: an update. Clin Exp Immunol (2010) 3.17

A homozygous frameshift mutation in the mouse Flg gene facilitates enhanced percutaneous allergen priming. Nat Genet (2009) 2.96

Filaggrin mutations that confer risk of atopic dermatitis confer greater risk for eczema herpeticum. J Allergy Clin Immunol (2009) 2.20

Recent insights into atopic dermatitis and implications for management of infectious complications. J Allergy Clin Immunol (2010) 2.20

The Malassezia genus in skin and systemic diseases. Clin Microbiol Rev (2012) 1.95

Th2 Cytokines and Atopic Dermatitis. J Clin Cell Immunol (2011) 1.91

A common variant on chromosome 11q13 is associated with atopic dermatitis. Nat Genet (2009) 1.91

Cutaneous immunosurveillance and regulation of inflammation by group 2 innate lymphoid cells. Nat Immunol (2013) 1.91

An update on the genetics of atopic dermatitis: scratching the surface in 2009. J Allergy Clin Immunol (2010) 1.73

Thymic stromal lymphopoietin overproduced by keratinocytes in mouse skin aggravates experimental asthma. Proc Natl Acad Sci U S A (2009) 1.63

Persistence of mild to moderate atopic dermatitis. JAMA Dermatol (2014) 1.63

Mast cells in atopic dermatitis. Curr Opin Immunol (2009) 1.63

Meta-analysis of genome-wide association studies identifies three new risk loci for atopic dermatitis. Nat Genet (2011) 1.60

Emerging role of Toll-like receptors in the control of pain and itch. Neurosci Bull (2012) 1.60

Genome-wide association study identifies eight new susceptibility loci for atopic dermatitis in the Japanese population. Nat Genet (2012) 1.58

Progressive activation of T(H)2/T(H)22 cytokines and selective epidermal proteins characterizes acute and chronic atopic dermatitis. J Allergy Clin Immunol (2012) 1.56

Bcl-3 acts as an innate immune modulator by controlling antimicrobial responses in keratinocytes. J Invest Dermatol (2009) 1.52

Nonlesional atopic dermatitis skin is characterized by broad terminal differentiation defects and variable immune abnormalities. J Allergy Clin Immunol (2011) 1.50

IL-4 regulates skin homeostasis and the predisposition toward allergic skin inflammation. J Immunol (2010) 1.49

Skin-specific expression of IL-33 activates group 2 innate lymphoid cells and elicits atopic dermatitis-like inflammation in mice. Proc Natl Acad Sci U S A (2013) 1.47

The aryl hydrocarbon receptor AhR links atopic dermatitis and air pollution via induction of the neurotrophic factor artemin. Nat Immunol (2016) 1.47

Effects of the Staphylococcus aureus and Staphylococcus epidermidis Secretomes Isolated from the Skin Microbiota of Atopic Children on CD4+ T Cell Activation. PLoS One (2015) 1.46

Abnormal skin barrier in the etiopathogenesis of atopic dermatitis. Curr Opin Allergy Clin Immunol (2009) 1.43

Encoding a superantigen by Staphylococcus aureus does not affect clinical characteristics of infected atopic dermatitis lesions. Br J Dermatol (2010) 1.40

Epidermal barrier dysfunction and cutaneous sensitization in atopic diseases. J Clin Invest (2012) 1.38

An ACT1 mutation selectively abolishes interleukin-17 responses in humans with chronic mucocutaneous candidiasis. Immunity (2013) 1.35

Thymic stromal lymphopoietin and allergic disease. J Allergy Clin Immunol (2012) 1.33

Dibutyl phthalate-induced thymic stromal lymphopoietin is required for Th2 contact hypersensitivity responses. J Immunol (2010) 1.32

Infected atopic dermatitis lesions contain pharmacologic amounts of lipoteichoic acid. J Allergy Clin Immunol (2009) 1.31

Raman profiles of the stratum corneum define 3 filaggrin genotype-determined atopic dermatitis endophenotypes. J Allergy Clin Immunol (2010) 1.23

Exaggerated IL-17 response to epicutaneous sensitization mediates airway inflammation in the absence of IL-4 and IL-13. J Allergy Clin Immunol (2009) 1.22

Human atopic dermatitis complicated by eczema herpeticum is associated with abnormalities in IFN-γ response. J Allergy Clin Immunol (2011) 1.19

A sensory neuron-expressed IL-31 receptor mediates T helper cell-dependent itch: Involvement of TRPV1 and TRPA1. J Allergy Clin Immunol (2013) 1.18

Human dendritic cell functional specialization in steady-state and inflammation. Front Immunol (2014) 1.16

Mast cell interleukin-2 production contributes to suppression of chronic allergic dermatitis. Immunity (2011) 1.15

Genomic insights into the atopic eczema-associated skin commensal yeast Malassezia sympodialis. MBio (2013) 1.15

The biology of thymic stromal lymphopoietin (TSLP). Adv Pharmacol (2013) 1.12

Effect of filaggrin breakdown products on growth of and protein expression by Staphylococcus aureus. J Allergy Clin Immunol (2010) 1.12

Filaggrin-2 variation is associated with more persistent atopic dermatitis in African American subjects. J Allergy Clin Immunol (2013) 1.12

Innate and adaptive immune responses against Staphylococcus aureus skin infections. Semin Immunopathol (2011) 1.12

High-density genotyping study identifies four new susceptibility loci for atopic dermatitis. Nat Genet (2013) 1.11

Comparative proteomic profiling of patients with atopic dermatitis based on history of eczema herpeticum infection and Staphylococcus aureus colonization. J Allergy Clin Immunol (2011) 1.08

Development of atopic dermatitis-like skin disease from the chronic loss of epidermal caspase-8. Proc Natl Acad Sci U S A (2010) 1.07

Global expression profiling in atopic eczema reveals reciprocal expression of inflammatory and lipid genes. PLoS One (2008) 1.06

IL-33: a novel danger signal system in atopic dermatitis. J Invest Dermatol (2012) 1.05

Exposure to food allergens through inflamed skin promotes intestinal food allergy through the thymic stromal lymphopoietin-basophil axis. J Allergy Clin Immunol (2014) 1.03

Cathelicidin LL-37: an antimicrobial peptide with a role in inflammatory skin disease. Ann Dermatol (2012) 1.03

Human mast cell degranulation and preformed TNF secretion require mitochondrial translocation to exocytosis sites: relevance to atopic dermatitis. J Allergy Clin Immunol (2011) 1.02

Multi-ancestry genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis. Nat Genet (2015) 1.02

Thymic stromal lymphopoietin (TSLP)-mediated dermal inflammation aggravates experimental asthma. Mucosal Immunol (2012) 1.02

Specific immunotherapy in atopic dermatitis. Allergy Asthma Immunol Res (2014) 1.01

Therapeutic Implications of a Barrier-based Pathogenesis of Atopic Dermatitis. Ann Dermatol (2010) 1.00

A small molecule CRTH2 antagonist inhibits FITC-induced allergic cutaneous inflammation. Int Immunol (2008) 0.98

The multiple facets of thymic stromal lymphopoietin (TSLP) during allergic inflammation and beyond. J Leukoc Biol (2012) 0.97

Emerging pathogenic links between microbiota and the gut-lung axis. Nat Rev Microbiol (2016) 0.96

Filaggrin-stratified transcriptomic analysis of pediatric skin identifies mechanistic pathways in patients with atopic dermatitis. J Allergy Clin Immunol (2014) 0.96

Hand eczema. Indian J Dermatol (2014) 0.96

The link between allergies and eosinophilic esophagitis: implications for management strategies. Expert Rev Clin Immunol (2010) 0.95

A genome-wide association study of atopic dermatitis identifies loci with overlapping effects on asthma and psoriasis. Hum Mol Genet (2013) 0.95

Nonpathogenic bacteria alleviating atopic dermatitis inflammation induce IL-10-producing dendritic cells and regulatory Tr1 cells. J Invest Dermatol (2013) 0.95

T(H)1, T(H)2, and T(H)17 cells instruct monocytes to differentiate into specialized dendritic cell subsets. Blood (2011) 0.95

Filaggrin-dependent secretion of sphingomyelinase protects against staphylococcal α-toxin-induced keratinocyte death. J Allergy Clin Immunol (2012) 0.94

Critical role for mast cell Stat5 activity in skin inflammation. Cell Rep (2014) 0.93

DNA methylation of the filaggrin gene adds to the risk of eczema associated with loss-of-function variants. J Eur Acad Dermatol Venereol (2012) 0.93

Hwangryunhaedoktang in adult patients with atopic dermatitis: a randomised, double-blind, placebo-controlled, two-centre trial--study protocol. BMC Complement Altern Med (2011) 0.93

Natural history and risk factors of atopic dermatitis in children. Allergy Asthma Immunol Res (2014) 0.93

Unraveling the Hygiene Hypothesis of helminthes and autoimmunity: origins, pathophysiology, and clinical applications. BMC Med (2015) 0.93

Comparative transcriptomic analyses of atopic dermatitis and psoriasis reveal shared neutrophilic inflammation. J Allergy Clin Immunol (2012) 0.92

Type 2 helper T-cell cytokines induce morphologic and molecular characteristics of atopic dermatitis in human skin equivalent. Am J Pathol (2011) 0.92

Immune dysregulation after cardiothoracic surgery and incidental thymectomy: maintenance of regulatory T cells despite impaired thymopoiesis. Clin Dev Immunol (2011) 0.92

Genetic and environmental risk factors for childhood eczema development and allergic sensitization in the CCAAPS cohort. J Invest Dermatol (2009) 0.92

Therapeutic implications of a barrier-based pathogenesis of atopic dermatitis. Clin Rev Allergy Immunol (2011) 0.91

Asian sand dust aggregate causes atopic dermatitis-like symptoms in Nc/Nga mice. Allergy Asthma Clin Immunol (2015) 0.91

Spontaneous atopic dermatitis is mediated by innate immunity, with the secondary lung inflammation of the atopic march requiring adaptive immunity. J Allergy Clin Immunol (2015) 0.91

Eczema in early life: genetics, the skin barrier, and lessons learned from birth cohort studies. J Pediatr (2010) 0.90

The stratum corneum comprises three layers with distinct metal-ion barrier properties. Sci Rep (2013) 0.90

Hypoxia-inducible factors regulate filaggrin expression and epidermal barrier function. J Invest Dermatol (2014) 0.89

Atopic dermatitis. Allergy Asthma Clin Immunol (2011) 0.89

Identification of novel gene signatures in patients with atopic dermatitis complicated by eczema herpeticum. J Allergy Clin Immunol (2014) 0.88

Cutting edge: identification of the thymic stromal lymphopoietin-responsive dendritic cell subset critical for initiation of type 2 contact hypersensitivity. J Immunol (2013) 0.88

Role of macrophages in the pathogenesis of atopic dermatitis. Mediators Inflamm (2013) 0.88

Autologous immunoglobulin therapy in patients with severe recalcitrant atopic dermatitis: a preliminary report. Allergy Asthma Immunol Res (2013) 0.88

Staphylococcus aureus α-toxin modulates skin host response to viral infection. J Allergy Clin Immunol (2012) 0.87

Oxidative stress induces itch via activation of transient receptor potential subtype ankyrin 1 in mice. Neurosci Bull (2012) 0.87

Th2 cytokines increase Staphylococcus aureus alpha toxin-induced keratinocyte death through the signal transducer and activator of transcription 6 (STAT6). J Invest Dermatol (2014) 0.87

Interactions between host factors and the skin microbiome. Cell Mol Life Sci (2014) 0.87

The importance of TSLP in allergic disease and its role as a potential therapeutic target. Expert Rev Clin Immunol (2014) 0.86

Application of genetic/genomic approaches to allergic disorders. J Allergy Clin Immunol (2010) 0.86

Mast cells are required for full expression of allergen/SEB-induced skin inflammation. J Invest Dermatol (2013) 0.86

Harnessing dendritic cells in inflammatory skin diseases. Semin Immunol (2011) 0.86

An integrated epigenetic and transcriptomic analysis reveals distinct tissue-specific patterns of DNA methylation associated with atopic dermatitis. J Invest Dermatol (2014) 0.86

Identification of novel immune and barrier genes in atopic dermatitis by means of laser capture microdissection. J Allergy Clin Immunol (2015) 0.85

Specificity protein 1 is pivotal in the skin's antiviral response. J Allergy Clin Immunol (2011) 0.85

Eosinophilic esophagitis. Ann Allergy Asthma Immunol (2014) 0.84

Barrier-restoring therapies in atopic dermatitis: current approaches and future perspectives. Dermatol Res Pract (2012) 0.84

7,8,4'-Trihydroxyisoflavone attenuates DNCB-induced atopic dermatitis-like symptoms in NC/Nga mice. PLoS One (2014) 0.84

Regulation of T Cell Immunity in Atopic Dermatitis by Microbes: The Yin and Yang of Cutaneous Inflammation. Front Immunol (2015) 0.84

Genetic variation in small proline rich protein 2B as a predictor for asthma among children with eczema. Ann Allergy Asthma Immunol (2012) 0.83

An important role of α-hemolysin in extracellular vesicles on the development of atopic dermatitis induced by Staphylococcus aureus. PLoS One (2014) 0.83