Rad52 sumoylation and its involvement in the efficient induction of homologous recombination.

PubWeight™: 0.95‹?› | Rank: Top 15%

🔗 View Article (PMID 18396468)

Published in DNA Repair (Amst) on April 08, 2008

Authors

Takashi Ohuchi1, Masayuki Seki, Dana Branzei, Daisuke Maeda, Ayako Ui, Hideaki Ogiwara, Shusuke Tada, Takemi Enomoto

Author Affiliations

1: Molecular Cell Biology Laboratory, Graduate School of Pharmaceutical Sciences, Tohoku University, Aoba 6-3, Aramaki, Aoba-ku, Sendai 980-8578, Japan.

Articles citing this

Homologous recombination and its regulation. Nucleic Acids Res (2012) 2.44

Mechanisms and regulation of mitotic recombination in Saccharomyces cerevisiae. Genetics (2014) 1.27

Role of Cdc48/p97 as a SUMO-targeted segregase curbing Rad51-Rad52 interaction. Nat Cell Biol (2013) 1.20

SUMO modification regulates BLM and RAD51 interaction at damaged replication forks. PLoS Biol (2009) 1.16

Molecular pathways: understanding the role of Rad52 in homologous recombination for therapeutic advancement. Clin Cancer Res (2012) 1.11

SUMO-mediated regulation of DNA damage repair and responses. Trends Biochem Sci (2015) 1.06

Sumoylation of the BLM ortholog, Sgs1, promotes telomere-telomere recombination in budding yeast. Nucleic Acids Res (2009) 0.98

Regulation of Rad51 function by phosphorylation. EMBO Rep (2011) 0.91

The ubiquitin-proteasome system in cancer, a major player in DNA repair. Part 1: post-translational regulation. J Cell Mol Med (2009) 0.90

The SUMO isopeptidase Ulp2p is required to prevent recombination-induced chromosome segregation lethality following DNA replication stress. PLoS Genet (2011) 0.84

Survival of the replication checkpoint deficient cells requires MUS81-RAD52 function. PLoS Genet (2013) 0.83

BLM SUMOylation regulates ssDNA accumulation at stalled replication forks. Front Genet (2013) 0.83

Small ubiquitin-like modifier (SUMO) isoforms and conjugation-independent function in DNA double-strand break repair pathways. J Biol Chem (2014) 0.82

Rad52 sumoylation prevents the toxicity of unproductive Rad51 filaments independently of the anti-recombinase Srs2. PLoS Genet (2013) 0.81

SUMO Wrestles with Recombination. Biomolecules (2012) 0.80

Reappearance from Obscurity: Mammalian Rad52 in Homologous Recombination. Genes (Basel) (2016) 0.80

The proteasome factor Bag101 binds to Rad22 and suppresses homologous recombination. Sci Rep (2013) 0.78

Depletion of UBC9 Causes Nuclear Defects during the Vegetative and Sexual Life Cycles in Tetrahymena thermophila. Eukaryot Cell (2015) 0.75

Genome maintenance in Saccharomyces cerevisiae: the role of SUMO and SUMO-targeted ubiquitin ligases. Nucleic Acids Res (2017) 0.75

Human RAD52 interactions with Replication Protein A and the RAD51 presynaptic complex. J Biol Chem (2017) 0.75

Articles by these authors

KIF5B-RET fusions in lung adenocarcinoma. Nat Med (2012) 4.38

Ubc9- and mms21-mediated sumoylation counteracts recombinogenic events at damaged replication forks. Cell (2006) 3.60

A synthetic lethality-based strategy to treat cancers harboring a genetic deficiency in the chromatin remodeling factor BRG1. Cancer Res (2013) 3.08

Nrf2-mediated induction of p62 controls Toll-like receptor-4-driven aggresome-like induced structure formation and autophagic degradation. Proc Natl Acad Sci U S A (2011) 2.67

RMI, a new OB-fold complex essential for Bloom syndrome protein to maintain genome stability. Genes Dev (2008) 1.97

Geminin becomes activated as an inhibitor of Cdt1/RLF-B following nuclear import. Curr Biol (2002) 1.63

The ACF1 complex is required for DNA double-strand break repair in human cells. Mol Cell (2010) 1.57

Functional relationships of FANCC to homologous recombination, translesion synthesis, and BLM. EMBO J (2004) 1.56

Structural basis for inhibition of the replication licensing factor Cdt1 by geminin. Nature (2004) 1.50

Ubc9 is essential for viability of higher eukaryotic cells. Exp Cell Res (2002) 1.49

Premature Cdk1/Cdc5/Mus81 pathway activation induces aberrant replication and deleterious crossover. EMBO J (2013) 1.45

The Saccharomyces cerevisiae Esc2 and Smc5-6 proteins promote sister chromatid junction-mediated intra-S repair. Mol Biol Cell (2009) 1.44

Functional relation among RecQ family helicases RecQL1, RecQL5, and BLM in cell growth and sister chromatid exchange formation. Mol Cell Biol (2003) 1.43

Bloom helicase and DNA topoisomerase IIIalpha are involved in the dissolution of sister chromatids. Mol Cell Biol (2006) 1.41

A catalog of genes homozygously deleted in human lung cancer and the candidacy of PTPRD as a tumor suppressor gene. Genes Chromosomes Cancer (2010) 1.33

Interplay between the Smc5/6 complex and the Mph1 helicase in recombinational repair. Proc Natl Acad Sci U S A (2009) 1.31

Sgs1 function in the repair of DNA replication intermediates is separable from its role in homologous recombinational repair. EMBO J (2009) 1.29

Noncanonical role of the 9-1-1 clamp in the error-free DNA damage tolerance pathway. Mol Cell (2012) 1.27

SMC6 is required for MMS-induced interchromosomal and sister chromatid recombinations in Saccharomyces cerevisiae. DNA Repair (Amst) (2004) 1.26

The Smc5/6 complex and Esc2 influence multiple replication-associated recombination processes in Saccharomyces cerevisiae. Mol Biol Cell (2010) 1.22

BLM is an early responder to DNA double-strand breaks. Biochem Biophys Res Commun (2006) 1.21

Replication and recombination factors contributing to recombination-dependent bypass of DNA lesions by template switch. PLoS Genet (2010) 1.19

RecQL5 promotes genome stabilization through two parallel mechanisms--interacting with RNA polymerase II and acting as a helicase. Mol Cell Biol (2010) 1.17

The ability of Sgs1 to interact with DNA topoisomerase III is essential for damage-induced recombination. DNA Repair (Amst) (2005) 1.14

Locus-specific requirements for Spt5 in transcriptional activation and repression in Drosophila. Curr Biol (2004) 1.08

Possible involvement of RecQL4 in the repair of double-strand DNA breaks in Xenopus egg extracts. Biochim Biophys Acta (2007) 1.04

Human Werner helicase interacting protein 1 (WRNIP1) functions as a novel modulator for DNA polymerase delta. Genes Cells (2005) 1.04

Licensing for DNA replication requires a strict sequential assembly of Cdc6 and Cdt1 onto chromatin in Xenopus egg extracts. Nucleic Acids Res (2005) 1.03

Functional and physical interaction between Sgs1 and Top3 and Sgs1-independent function of Top3 in DNA recombination repair. Genes Genet Syst (2002) 1.03

Identification of RecQL1 as a Holliday junction processing enzyme in human cell lines. Nucleic Acids Res (2005) 1.01

DNA bending facilitates the error-free DNA damage tolerance pathway and upholds genome integrity. EMBO J (2014) 1.00

The histone chaperone facilitates chromatin transcription (FACT) protein maintains normal replication fork rates. J Biol Chem (2011) 0.99

SWI/SNF factors required for cellular resistance to DNA damage include ARID1A and ARID1B and show interdependent protein stability. Cancer Res (2014) 0.99

Ubc9 is required for damage-tolerance and damage-induced interchromosomal homologous recombination in S. cerevisiae. DNA Repair (Amst) (2004) 0.98

Caenorhabditis elegans geminin homologue participates in cell cycle regulation and germ line development. J Biol Chem (2005) 0.98

The INO80 chromatin remodeling complex functions in sister chromatid cohesion. Cell Cycle (2007) 0.98

In vivo kinematics of mobile-bearing knee arthroplasty in deep knee bending motion. J Orthop Res (2004) 0.97

Role of Elg1 protein in double strand break repair. Nucleic Acids Res (2006) 0.97

Budding yeast mms4 is epistatic with rad52 and the function of Mms4 can be replaced by a bacterial Holliday junction resolvase. DNA Repair (Amst) (2003) 0.97

RecQ family helicases in genome stability: lessons from gene disruption studies in DT40 cells. Cell Cycle (2008) 0.97

During replication stress, non-SMC element 5 (NSE5) is required for Smc5/6 protein complex functionality at stalled forks. J Biol Chem (2012) 0.96

Physical and functional interaction between WRNIP1 and RAD18. Genes Genet Syst (2009) 0.95

The N-terminal region of RECQL4 lacking the helicase domain is both essential and sufficient for the viability of vertebrate cells. Role of the N-terminal region of RECQL4 in cells. Biochim Biophys Acta (2011) 0.95

Rad5-dependent DNA repair functions of the Saccharomyces cerevisiae FANCM protein homolog Mph1. J Biol Chem (2012) 0.95

Analysis and results of dissociation of the polyethylene liner in the Harris-Galante I acetabular component. J Arthroplasty (2007) 0.94

Evaluation of the gamma-H2AX assay for radiation biodosimetry in a swine model. Int J Mol Sci (2013) 0.94

The SUMO pathway is required for selective degradation of DNA topoisomerase IIbeta induced by a catalytic inhibitor ICRF-193(1). FEBS Lett (2003) 0.93

The INO80 complex is required for damage-induced recombination. Biochem Biophys Res Commun (2007) 0.92

KU70/80, DNA-PKcs, and Artemis are essential for the rapid induction of apoptosis after massive DSB formation. Cell Signal (2008) 0.91

The Smc5-Smc6 complex regulates recombination at centromeric regions and affects kinetochore protein sumoylation during normal growth. PLoS One (2012) 0.90

Dpb11, the budding yeast homolog of TopBP1, functions with the checkpoint clamp in recombination repair. Nucleic Acids Res (2006) 0.90

Focus-formation of replication protein A, activation of checkpoint system and DNA repair synthesis induced by DNA double-strand breaks in Xenopus egg extract. J Cell Sci (2002) 0.90