Published in EMBO J on March 26, 2013
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Essential Roles of the Smc5/6 Complex in Replication through Natural Pausing Sites and Endogenous DNA Damage Tolerance. Mol Cell (2015) 1.62
Replication intermediates that escape Dna2 activity are processed by Holliday junction resolvase Yen1. Nat Commun (2016) 1.41
Mechanisms and regulation of mitotic recombination in Saccharomyces cerevisiae. Genetics (2014) 1.27
RNF4 and PLK1 are required for replication fork collapse in ATR-deficient cells. Genes Dev (2013) 1.17
TopBP1/Dpb11 binds DNA anaphase bridges to prevent genome instability. J Cell Biol (2013) 1.16
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SUMO-mediated regulation of DNA damage repair and responses. Trends Biochem Sci (2015) 1.06
Dual control of Yen1 nuclease activity and cellular localization by Cdk and Cdc14 prevents genome instability. Mol Cell (2014) 1.05
Visualization of recombination-mediated damage bypass by template switching. Nat Struct Mol Biol (2014) 1.05
Error-free DNA damage tolerance and sister chromatid proximity during DNA replication rely on the Polα/Primase/Ctf4 Complex. Mol Cell (2015) 1.03
A cell cycle-regulated Slx4-Dpb11 complex promotes the resolution of DNA repair intermediates linked to stalled replication. Genes Dev (2014) 1.01
DNA bending facilitates the error-free DNA damage tolerance pathway and upholds genome integrity. EMBO J (2014) 1.00
Resolving branched DNA intermediates with structure-specific nucleases during replication in eukaryotes. Chromosoma (2013) 0.95
Local regulation of the Srs2 helicase by the SUMO-like domain protein Esc2 promotes recombination at sites of stalled replication. Genes Dev (2015) 0.95
Spatial control of the GEN1 Holliday junction resolvase ensures genome stability. Nat Commun (2014) 0.94
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MUS81-EME2 promotes replication fork restart. Cell Rep (2014) 0.93
Temporal regulation of the Mus81-Mms4 endonuclease ensures cell survival under conditions of DNA damage. Nucleic Acids Res (2013) 0.91
DNA structure-specific priming of ATR activation by DNA-PKcs. J Cell Biol (2013) 0.91
Mph1 and Mus81-Mms4 prevent aberrant processing of mitotic recombination intermediates. Mol Cell (2013) 0.91
Dampening DNA damage checkpoint signalling via coordinated BRCT domain interactions. EMBO J (2015) 0.90
TopBP1 is required at mitosis to reduce transmission of DNA damage to G1 daughter cells. J Cell Biol (2015) 0.88
Reduced kinase activity of polo kinase Cdc5 affects chromosome stability and DNA damage response in S. cerevisiae. Cell Cycle (2016) 0.88
DNA damage repair machinery and HIV escape from innate immune sensing. Front Microbiol (2014) 0.87
Length-dependent processing of telomeres in the absence of telomerase. Nucleic Acids Res (2014) 0.83
Substrate specificity of the MUS81-EME2 structure selective endonuclease. Nucleic Acids Res (2013) 0.83
Control of structure-specific endonucleases to maintain genome stability. Nat Rev Mol Cell Biol (2017) 0.81
Sumoylation of the Rad1 nuclease promotes DNA repair and regulates its DNA association. Nucleic Acids Res (2014) 0.81
Srs2 promotes Mus81-Mms4-mediated resolution of recombination intermediates. Nucleic Acids Res (2015) 0.81
The Mus81-Mms4 structure-selective endonuclease requires nicked DNA junctions to undergo conformational changes and bend its DNA substrates for cleavage. Nucleic Acids Res (2014) 0.81
Cdc14 targets the Holliday junction resolvase Yen1 to the nucleus in early anaphase. Cell Cycle (2014) 0.80
Termination of Replication Stress Signaling via Concerted Action of the Slx4 Scaffold and the PP4 Phosphatase. Genetics (2015) 0.79
Resolution by unassisted Top3 points to template switch recombination intermediates during DNA replication. J Biol Chem (2013) 0.78
GEN1 promotes Holliday junction resolution by a coordinated nick and counter-nick mechanism. Nucleic Acids Res (2015) 0.78
A physiological significance of the functional interaction between Mus81 and Rad27 in homologous recombination repair. Nucleic Acids Res (2015) 0.78
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Resolution of single and double Holliday junction recombination intermediates by GEN1. Proc Natl Acad Sci U S A (2017) 0.78
Smc5/6 Mediated Sumoylation of the Sgs1-Top3-Rmi1 Complex Promotes Removal of Recombination Intermediates. Cell Rep (2016) 0.77
Enrichment of Cdk1-cyclins at DNA double-strand breaks stimulates Fun30 phosphorylation and DNA end resection. Nucleic Acids Res (2016) 0.77
G2/M chromosome transactions essentially relying on Smc5/6. Cell Cycle (2015) 0.76
Hold your horSSEs: controlling structure-selective endonucleases MUS81 and Yen1/GEN1. Front Genet (2015) 0.76
Dbf4-dependent kinase and the Rtt107 scaffold promote Mus81-Mms4 resolvase activation during mitosis. EMBO J (2017) 0.76
Multi-BRCT scaffolds use distinct strategies to support genome maintenance. Cell Cycle (2016) 0.76
The Intra-S Checkpoint Responses to DNA Damage. Genes (Basel) (2017) 0.76
The Budding Yeast Ubiquitin Protease Ubp7 Is a Novel Component Involved in S Phase Progression. J Biol Chem (2016) 0.75
Slx4 scaffolding in homologous recombination and checkpoint control: lessons from yeast. Chromosoma (2016) 0.75
Replication-Associated Recombinational Repair: Lessons from Budding Yeast. Genes (Basel) (2016) 0.75
Nucleolytic processing of aberrant replication intermediates by an Exo1-Dna2-Sae2 axis counteracts fork collapse-driven chromosome instability. Nucleic Acids Res (2016) 0.75
Esc2 promotes Mus81 complex-activity via its SUMO-like and DNA binding domains. Nucleic Acids Res (2016) 0.75
DNA Damage Tolerance Pathway Choice Through Uls1 Modulation of Srs2 SUMOylation in Saccharomyces cerevisiae. Genetics (2017) 0.75
Roles of CDK and DDK in Genome Duplication and Maintenance: Meiotic Singularities. Genes (Basel) (2017) 0.75
Role of PCNA and RFC in promoting Mus81-complex activity. BMC Biol (2017) 0.75
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The Bloom's syndrome helicase suppresses crossing over during homologous recombination. Nature (2003) 8.68
ATM- and cell cycle-dependent regulation of ATR in response to DNA double-strand breaks. Nat Cell Biol (2005) 8.27
Targets of the cyclin-dependent kinase Cdk1. Nature (2003) 8.05
Proteomic screen finds pSer/pThr-binding domain localizing Plk1 to mitotic substrates. Science (2003) 6.97
DNA end resection, homologous recombination and DNA damage checkpoint activation require CDK1. Nature (2004) 6.94
Regulation of DNA replication fork progression through damaged DNA by the Mec1/Rad53 checkpoint. Nature (2001) 6.55
A checkpoint regulates the rate of progression through S phase in S. cerevisiae in response to DNA damage. Cell (1995) 6.00
DNA damage checkpoints: from initiation to recovery or adaptation. Curr Opin Cell Biol (2007) 5.78
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Srs2 and Sgs1-Top3 suppress crossovers during double-strand break repair in yeast. Cell (2003) 5.45
Mitotic homologous recombination maintains genomic stability and suppresses tumorigenesis. Nat Rev Mol Cell Biol (2010) 5.35
Regulation of DNA repair throughout the cell cycle. Nat Rev Mol Cell Biol (2008) 5.10
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Control of the DNA damage checkpoint by chk1 and rad53 protein kinases through distinct mechanisms. Science (1999) 4.61
An auxin-based degron system for the rapid depletion of proteins in nonplant cells. Nat Methods (2009) 4.46
Multiple mechanisms control chromosome integrity after replication fork uncoupling and restart at irreparable UV lesions. Mol Cell (2006) 4.44
Functional overlap between Sgs1-Top3 and the Mms4-Mus81 endonuclease. Genes Dev (2001) 3.99
The CDK regulates repair of double-strand breaks by homologous recombination during the cell cycle. EMBO J (2004) 3.87
Regulation of Saccharomyces Rad53 checkpoint kinase during adaptation from DNA damage-induced G2/M arrest. Mol Cell (2001) 3.74
Alternate pathways involving Sgs1/Top3, Mus81/ Mms4, and Srs2 prevent formation of toxic recombination intermediates from single-stranded gaps created by DNA replication. Proc Natl Acad Sci U S A (2002) 3.70
Ubc9- and mms21-mediated sumoylation counteracts recombinogenic events at damaged replication forks. Cell (2006) 3.60
Proteome-wide identification of in vivo targets of DNA damage checkpoint kinases. Proc Natl Acad Sci U S A (2007) 3.44
The structure-specific endonuclease Mus81 contributes to replication restart by generating double-strand DNA breaks. Nat Struct Mol Biol (2007) 3.38
Identification of Holliday junction resolvases from humans and yeast. Nature (2008) 3.33
Rad51-dependent DNA structures accumulate at damaged replication forks in sgs1 mutants defective in the yeast ortholog of BLM RecQ helicase. Genes Dev (2005) 2.91
Mus81 and Yen1 promote reciprocal exchange during mitotic recombination to maintain genome integrity in budding yeast. Mol Cell (2010) 2.49
The RAD6 DNA damage tolerance pathway operates uncoupled from the replication fork and is functional beyond S phase. Cell (2010) 2.46
Cdc2-cyclin B kinase activity links Crb2 and Rqh1-topoisomerase III. Genes Dev (2002) 2.37
SUMOylation regulates Rad18-mediated template switch. Nature (2008) 2.14
Regulatory control of the resolution of DNA recombination intermediates during meiosis and mitosis. Cell (2011) 2.08
Ubiquitin-dependent DNA damage bypass is separable from genome replication. Nature (2010) 2.01
Aberrant chromosome morphology in human cells defective for Holliday junction resolution. Nature (2011) 1.97
Branch migrating sister chromatid junctions form at replication origins through Rad51/Rad52-independent mechanisms. Mol Cell (2003) 1.83
Processing of joint molecule intermediates by structure-selective endonucleases during homologous recombination in eukaryotes. Chromosoma (2011) 1.78
Exploring the roles of Mus81-Eme1/Mms4 at perturbed replication forks. DNA Repair (Amst) (2007) 1.76
Mrc1 and Srs2 are major actors in the regulation of spontaneous crossover. EMBO J (2006) 1.65
Replication checkpoint kinase Cds1 regulates Mus81 to preserve genome integrity during replication stress. Genes Dev (2005) 1.60
Temporal separation of replication and recombination requires the intra-S checkpoint. J Cell Biol (2005) 1.54
Nearby inverted repeats fuse to generate acentric and dicentric palindromic chromosomes by a replication template exchange mechanism. Genes Dev (2009) 1.50
A proteome-wide analysis of kinase-substrate network in the DNA damage response. J Biol Chem (2010) 1.46
The Saccharomyces cerevisiae Esc2 and Smc5-6 proteins promote sister chromatid junction-mediated intra-S repair. Mol Biol Cell (2009) 1.44
A coupled chemical-genetic and bioinformatic approach to Polo-like kinase pathway exploration. Chem Biol (2007) 1.42
Cell cycle-dependent regulation of the nuclease activity of Mus81-Eme1/Mms4. Nucleic Acids Res (2012) 1.40
Sgs1 function in the repair of DNA replication intermediates is separable from its role in homologous recombinational repair. EMBO J (2009) 1.29
Cleavage of stalled forks by fission yeast Mus81/Eme1 in absence of DNA replication checkpoint. Mol Biol Cell (2007) 1.28
Noncanonical role of the 9-1-1 clamp in the error-free DNA damage tolerance pathway. Mol Cell (2012) 1.27
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Fusion of nearby inverted repeats by a replication-based mechanism leads to formation of dicentric and acentric chromosomes that cause genome instability in budding yeast. Genes Dev (2009) 1.25
Behind the wheel and under the hood: functions of cyclin-dependent kinases in response to DNA damage. DNA Repair (Amst) (2009) 1.23
The Polo-box domain: a molecular integrator of mitotic kinase cascades and Polo-like kinase function. Cell Cycle (2004) 1.23
Rad52 recruitment is DNA replication independent and regulated by Cdc28 and the Mec1 kinase. EMBO J (2009) 1.20
Multiple Rad5 activities mediate sister chromatid recombination to bypass DNA damage at stalled replication forks. Mol Cell (2010) 1.20
Replication and recombination factors contributing to recombination-dependent bypass of DNA lesions by template switch. PLoS Genet (2010) 1.19
Distinct roles of Mus81, Yen1, Slx1-Slx4, and Rad1 nucleases in the repair of replication-born double-strand breaks by sister chromatid exchange. Mol Cell Biol (2012) 1.15
Pathways for Holliday junction processing during homologous recombination in Saccharomyces cerevisiae. Mol Cell Biol (2011) 1.09
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Genetic and functional interactions between Mus81-Mms4 and Rad27. Nucleic Acids Res (2010) 0.92
The replication fork's five degrees of freedom, their failure and genome rearrangements. Curr Opin Cell Biol (2009) 0.89
Requirement of replication checkpoint protein kinases Mec1/Rad53 for postreplication repair in yeast. MBio (2011) 0.83
The Saccharomyces cerevisiae Esc2 and Smc5-6 proteins promote sister chromatid junction-mediated intra-S repair. Mol Biol Cell (2009) 1.44
Interplay between the Smc5/6 complex and the Mph1 helicase in recombinational repair. Proc Natl Acad Sci U S A (2009) 1.31
Sgs1 function in the repair of DNA replication intermediates is separable from its role in homologous recombinational repair. EMBO J (2009) 1.29
Noncanonical role of the 9-1-1 clamp in the error-free DNA damage tolerance pathway. Mol Cell (2012) 1.27
The Smc5/6 complex and Esc2 influence multiple replication-associated recombination processes in Saccharomyces cerevisiae. Mol Biol Cell (2010) 1.22
Replication and recombination factors contributing to recombination-dependent bypass of DNA lesions by template switch. PLoS Genet (2010) 1.19
DNA bending facilitates the error-free DNA damage tolerance pathway and upholds genome integrity. EMBO J (2014) 1.00
Ubc9 is required for damage-tolerance and damage-induced interchromosomal homologous recombination in S. cerevisiae. DNA Repair (Amst) (2004) 0.98
During replication stress, non-SMC element 5 (NSE5) is required for Smc5/6 protein complex functionality at stalled forks. J Biol Chem (2012) 0.96
Rad52 sumoylation and its involvement in the efficient induction of homologous recombination. DNA Repair (Amst) (2008) 0.95
Rad5-dependent DNA repair functions of the Saccharomyces cerevisiae FANCM protein homolog Mph1. J Biol Chem (2012) 0.95
The Smc5-Smc6 complex regulates recombination at centromeric regions and affects kinetochore protein sumoylation during normal growth. PLoS One (2012) 0.90
DNA damage checkpoint and recombinational repair differentially affect the replication stress tolerance of Smc6 mutants. Mol Biol Cell (2013) 0.85
Mgs1 and Rad18/Rad5/Mms2 are required for survival of Saccharomyces cerevisiae mutants with novel temperature/cold sensitive alleles of the DNA polymerase delta subunit, Pol31. DNA Repair (Amst) (2006) 0.85
The SUMO protease SENP1 is required for cohesion maintenance and mitotic arrest following spindle poison treatment. Biochem Biophys Res Commun (2012) 0.84
Cohesion by topology: sister chromatids interlocked by DNA. Genes Dev (2008) 0.77