Published in FEBS J on April 04, 2008
Interaction between oligomers of stefin B and amyloid-beta in vitro and in cells. J Biol Chem (2009) 0.85
Pore formation by human stefin B in its native and oligomeric states and the consequent amyloid induced toxicity. Front Mol Neurosci (2012) 0.79
Human stefin B normal and patho-physiological role: molecular and cellular aspects of amyloid-type aggregation of certain EPM1 mutants. Front Mol Neurosci (2012) 0.77
Partial rotational lattice order-disorder in stefin B crystals. Acta Crystallogr D Biol Crystallogr (2014) 0.77
The role of initial oligomers in amyloid fibril formation by human stefin B. Int J Mol Sci (2013) 0.76
Human stefin B role in cell's response to misfolded proteins and autophagy. PLoS One (2014) 0.76
Mapping local structural perturbations in the native state of stefin B (cystatin B) under amyloid forming conditions. Front Mol Neurosci (2012) 0.76
Pore-Forming Proteins as Mediators of Novel Epigenetic Mechanism of Epilepsy. Front Neurol (2017) 0.75
Selective disruption of lysosomes in HeLa cells triggers apoptosis mediated by cleavage of Bid by multiple papain-like lysosomal cathepsins. J Biol Chem (2003) 2.30
Emerging roles of cysteine cathepsins in disease and their potential as drug targets. Curr Pharm Des (2007) 2.26
Cysteine cathepsins trigger caspase-dependent cell death through cleavage of bid and antiapoptotic Bcl-2 homologues. J Biol Chem (2008) 1.85
Lysosomes as "suicide bags" in cell death: myth or reality? J Biol Chem (2009) 1.65
Lysosomes and lysosomal cathepsins in cell death. Biochim Biophys Acta (2011) 1.61
Ferri-liposomes as an MRI-visible drug-delivery system for targeting tumours and their microenvironment. Nat Nanotechnol (2011) 1.41
Surface plasmon resonance in protein-membrane interactions. Chem Phys Lipids (2006) 1.38
Apoptotic pathways: involvement of lysosomal proteases. Biol Chem (2002) 1.38
A common toxin fold mediates microbial attack and plant defense. Proc Natl Acad Sci U S A (2009) 1.35
Autophagy is involved in nutritional stress response and differentiation in Trypanosoma cruzi. J Biol Chem (2007) 1.31
The role of miR-103 and miR-107 in regulation of CDK5R1 expression and in cellular migration. PLoS One (2011) 1.29
Lysosomal cysteine cathepsins: signaling pathways in apoptosis. Biol Chem (2007) 1.29
DNA-guided assembly of biosynthetic pathways promotes improved catalytic efficiency. Nucleic Acids Res (2011) 1.28
Protease signalling: the cutting edge. EMBO J (2012) 1.24
Essential role of proline isomerization in stefin B tetramer formation. J Mol Biol (2006) 1.23
Two-step membrane binding by Equinatoxin II, a pore-forming toxin from the sea anemone, involves an exposed aromatic cluster and a flexible helix. J Biol Chem (2002) 1.20
Intracellular and extracellular cathepsin B facilitate invasion of MCF-10A neoT cells through reconstituted extracellular matrix in vitro. Exp Cell Res (2003) 1.20
Peptides derived from apoptotic Bax and Bid reproduce the poration activity of the parent full-length proteins. Biophys J (2005) 1.19
Identifying the minimal copper- and zinc-binding site sequence in amyloid-beta peptides. J Biol Chem (2008) 1.18
Pore formation by equinatoxin II, a eukaryotic protein toxin, occurs by induction of nonlamellar lipid structures. J Biol Chem (2003) 1.17
Interaction between human cathepsins K, L, and S and elastins: mechanism of elastinolysis and inhibition by macromolecular inhibitors. J Biol Chem (2007) 1.14
Lysosomes in apoptosis. Methods Enzymol (2008) 1.13
Expression and activity profiling of selected cysteine cathepsins and matrix metalloproteinases in synovial fluids from patients with rheumatoid arthritis and osteoarthritis. Biol Chem (2010) 1.13
Widespread uncoupling between transcriptome and translatome variations after a stimulus in mammalian cells. BMC Genomics (2012) 1.12
Metacaspases of Trypanosoma cruzi: possible candidates for programmed cell death mediators. Mol Biochem Parasitol (2005) 1.10
Toxin detection by surface plasmon resonance. Sensors (Basel) (2009) 1.10
Lipid phase coexistence favors membrane insertion of equinatoxin-II, a pore-forming toxin from Actinia equina. J Biol Chem (2004) 1.09
Molecular determinants of sphingomyelin specificity of a eukaryotic pore-forming toxin. J Biol Chem (2008) 1.09
Solution structure of the eukaryotic pore-forming cytolysin equinatoxin II: implications for pore formation. J Mol Biol (2002) 1.08
Probing HIV-1 membrane liquid order by Laurdan staining reveals producer cell-dependent differences. J Biol Chem (2009) 1.07
Exoerythrocytic Plasmodium parasites secrete a cysteine protease inhibitor involved in sporozoite invasion and capable of blocking cell death of host hepatocytes. PLoS Pathog (2010) 1.07
Molecular mechanism of pore formation by actinoporins. Toxicon (2009) 1.07
Stefin B interacts with histones and cathepsin L in the nucleus. J Biol Chem (2010) 1.04
Kinetics of cholesterol extraction from lipid membranes by methyl-beta-cyclodextrin--a surface plasmon resonance approach. Biochim Biophys Acta (2007) 1.04
Glycosaminoglycans facilitate procathepsin B activation through disruption of propeptide-mature enzyme interactions. J Biol Chem (2007) 1.04
Intracellular proteolytic activity of cathepsin B is associated with capillary-like tube formation by endothelial cells in vitro. J Cell Biochem (2006) 1.04
Human perforin employs different avenues to damage membranes. J Biol Chem (2010) 1.03
Pore formation by equinatoxin, a eukaryotic pore-forming toxin, requires a flexible N-terminal region and a stable beta-sandwich. J Biol Chem (2004) 1.03
Autocatalytic processing of procathepsin B is triggered by proenzyme activity. FEBS J (2009) 1.02
A novel mechanism of pore formation: membrane penetration by the N-terminal amphipathic region of equinatoxin. J Biol Chem (2003) 1.02
Carboxypeptidases cathepsins X and B display distinct protein profile in human cells and tissues. Exp Cell Res (2005) 1.02
Lysosomal cysteine proteases: structural features and their role in apoptosis. IUBMB Life (2005) 1.01
Equinatoxin II permeabilizing activity depends on the presence of sphingomyelin and lipid phase coexistence. Biophys J (2008) 1.01
Effects of MACPF/CDC proteins on lipid membranes. Cell Mol Life Sci (2012) 1.00
Recombinant human procathepsin S is capable of autocatalytic processing at neutral pH in the presence of glycosaminoglycans. FEBS Lett (2005) 1.00
Structures of lysenin reveal a shared evolutionary origin for pore-forming proteins and its mode of sphingomyelin recognition. Structure (2012) 0.99
A toxin-based probe reveals cytoplasmic exposure of Golgi sphingomyelin. J Biol Chem (2010) 0.99
Diversity and evolution of the thyroglobulin type-1 domain superfamily. Mol Biol Evol (2005) 0.98
Sterol and pH interdependence in the binding, oligomerization, and pore formation of Listeriolysin O. Biochemistry (2007) 0.98
Downregulation of HuR as a new mechanism of doxorubicin resistance in breast cancer cells. Mol Cancer (2012) 0.98
The novel bovine serpin endopin 2C demonstrates selective inhibition of the cysteine protease cathepsin L compared to the serine protease elastase, in cross-class inhibition. Biochemistry (2005) 0.98
Perforin rapidly induces plasma membrane phospholipid flip-flop. PLoS One (2011) 0.97
Biological characterization of white line-inducing principle (WLIP) produced by Pseudomonas reactans NCPPB1311. Mol Plant Microbe Interact (2006) 0.96
Interconversion between bound and free conformations of LexA orchestrates the bacterial SOS response. Nucleic Acids Res (2011) 0.95
Oligomerization and pore formation by equinatoxin II inhibit endocytosis and lead to plasma membrane reorganization. J Biol Chem (2011) 0.94
Membrane damage by an α-helical pore-forming protein, Equinatoxin II, proceeds through a succession of ordered steps. J Biol Chem (2013) 0.94
Selective activity-based probes for cysteine cathepsins. Angew Chem Int Ed Engl (2008) 0.94
pH dependence of listeriolysin O aggregation and pore-forming ability. FEBS J (2011) 0.94
Phylogenomic analysis of the cystatin superfamily in eukaryotes and prokaryotes. BMC Evol Biol (2009) 0.93
Inhibitory properties of cystatin F and its localization in U937 promonocyte cells. FEBS J (2005) 0.93
Interaction of human stefin B in the prefibrillar oligomeric form with membranes. Correlation with cellular toxicity. FEBS J (2005) 0.93
Protein engineering modulates the transport properties and ion selectivity of the pores formed by staphylococcal gamma-haemolysins in lipid membranes. Mol Microbiol (2002) 0.92
Single peptide bonds exhibit poly(pro)II ("random coil") circular dichroism spectra. J Am Chem Soc (2005) 0.92
In vitro study of stability and amyloid-fibril formation of two mutants of human stefin B (cystatin B) occurring in patients with EPM1. Protein Sci (2005) 0.91
A global benchmark study using affinity-based biosensors. Anal Biochem (2008) 0.91
Structure-based discovery of substituted 4,5'-bithiazoles as novel DNA gyrase inhibitors. J Med Chem (2012) 0.91
Human stefin B readily forms amyloid fibrils in vitro. Biochim Biophys Acta (2002) 0.91
High prevalence of enteric viruses in untreated individual drinking water sources and surface water in Slovenia. Int J Hyg Environ Health (2011) 0.90
The equinatoxin N-terminus is transferred across planar lipid membranes and helps to stabilize the transmembrane pore. FEBS J (2007) 0.89
Recombinant human cathepsin H lacking the mini chain is an endopeptidase. Biochemistry (2003) 0.89
Potentiation of anticancer-drug cytotoxicity by sea anemone pore-forming proteins in human glioblastoma cells. Anticancer Drugs (2008) 0.89
Mechanisms of amyloid fibril formation--focus on domain-swapping. FEBS J (2011) 0.89
Purification, cloning and characterization of fragaceatoxin C, a novel actinoporin from the sea anemone Actinia fragacea. Toxicon (2009) 0.89
Alpha-synuclein pore forming activity upon membrane association. Biochim Biophys Acta (2012) 0.89
Capture of intact liposomes on biacore sensor chips for protein-membrane interaction studies. Methods Mol Biol (2010) 0.88
Membrane insertion of the N-terminal alpha-helix of equinatoxin II, a sea anemone cytolytic toxin. Biochem J (2004) 0.88
Inhibition of MAPK/ERK, PKC and CaMKII signaling blocks cytolysin-induced human glioma cell death. Anticancer Res (2010) 0.88
Effects of the eukaryotic pore-forming cytolysin Equinatoxin II on lipid membranes and the role of sphingomyelin. Biophys J (2003) 0.88
The mechanism of amyloid-fibril formation by stefin B: temperature and protein concentration dependence of the rates. Proteins (2009) 0.87
Effect of pH on the pore forming activity and conformational stability of ostreolysin, a lipid raft-binding protein from the edible mushroom Pleurotus ostreatus. Biochemistry (2005) 0.87
Engineered covalent leucotoxin heterodimers form functional pores: insights into S-F interactions. Biochem J (2006) 0.87
Human perforin permeabilizing activity, but not binding to lipid membranes, is affected by pH. Mol Immunol (2010) 0.87
Recombinant human SMOCs produced by in vitro refolding: calcium-binding properties and interactions with serum proteins. Protein Expr Purif (2008) 0.87