Published in Nat Rev Genet on May 01, 2008
Oscillating gene expression determines competence for periodic Arabidopsis root branching. Science (2010) 3.26
Topology and dynamics of the zebrafish segmentation clock core circuit. PLoS Biol (2012) 2.41
Multiplexed and programmable regulation of gene networks with an integrated RNA and CRISPR/Cas toolkit in human cells. Mol Cell (2014) 2.02
Homeotic effects, somitogenesis and the evolution of vertebral numbers in recent and fossil amniotes. Proc Natl Acad Sci U S A (2010) 1.98
Scaling of embryonic patterning based on phase-gradient encoding. Nature (2012) 1.91
Signaling mechanisms controlling cell fate and embryonic patterning. Cold Spring Harb Perspect Biol (2012) 1.89
Boundary formation and maintenance in tissue development. Nat Rev Genet (2011) 1.78
Signaling gradients during paraxial mesoderm development. Cold Spring Harb Perspect Biol (2010) 1.73
Vertebrate segmentation: from cyclic gene networks to scoliosis. Cell (2011) 1.65
The gap gene network. Cell Mol Life Sci (2010) 1.51
Canonical Wnt signaling dynamically controls multiple stem cell fate decisions during vertebrate body formation. Dev Cell (2012) 1.43
Global control of motor neuron topography mediated by the repressive actions of a single hox gene. Neuron (2010) 1.41
Evolutionary plasticity of segmentation clock networks. Development (2011) 1.39
Intronic delay is essential for oscillatory expression in the segmentation clock. Proc Natl Acad Sci U S A (2011) 1.37
Quantitative approaches in developmental biology. Nat Rev Genet (2009) 1.34
Cell-specific interaction of retinoic acid receptors with target genes in mouse embryonic fibroblasts and embryonic stem cells. Mol Cell Biol (2010) 1.30
Developmental control of segment numbers in vertebrates. J Exp Zool B Mol Dev Evol (2009) 1.28
Rere controls retinoic acid signalling and somite bilateral symmetry. Nature (2010) 1.27
FGF4 and FGF8 comprise the wavefront activity that controls somitogenesis. Proc Natl Acad Sci U S A (2011) 1.23
ACME: automated cell morphology extractor for comprehensive reconstruction of cell membranes. PLoS Comput Biol (2012) 1.19
Vertebral architecture in the earliest stem tetrapods. Nature (2013) 1.14
A novel reporter of notch signalling indicates regulated and random Notch activation during vertebrate neurogenesis. BMC Biol (2011) 1.14
Notch is a critical component of the mouse somitogenesis oscillator and is essential for the formation of the somites. PLoS Genet (2009) 1.14
The Wnt3a/β-catenin target gene Mesogenin1 controls the segmentation clock by activating a Notch signalling program. Nat Commun (2011) 1.07
Spatiotemporal compartmentalization of key physiological processes during muscle precursor differentiation. Proc Natl Acad Sci U S A (2010) 1.06
Interfering with Wnt signalling alters the periodicity of the segmentation clock. Dev Biol (2009) 1.05
Spots and stripes: pleomorphic patterning of stem cells via p-ERK-dependent cell chemotaxis shown by feather morphogenesis and mathematical simulation. Dev Biol (2009) 1.03
Genome-wide analysis of a Wnt1-regulated transcriptional network implicates neurodegenerative pathways. Sci Signal (2011) 1.03
Different types of oscillations in Notch and Fgf signaling regulate the spatiotemporal periodicity of somitogenesis. Genes Dev (2011) 1.02
The segmentation clock mechanism moves up a notch. Trends Cell Biol (2010) 1.01
Comparison of pattern detection methods in microarray time series of the segmentation clock. PLoS One (2008) 0.99
Mutations in the MESP2 gene cause spondylothoracic dysostosis/Jarcho-Levin syndrome. Am J Hum Genet (2008) 0.97
Transitions between epithelial and mesenchymal states and the morphogenesis of the early mouse embryo. Cell Adh Migr (2010) 0.95
Somitogenesis. Development (2012) 0.95
Cyclical expression of the Notch/Wnt regulator Nrarp requires modulation by Dll3 in somitogenesis. Dev Biol (2009) 0.94
Wnt-dependent epithelial transitions drive pharyngeal pouch formation. Dev Cell (2013) 0.93
Dynamic 3D cell rearrangements guided by a fibronectin matrix underlie somitogenesis. PLoS One (2009) 0.93
Ultradian oscillations and pulses: coordinating cellular responses and cell fate decisions. Development (2014) 0.92
Retinoic acid controls body axis extension by directly repressing Fgf8 transcription. Development (2014) 0.91
Skeletal myogenesis and Myf5 activation. Transcription (2011) 0.91
The differentiation and movement of presomitic mesoderm progenitor cells are controlled by Mesogenin 1. Development (2012) 0.91
The chick somitogenesis oscillator is arrested before all paraxial mesoderm is segmented into somites. BMC Dev Biol (2010) 0.90
Gene length may contribute to graded transcriptional responses in the Drosophila embryo. Dev Biol (2011) 0.90
The microRNA-processing enzyme Dicer is dispensable for somite segmentation but essential for limb bud positioning. Dev Biol (2011) 0.89
Cyclic Nrarp mRNA expression is regulated by the somitic oscillator but Nrarp protein levels do not oscillate. Dev Dyn (2009) 0.89
Congenital scoliosis in monozygotic twins: case report and review of possible factors contributing to its development. Scoliosis (2008) 0.89
Mesogenin 1 is a master regulator of paraxial presomitic mesoderm differentiation. Development (2014) 0.88
Intercellular communication during plant development. Plant Cell (2011) 0.88
From lizard to snake; behind the evolution of an extreme body plan. Curr Genomics (2012) 0.87
Travelling and splitting of a wave of hedgehog expression involved in spider-head segmentation. Nat Commun (2011) 0.87
The mouse notches up another success: understanding the causes of human vertebral malformation. Mamm Genome (2011) 0.86
Interplay between a Wnt-dependent organiser and the Notch segmentation clock regulates posterior development in Periplaneta americana. Biol Open (2012) 0.86
Origin of muscle satellite cells in the Xenopus embryo. Development (2011) 0.86
A spatio-temporal model of Notch signalling in the zebrafish segmentation clock: conditions for synchronised oscillatory dynamics. PLoS One (2011) 0.86
Spatiotemporal oscillations of Notch1, Dll1 and NICD are coordinated across the mouse PSM. Development (2014) 0.85
Uncoupling of retinoic acid signaling from tailbud development before termination of body axis extension. Genesis (2011) 0.85
Somitogenesis clock-wave initiation requires differential decay and multiple binding sites for clock protein. PLoS Comput Biol (2010) 0.85
What is a segment? Evodevo (2013) 0.85
Canine disorder mirrors human disease: exonic deletion in HES7 causes autosomal recessive spondylocostal dysostosis in miniature Schnauzer dogs. PLoS One (2015) 0.84
A fluorescence spotlight on the clockwork development and metabolism of bone. J Bone Miner Metab (2011) 0.84
Mechanisms of side branching and tip splitting in a model of branching morphogenesis. PLoS One (2014) 0.84
Sprouty4, an FGF inhibitor, displays cyclic gene expression under the control of the notch segmentation clock in the mouse PSM. PLoS One (2009) 0.83
Mathematical models for the Notch and Wnt signaling pathways and the crosstalk between them during somitogenesis. Theor Biol Med Model (2013) 0.83
microRNA input into a neural ultradian oscillator controls emergence and timing of alternative cell states. Nat Commun (2014) 0.83
Extensive molecular differences between anterior- and posterior-half-sclerotomes underlie somite polarity and spinal nerve segmentation. BMC Dev Biol (2009) 0.82
Sequence-based model of gap gene regulatory network. BMC Genomics (2014) 0.81
Notch signaling does not regulate segmentation in the honeybee, Apis mellifera. Dev Genes Evol (2010) 0.81
Anterior-posterior patterning and segmentation of the vertebrate head. Integr Comp Biol (2008) 0.81
A context-dependent combination of Wnt receptors controls axis elongation and leg development in a short germ insect. Development (2011) 0.81
From dynamic expression patterns to boundary formation in the presomitic mesoderm. PLoS Comput Biol (2012) 0.81
A transgenic Tbx6;CreERT2 line for inducible gene manipulation in the presomitic mesoderm. Genesis (2011) 0.81
Dhrs3 protein attenuates retinoic acid signaling and is required for early embryonic patterning. J Biol Chem (2013) 0.80
Mechanisms and constraints shaping the evolution of body plan segmentation. Eur Phys J E Soft Matter (2013) 0.80
Global Developmental Gene Programing Involves a Nuclear Form of Fibroblast Growth Factor Receptor-1 (FGFR1). PLoS One (2015) 0.80
Retinoic acid-dependent regulation of miR-19 expression elicits vertebrate axis defects. FASEB J (2013) 0.79
The synchrony and cyclicity of developmental events. Cold Spring Harb Perspect Biol (2012) 0.79
NDR Kinases Are Essential for Somitogenesis and Cardiac Looping during Mouse Embryonic Development. PLoS One (2015) 0.79
The Notch-regulated ankyrin repeat protein is required for proper anterior-posterior somite patterning in mice. Genesis (2012) 0.79
Dynamic CREB family activity drives segmentation and posterior polarity specification in mammalian somitogenesis. Proc Natl Acad Sci U S A (2013) 0.79
Heterochrony and developmental timing mechanisms: changing ontogenies in evolution. Semin Cell Dev Biol (2014) 0.79
How can mathematics help us explore vertebrate segmentation? HFSP J (2009) 0.79
Live imaging-based model selection reveals periodic regulation of the stochastic G1/S phase transition in vertebrate axial development. PLoS Comput Biol (2014) 0.78
Biogenesis and Biological Activity of Secondary siRNAs in Plants. Scientifica (Cairo) (2013) 0.78
The precise timeline of transcriptional regulation reveals causation in mouse somitogenesis network. BMC Dev Biol (2013) 0.78
Wnt3a signal pathways activate MyoD expression by targeting cis-elements inside and outside its distal enhancer. Biosci Rep (2015) 0.78
Evidence-Based Theory for Integrated Genome Regulation of Ontogeny-An Unprecedented Role of Nuclear FGFR1 Signaling. J Cell Physiol (2016) 0.78
The myotomal basement membrane: insight into laminin-111 function and its control by Sonic hedgehog signaling. Cell Adh Migr (2013) 0.78
A novel gain-of-function mutation of the proneural IRX1 and IRX2 genes disrupts axis elongation in the Araucana rumpless chicken. PLoS One (2014) 0.77
Left-right function of dmrt2 genes is not conserved between zebrafish and mouse. PLoS One (2010) 0.77
Evolution of the Role of RA and FGF Signals in the Control of Somitogenesis in Chordates. PLoS One (2015) 0.77
'Monster… -omics': on segmentation, re-segmentation, and vertebrae formation in amphibians and other vertebrates. Front Zool (2013) 0.77
Generation of dispersed presomitic mesoderm cell cultures for imaging of the zebrafish segmentation clock in single cells. J Vis Exp (2014) 0.77
Modelling coupled oscillations in the Notch, Wnt, and FGF signaling pathways during somitogenesis: a comprehensive mathematical model. Comput Intell Neurosci (2015) 0.77
Stochastic Regulation of her1/7 Gene Expression Is the Source of Noise in the Zebrafish Somite Clock Counteracted by Notch Signalling. PLoS Comput Biol (2015) 0.76
The alternative splicing regulator Tra2b is required for somitogenesis and regulates splicing of an inhibitory Wnt11b isoform. Cell Rep (2015) 0.76
Phenotype characterization of embryoid body structures generated by a crystal comet effect tail in an intercellular cancer collision scenario. Cancer Manag Res (2012) 0.76
The role of Wnt regulation in heart development, cardiac repair and disease: A tissue engineering perspective. Biochem Biophys Res Commun (2015) 0.76
Fast synchronization of ultradian oscillators controlled by delta-notch signaling with cis-inhibition. PLoS Comput Biol (2014) 0.75
A gene regulation network controlled by Celf1 protein-rbpj mRNA interaction in Xenopus somite segmentation. Biol Open (2013) 0.75
A complex oscillating network of signaling genes underlies the mouse segmentation clock. Science (2006) 3.27
Control of segment number in vertebrate embryos. Nature (2008) 2.78
fgf8 mRNA decay establishes a gradient that couples axial elongation to patterning in the vertebrate embryo. Nature (2004) 2.77
A beta-catenin gradient links the clock and wavefront systems in mouse embryo segmentation. Nat Cell Biol (2007) 2.01
Retinoic acid coordinates somitogenesis and left-right patterning in vertebrate embryos. Nature (2005) 1.84
Signaling gradients during paraxial mesoderm development. Cold Spring Harb Perspect Biol (2010) 1.73
A random cell motility gradient downstream of FGF controls elongation of an amniote embryo. Nature (2010) 1.58
Coupling segmentation to axis formation. Development (2004) 1.52
Collinear activation of Hoxb genes during gastrulation is linked to mesoderm cell ingression. Nature (2006) 1.51
Changes in Hox genes' structure and function during the evolution of the squamate body plan. Nature (2010) 1.43
Control of the segmentation process by graded MAPK/ERK activation in the chick embryo. Proc Natl Acad Sci U S A (2005) 1.42
Modeling the segmentation clock as a network of coupled oscillations in the Notch, Wnt and FGF signaling pathways. J Theor Biol (2008) 1.41
FGF signaling acts upstream of the NOTCH and WNT signaling pathways to control segmentation clock oscillations in mouse somitogenesis. Development (2007) 1.40
Abnormal vertebral segmentation and the notch signaling pathway in man. Dev Dyn (2007) 1.39
Evolutionary plasticity of segmentation clock networks. Development (2011) 1.39
Oscillations of the snail genes in the presomitic mesoderm coordinate segmental patterning and morphogenesis in vertebrate somitogenesis. Dev Cell (2006) 1.36
Sharp developmental thresholds defined through bistability by antagonistic gradients of retinoic acid and FGF signaling. Dev Dyn (2007) 1.30
Developmental control of segment numbers in vertebrates. J Exp Zool B Mol Dev Evol (2009) 1.28
Rere controls retinoic acid signalling and somite bilateral symmetry. Nature (2010) 1.27
Oscillating signaling pathways during embryonic development. Curr Opin Cell Biol (2008) 1.23
Hox genes in time and space during vertebrate body formation. Dev Growth Differ (2007) 1.20
Axon fasciculation defects and retinal dysplasias in mice lacking the immunoglobulin superfamily adhesion molecule BEN/ALCAM/SC1. Mol Cell Neurosci (2004) 1.20
Incomplete penetrance and phenotypic variability characterize Gdf6-attributable oculo-skeletal phenotypes. Hum Mol Genet (2009) 1.14
Establishment of Hox vertebral identities in the embryonic spine precursors. Curr Top Dev Biol (2009) 1.12
Sex-dimorphic gene expression and ineffective dosage compensation of Z-linked genes in gastrulating chicken embryos. BMC Genomics (2010) 1.11
Synchronised cycling gene oscillations in presomitic mesoderm cells require cell-cell contact. Int J Dev Biol (2005) 1.10
Spatiotemporal compartmentalization of key physiological processes during muscle precursor differentiation. Proc Natl Acad Sci U S A (2010) 1.06
Synthesis of new 3-alkoxy-7-amino-4-chloro-isocoumarin derivatives as new beta-amyloid peptide production inhibitors and their activities on various classes of protease. Bioorg Med Chem (2003) 1.00
Formation and segmentation of the vertebrate body axis. Annu Rev Cell Dev Biol (2013) 0.99
Comparison of pattern detection methods in microarray time series of the segmentation clock. PLoS One (2008) 0.99
The vertebrate segmentation clock: the tip of the iceberg. Curr Opin Genet Dev (2008) 0.98
Progress in the understanding of the genetic etiology of vertebral segmentation disorders in humans. Ann N Y Acad Sci (2009) 0.98
Manteia, a predictive data mining system for vertebrate genes and its applications to human genetic diseases. Nucleic Acids Res (2013) 0.97
Mutations in the MESP2 gene cause spondylothoracic dysostosis/Jarcho-Levin syndrome. Am J Hum Genet (2008) 0.97
Lighting up developmental mechanisms: how fluorescence imaging heralded a new era. Development (2010) 0.92
On periodicity and directionality of somitogenesis. Anat Embryol (Berl) (2006) 0.88
From head to tail: links between the segmentation clock and antero-posterior patterning of the embryo. Curr Opin Genet Dev (2002) 0.87
Tissue micromanipulation in zebrafish embryos. Methods Mol Biol (2009) 0.87
Dual mode of paraxial mesoderm formation during chick gastrulation. Proc Natl Acad Sci U S A (2007) 0.85
In vivo analysis of mRNA stability using the Tet-Off system in the chicken embryo. Dev Biol (2005) 0.82
Chicken genome: new tools and concepts. Dev Dyn (2005) 0.81
Molecular diagnosis of vertebral segmentation disorders in humans. Expert Opin Med Diagn (2008) 0.80
Making the clock tick: right time, right pace. Dev Cell (2013) 0.78
Retinoic acid. Curr Biol (2008) 0.78
Manipulation and electroporation of the avian segmental plate and somites in vitro. Methods Cell Biol (2008) 0.77
Developmental biology: cell intercalation one step beyond. Curr Biol (2008) 0.77
Reprogramming development. Development (2013) 0.77
Signal transduction: a new canon. Nature (2005) 0.77
Looking inwards: opening a window onto human development. Development (2015) 0.76
BEN/DM-GRASP/SC1 expression during mouse facial development: differential expression and regulation in molars and incisors. Gene Expr Patterns (2003) 0.76
Development: looking to the future. Development (2012) 0.76
Poultry genomics puts meat on the table. Comp Funct Genomics (2005) 0.75
Stem cells and regeneration: a special issue. Development (2013) 0.75
Steering a changing course. Development (2011) 0.75
The San Francisco declaration on research assessment. Development (2013) 0.75
Pattern formation and developmental mechanisms. Curr Opin Genet Dev (2008) 0.75
[A non directional cell migration gradient in the presomitic mesoderm contributes to axis elongation in chicken embryos]. Biol Aujourdhui (2011) 0.75
Going format-free. Development (2017) 0.75
The Node: a place to discuss, debate and deliberate developmental biology. Development (2010) 0.75
Editorial on segmentation focus. Dev Dyn (2007) 0.75
Entrails, heart, brain, limbs, and lymphatics- a recipe for success? Dev Cell (2003) 0.75