Marius Wernig

Author PubWeight™ 317.72‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Genome-wide maps of chromatin state in pluripotent and lineage-committed cells. Nature 2007 65.18
2 A bivalent chromatin structure marks key developmental genes in embryonic stem cells. Cell 2006 48.80
3 Genome-scale DNA methylation maps of pluripotent and differentiated cells. Nature 2008 30.29
4 Polycomb complexes repress developmental regulators in murine embryonic stem cells. Nature 2006 25.90
5 Direct conversion of fibroblasts to functional neurons by defined factors. Nature 2010 18.76
6 Dissecting direct reprogramming through integrative genomic analysis. Nature 2008 16.47
7 Connecting microRNA genes to the core transcriptional regulatory circuitry of embryonic stem cells. Cell 2008 16.38
8 Treatment of sickle cell anemia mouse model with iPS cells generated from autologous skin. Science 2007 12.41
9 Sequential expression of pluripotency markers during direct reprogramming of mouse somatic cells. Cell Stem Cell 2008 12.29
10 Direct reprogramming of terminally differentiated mature B lymphocytes to pluripotency. Cell 2008 10.68
11 Direct reprogramming of genetically unmodified fibroblasts into pluripotent stem cells. Nat Biotechnol 2007 9.04
12 c-Myc is dispensable for direct reprogramming of mouse fibroblasts. Cell Stem Cell 2007 8.46
13 Induction of human neuronal cells by defined transcription factors. Nature 2011 6.84
14 Direct conversion of mouse fibroblasts to self-renewing, tripotent neural precursor cells. Proc Natl Acad Sci U S A 2012 3.52
15 Direct lineage conversions: unnatural but useful? Nat Biotechnol 2011 2.69
16 Generation of oligodendroglial cells by direct lineage conversion. Nat Biotechnol 2013 2.64
17 In situ genetic correction of the sickle cell anemia mutation in human induced pluripotent stem cells using engineered zinc finger nucleases. Stem Cells 2011 2.52
18 Rapid single-step induction of functional neurons from human pluripotent stem cells. Neuron 2013 2.51
19 Direct lineage conversion of terminally differentiated hepatocytes to functional neurons. Cell Stem Cell 2011 2.49
20 Telomere shortening and loss of self-renewal in dyskeratosis congenita induced pluripotent stem cells. Nature 2011 2.03
21 Generation of iPSCs from cultured human malignant cells. Blood 2010 1.99
22 Hierarchical mechanisms for direct reprogramming of fibroblasts to neurons. Cell 2013 1.92
23 Induced neuronal cells: how to make and define a neuron. Cell Stem Cell 2011 1.77
24 Molecular roadblocks for cellular reprogramming. Mol Cell 2012 1.74
25 Comprehensive qPCR profiling of gene expression in single neuronal cells. Nat Protoc 2011 1.73
26 Functional characterization of cardiomyocytes derived from murine induced pluripotent stem cells in vitro. FASEB J 2009 1.52
27 FOXO3 shares common targets with ASCL1 genome-wide and inhibits ASCL1-dependent neurogenesis. Cell Rep 2013 1.45
28 Comparison of contractile behavior of native murine ventricular tissue and cardiomyocytes derived from embryonic or induced pluripotent stem cells. FASEB J 2010 1.45
29 Functional integration of embryonic stem cell-derived neurons in hippocampal slice cultures. J Neurosci 2003 1.32
30 Neurons generated by direct conversion of fibroblasts reproduce synaptic phenotype caused by autism-associated neuroligin-3 mutation. Proc Natl Acad Sci U S A 2013 1.09
31 The many roads to Rome: induction of neural precursor cells from fibroblasts. Curr Opin Genet Dev 2012 1.08
32 Cardiac myocytes derived from murine reprogrammed fibroblasts: intact hormonal regulation, cardiac ion channel expression and development of contractility. Cell Physiol Biochem 2009 1.02
33 The vast majority of bone-marrow-derived cells integrated into mdx muscle fibers are silent despite long-term engraftment. Proc Natl Acad Sci U S A 2005 0.96
34 Analysis of conditional heterozygous STXBP1 mutations in human neurons. J Clin Invest 2015 0.95
35 Cellular reprogramming: recent advances in modeling neurological diseases. J Neurosci 2011 0.92
36 Induced neuronal reprogramming. J Comp Neurol 2014 0.85
37 Migration and differentiation of myogenic precursors following transplantation into the developing rat brain. Stem Cells 2003 0.83
38 Acute reduction in oxygen tension enhances the induction of neurons from human fibroblasts. J Neurosci Methods 2013 0.83
39 An indirect approach to generating specific human cell types. Nat Methods 2013 0.77
40 Harnessing the stem cell potential: a case for neural stem cell therapy. Nat Med 2013 0.77
41 An imprinted signature helps isolate ESC-equivalent iPSCs. Cell Res 2010 0.76
42 Corrigendum: Hallmarks of pluripotency. Nature 2015 0.75
43 Corrigendum: Failure to replicate the STAP cell phenomenon. Nature 2015 0.75
44 On the streets of San Francisco: highlights from the ISSCR Annual Meeting 2010. Cell Stem Cell 2010 0.75