Published in Ophthalmology on June 01, 2008
Genetic testing in persons with age-related macular degeneration and the use of the AREDS supplements: to test or not to test? Ophthalmology (2014) 4.00
Molecular pathology of age-related macular degeneration. Prog Retin Eye Res (2008) 3.35
Prediction model for prevalence and incidence of advanced age-related macular degeneration based on genetic, demographic, and environmental variables. Invest Ophthalmol Vis Sci (2008) 2.91
No clinically significant association between CFH and ARMS2 genotypes and response to nutritional supplements: AREDS report number 38. Ophthalmology (2014) 2.86
Unraveling a multifactorial late-onset disease: from genetic susceptibility to disease mechanisms for age-related macular degeneration. Annu Rev Genomics Hum Genet (2009) 2.40
Pharmacogenetics of complement factor H (Y402H) and treatment of exudative age-related macular degeneration with ranibizumab. Br J Ophthalmol (2008) 1.47
Mitochondrial function and redox control in the aging eye: role of MsrA and other repair systems in cataract and macular degenerations. Exp Eye Res (2008) 1.47
Complement, age-related macular degeneration and a vision of the future. Arch Ophthalmol (2010) 1.42
Age-related macular degeneration: genetic and environmental factors of disease. Mol Interv (2010) 1.24
A2E induces IL-1ß production in retinal pigment epithelial cells via the NLRP3 inflammasome. PLoS One (2013) 1.22
The influence of genetics on response to treatment with ranibizumab (Lucentis) for age-related macular degeneration: the Lucentis Genotype Study (an American Ophthalmological Society thesis). Trans Am Ophthalmol Soc (2011) 1.18
The significance of the complement system for the pathogenesis of age-related macular degeneration - current evidence and translation into clinical application. Graefes Arch Clin Exp Ophthalmol (2010) 1.12
Genetic studies of age-related macular degeneration: lessons, challenges, and opportunities for disease management. Ophthalmology (2012) 1.07
Genetics of immunological and inflammatory components in age-related macular degeneration. Ocul Immunol Inflamm (2012) 1.04
Association between dietary fat intake and age-related macular degeneration in the Carotenoids in Age-Related Eye Disease Study (CAREDS): an ancillary study of the Women's Health Initiative. Arch Ophthalmol (2009) 1.02
Age-related macular degeneration-clinical review and genetics update. Clin Genet (2013) 1.00
Association between variant Y402H in age-related macular degeneration (AMD) susceptibility gene CFH and treatment response of AMD: a meta-analysis. PLoS One (2012) 0.94
Pharmacogenetics and age-related macular degeneration. J Ophthalmol (2011) 0.94
Genome-wide association analyses of genetic, phenotypic, and environmental risks in the age-related eye disease study. Mol Vis (2010) 0.91
Perspective: A Critical Look at the Ancillary Age-Related Eye Disease Study 2: Nutrition and Cognitive Function Results in Older Individuals with Age-Related Macular Degeneration. Adv Nutr (2016) 0.89
Functional effect of Saffron supplementation and risk genotypes in early age-related macular degeneration: a preliminary report. J Transl Med (2013) 0.89
Clinical and genetic factors associated with progression of geographic atrophy lesions in age-related macular degeneration. PLoS One (2015) 0.87
Zinc supplementation inhibits complement activation in age-related macular degeneration. PLoS One (2014) 0.86
Complement pathway biomarkers and age-related macular degeneration. Eye (Lond) (2015) 0.86
Zinc binding to the Tyr402 and His402 allotypes of complement factor H: possible implications for age-related macular degeneration. J Mol Biol (2011) 0.86
Genetic and environmental underpinnings to age-related ocular diseases. Invest Ophthalmol Vis Sci (2013) 0.85
Update on the role of genetics in the onset of age-related macular degeneration. Clin Ophthalmol (2011) 0.83
Zinc-induced self-association of complement C3b and Factor H: implications for inflammation and age-related macular degeneration. J Biol Chem (2013) 0.82
Cfh genotype interacts with dietary glycemic index to modulate age-related macular degeneration-like features in mice. Invest Ophthalmol Vis Sci (2014) 0.80
[Etiology and pathogenesis of age-related macular degeneration]. Ophthalmologe (2013) 0.80
Emerging roles for nuclear receptors in the pathogenesis of age-related macular degeneration. Cell Mol Life Sci (2014) 0.80
Complement Factor H Y402H and LOC387715 A69S Polymorphisms in Association with Age-Related Macular Degeneration in Iran. J Ophthalmic Vis Res (2014) 0.79
Polymorphisms in ARMS2/HTRA1 and complement genes and age-related macular degeneration in India: findings from the INDEYE study. Invest Ophthalmol Vis Sci (2012) 0.78
Association Between Vitamin D Status and Age-Related Macular Degeneration by Genetic Risk. JAMA Ophthalmol (2015) 0.78
Joint Associations of Diet, Lifestyle, and Genes with Age-Related Macular Degeneration. Ophthalmology (2015) 0.78
Genetic risk, ethnic variations and pharmacogenetic biomarkers in age-related macular degeneration and polypoidal choroidal vasculopathy. Expert Rev Ophthalmol (2013) 0.77
Increased retinal mtDNA damage in the CFH variant associated with age-related macular degeneration. Exp Eye Res (2016) 0.77
Genetics and age-related macular degeneration: a practical review for the clinician. Clin Ophthalmol (2016) 0.77
Adherence to a Mediterranean diet, genetic susceptibility, and progression to advanced macular degeneration: a prospective cohort study. Am J Clin Nutr (2015) 0.77
CFH Y402H and ARMS2 A69S Polymorphisms and Oral Supplementation with Docosahexaenoic Acid in Neovascular Age-Related Macular Degeneration Patients: The NAT2 Study. PLoS One (2015) 0.77
Pharmacogenetics and nutritional supplementation in age-related macular degeneration. Clin Ophthalmol (2015) 0.76
CFH and LOC387715/ARMS2 genotypes and antioxidants and zinc therapy for age-related macular degeneration. Pharmacogenomics (2008) 0.76
Genetic diversity and medicinal drug response in eye care. Graefes Arch Clin Exp Ophthalmol (2010) 0.76
Alterations of choroidal blood flow regulation in young healthy subjects with complement factor H polymorphism. PLoS One (2013) 0.76
Pharmacogenetic influence of LOC387715/HTRA1 on the efficacy of bevacizumab treatment for age-related macular degeneration in a Korean population. Korean J Ophthalmol (2012) 0.75
Genetics of age-related macular degeneration: application to drug design. Future Med Chem (2013) 0.75
[Genetic and risk factors for exudative AMD]. Ophthalmologe (2010) 0.75
Enhanced Detection of Sub-Retinal Pigment Epithelial Cell Layer Deposits in Human and Murine Tissue: Imaging Zinc as a Biomarker for Age-Related Macular Degeneration (An American Ophthalmological Society Thesis). Trans Am Ophthalmol Soc (2017) 0.75
Complement factor H polymorphism in age-related macular degeneration. Science (2005) 31.10
Interaction between the serotonin transporter gene (5-HTTLPR), stressful life events, and risk of depression: a meta-analysis. JAMA (2009) 12.35
Fruit and vegetable intake and risk of major chronic disease. J Natl Cancer Inst (2004) 8.77
Extended work shifts and the risk of motor vehicle crashes among interns. N Engl J Med (2005) 8.73
Common variation in three genes, including a noncoding variant in CFH, strongly influences risk of age-related macular degeneration. Nat Genet (2006) 7.49
Performance of common genetic variants in breast-cancer risk models. N Engl J Med (2010) 5.79
The effect of low-dose warfarin on the risk of stroke in patients with nonrheumatic atrial fibrillation. The Boston Area Anticoagulation Trial for Atrial Fibrillation Investigators. N Engl J Med (1990) 4.77
Toll-like receptor 3 and geographic atrophy in age-related macular degeneration. N Engl J Med (2008) 4.46
Genetic variants near TIMP3 and high-density lipoprotein-associated loci influence susceptibility to age-related macular degeneration. Proc Natl Acad Sci U S A (2010) 4.30
Moderate alcohol consumption during adult life, drinking patterns, and breast cancer risk. JAMA (2011) 4.25
Variation in complement factor 3 is associated with risk of age-related macular degeneration. Nat Genet (2007) 4.23
Frequency of analgesic use and risk of hypertension in younger women. Arch Intern Med (2002) 4.21
Mathematical multi-locus approaches to localizing complex human trait genes. Nat Rev Genet (2003) 4.18
Age-related macular degeneration. Lancet (2012) 4.17
The BRCA1-interacting helicase BRIP1 is deficient in Fanconi anemia. Nat Genet (2005) 4.13
Weight, weight gain, and survival after breast cancer diagnosis. J Clin Oncol (2005) 4.04
Comparison of risk factors for colon and rectal cancer. Int J Cancer (2004) 4.03
Seven new loci associated with age-related macular degeneration. Nat Genet (2013) 3.81
A rare penetrant mutation in CFH confers high risk of age-related macular degeneration. Nat Genet (2011) 3.55
A putative RUNX1 binding site variant between SLC9A3R1 and NAT9 is associated with susceptibility to psoriasis. Nat Genet (2003) 3.52
Relation between dieting and weight change among preadolescents and adolescents. Pediatrics (2003) 3.36
Distribution and characterization of regulatory elements in the human genome. Genome Res (2002) 3.34
Association of CFH Y402H and LOC387715 A69S with progression of age-related macular degeneration. JAMA (2007) 3.34
Genome-wide association study of advanced age-related macular degeneration identifies a role of the hepatic lipase gene (LIPC). Proc Natl Acad Sci U S A (2010) 3.33
Variation near complement factor I is associated with risk of advanced AMD. Eur J Hum Genet (2008) 3.29
Risk factors for the incidence of Advanced Age-Related Macular Degeneration in the Age-Related Eye Disease Study (AREDS) AREDS report no. 19. Ophthalmology (2005) 3.28
Extended work duration and the risk of self-reported percutaneous injuries in interns. JAMA (2006) 3.26
Impact of extended-duration shifts on medical errors, adverse events, and attentional failures. PLoS Med (2006) 3.22
Strong association of the Y402H variant in complement factor H at 1q32 with susceptibility to age-related macular degeneration. Am J Hum Genet (2005) 3.19
Potential public health impact of Age-Related Eye Disease Study results: AREDS report no. 11. Arch Ophthalmol (2003) 3.17
Restoring systemic GDF11 levels reverses age-related dysfunction in mouse skeletal muscle. Science (2014) 3.14
Adult weight change and risk of postmenopausal breast cancer. JAMA (2006) 3.11
The relationship of dietary carotenoid and vitamin A, E, and C intake with age-related macular degeneration in a case-control study: AREDS Report No. 22. Arch Ophthalmol (2007) 3.02
Comparison of risk factors for the competing risks of coronary heart disease, stroke, and venous thromboembolism. Am J Epidemiol (2005) 3.02
Age-related macular degeneration--a genome scan in extended families. Am J Hum Genet (2003) 2.99
Prediction model for prevalence and incidence of advanced age-related macular degeneration based on genetic, demographic, and environmental variables. Invest Ophthalmol Vis Sci (2008) 2.91
The association between complement component 2/complement factor B polymorphisms and age-related macular degeneration: a HuGE review and meta-analysis. Am J Epidemiol (2012) 2.87
Molecular genetic basis of inherited cataract and associated phenotypes. Surv Ophthalmol (2004) 2.85
Clinical trial of lutein in patients with retinitis pigmentosa receiving vitamin A. Arch Ophthalmol (2010) 2.78
Analysis of the ARMD1 locus: evidence that a mutation in HEMICENTIN-1 is associated with age-related macular degeneration in a large family. Hum Mol Genet (2003) 2.72
Relation between changes in intakes of dietary fiber and grain products and changes in weight and development of obesity among middle-aged women. Am J Clin Nutr (2003) 2.68
Serum lipids, lipid-lowering drugs, and the risk of breast cancer. Arch Intern Med (2005) 2.66
CpG island methylator phenotype associates with low-degree chromosomal abnormalities in colorectal cancer. Clin Cancer Res (2008) 2.65
Progression of age-related macular degeneration: association with dietary fat, transunsaturated fat, nuts, and fish intake. Arch Ophthalmol (2003) 2.50
Risk of new cancers after radiotherapy in long-term survivors of retinoblastoma: an extended follow-up. J Clin Oncol (2005) 2.37
The genetics of age-related macular degeneration: a review of progress to date. Surv Ophthalmol (2006) 2.37
Meta-analysis of genome scans of age-related macular degeneration. Hum Mol Genet (2005) 2.34
Risk of soft tissue sarcomas by individual subtype in survivors of hereditary retinoblastoma. J Natl Cancer Inst (2007) 2.32
Prospective study of the association of changes in dietary intake, physical activity, alcohol consumption, and smoking with 9-y gain in waist circumference among 16 587 US men. Am J Clin Nutr (2003) 2.29
Retinal toxicity associated with hydroxychloroquine and chloroquine: risk factors, screening, and progression despite cessation of therapy. Arch Ophthalmol (2011) 2.27
ω-3 intake and visual acuity in patients with retinitis pigmentosa receiving vitamin A. Arch Ophthalmol (2012) 2.23
Cigarette smoking, fish consumption, omega-3 fatty acid intake, and associations with age-related macular degeneration: the US Twin Study of Age-Related Macular Degeneration. Arch Ophthalmol (2006) 2.21
Progression of age-related macular degeneration: association with body mass index, waist circumference, and waist-hip ratio. Arch Ophthalmol (2003) 2.20
Physical activity and risk of breast cancer among postmenopausal women. Arch Intern Med (2010) 2.15
The relationship of dietary lipid intake and age-related macular degeneration in a case-control study: AREDS Report No. 20. Arch Ophthalmol (2007) 2.12
Epidemiology of urinary melatonin in women and its relation to other hormones and night work. Cancer Epidemiol Biomarkers Prev (2004) 2.10
Progression of age-related macular degeneration: prospective assessment of C-reactive protein, interleukin 6, and other cardiovascular biomarkers. Arch Ophthalmol (2005) 2.08
Desmoglein 4 in hair follicle differentiation and epidermal adhesion: evidence from inherited hypotrichosis and acquired pemphigus vulgaris. Cell (2003) 2.06
Lung cancer in railroad workers exposed to diesel exhaust. Environ Health Perspect (2004) 2.06
Genomic analysis defines a cancer-specific gene expression signature for human squamous cell carcinoma and distinguishes malignant hyperproliferation from benign hyperplasia. J Invest Dermatol (2006) 2.01
Correction of phenotype misclassification based on high-discrimination genetic predictive risk models. Epidemiology (2012) 2.01
Common variants near FRK/COL10A1 and VEGFA are associated with advanced age-related macular degeneration. Hum Mol Genet (2011) 1.98
Association of Fecundity With Changes in Adult Female Weight. Obstet Gynecol (2015) 1.97
The relationship of dietary omega-3 long-chain polyunsaturated fatty acid intake with incident age-related macular degeneration: AREDS report no. 23. Arch Ophthalmol (2008) 1.93
Healthful dietary patterns and type 2 diabetes mellitus risk among women with a history of gestational diabetes mellitus. Arch Intern Med (2012) 1.92
Lifetime nonnarcotic analgesic use and decline in renal function in women. Arch Intern Med (2004) 1.91
Functional impact of breast cancer by age at diagnosis. J Clin Oncol (2004) 1.91
Plasma complement components and activation fragments: associations with age-related macular degeneration genotypes and phenotypes. Invest Ophthalmol Vis Sci (2009) 1.86
Use of aspirin, other nonsteroidal anti-inflammatory drugs, and acetaminophen and postmenopausal breast cancer incidence. J Clin Oncol (2012) 1.85
Gestational vitamin D and the risk of multiple sclerosis in offspring. Ann Neurol (2011) 1.85
Dietary flavonoid intakes and risk of type 2 diabetes in US men and women. Am J Clin Nutr (2012) 1.84
Association of genetic loci: replication or not, that is the question. Neurology (2004) 1.84
Smoking, dietary betaine, methionine, and vitamin D in monozygotic twins with discordant macular degeneration: epigenetic implications. Ophthalmology (2011) 1.81
The validity of self-reported weight change among adolescents and young adults. Obesity (Silver Spring) (2007) 1.81
Further evaluation of docosahexaenoic acid in patients with retinitis pigmentosa receiving vitamin A treatment: subgroup analyses. Arch Ophthalmol (2004) 1.80
Body fatness during childhood and adolescence and incidence of breast cancer in premenopausal women: a prospective cohort study. Breast Cancer Res (2005) 1.77
Rare variants in CFI, C3 and C9 are associated with high risk of advanced age-related macular degeneration. Nat Genet (2013) 1.77
A prospective study of dietary flavonoid intake and incidence of epithelial ovarian cancer. Int J Cancer (2007) 1.76
Mammographic breast density and subsequent risk of breast cancer in postmenopausal women according to tumor characteristics. J Natl Cancer Inst (2011) 1.75
Risk assessment model for development of advanced age-related macular degeneration. Arch Ophthalmol (2011) 1.75
NHANES monitoring of serum 25-hydroxyvitamin D: a roundtable summary. J Nutr (2010) 1.74
Combined estrogen and testosterone use and risk of breast cancer in postmenopausal women. Arch Intern Med (2006) 1.74
Use of postmenopausal hormones, alcohol, and risk for invasive breast cancer. Ann Intern Med (2002) 1.73
Statins, fibrates, and ocular myasthenia. Lancet (2002) 1.71