Published in J Immunol on May 01, 2008
Infection with the intracellular bacterium, Listeria monocytogenes, overrides established tolerance in a mouse cardiac allograft model. Am J Transplant (2010) 1.68
Cutting edge: Rapamycin augments pathogen-specific but not graft-reactive CD8+ T cell responses. J Immunol (2010) 1.38
TLR signals promote IL-6/IL-17-dependent transplant rejection. J Immunol (2009) 1.26
Targeting co-stimulatory pathways: transplantation and autoimmunity. Nat Rev Nephrol (2013) 1.11
The impact of infection and tissue damage in solid-organ transplantation. Nat Rev Immunol (2012) 1.03
Permanent protection of PLG scaffold transplanted allogeneic islet grafts in diabetic mice treated with ECDI-fixed donor splenocyte infusions. Biomaterials (2011) 1.00
Limiting the amount and duration of antigen exposure during priming increases memory T cell requirement for costimulation during recall. J Immunol (2011) 0.97
Recent progress and new perspectives in studying T cell responses to allografts. Am J Transplant (2010) 0.96
IL-6 induced by Staphylococcus aureus infection prevents the induction of skin allograft acceptance in mice. Am J Transplant (2011) 0.96
TCR cross-reactivity and allorecognition: new insights into the immunogenetics of allorecognition. Immunogenetics (2011) 0.94
Donor-reactive T-cell stimulation history and precursor frequency: barriers to tolerance induction. Transplantation (2009) 0.91
Spontaneous restoration of transplantation tolerance after acute rejection. Nat Commun (2015) 0.91
Heterogeneity within T Cell Memory: Implications for Transplant Tolerance. Front Immunol (2012) 0.89
Disruption of murine cardiac allograft acceptance by latent cytomegalovirus. Am J Transplant (2008) 0.89
The composition of the microbiota modulates allograft rejection. J Clin Invest (2016) 0.88
Inflammation and transplantation tolerance. Semin Immunopathol (2011) 0.87
An anti-CD154 domain antibody prolongs graft survival and induces Foxp3(+) iTreg in the absence and presence of CTLA-4 Ig. Am J Transplant (2013) 0.87
Transplantation tolerance and its outcome during infections and inflammation. Immunol Rev (2014) 0.86
Toll-like receptor signaling in transplantation. Curr Opin Organ Transplant (2008) 0.86
Inflammatory triggers of acute rejection of organ allografts. Immunol Rev (2014) 0.86
Innate immunity and resistance to tolerogenesis in allotransplantation. Front Immunol (2012) 0.85
Bacterial infections, alloimmunity, and transplantation tolerance. Transplant Rev (Orlando) (2011) 0.85
The innate immune system in transplantation. Semin Immunol (2011) 0.84
Defining the alloreactive T cell repertoire using high-throughput sequencing of mixed lymphocyte reaction culture. PLoS One (2014) 0.84
Memory T cells in organ transplantation: progress and challenges. Nat Rev Nephrol (2016) 0.83
CpG oligodeoxynucleotide triggers the liver inflammatory reaction and abrogates spontaneous tolerance. Liver Transpl (2009) 0.81
Microbes and allogeneic transplantation. Transplantation (2014) 0.81
Alloreactive CD8 T cells rescued from apoptosis during co-stimulation blockade by Toll-like receptor stimulation remain susceptible to Fas-induced cell death. Immunology (2013) 0.80
Infectious pathogens may trigger specific allo-HLA reactivity via multiple mechanisms. Immunogenetics (2017) 0.79
The Microbiome, Systemic Immune Function, and Allotransplantation. Clin Microbiol Rev (2016) 0.79
Antagonistic effect of toll-like receptor signaling and bacterial infections on transplantation tolerance. Transplantation (2009) 0.78
T-cell activation and transplantation tolerance. Transplant Rev (Orlando) (2011) 0.78
The cholinergic anti-inflammatory pathway delays TLR-induced skin allograft rejection in mice: cholinergic pathway modulates alloreactivity. PLoS One (2013) 0.76
Micromanaging alloimmunity. J Clin Invest (2016) 0.75
Regulation of T cell alloimmunity by PI3Kγ and PI3Kδ. Nat Commun (2017) 0.75
Targeted disruption of the MyD88 gene results in loss of IL-1- and IL-18-mediated function. Immunity (1998) 18.12
Type I interferons in host defense. Immunity (2006) 7.32
Infection in organ-transplant recipients. N Engl J Med (1998) 6.49
Interferons, interferon-like cytokines, and their receptors. Immunol Rev (2004) 6.21
Primarily vascularized allografts of hearts in mice. The role of H-2D, H-2K, and non-H-2 antigens in rejection. Transplantation (1973) 6.01
Immune responses to Listeria monocytogenes. Nat Rev Immunol (2004) 5.91
Type I interferon in systemic lupus erythematosus and other autoimmune diseases. Immunity (2006) 5.47
Alloantigen-presenting plasmacytoid dendritic cells mediate tolerance to vascularized grafts. Nat Immunol (2006) 5.00
Accelerated CD8+ T-cell memory and prime-boost response after dendritic-cell vaccination. Nat Med (2005) 4.45
Heterologous immunity provides a potent barrier to transplantation tolerance. J Clin Invest (2003) 4.14
Cutting edge: TLR4 activation mediates liver ischemia/reperfusion inflammatory response via IFN regulatory factor 3-dependent MyD88-independent pathway. J Immunol (2004) 3.27
Recruitment of Foxp3+ T regulatory cells mediating allograft tolerance depends on the CCR4 chemokine receptor. J Exp Med (2005) 3.17
Combined TLR and CD40 triggering induces potent CD8+ T cell expansion with variable dependence on type I IFN. J Exp Med (2004) 2.89
Infections in solid-organ transplant recipients. Clin Microbiol Rev (1997) 2.86
Type I interferon-mediated stimulation of T cells by CpG DNA. J Exp Med (1998) 2.58
TLR engagement prevents transplantation tolerance. Am J Transplant (2006) 2.36
Sequential MyD88-independent and -dependent activation of innate immune responses to intracellular bacterial infection. Immunity (2003) 2.20
Primed allospecific T cells prevent the effects of costimulatory blockade on prolonged cardiac allograft survival in mice. Am J Transplant (2002) 2.18
CD8alpha+ dendritic cells selectively present MHC class I-restricted noncytolytic viral and intracellular bacterial antigens in vivo. J Immunol (2005) 2.16
Heterologous immunity: an overlooked barrier to tolerance. Immunol Rev (2003) 1.76
T cells primed by Leishmania major infection cross-react with alloantigens and alter the course of allograft rejection. J Immunol (2002) 1.73
The significance of alpha/beta interferons and gamma interferon produced in mice infected with Listeria monocytogenes. Cell Immunol (1984) 1.67
Virus-induced abrogation of transplantation tolerance induced by donor-specific transfusion and anti-CD154 antibody. J Virol (2000) 1.64
Late-acute renal allograft rejection and symptomless cytomegalovirus infection. Lancet (1995) 1.63
Direct visualization of cross-reactive effector and memory allo-specific CD8 T cells generated in response to viral infections. J Immunol (2003) 1.61
IL-12 and type-I IFN synergize for IFN-gamma production by CD4 T cells, whereas neither are required for IFN-gamma production by CD8 T cells after Listeria monocytogenes infection. J Immunol (2007) 1.58
TLR agonists abrogate costimulation blockade-induced prolongation of skin allografts. J Immunol (2006) 1.57
Cutting edge: persistent viral infection prevents tolerance induction and escapes immune control following CD28/CD40 blockade-based regimen. J Immunol (2002) 1.55
Characterization of virus-mediated inhibition of mixed chimerism and allospecific tolerance. J Immunol (2001) 1.49
Prevention of infections in solid organ transplant recipients. Transpl Infect Dis (1999) 1.41
Immune activation of type I IFNs by Listeria monocytogenes occurs independently of TLR4, TLR2, and receptor interacting protein 2 but involves TNFR-associated NF kappa B kinase-binding kinase 1. J Immunol (2005) 1.38
The impact of cytomegalovirus infection and disease on rejection episodes in renal allograft recipients. Am J Transplant (2002) 1.36
Type 1 IFN mediates cross-talk between innate and adaptive immunity that abrogates transplantation tolerance. J Immunol (2007) 1.34
Absence of innate MyD88 signaling promotes inducible allograft acceptance. J Immunol (2006) 1.33
Major complications following hematopoietic stem cell transplantation. Semin Respir Crit Care Med (2006) 1.32
IFN-alpha beta promote priming of antigen-specific CD8+ and CD4+ T lymphocytes by immunostimulatory DNA-based vaccines. J Immunol (2002) 1.30
A compass that points to lupus: genetic studies on type I interferon pathway. Genes Immun (2007) 1.24
Listeria-infected myeloid dendritic cells produce IFN-beta, priming T cell activation. J Immunol (2005) 1.16
Signal 3 availability limits the CD8 T cell response to a solid tumor. J Immunol (2007) 1.16
Heme oxygenase-1 mediated cytoprotection against liver ischemia and reperfusion injury: inhibition of type-1 interferon signaling. Transplantation (2007) 1.12
New aspects of IFN-alpha/beta signalling in immunity, oncogenesis and bone metabolism. Cancer Sci (2003) 1.01
The interferon response to bacterial and viral infections. J Endotoxin Res (2006) 1.00
IFN beta accelerates autoimmune type 1 diabetes in nonobese diabetic mice and breaks the tolerance to beta cells in nondiabetes-prone mice. J Immunol (2004) 1.00
Different mechanisms of cardiac allograft rejection in wildtype and CD28-deficient mice. Am J Transplant (2001) 0.96
Parainfluenza virus infection in adult lung transplant recipients: an emergent clinical syndrome with implications on allograft function. Am J Transplant (2003) 0.93
Costimulatory molecules as targets for the induction of transplantation tolerance. Curr Mol Med (2006) 0.92
Protective T cell response against intracellular pathogens in the absence of Toll-like receptor signaling via myeloid differentiation factor 88. Int Immunol (2004) 0.89
Consequences of cross-reactive and bystander CTL responses during viral infections. Virology (2000) 0.87
Interferon-beta1a for the treatment of multiple sclerosis. Expert Opin Biol Ther (2007) 0.87
Cytomegalovirus seromismatching increases the risk of acute renal allograft rejection. Transplantation (2002) 0.85
Epidemiology of bloodstream infections in the first year after pediatric lung transplantation. Pediatr Infect Dis J (2005) 0.83
Acute renal allograft rejection following pegylated IFN-alpha treatment for chronic HCV in a repeat allograft recipient on hemodialysis: a case report. Am J Transplant (2006) 0.82
Alloimmunity: no toll exemption. Am J Transplant (2007) 0.77
The clinical and immunologic impact of using interferon and ribavirin in the immunosuppressed host. Liver Transpl (2003) 0.77
Treatment of acute hepatitis C. Curr Pharm Des (2004) 0.77
Modulation of tryptophan catabolism by regulatory T cells. Nat Immunol (2003) 5.47
Mitochondria are required for antigen-specific T cell activation through reactive oxygen species signaling. Immunity (2013) 4.08
IL-1 mediates TNF-induced osteoclastogenesis. J Clin Invest (2005) 3.56
Targeted reinnervation for enhanced prosthetic arm function in a woman with a proximal amputation: a case study. Lancet (2007) 3.54
Exaggerated inflammation, impaired host defense, and neuropathology in progranulin-deficient mice. J Exp Med (2009) 3.32
GATA-3: an unexpected regulator of cell lineage determination in skin. Genes Dev (2003) 2.97
Prostaglandin E2 EP1 receptors: downstream effectors of COX-2 neurotoxicity. Nat Med (2006) 2.94
Glycolipid antigen induces long-term natural killer T cell anergy in mice. J Clin Invest (2005) 2.85
Directing mesenchymal stem cells to bone to augment bone formation and increase bone mass. Nat Med (2012) 2.80
The response of natural killer T cells to glycolipid antigens is characterized by surface receptor down-modulation and expansion. Proc Natl Acad Sci U S A (2003) 2.62
Targeting the NF-kappaB signaling pathway in Notch1-induced T-cell leukemia. Nat Med (2006) 2.35
Nox2-derived radicals contribute to neurovascular and behavioral dysfunction in mice overexpressing the amyloid precursor protein. Proc Natl Acad Sci U S A (2008) 2.27
An analysis of EMG electrode configuration for targeted muscle reinnervation based neural machine interface. IEEE Trans Neural Syst Rehabil Eng (2008) 1.96
The endoplasmic reticulum enzyme DGAT2 is found in mitochondria-associated membranes and has a mitochondrial targeting signal that promotes its association with mitochondria. J Biol Chem (2008) 1.94
Reversal of diabetes in non-obese diabetic mice without spleen cell-derived beta cell regeneration. Science (2006) 1.88
A comprehensive analysis of the dual roles of BMPs in regulating adipogenic and osteogenic differentiation of mesenchymal progenitor cells. Stem Cells Dev (2009) 1.87
Pyridone 6, a pan-Janus-activated kinase inhibitor, induces growth inhibition of multiple myeloma cells. Cancer Res (2006) 1.80
Nox2-derived reactive oxygen species mediate neurovascular dysregulation in the aging mouse brain. J Cereb Blood Flow Metab (2007) 1.79
MyD88-5 links mitochondria, microtubules, and JNK3 in neurons and regulates neuronal survival. J Exp Med (2007) 1.74
Identification of a gene encoding MGAT1, a monoacylglycerol acyltransferase. Proc Natl Acad Sci U S A (2002) 1.74
Angiotensin II impairs neurovascular coupling in neocortex through NADPH oxidase-derived radicals. Circ Res (2004) 1.74
Mining and characterizing microsatellites from citrus ESTs. Theor Appl Genet (2006) 1.74
Quantitative and qualitative differences in the in vivo response of NKT cells to distinct alpha- and beta-anomeric glycolipids. J Immunol (2004) 1.73
Local expression of B7-H1 promotes organ-specific autoimmunity and transplant rejection. J Clin Invest (2004) 1.71
Seeking confidence in the diagnosis of systemic AL (Ig light-chain) amyloidosis: patients can have both monoclonal gammopathies and hereditary amyloid proteins. Blood (2006) 1.70
NADPH-oxidase-derived reactive oxygen species mediate the cerebrovascular dysfunction induced by the amyloid beta peptide. J Neurosci (2005) 1.68
Deficiency of the intestinal enzyme acyl CoA:monoacylglycerol acyltransferase-2 protects mice from metabolic disorders induced by high-fat feeding. Nat Med (2009) 1.68
A transcriptomic analysis of superhybrid rice LYP9 and its parents. Proc Natl Acad Sci U S A (2009) 1.67
Teager-Kaiser energy operation of surface EMG improves muscle activity onset detection. Ann Biomed Eng (2007) 1.66
Genetic variants in STAT4 and HLA-DQ genes confer risk of hepatitis B virus-related hepatocellular carcinoma. Nat Genet (2012) 1.64
M-CSF mediates TNF-induced inflammatory osteolysis. J Clin Invest (2005) 1.64
CD1d-expressing dendritic cells but not thymic epithelial cells can mediate negative selection of NKT cells. J Exp Med (2003) 1.63
Pedicle screw insertion accuracy with different assisted methods: a systematic review and meta-analysis of comparative studies. Eur Spine J (2010) 1.60
Maintaining the self-renewal and differentiation potential of human CD34+ hematopoietic cells using a single genetic element. Blood (2003) 1.59
Insulin-like growth factor 2 (IGF-2) potentiates BMP-9-induced osteogenic differentiation and bone formation. J Bone Miner Res (2010) 1.58
Glycemic control promotes pancreatic beta-cell regeneration in streptozotocin-induced diabetic mice. PLoS One (2010) 1.58
Shikonin exerts antitumor activity via proteasome inhibition and cell death induction in vitro and in vivo. Int J Cancer (2009) 1.55
BMP-9-induced osteogenic differentiation of mesenchymal progenitors requires functional canonical Wnt/beta-catenin signalling. J Cell Mol Med (2008) 1.54
NMDA receptor activation increases free radical production through nitric oxide and NOX2. J Neurosci (2009) 1.54
Transcriptional regulation of germinal center B and plasma cell fates by dynamical control of IRF4. Immunity (2013) 1.52
Marrow stromal cells and osteoclast precursors differentially contribute to TNF-alpha-induced osteoclastogenesis in vivo. J Immunol (2004) 1.50
Angiotensin II attenuates endothelium-dependent responses in the cerebral microcirculation through nox-2-derived radicals. Arterioscler Thromb Vasc Biol (2006) 1.50
Hey1 basic helix-loop-helix protein plays an important role in mediating BMP9-induced osteogenic differentiation of mesenchymal progenitor cells. J Biol Chem (2008) 1.48
Ecto-5'-nucleotidase promotes invasion, migration and adhesion of human breast cancer cells. J Cancer Res Clin Oncol (2007) 1.47
Nuclear factor-kappaB activation and postischemic inflammation are suppressed in CD36-null mice after middle cerebral artery occlusion. J Neurosci (2008) 1.46
Selective inhibition of anthrax edema factor by adefovir, a drug for chronic hepatitis B virus infection. Proc Natl Acad Sci U S A (2004) 1.46
A triterpene glycoside from black cohosh that inhibits osteoclastogenesis by modulating RANKL and TNFalpha signaling pathways. Chem Biol (2007) 1.44
Retracted Meta-analysis of the efficacy of pancreatoduodenectomy with extended lymphadenectomy in the treatment of pancreatic cancer. World J Surg Oncol (2013) 1.44
Nox2, Ca2+, and protein kinase C play a role in angiotensin II-induced free radical production in nucleus tractus solitarius. Hypertension (2006) 1.44
Physiological levels of ATP negatively regulate proteasome function. Cell Res (2010) 1.44
Serine protease inhibitor 6 protects cytotoxic T cells from self-inflicted injury by ensuring the integrity of cytotoxic granules. Immunity (2006) 1.43
Retracted Pharmacologic inactivation of kinase suppressor of Ras1 sensitizes epidermal growth factor receptor and oncogenic Ras-dependent tumors to ionizing radiation treatment. Mol Cancer Ther (2010) 1.43
CD1-restricted adaptive immune responses to Mycobacteria in human group 1 CD1 transgenic mice. J Exp Med (2009) 1.43
Neurovascular protection by ischemic tolerance: role of nitric oxide and reactive oxygen species. J Neurosci (2007) 1.42
Chronic hepatitis virus infection increases the risk of pancreatic cancer: a meta-analysis. Hepatobiliary Pancreat Dis Int (2013) 1.42
TGFbeta/BMP type I receptors ALK1 and ALK2 are essential for BMP9-induced osteogenic signaling in mesenchymal stem cells. J Biol Chem (2010) 1.40
Tetrandrine inhibits Wnt/β-catenin signaling and suppresses tumor growth of human colorectal cancer. Mol Pharmacol (2010) 1.40
CARMA1 controls an early checkpoint in the thymic development of FoxP3+ regulatory T cells. J Immunol (2009) 1.40
Current evidence on the relationship between HRAS1 polymorphism and breast cancer risk: a meta-analysis. Breast Cancer Res Treat (2011) 1.39
Cerebrovascular nitrosative stress mediates neurovascular and endothelial dysfunction induced by angiotensin II. Arterioscler Thromb Vasc Biol (2006) 1.35
Dissociation of obesity and impaired glucose disposal in mice overexpressing acyl coenzyme a:diacylglycerol acyltransferase 1 in white adipose tissue. Diabetes (2002) 1.34
Progranulin deficiency promotes neuroinflammation and neuron loss following toxin-induced injury. J Clin Invest (2012) 1.34
Cyclooxygenase-2 does not contribute to postischemic production of reactive oxygen species. J Cereb Blood Flow Metab (2006) 1.34
Functional genomic analyses identify pathways dysregulated by progranulin deficiency, implicating Wnt signaling. Neuron (2011) 1.34
Specific role for acyl CoA:Diacylglycerol acyltransferase 1 (Dgat1) in hepatic steatosis due to exogenous fatty acids. Hepatology (2009) 1.32
T-cell receptor-induced NF-kappaB activation is negatively regulated by E3 ubiquitin ligase Cbl-b. Mol Cell Biol (2008) 1.30
Widespread nonhematopoietic tissue distribution by transplanted human progenitor cells with high aldehyde dehydrogenase activity. Stem Cells (2007) 1.30
Repeated alpha-galactosylceramide administration results in expansion of NK T cells and alleviates inflammatory dermatitis in MRL-lpr/lpr mice. J Immunol (2003) 1.29
RNA interference of ecto-5'-nucleotidase (CD73) inhibits human breast cancer cell growth and invasion. Clin Exp Metastasis (2007) 1.29
Modified anti-CD3 therapy in psoriatic arthritis: a phase I/II clinical trial. J Rheumatol (2002) 1.28
A neurodegenerative disease mutation that accelerates the clearance of apoptotic cells. Proc Natl Acad Sci U S A (2011) 1.28
TLR signals promote IL-6/IL-17-dependent transplant rejection. J Immunol (2009) 1.26
Obligatory role of inducible nitric oxide synthase in ischemic preconditioning. J Cereb Blood Flow Metab (2005) 1.24
Prostanoids, not reactive oxygen species, mediate COX-2-dependent neurotoxicity. Ann Neurol (2004) 1.24
Establishment and characterization of a new highly metastatic human osteosarcoma cell line. Clin Exp Metastasis (2009) 1.23
Synergistic antitumor effect of the activated PPARgamma and retinoid receptors on human osteosarcoma. Clin Cancer Res (2010) 1.22
Key role of CD36 in Toll-like receptor 2 signaling in cerebral ischemia. Stroke (2010) 1.21
Innate immunity receptor CD36 promotes cerebral amyloid angiopathy. Proc Natl Acad Sci U S A (2013) 1.21
Impaired response to Listeria in H2-M3-deficient mice reveals a nonredundant role of MHC class Ib-specific T cells in host defense. J Exp Med (2006) 1.20
Essential role of TNF family molecule LIGHT as a cytokine in the pathogenesis of hepatitis. J Clin Invest (2006) 1.20
The natural killer T cell ligand alpha-galactosylceramide prevents or promotes pristane-induced lupus in mice. Eur J Immunol (2005) 1.20
Risk-adapted autologous stem cell transplantation with adjuvant dexamethasone +/- thalidomide for systemic light-chain amyloidosis: results of a phase II trial. Br J Haematol (2007) 1.20
Recovery of islet beta-cell function in streptozotocin- induced diabetic mice: an indirect role for the spleen. Diabetes (2006) 1.19
Scavenger receptor CD36 is essential for the cerebrovascular oxidative stress and neurovascular dysfunction induced by amyloid-beta. Proc Natl Acad Sci U S A (2011) 1.19
CD1d deficiency exacerbates inflammatory dermatitis in MRL-lpr/lpr mice. Eur J Immunol (2004) 1.18
Ginsenoside Rg3 inhibits colorectal tumor growth through the down-regulation of Wnt/ß-catenin signaling. Int J Oncol (2010) 1.18
Mast cell-dependent control of Giardia lamblia infections in mice. Infect Immun (2004) 1.18
Actin cytoskeleton regulates calcium dynamics and NFAT nuclear duration. Mol Cell Biol (2004) 1.18
Evidence that estrogen directly and indirectly modulates C1 adrenergic bulbospinal neurons in the rostral ventrolateral medulla. Brain Res (2006) 1.18
Retinoic acids potentiate BMP9-induced osteogenic differentiation of mesenchymal progenitor cells. PLoS One (2010) 1.17
Retinol Esterification by DGAT1 Is Essential for Retinoid Homeostasis in Murine Skin. J Biol Chem (2008) 1.17