Published in Cell Calcium on April 25, 2008
Presenilins and γ-secretase: structure, function, and role in Alzheimer Disease. Cold Spring Harb Perspect Med (2012) 2.02
Role of presenilins in neuronal calcium homeostasis. J Neurosci (2010) 1.59
Ryanodine receptor blockade reduces amyloid-β load and memory impairments in Tg2576 mouse model of Alzheimer disease. J Neurosci (2012) 1.16
Presenilin-2 dampens intracellular Ca2+ stores by increasing Ca2+ leakage and reducing Ca2+ uptake. J Cell Mol Med (2009) 1.01
Susceptibility to Calcium Dysregulation during Brain Aging. Front Aging Neurosci (2009) 0.91
Intracellular calcium signalling in Alzheimer's disease. J Cell Mol Med (2009) 0.91
Control of intracellular calcium signaling as a neuroprotective strategy. Molecules (2010) 0.89
Presenilins regulate the cellular activity of ryanodine receptors differentially through isotype-specific N-terminal cysteines. Exp Neurol (2013) 0.87
Ryanodine receptors: physiological function and deregulation in Alzheimer disease. Mol Neurodegener (2014) 0.82
The γ-secretase complex: from structure to function. Front Cell Neurosci (2014) 0.81
Loss of Spatial Memory, Learning, and Motor Function During Normal Aging Is Accompanied by Changes in Brain Presenilin 1 and 2 Expression Levels. Mol Neurobiol (2014) 0.81
Involvement of presenilin holoprotein upregulation in calcium dyshomeostasis of Alzheimer's disease. J Cell Mol Med (2013) 0.80
Intracellular calcium deficits in Drosophila cholinergic neurons expressing wild type or FAD-mutant presenilin. PLoS One (2009) 0.80
Distribution and function of polycystin-2 in mouse retinal ganglion cells. Neuroscience (2011) 0.80
The unliganded long isoform of estrogen receptor beta stimulates brain ryanodine receptor single channel activity alongside with cytosolic Ca2+. J Recept Signal Transduct Res (2009) 0.79
Dantrolene, a treatment for Alzheimer disease? Alzheimer Dis Assoc Disord (2015) 0.79
Regulation of ryanodine receptor-mediated calcium signaling by presenilins. Receptors Clin Investig (2015) 0.76
Emerging pathways driving early synaptic pathology in Alzheimer's disease. Biochem Biophys Res Commun (2016) 0.76
KChIP2 regulates the cardiac Ca2+ transient and myocyte contractility by targeting ryanodine receptor activity. PLoS One (2017) 0.75
Dysregulation of neuronal calcium homeostasis in Alzheimer's disease - A therapeutic opportunity? Biochem Biophys Res Commun (2016) 0.75
Mitochondrial localization of estrogen receptor beta. Proc Natl Acad Sci U S A (2004) 2.15
Estrogen attenuates nuclear factor-kappa B activation induced by transient cerebral ischemia. Brain Res (2004) 1.29
Distinct intracellular calcium transients in neurites and somata integrate neuronal signals. J Neurosci (2002) 1.24
Proteolytic cleavage and nuclear translocation of fibrocystin is regulated by intracellular Ca2+ and activation of protein kinase C. J Biol Chem (2006) 1.22
Cdk5 is involved in NFT-like tauopathy induced by transient cerebral ischemia in female rats. Biochim Biophys Acta (2006) 1.20
The neuroprotective properties of palmitoylethanolamine against oxidative stress in a neuronal cell line. Mol Neurodegener (2009) 1.16
Human and yeast Rad52 proteins promote DNA strand exchange. Proc Natl Acad Sci U S A (2004) 1.10
Effects of Vesl/Homer proteins on intracellular signaling. Exp Biol Med (Maywood) (2005) 1.09
Transient cerebral ischemia induces aberrant neuronal cell cycle re-entry and Alzheimer's disease-like tauopathy in female rats. J Biol Chem (2004) 1.07
The C terminus of Bax inhibitor-1 forms a Ca2+-permeable channel pore. J Biol Chem (2011) 1.07
The cytosolic N-terminus of presenilin-1 potentiates mouse ryanodine receptor single channel activity. Int J Biochem Cell Biol (2007) 1.05
Estrogen protects the inner retina from apoptosis and ischemia-induced loss of Vesl-1L/Homer 1c immunoreactive synaptic connections. Invest Ophthalmol Vis Sci (2003) 1.05
Leaky sodium channels from voltage sensor mutations in periodic paralysis, but not paramyotonia. Neurology (2011) 1.04
Vesl/Homer proteins regulate ryanodine receptor type 2 function and intracellular calcium signaling. Cell Calcium (2003) 1.02
Lipid profiling reveals tissue-specific differences for ethanolamide lipids in mice lacking fatty acid amide hydrolase. Lipids (2010) 1.00
Differential functional interaction of two Vesl/Homer protein isoforms with ryanodine receptor type 1: a novel mechanism for control of intracellular calcium signaling. Cell Calcium (2003) 1.00
Quantification of deficits in spatial visual function of mouse models for glaucoma. Invest Ophthalmol Vis Sci (2011) 0.97
Plate reader-based assays for measuring cell viability, neuroprotection and calcium in primary neuronal cultures. J Neurosci Methods (2011) 0.95
Progesterone increases the release of brain-derived neurotrophic factor from glia via progesterone receptor membrane component 1 (Pgrmc1)-dependent ERK5 signaling. Endocrinology (2012) 0.94
Proteomic analysis of mouse brain microsomes: identification and bioinformatic characterization of endoplasmic reticulum proteins in the mammalian central nervous system. J Proteome Res (2008) 0.94
The intracellular Ca²⁺ channels of membrane traffic. Channels (Austin) (2012) 0.93
A novel organotypic culture model of the postnatal mouse retina allows the study of glutamate-mediated excitotoxicity. J Neurosci Methods (2006) 0.92
Effects of dilution and prolonged storage with preservative in a polyethylene container on Bevacizumab (Avastin™) for topical delivery as a nasal spray in anti-hereditary hemorrhagic telangiectasia and related therapies. Hum Antibodies (2011) 0.91
17β-estradiol eye drops protect the retinal ganglion cell layer and preserve visual function in an in vivo model of glaucoma. Mol Pharm (2013) 0.91
Control of intracellular calcium signaling as a neuroprotective strategy. Molecules (2010) 0.89
Progesterone potentiates calcium release through IP3 receptors by an Akt-mediated mechanism in hippocampal neurons. Cell Calcium (2008) 0.89
Lauroylethanolamide and linoleoylethanolamide improve functional outcome in a rodent model for stroke. Neurosci Lett (2011) 0.88
Differential inositol 1,4,5-trisphosphate receptor signaling in a neuronal cell line. Int J Biochem Cell Biol (2007) 0.87
Identification of a beta-dystroglycan immunoreactive subcompartment in photoreceptor terminals. Invest Ophthalmol Vis Sci (2006) 0.87
Presenilins regulate the cellular activity of ryanodine receptors differentially through isotype-specific N-terminal cysteines. Exp Neurol (2013) 0.87
Protection of neurons in the retinal ganglion cell layer against excitotoxicity by the N-acylethanolamine, N-linoleoylethanolamine. Clin Ophthalmol (2011) 0.84
Detection of novel biomarkers for ovarian cancer with an optical nanotechnology detection system enabling label-free diagnostics. J Biomed Opt (2012) 0.84
Polycystin-1 can interact with homer 1/Vesl-1 in postnatal hippocampal neurons. J Neurosci Res (2006) 0.83
Localization of inositol 1,4,5-trisphosphate receptors in mouse retinal ganglion cells. J Neurosci Res (2006) 0.82
ERK1/2 and ERK5 have distinct roles in the regulation of brain-derived neurotrophic factor expression. J Neurosci Res (2011) 0.82
Ca2+-sensitive transcriptional regulation: direct DNA interaction by DREAM. Front Biosci (Landmark Ed) (2009) 0.81
Homer-1a immediate early gene expression correlates with better cognitive performance in aging. Age (Dordr) (2012) 0.81
Loss of Spatial Memory, Learning, and Motor Function During Normal Aging Is Accompanied by Changes in Brain Presenilin 1 and 2 Expression Levels. Mol Neurobiol (2014) 0.81
A case for neuroprotection in ophthalmology: developments in translational research. Mo Med (2013) 0.80
Activation of aerobic metabolism by Amaranth oil improves heart rate variability both in athletes and patients with type 2 diabetes mellitus. Arch Physiol Biochem (2012) 0.80
Regulator of G-protein signaling 14 protein modulates Ca²+ influx through Cav1 channels. Neuroreport (2010) 0.80
N-Palmitoylethanolamine depot injection increased its tissue levels and those of other acylethanolamide lipids. Drug Des Devel Ther (2013) 0.80
Development of glutamatergic synapses in the rat retina: the postnatal expression of ionotropic glutamate receptor subunits. Vis Neurosci (2002) 0.79
ERK5/KLF4 signaling as a common mediator of the neuroprotective effects of both nerve growth factor and hydrogen peroxide preconditioning. Age (Dordr) (2014) 0.79
The unliganded long isoform of estrogen receptor beta stimulates brain ryanodine receptor single channel activity alongside with cytosolic Ca2+. J Recept Signal Transduct Res (2009) 0.79
On the temperature and tension dependence of the outer hair cell lateral membrane conductance GmetL and its relation to prestin. Pflugers Arch (2006) 0.79
Polycystin-2 expression and function in adult mouse lacrimal acinar cells. Invest Ophthalmol Vis Sci (2011) 0.78
Microfluorimetry defines early axonal damage in a rat model of optic neuritis: a novel method targeting early CNS autoimmunity. J Neurosci Methods (2007) 0.78
Homer proteins control neuronal differentiation through IP(3) receptor signaling. FEBS Lett (2006) 0.78
Comparative study of membranotropic action of single- and multi-walled carbon nanotubes. J Biosci Bioeng (2013) 0.77
Synthesis of phenoxyacyl-ethanolamides and their effects on fatty acid amide hydrolase activity. J Biol Chem (2014) 0.77
Transient 5-(4-phenylbutoxy)psoralen (PAP-1) treatment dissociates developing pathologies in autoimmune optic neuritis into two distinct pathology profiles. J Neurosci Res (2008) 0.76
Cell Models for the Study of Sex Steroid Hormone Neurobiology. J Steroids Horm Sci (2012) 0.76
Role of a Galphai2 protein splice variant in the formation of an intracellular dopamine D2 receptor pool. J Cell Sci (2007) 0.76
Comparing the efficacy of the monocular trial treatment paradigm with multiple measurements of intraocular pressure before and after treatment initiation in primary open-angle glaucoma. Clin Ophthalmol (2012) 0.75
Evaluation of tensile strength of tissue adhesives and sutures for clear corneal incisions using porcine and bovine eyes, with a novel standardized testing platform. Clin Ophthalmol (2012) 0.75