Published in Cancer Lett on June 08, 2008
Anti-cancer natural products isolated from chinese medicinal herbs. Chin Med (2011) 1.39
β-Elemene-induced autophagy protects human gastric cancer cells from undergoing apoptosis. BMC Cancer (2011) 1.21
Downregulated miR-646 in clear cell renal carcinoma correlated with tumour metastasis by targeting the nin one binding protein (NOB1). Br J Cancer (2014) 1.08
β-elemene inhibited expression of DNA methyltransferase 1 through activation of ERK1/2 and AMPKα signalling pathways in human lung cancer cells: the role of Sp1. J Cell Mol Med (2015) 1.00
MicroRNA-326 functions as a tumor suppressor in glioma by targeting the Nin one binding protein (NOB1). PLoS One (2013) 0.93
Sunlight UV-induced skin cancer relies upon activation of the p38α signaling pathway. Cancer Res (2013) 0.93
Preparation and characterization of solid lipid nanoparticles loaded with frankincense and myrrh oil. Int J Nanomedicine (2012) 0.92
Beta-elemene blocks epithelial-mesenchymal transition in human breast cancer cell line MCF-7 through Smad3-mediated down-regulation of nuclear transcription factors. PLoS One (2013) 0.88
p38γ overexpression in gliomas and its role in proliferation and apoptosis. Sci Rep (2013) 0.84
Antiproliferative and apoptotic effects of β-elemene on human hepatoma HepG2 cells. Cancer Cell Int (2013) 0.83
β -Elemene-Attenuated Tumor Angiogenesis by Targeting Notch-1 in Gastric Cancer Stem-Like Cells. Evid Based Complement Alternat Med (2013) 0.82
HIF-1α induced by β-elemene protects human osteosarcoma cells from undergoing apoptosis. J Cancer Res Clin Oncol (2012) 0.78
The effects of β-elemene on the expression of mTOR, HIF-1A, survivin in lung adenocarcinoma A549 cell. Afr J Tradit Complement Altern Med (2013) 0.77
β-elemene sensitizes hepatocellular carcinoma cells to oxaliplatin by preventing oxaliplatin-induced degradation of copper transporter 1. Sci Rep (2016) 0.76
Effect of Centella asiatica Leaf Extract on the Dietary Supplementation in Transgenic Drosophila Model of Parkinson's Disease. Parkinsons Dis (2014) 0.75
Elemene Induces Apoptosis of Human Gastric Cancer Cell Line BGC-823 via Extracellular Signal-Regulated Kinase (ERK) 1/2 Signaling Pathway. Med Sci Monit (2017) 0.75
Enhancing effect of β-elemene emulsion on chemotherapy with harringtonine, aclacinomycin, and Ara-c in treatment of refractory/relapsed acute myeloid leukemia. Pak J Med Sci (2015) 0.75
Development of Certain Protein Kinase Inhibitors with the Components from Traditional Chinese Medicine. Front Pharmacol (2017) 0.75
β-Elemene: Mechanistic Studies on Cancer Cell Interaction and Its Chemosensitization Effect. Front Pharmacol (2017) 0.75
Composition and cytotoxic and antioxidant activities of the oil of Piper aequale Vahl. Lipids Health Dis (2016) 0.75
Protective Effect of Piper aduncum Capsule on DMBA-induced Breast Cancer in Rats. Breast Cancer (Auckl) (2015) 0.75
β-Elemene treatment of glioblastoma: a single-center retrospective study. Onco Targets Ther (2016) 0.75
Reversion of malignant phenotypes of human glioblastoma cells by β-elemene through β-catenin-mediated regulation of stemness-, differentiation- and epithelial-to-mesenchymal transition-related molecules. J Transl Med (2015) 0.75
Identification of a novel hedycaryol synthase gene isolated from Camellia brevistyla flowers and floral scent of Camellia cultivars. Planta (2016) 0.75
Improving In Vivo Efficacy of Bioactive Molecules: An Overview of Potentially Antitumor Phytochemicals and Currently Available Lipid-Based Delivery Systems. J Oncol (2017) 0.75
Essential role of TRPC channels in the guidance of nerve growth cones by brain-derived neurotrophic factor. Nature (2005) 2.78
Internalization of NK cells into tumor cells requires ezrin and leads to programmed cell-in-cell death. Cell Res (2009) 2.07
Construction of a high-density genetic map for sesame based on large scale marker development by specific length amplified fragment (SLAF) sequencing. BMC Plant Biol (2013) 1.84
Phosphorylation of human Sgo1 by NEK2A is essential for chromosome congression in mitosis. Cell Res (2007) 1.71
Human Zwint-1 specifies localization of Zeste White 10 to kinetochores and is essential for mitotic checkpoint signaling. J Biol Chem (2004) 1.44
Aurora B kinase activation requires survivin priming phosphorylation by PLK1. J Mol Cell Biol (2010) 1.43
Stabilization of PML nuclear localization by conjugation and oligomerization of SUMO-3. Oncogene (2005) 1.33
Phosphorylation of HsMis13 by Aurora B kinase is essential for assembly of functional kinetochore. J Biol Chem (2008) 1.30
Simultaneous determination of six active components in crude and processed Fructus Corni by high performance liquid chromatography. J Pharm Biomed Anal (2008) 1.28
Human NUF2 interacts with centromere-associated protein E and is essential for a stable spindle microtubule-kinetochore attachment. J Biol Chem (2007) 1.27
PLK1 phosphorylates mitotic centromere-associated kinesin and promotes its depolymerase activity. J Biol Chem (2010) 1.24
Septin 7 interacts with centromere-associated protein E and is required for its kinetochore localization. J Biol Chem (2008) 1.21
DNA methylation-regulated miR-193a-3p dictates resistance of hepatocellular carcinoma to 5-fluorouracil via repression of SRSF2 expression. J Biol Chem (2011) 1.19
PALS1 specifies the localization of ezrin to the apical membrane of gastric parietal cells. J Biol Chem (2005) 1.15
PKA-mediated protein phosphorylation regulates ezrin-WWOX interaction. Biochem Biophys Res Commun (2006) 1.14
CENP-E kinesin interacts with SKAP protein to orchestrate accurate chromosome segregation in mitosis. J Biol Chem (2011) 1.12
Rho kinase phosphorylation promotes ezrin-mediated metastasis in hepatocellular carcinoma. Cancer Res (2011) 1.11
EB1 acetylation by P300/CBP-associated factor (PCAF) ensures accurate kinetochore-microtubule interactions in mitosis. Proc Natl Acad Sci U S A (2012) 1.09
PRC1 cooperates with CLASP1 to organize central spindle plasticity in mitosis. J Biol Chem (2009) 1.06
Mitotic regulator SKAP forms a link between kinetochore core complex KMN and dynamic spindle microtubules. J Biol Chem (2012) 1.05
Proteomic identification and functional characterization of a novel ARF6 GTPase-activating protein, ACAP4. Mol Cell Proteomics (2006) 1.05
Blockade of TRPC6 channels induced G2/M phase arrest and suppressed growth in human gastric cancer cells. Int J Cancer (2009) 1.04
Helicobacter pylori VacA disrupts apical membrane-cytoskeletal interactions in gastric parietal cells. J Biol Chem (2008) 1.04
Phosphorylation of microtubule-binding protein Hec1 by mitotic kinase Aurora B specifies spindle checkpoint kinase Mps1 signaling at the kinetochore. J Biol Chem (2013) 0.99
SUV39H1 orchestrates temporal dynamics of centromeric methylation essential for faithful chromosome segregation in mitosis. J Mol Cell Biol (2012) 0.98
Probing CENP-E function in chromosome dynamics using small molecule inhibitor syntelin. Cell Res (2010) 0.98
Mitotic regulator Mis18β interacts with and specifies the centromeric assembly of molecular chaperone holliday junction recognition protein (HJURP). J Biol Chem (2014) 0.97
A multiresponsive, shape-persistent, and elastic supramolecular polymer network gel constructed by orthogonal self-assembly. Adv Mater (2011) 0.95
Investigation on the morphological protective effect of 5-hydroxymethylfurfural extracted from wine-processed Fructus corni on human L02 hepatocytes. J Ethnopharmacol (2010) 0.91
TTK kinase is essential for the centrosomal localization of TACC2. FEBS Lett (2004) 0.91
Single-molecule detection of phosphorylation-induced plasticity changes during ezrin activation. FEBS Lett (2007) 0.90
Dimerization of CPAP orchestrates centrosome cohesion plasticity. J Biol Chem (2009) 0.89
A mechanism of Munc18b-syntaxin 3-SNAP25 complex assembly in regulated epithelial secretion. FEBS Lett (2007) 0.88
Β-elemene inhibits Hsp90/Raf-1 molecular complex inducing apoptosis of glioblastoma cells. J Neurooncol (2011) 0.87
FBXL5 interacts with p150Glued and regulates its ubiquitination. Biochem Biophys Res Commun (2007) 0.86
Effect of C-reactive protein on gene expression in vascular endothelial cells. Am J Physiol Heart Circ Physiol (2004) 0.86
The synthesis of ursolic acid derivatives with cytotoxic activity and the investigation of their preliminary mechanism of action. Bioorg Med Chem (2008) 0.85
A serum-free medium for colony growth and hyaluronic acid production by Streptococcus zooepidemicus NJUST01. Appl Microbiol Biotechnol (2005) 0.85
A DNA methyltransferase inhibitor, 5-aza-2'-deoxycytidine, exacerbates neurotoxicity and upregulates Parkinson's disease-related genes in dopaminergic neurons. CNS Neurosci Ther (2013) 0.83
Metal coordination mediated reversible conversion between linear and cross-linked supramolecular polymers. Angew Chem Int Ed Engl (2010) 0.83
MTDH mediates estrogen-independent growth and tamoxifen resistance by down-regulating PTEN in MCF-7 breast cancer cells. Cell Physiol Biochem (2014) 0.82
ACAP4 protein cooperates with Grb2 protein to orchestrate epidermal growth factor-stimulated integrin β1 recycling in cell migration. J Biol Chem (2011) 0.82
Changes in small intestinal morphology and digestive enzyme activity with oral administration of copper-loaded chitosan nanoparticles in rats. Biol Trace Elem Res (2011) 0.81
Experimental cancer gene therapy by multiple anti-survivin hammerhead ribozymes. Acta Biochim Biophys Sin (Shanghai) (2008) 0.81
DNA damage-induced NF-κB activation in human glioblastoma cells promotes miR-181b expression and cell proliferation. Cell Physiol Biochem (2015) 0.81
Effects of osthole on apoptosis and TGF-beta1 of hypertrophic scar fibroblasts. J Asian Nat Prod Res (2009) 0.81
Nek2A kinase regulates the localization of numatrin to centrosome in mitosis. FEBS Lett (2004) 0.80
A dual-responsive supramolecular polymer gel formed by crown ether based molecular recognition. Angew Chem Int Ed Engl (2011) 0.80
Deep resequencing reveals allelic variation in Sesamum indicum. BMC Plant Biol (2014) 0.80
D-box is required for the degradation of human Shugoshin and chromosome alignment. Biochem Biophys Res Commun (2007) 0.80
Phosphorylation of the Bin, Amphiphysin, and RSV161/167 (BAR) domain of ACAP4 regulates membrane tubulation. Proc Natl Acad Sci U S A (2013) 0.79
Lysosomal membrane permeabilization contributes to elemene emulsion-induced apoptosis in A549 cells. Free Radic Res (2011) 0.79
Involvement of cyclin K posttranscriptional regulation in the formation of Artemia diapause cysts. PLoS One (2012) 0.79
Supramolecular polymer nanofibers via electrospinning of a heteroditopic monomer. Chem Commun (Camb) (2011) 0.78
Self-assembly of [2]pseudorotaxanes based on pillar[5]arene and bis(imidazolium) cations. Chem Commun (Camb) (2010) 0.78
Microsurgical treatment for parasagittal meningioma in the central gyrus region. Oncol Lett (2013) 0.78
In vitro angiogenesis effect of Xuefu Zhuyu Decoction () and vascular endothelial growth factor: A comparison study. Chin J Integr Med (2015) 0.77
[Effect of p38 MAPK on elemene-induced cell cycle arrest in C6 glioblastoma cells]. Zhonghua Yi Xue Za Zhi (2008) 0.77
Morpho-anatomical and physiological responses to waterlogging of sesame (Sesamum indicum L.). Plant Sci (2013) 0.76
Regulation of β cleavage of amyloid precursor protein. Neurosci Bull (2010) 0.75
Erratum: Replication fork stability confers chemoresistance in BRCA-deficient cells. Nature (2016) 0.75
[Clinical research of safflower injection on hibernating myocardial revascularization]. Zhongguo Zhong Yao Za Zhi (2014) 0.75
A novel gene mutation (1292 deletion) in a Chinese family with cerebral cavernous malformations. Neurosurgery (2005) 0.75
[Essential role of TRPC6 in the proliferation of gastric cancer and its mechanism]. Zhonghua Zhong Liu Za Zhi (2012) 0.75
New light on the ring-chain equilibrium of a hydrogen-bonded supramolecular polymer based on a photochromic dithienylethene unit and its energy-transfer properties as a storage material. Chemistry (2011) 0.75
[A study on the mechanism of drug resistance in Staphylococcus aureus]. Sichuan Da Xue Xue Bao Yi Xue Ban (2006) 0.75
[A case of occupational melanosis]. Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi (2014) 0.75
[Effect of 5-hydroxymethyl furfural on BCL-2 and NF-kappaB gene expression of apoptotic rat hippocampal neurons injured by H2O2]. Zhong Yao Cai (2011) 0.75
The DNA methyltransferase-2 gene in the prawn Macrobrachium rosenbergii: characteristics and expression patterns during ovarian and embryonic development. Zoolog Sci (2007) 0.75
A supramolecular polymer blend containing two different supramolecular polymers through self-sorting organization of two heteroditopic monomers. Chemistry (2012) 0.75
[Roles of bFGF in endothelial cell tube formation induced by xuefu zhuyu decoction under non-anoxia condition]. Zhongguo Zhong Xi Yi Jie He Za Zhi (2013) 0.75
[Studies on chemistry component and the biological activity of petroleum ether extraction from pre-and post-processed of Cornus officinalis]. Zhong Yao Cai (2010) 0.75
Cepharanthine Induces Autophagy, Apoptosis and Cell Cycle Arrest in Breast Cancer Cells. Cell Physiol Biochem (2017) 0.75
Formation of a cyclic dimer containing two mirror image monomers in the solid state controlled by van der Waals forces. Org Lett (2011) 0.75