Published in Oncogene on August 18, 2005
Emerging extranuclear roles of protein SUMOylation in neuronal function and dysfunction. Nat Rev Neurosci (2007) 1.97
Noncovalent interaction between Ubc9 and SUMO promotes SUMO chain formation. EMBO J (2007) 1.97
The SUMO-specific protease SENP5 is required for cell division. Mol Cell Biol (2006) 1.81
SUSP1 antagonizes formation of highly SUMO2/3-conjugated species. J Cell Biol (2006) 1.67
Dual modification of BMAL1 by SUMO2/3 and ubiquitin promotes circadian activation of the CLOCK/BMAL1 complex. Mol Cell Biol (2008) 1.52
The nucleolar SUMO-specific protease SENP3 reverses SUMO modification of nucleophosmin and is required for rRNA processing. EMBO Rep (2008) 1.47
Structure of the human SENP7 catalytic domain and poly-SUMO deconjugation activities for SENP6 and SENP7. J Biol Chem (2008) 1.47
A manually curated network of the PML nuclear body interactome reveals an important role for PML-NBs in SUMOylation dynamics. Int J Biol Sci (2010) 1.38
Sumo-1 function is dispensable in normal mouse development. Mol Cell Biol (2008) 1.37
Kaposi's sarcoma-associated herpesvirus (KSHV) encodes a SUMO E3 ligase that is SIM-dependent and SUMO-2/3-specific. J Biol Chem (2009) 1.23
Histone deacetylase 7 promotes PML sumoylation and is essential for PML nuclear body formation. Mol Cell Biol (2008) 1.23
Modification of nuclear PML protein by SUMO-1 regulates Fas-induced apoptosis in rheumatoid arthritis synovial fibroblasts. Proc Natl Acad Sci U S A (2007) 1.22
SENP3-mediated de-conjugation of SUMO2/3 from promyelocytic leukemia is correlated with accelerated cell proliferation under mild oxidative stress. J Biol Chem (2010) 1.16
Targeting promyelocytic leukemia protein: a means to regulating PML nuclear bodies. Int J Biol Sci (2009) 1.03
Kaposi's sarcoma-associated herpesvirus K-Rta exhibits SUMO-targeting ubiquitin ligase (STUbL) like activity and is essential for viral reactivation. PLoS Pathog (2013) 0.98
Genetic evidence that polysumoylation bypasses the need for a SUMO-targeted Ub ligase. Genetics (2010) 0.92
The SUMO protease SENP6 is a direct regulator of PML nuclear bodies. Mol Biol Cell (2010) 0.91
The PML nuclear bodies-associated protein TTRAP regulates ribosome biogenesis in nucleolar cavities upon proteasome inhibition. Cell Death Differ (2011) 0.91
Post-Translational Modifications of Kaposi's Sarcoma-Associated Herpesvirus Regulatory Proteins - SUMO and KSHV. Front Microbiol (2012) 0.89
Sp100 isoform-specific regulation of human adenovirus 5 gene expression. J Virol (2014) 0.89
Post-translational modifications of PML: consequences and implications. Front Oncol (2013) 0.88
Swapping small ubiquitin-like modifier (SUMO) isoform specificity of SUMO proteases SENP6 and SENP7. J Biol Chem (2011) 0.87
Supervillin-mediated suppression of p53 protein enhances cell survival. J Biol Chem (2013) 0.86
PML Degradation: Multiple Ways to Eliminate PML. Front Oncol (2013) 0.82
Murine gammaherpesvirus 68 ORF75c contains ubiquitin E3 ligase activity and requires PML SUMOylation but not other known cellular PML regulators, CK2 and E6AP, to mediate PML degradation. Virology (2013) 0.82
SUMO5, a Novel Poly-SUMO Isoform, Regulates PML Nuclear Bodies. Sci Rep (2016) 0.82
The function, regulation and therapeutic implications of the tumor suppressor protein, PML. Cell Biosci (2015) 0.82
PML3 Orchestrates the Nuclear Dynamics and Function of TIP60. J Biol Chem (2009) 0.81
CD2AP regulates SUMOylation of CIN85 in podocytes. Mol Cell Biol (2011) 0.81
Regulation of the tumor suppressor PML by sequential post-translational modifications. Front Oncol (2012) 0.79
Dissecting the cell to nucleus, perinucleus and cytosol. Sci Rep (2014) 0.77
SUMOhunt: Combining Spatial Staging between Lysine and SUMO with Random Forests to Predict SUMOylation. ISRN Bioinform (2013) 0.75
Analysis of Small Ubiquitin-Like Modifier (SUMO) Targets Reflects the Essential Nature of Protein SUMOylation and Provides Insight to Elucidate the Role of SUMO in Plant Development. Plant Physiol (2015) 0.75
SUMO proteomics to decipher the SUMO-modified proteome regulated by various diseases. Proteomics (2014) 0.75
A dual-kinase mechanism for Wnt co-receptor phosphorylation and activation. Nature (2005) 5.50
GPS 2.0, a tool to predict kinase-specific phosphorylation sites in hierarchy. Mol Cell Proteomics (2008) 4.33
The DNA methylome of human peripheral blood mononuclear cells. PLoS Biol (2010) 4.25
Protein production and purification. Nat Methods (2008) 3.97
FoxM1 promotes β-catenin nuclear localization and controls Wnt target-gene expression and glioma tumorigenesis. Cancer Cell (2011) 3.58
CCL18 from tumor-associated macrophages promotes breast cancer metastasis via PITPNM3. Cancer Cell (2011) 3.31
Initiation of Wnt signaling: control of Wnt coreceptor Lrp6 phosphorylation/activation via frizzled, dishevelled and axin functions. Development (2007) 3.28
CSS-Palm 2.0: an updated software for palmitoylation sites prediction. Protein Eng Des Sel (2008) 2.86
DOG 1.0: illustrator of protein domain structures. Cell Res (2009) 2.77
Microbial 2,3-butanediol production: a state-of-the-art review. Biotechnol Adv (2011) 2.59
GPS: a comprehensive www server for phosphorylation sites prediction. Nucleic Acids Res (2005) 2.44
Reciprocal inhibition between Pax7 and muscle regulatory factors modulates myogenic cell fate determination. J Cell Biol (2007) 2.44
Rho GTPase/Rho kinase negatively regulates endothelial nitric oxide synthase phosphorylation through the inhibition of protein kinase B/Akt in human endothelial cells. Mol Cell Biol (2002) 2.40
PPSP: prediction of PK-specific phosphorylation site with Bayesian decision theory. BMC Bioinformatics (2006) 2.34
Whole-genome DNA methylation profiling using MethylCap-seq. Methods (2010) 2.29
Mature adipocytes and perivascular adipose tissue stimulate vascular smooth muscle cell proliferation: effects of aging and obesity. Am J Physiol Heart Circ Physiol (2005) 2.21
GPS: a novel group-based phosphorylation predicting and scoring method. Biochem Biophys Res Commun (2004) 2.17
Decoding a new neural machine interface for control of artificial limbs. J Neurophysiol (2007) 2.11
Comprehensive analysis of microRNA expression patterns in renal biopsies of lupus nephritis patients. Rheumatol Int (2008) 2.09
Internalization of NK cells into tumor cells requires ezrin and leads to programmed cell-in-cell death. Cell Res (2009) 2.07
Meta-analysis of effectiveness of first-generation drug-eluting stents versus coronary artery bypass grafting for unprotected left main coronary disease. Am J Cardiol (2012) 2.07
Direct interaction between survivin and Smac/DIABLO is essential for the anti-apoptotic activity of survivin during taxol-induced apoptosis. J Biol Chem (2003) 2.06
Single base-resolution methylome of the silkworm reveals a sparse epigenomic map. Nat Biotechnol (2010) 2.03
Independence of repressive histone marks and chromatin compaction during senescent heterochromatic layer formation. Mol Cell (2012) 2.02
Thrombin stimulates human endothelial arginase enzymatic activity via RhoA/ROCK pathway: implications for atherosclerotic endothelial dysfunction. Circulation (2004) 1.90
SUMOsp: a web server for sumoylation site prediction. Nucleic Acids Res (2006) 1.88
Focal atrial tachycardia originating from the non-coronary aortic sinus: electrophysiological characteristics and catheter ablation. J Am Coll Cardiol (2006) 1.88
Structure of a CENP-A-histone H4 heterodimer in complex with chaperone HJURP. Genes Dev (2011) 1.87
Inhibition of GSK3 phosphorylation of beta-catenin via phosphorylated PPPSPXS motifs of Wnt coreceptor LRP6. PLoS One (2009) 1.87
Construction of a high-density genetic map for sesame based on large scale marker development by specific length amplified fragment (SLAF) sequencing. BMC Plant Biol (2013) 1.84
A novel set of DNA methylation markers in urine sediments for sensitive/specific detection of bladder cancer. Clin Cancer Res (2007) 1.77
Phosphorylation of human Sgo1 by NEK2A is essential for chromosome congression in mitosis. Cell Res (2007) 1.71
A susceptibility locus at chromosome 3p21 linked to familial nasopharyngeal carcinoma. Cancer Res (2004) 1.65
Methylation profiling of twenty promoter-CpG islands of genes which may contribute to hepatocellular carcinogenesis. BMC Cancer (2002) 1.63
Expression of seven main Rho family members in gastric carcinoma. Biochem Biophys Res Commun (2004) 1.63
Cancer-preventive activities of tocopherols and tocotrienols. Carcinogenesis (2009) 1.59
Chronic myeloid leukemia in the Asia-Pacific region: current practice, challenges and opportunities in the targeted therapy era. Leuk Res (2010) 1.59
NEK2A interacts with MAD1 and possibly functions as a novel integrator of the spindle checkpoint signaling. J Biol Chem (2004) 1.58
Electrophysiological findings during ablation of persistent atrial fibrillation with electroanatomic mapping and double Lasso catheter technique. Circulation (2005) 1.57
Migration of endothelial progenitor cells mediated by stromal cell-derived factor-1alpha/CXCR4 via PI3K/Akt/eNOS signal transduction pathway. J Cardiovasc Pharmacol (2007) 1.54
Solution structure of human Brg1 bromodomain and its specific binding to acetylated histone tails. Biochemistry (2007) 1.51
Simultaneous visualization of protumorigenic Src and MT1-MMP activities with fluorescence resonance energy transfer. Cancer Res (2010) 1.50
Prognostic significance of 2-hydroxyglutarate levels in acute myeloid leukemia in China. Proc Natl Acad Sci U S A (2013) 1.49
High-frequency deep brain stimulation of the putamen improves bradykinesia in Parkinson's disease. Mov Disord (2011) 1.45
Human Zwint-1 specifies localization of Zeste White 10 to kinetochores and is essential for mitotic checkpoint signaling. J Biol Chem (2004) 1.44
Study of stability of time-domain features for electromyographic pattern recognition. J Neuroeng Rehabil (2010) 1.43
Wnt stabilization of β-catenin reveals principles for morphogen receptor-scaffold assemblies. Science (2013) 1.43
Prolonged survival with imatinib mesylate combined with chemotherapy and allogeneic stem cell transplantation in de novo Ph+ acute myeloid leukemia. Acta Haematol (2012) 1.43
Aurora B kinase activation requires survivin priming phosphorylation by PLK1. J Mol Cell Biol (2010) 1.43
Structural basis and binding properties of the second bromodomain of Brd4 with acetylated histone tails. Biochemistry (2008) 1.43
Promyelocytic leukemia nuclear bodies behave as DNA damage sensors whose response to DNA double-strand breaks is regulated by NBS1 and the kinases ATM, Chk2, and ATR. J Cell Biol (2006) 1.43
CSS-Palm: palmitoylation site prediction with a clustering and scoring strategy (CSS). Bioinformatics (2006) 1.42
Single-base resolution maps of cultivated and wild rice methylomes and regulatory roles of DNA methylation in plant gene expression. BMC Genomics (2012) 1.40
GPS-SNO: computational prediction of protein S-nitrosylation sites with a modified GPS algorithm. PLoS One (2010) 1.40
Anti-tumor effect of beta-elemene in glioblastoma cells depends on p38 MAPK activation. Cancer Lett (2008) 1.40
Microarray analysis of MicroRNA expression in acute rejection after renal transplantation. Transpl Immunol (2008) 1.40
Mutation of the circadian clock gene Per2 alters vascular endothelial function. Circulation (2007) 1.39
Regulator of G protein signaling 5 protects against cardiac hypertrophy and fibrosis during biomechanical stress of pressure overload. Proc Natl Acad Sci U S A (2010) 1.38
Molecular dynamics simulations of peptides and proteins with amplified collective motions. Biophys J (2003) 1.38
Direct activation of human and mouse Oct4 genes using engineered TALE and Cas9 transcription factors. Nucleic Acids Res (2014) 1.34
Enhanced 2,3-butanediol production by Klebsiella oxytoca using a two-stage agitation speed control strategy. Bioresour Technol (2009) 1.33
Control of a six degree of freedom prosthetic arm after targeted muscle reinnervation surgery. Arch Phys Med Rehabil (2008) 1.33
Defective de novo methylation of viral and cellular DNA sequences in ICF syndrome cells. Hum Mol Genet (2002) 1.32
Solution structure of the second bromodomain of Brd2 and its specific interaction with acetylated histone tails. BMC Struct Biol (2007) 1.32
Phosphorylation of HsMis13 by Aurora B kinase is essential for assembly of functional kinetochore. J Biol Chem (2008) 1.30
Nudel modulates kinetochore association and function of cytoplasmic dynein in M phase. Mol Biol Cell (2007) 1.30
Simultaneous determination of six active components in crude and processed Fructus Corni by high performance liquid chromatography. J Pharm Biomed Anal (2008) 1.28
Cancer prevention by tea: Evidence from laboratory studies. Pharmacol Res (2011) 1.28
BRD7, a novel bromodomain gene, inhibits G1-S progression by transcriptionally regulating some important molecules involved in ras/MEK/ERK and Rb/E2F pathways. J Cell Physiol (2004) 1.27
Engineering Klebsiella oxytoca for efficient 2, 3-butanediol production through insertional inactivation of acetaldehyde dehydrogenase gene. Appl Microbiol Biotechnol (2009) 1.27
Human NUF2 interacts with centromere-associated protein E and is essential for a stable spindle microtubule-kinetochore attachment. J Biol Chem (2007) 1.27
Pro-oxidative activities and dose-response relationship of (-)-epigallocatechin-3-gallate in the inhibition of lung cancer cell growth: a comparative study in vivo and in vitro. Carcinogenesis (2010) 1.24
Prediction of Nepsilon-acetylation on internal lysines implemented in Bayesian Discriminant Method. Biochem Biophys Res Commun (2006) 1.24
PLK1 phosphorylates mitotic centromere-associated kinesin and promotes its depolymerase activity. J Biol Chem (2010) 1.24
Methylation profiles of thirty four promoter-CpG islands and concordant methylation behaviours of sixteen genes that may contribute to carcinogenesis of astrocytoma. BMC Cancer (2004) 1.23
Novel polymorphisms of nuclear receptor SHP associated with functional and structural changes. J Biol Chem (2010) 1.23
MicroRNA 34c gene down-regulation via DNA methylation promotes self-renewal and epithelial-mesenchymal transition in breast tumor-initiating cells. J Biol Chem (2011) 1.23
Genome-wide analysis distinguishes hyperglycemia regulated epigenetic signatures of primary vascular cells. Genome Res (2011) 1.22
Septin 7 interacts with centromere-associated protein E and is required for its kinetochore localization. J Biol Chem (2008) 1.21
Combinatorial readout of unmodified H3R2 and acetylated H3K14 by the tandem PHD finger of MOZ reveals a regulatory mechanism for HOXA9 transcription. Genes Dev (2012) 1.21
TIP150 interacts with and targets MCAK at the microtubule plus ends. EMBO Rep (2009) 1.19
Characterization of protein kinase A-mediated phosphorylation of ezrin in gastric parietal cell activation. J Biol Chem (2003) 1.19
DNA methylation-regulated miR-193a-3p dictates resistance of hepatocellular carcinoma to 5-fluorouracil via repression of SRSF2 expression. J Biol Chem (2011) 1.19
Visualization of Src activity at different compartments of the plasma membrane by FRET imaging. Chem Biol (2009) 1.18