Published in J Biol Chem on November 01, 2013
Signalling dynamics in the spindle checkpoint response. Nat Rev Mol Cell Biol (2014) 1.71
Mad1 kinetochore recruitment by Mps1-mediated phosphorylation of Bub1 signals the spindle checkpoint. Genes Dev (2014) 1.65
The Aurora B Kinase in Chromosome Bi-Orientation and Spindle Checkpoint Signaling. Front Oncol (2015) 0.91
Chromatin protein HP1 interacts with the mitotic regulator borealin protein and specifies the centromere localization of the chromosomal passenger complex. J Biol Chem (2014) 0.87
Dynamic localization of Mps1 kinase to kinetochores is essential for accurate spindle microtubule attachment. Proc Natl Acad Sci U S A (2015) 0.86
The hairpin region of Ndc80 is important for the kinetochore recruitment of Mph1/MPS1 in fission yeast. Cell Cycle (2016) 0.85
Kinetochore-microtubule attachment is sufficient to satisfy the human spindle assembly checkpoint. Nat Commun (2015) 0.84
Dynamic autophosphorylation of mps1 kinase is required for faithful mitotic progression. PLoS One (2014) 0.79
ARHGEF17 is an essential spindle assembly checkpoint factor that targets Mps1 to kinetochores. J Cell Biol (2016) 0.79
Phosphorylation at threonine 288 by cell cycle checkpoint kinase 2 (CHK2) controls human monopolar spindle 1 (Mps1) kinetochore localization. J Biol Chem (2014) 0.78
The human SKA complex drives the metaphase-anaphase cell cycle transition by recruiting protein phosphatase 1 to kinetochores. Elife (2016) 0.78
Functions of Aurora kinase C in meiosis and cancer. Front Cell Dev Biol (2015) 0.77
Dual recognition of chromatin and microtubules by INCENP is important for mitotic progression. J Cell Biol (2017) 0.75
ARHGEF17 sets the timer for retention of Mps1 at kinetochores. J Cell Biol (2016) 0.75
The spindle-assembly checkpoint in space and time. Nat Rev Mol Cell Biol (2007) 18.33
Aurora B couples chromosome alignment with anaphase by targeting BubR1, Mad2, and Cenp-E to kinetochores. J Cell Biol (2003) 9.27
The conserved KMN network constitutes the core microtubule-binding site of the kinetochore. Cell (2006) 8.44
Checkpoint inhibition of the APC/C in HeLa cells is mediated by a complex of BUBR1, BUB3, CDC20, and MAD2. J Cell Biol (2001) 6.80
Kinetochore microtubule dynamics and attachment stability are regulated by Hec1. Cell (2006) 6.46
Implications for kinetochore-microtubule attachment from the structure of an engineered Ndc80 complex. Cell (2008) 5.87
A conserved protein network controls assembly of the outer kinetochore and its ability to sustain tension. Genes Dev (2004) 5.23
Role of Hec1 in spindle checkpoint signaling and kinetochore recruitment of Mad1/Mad2. Science (2002) 4.94
The Ndc80/HEC1 complex is a contact point for kinetochore-microtubule attachment. Nat Struct Mol Biol (2006) 4.62
Activation of the budding yeast spindle assembly checkpoint without mitotic spindle disruption. Science (1996) 4.47
Sensing chromosome bi-orientation by spatial separation of aurora B kinase from kinetochore substrates. Science (2009) 4.10
Protein architecture of the human kinetochore microtubule attachment site. Cell (2009) 3.68
Dissecting the role of MPS1 in chromosome biorientation and the spindle checkpoint through the small molecule inhibitor reversine. J Cell Biol (2010) 3.50
Aurora B phosphorylates spatially distinct targets to differentially regulate the kinetochore-microtubule interface. Mol Cell (2010) 3.44
Mps1 is a kinetochore-associated kinase essential for the vertebrate mitotic checkpoint. Cell (2001) 3.16
Cdc20: a WD40 activator for a cell cycle degradation machine. Mol Cell (2007) 3.14
Microtubule attachment and spindle assembly checkpoint signalling at the kinetochore. Nat Rev Mol Cell Biol (2013) 3.01
Bub1 is required for kinetochore localization of BubR1, Cenp-E, Cenp-F and Mad2, and chromosome congression. J Cell Sci (2004) 3.01
Molecular organization of the Ndc80 complex, an essential kinetochore component. Proc Natl Acad Sci U S A (2005) 3.01
Sensing centromere tension: Aurora B and the regulation of kinetochore function. Trends Cell Biol (2010) 2.88
Kinetochore-microtubule attachment relies on the disordered N-terminal tail domain of Hec1. Curr Biol (2008) 2.79
The microtubule-dependent motor centromere-associated protein E (CENP-E) is an integral component of kinetochore corona fibers that link centromeres to spindle microtubules. J Cell Biol (1997) 2.77
Structure of the mitotic checkpoint complex. Nature (2012) 2.72
Nuf2 and Hec1 are required for retention of the checkpoint proteins Mad1 and Mad2 to kinetochores. Curr Biol (2003) 2.44
Human Mps1 kinase is required for the spindle assembly checkpoint but not for centrosome duplication. EMBO J (2002) 2.41
Human MPS1 kinase is required for mitotic arrest induced by the loss of CENP-E from kinetochores. Mol Biol Cell (2003) 2.08
Catalytic assembly of the mitotic checkpoint inhibitor BubR1-Cdc20 by a Mad2-induced functional switch in Cdc20. Mol Cell (2013) 2.06
HEC, a novel nuclear protein rich in leucine heptad repeats specifically involved in mitosis. Mol Cell Biol (1997) 1.90
Temporal changes in Hec1 phosphorylation control kinetochore-microtubule attachment stability during mitosis. J Cell Sci (2011) 1.79
Mph1, a member of the Mps1-like family of dual specificity protein kinases, is required for the spindle checkpoint in S. pombe. J Cell Sci (1998) 1.71
Evidence that Aurora B is implicated in spindle checkpoint signalling independently of error correction. EMBO J (2011) 1.62
Aurora B potentiates Mps1 activation to ensure rapid checkpoint establishment at the onset of mitosis. Nat Commun (2011) 1.59
Aurora B kinase controls the targeting of the Astrin-SKAP complex to bioriented kinetochores. J Cell Biol (2010) 1.42
A TPR domain-containing N-terminal module of MPS1 is required for its kinetochore localization by Aurora B. J Cell Biol (2013) 1.38
The MPS1 family of protein kinases. Annu Rev Biochem (2012) 1.38
The mitotic arrest in response to hypoxia and of polar bodies during early embryogenesis requires Drosophila Mps1. Curr Biol (2004) 1.34
Phosphorylation of HsMis13 by Aurora B kinase is essential for assembly of functional kinetochore. J Biol Chem (2008) 1.30
The mitotic checkpoint kinase NEK2A regulates kinetochore microtubule attachment stability. Oncogene (2008) 1.28
Human NUF2 interacts with centromere-associated protein E and is essential for a stable spindle microtubule-kinetochore attachment. J Biol Chem (2007) 1.27
Probing the in vivo function of Mad1:C-Mad2 in the spindle assembly checkpoint. EMBO J (2011) 1.19
CENP-E kinesin interacts with SKAP protein to orchestrate accurate chromosome segregation in mitosis. J Biol Chem (2011) 1.12
Spindle checkpoint silencing: PP1 tips the balance. Curr Biol (2011) 1.07
CENP-U cooperates with Hec1 to orchestrate kinetochore-microtubule attachment. J Biol Chem (2010) 1.06
Mitotic regulator SKAP forms a link between kinetochore core complex KMN and dynamic spindle microtubules. J Biol Chem (2012) 1.05
Germ cell aneuploidy in zebrafish with mutations in the mitotic checkpoint gene mps1. Genes Dev (2004) 1.03
Molecular architecture of vertebrate kinetochores. Exp Cell Res (2012) 1.02
Quantitative mass spectrometry analysis reveals similar substrate consensus motif for human Mps1 kinase and Plk1. PLoS One (2011) 1.00
Probing CENP-E function in chromosome dynamics using small molecule inhibitor syntelin. Cell Res (2010) 0.98
Dynamic distribution of TTK in HeLa cells: insights from an ultrastructural study. Cell Res (2003) 0.88
Mad2 "opens" Cdc20 for BubR1 binding. Mol Cell (2013) 0.77
Inappropriate activation of the TSC/Rheb/mTOR/S6K cassette induces IRS1/2 depletion, insulin resistance, and cell survival deficiencies. Curr Biol (2004) 7.59
Highly multiplexed molecular inversion probe genotyping: over 10,000 targeted SNPs genotyped in a single tube assay. Genome Res (2005) 6.32
GPS 2.0, a tool to predict kinase-specific phosphorylation sites in hierarchy. Mol Cell Proteomics (2008) 4.33
Downregulation of caveolin-1 function by EGF leads to the loss of E-cadherin, increased transcriptional activity of beta-catenin, and enhanced tumor cell invasion. Cancer Cell (2003) 3.87
Template-based protein structure modeling using the RaptorX web server. Nat Protoc (2012) 3.68
Identifying ChIP-seq enrichment using MACS. Nat Protoc (2012) 3.60
CCL18 from tumor-associated macrophages promotes breast cancer metastasis via PITPNM3. Cancer Cell (2011) 3.31
CSS-Palm 2.0: an updated software for palmitoylation sites prediction. Protein Eng Des Sel (2008) 2.86
DOG 1.0: illustrator of protein domain structures. Cell Res (2009) 2.77
GPS: a comprehensive www server for phosphorylation sites prediction. Nucleic Acids Res (2005) 2.44
PPSP: prediction of PK-specific phosphorylation site with Bayesian decision theory. BMC Bioinformatics (2006) 2.34
GPS: a novel group-based phosphorylation predicting and scoring method. Biochem Biophys Res Commun (2004) 2.17
Internalization of NK cells into tumor cells requires ezrin and leads to programmed cell-in-cell death. Cell Res (2009) 2.07
Direct interaction between survivin and Smac/DIABLO is essential for the anti-apoptotic activity of survivin during taxol-induced apoptosis. J Biol Chem (2003) 2.06
Crosslinkers and motors organize dynamic microtubules to form stable bipolar arrays in fission yeast. Cell (2007) 2.05
Rapamycin ameliorates proteinuria-associated tubulointerstitial inflammation and fibrosis in experimental membranous nephropathy. J Am Soc Nephrol (2005) 2.00
Highly enantioselective cyanosilylation of aldehydes catalyzed by novel beta-amino alcohol-titanium complexes. J Org Chem (2004) 1.89
SUMOsp: a web server for sumoylation site prediction. Nucleic Acids Res (2006) 1.88
Structure of a CENP-A-histone H4 heterodimer in complex with chaperone HJURP. Genes Dev (2011) 1.87
Construction of a high-density genetic map for sesame based on large scale marker development by specific length amplified fragment (SLAF) sequencing. BMC Plant Biol (2013) 1.84
A novel set of DNA methylation markers in urine sediments for sensitive/specific detection of bladder cancer. Clin Cancer Res (2007) 1.77
A different function for a member of an ancient and highly conserved cytochrome P450 family: from essential sterols to plant defense. Proc Natl Acad Sci U S A (2006) 1.71
Phosphorylation of human Sgo1 by NEK2A is essential for chromosome congression in mitosis. Cell Res (2007) 1.71
Reliability analysis of a smartphone-aided measurement method for the Cobb angle of scoliosis. J Spinal Disord Tech (2012) 1.69
Expression of seven main Rho family members in gastric carcinoma. Biochem Biophys Res Commun (2004) 1.63
NEK2A interacts with MAD1 and possibly functions as a novel integrator of the spindle checkpoint signaling. J Biol Chem (2004) 1.58
Lithium activates the Wnt and phosphatidylinositol 3-kinase Akt signaling pathways to promote cell survival in the absence of soluble survival factors. Am J Physiol Renal Physiol (2004) 1.58
Hexokinase regulates Bax-mediated mitochondrial membrane injury following ischemic stress. Kidney Int (2011) 1.58
HIF1A employs CDK8-mediator to stimulate RNAPII elongation in response to hypoxia. Cell (2013) 1.58
GPS 2.1: enhanced prediction of kinase-specific phosphorylation sites with an algorithm of motif length selection. Protein Eng Des Sel (2010) 1.53
A facile system for genetic incorporation of two different noncanonical amino acids into one protein in Escherichia coli. Angew Chem Int Ed Engl (2010) 1.52
Upregulation of neutrophil gelatinase-associated lipocalin in oesophageal squamous cell carcinoma: significant correlation with cell differentiation and tumour invasion. J Clin Pathol (2007) 1.49
Human Zwint-1 specifies localization of Zeste White 10 to kinetochores and is essential for mitotic checkpoint signaling. J Biol Chem (2004) 1.44
Hsp27 inhibits Bax activation and apoptosis via a phosphatidylinositol 3-kinase-dependent mechanism. J Biol Chem (2008) 1.44
Aurora B kinase activation requires survivin priming phosphorylation by PLK1. J Mol Cell Biol (2010) 1.43
CSS-Palm: palmitoylation site prediction with a clustering and scoring strategy (CSS). Bioinformatics (2006) 1.42
Uncoupling of the spindle-checkpoint and chromosome-congression functions of BubR1. J Cell Sci (2010) 1.42
GPS-SNO: computational prediction of protein S-nitrosylation sites with a modified GPS algorithm. PLoS One (2010) 1.40
Anti-tumor effect of beta-elemene in glioblastoma cells depends on p38 MAPK activation. Cancer Lett (2008) 1.40
Chemical anoxia of tubular cells induces activation of c-Src and its translocation to the zonula adherens. Am J Physiol Renal Physiol (2002) 1.37
Stabilization of PML nuclear localization by conjugation and oligomerization of SUMO-3. Oncogene (2005) 1.33
Gap junction remodeling and cardiac arrhythmogenesis in a murine model of oculodentodigital dysplasia. Proc Natl Acad Sci U S A (2007) 1.33
Phosphorylation of HsMis13 by Aurora B kinase is essential for assembly of functional kinetochore. J Biol Chem (2008) 1.30
Nudel modulates kinetochore association and function of cytoplasmic dynein in M phase. Mol Biol Cell (2007) 1.30
Simultaneous determination of six active components in crude and processed Fructus Corni by high performance liquid chromatography. J Pharm Biomed Anal (2008) 1.28
Genetically encoded cyclopropene directs rapid, photoclick-chemistry-mediated protein labeling in mammalian cells. Angew Chem Int Ed Engl (2012) 1.28
Human NUF2 interacts with centromere-associated protein E and is essential for a stable spindle microtubule-kinetochore attachment. J Biol Chem (2007) 1.27
Manganese ferrite nanoparticle micellar nanocomposites as MRI contrast agent for liver imaging. Biomaterials (2009) 1.25
Prediction of Nepsilon-acetylation on internal lysines implemented in Bayesian Discriminant Method. Biochem Biophys Res Commun (2006) 1.24
PLK1 phosphorylates mitotic centromere-associated kinesin and promotes its depolymerase activity. J Biol Chem (2010) 1.24
Septin 7 interacts with centromere-associated protein E and is required for its kinetochore localization. J Biol Chem (2008) 1.21
Distinct hsp70 domains mediate apoptosis-inducing factor release and nuclear accumulation. J Biol Chem (2006) 1.21
Antibiotic resistance of Helicobacter pylori isolated in the Southeast Coastal Region of China. Helicobacter (2013) 1.20
Crystal structure of human enterovirus 71 3C protease. J Mol Biol (2011) 1.20
TIP150 interacts with and targets MCAK at the microtubule plus ends. EMBO Rep (2009) 1.19
Growth of manganese oxide nanoflowers on vertically-aligned carbon nanotube arrays for high-rate electrochemical capacitive energy storage. Nano Lett (2008) 1.19
Characterization of protein kinase A-mediated phosphorylation of ezrin in gastric parietal cell activation. J Biol Chem (2003) 1.19
DNA methylation-regulated miR-193a-3p dictates resistance of hepatocellular carcinoma to 5-fluorouracil via repression of SRSF2 expression. J Biol Chem (2011) 1.19
Selective small molecules blocking HIV-1 Tat and coactivator PCAF association. J Am Chem Soc (2005) 1.18
A genetically encoded photocaged Nepsilon-methyl-L-lysine. Mol Biosyst (2010) 1.17
Three-dimensional shape measurement with an arbitrarily arranged fringe projection profilometry system. Opt Lett (2007) 1.16
PhosSNP for systematic analysis of genetic polymorphisms that influence protein phosphorylation. Mol Cell Proteomics (2009) 1.15
A genome-wide analysis of sumoylation-related biological processes and functions in human nucleus. FEBS Lett (2005) 1.15
PALS1 specifies the localization of ezrin to the apical membrane of gastric parietal cells. J Biol Chem (2005) 1.15
Sagittal alignment of spine and pelvis in asymptomatic adults: norms in Chinese populations. Spine (Phila Pa 1976) (2014) 1.14
PKA-mediated protein phosphorylation regulates ezrin-WWOX interaction. Biochem Biophys Res Commun (2006) 1.14