Published in J Am Chem Soc on May 14, 2008
Recent Advances in the Application of Solution NMR Spectroscopy to Multi-Span Integral Membrane Proteins. Prog Nucl Magn Reson Spectrosc (2009) 1.57
Immobilization of the influenza A M2 transmembrane peptide in virus envelope-mimetic lipid membranes: a solid-state NMR investigation. Biochemistry (2009) 1.54
Solid-state NMR studies of HIV-1 capsid protein assemblies. J Am Chem Soc (2010) 1.49
Membrane protein structure and dynamics from NMR spectroscopy. Annu Rev Phys Chem (2011) 1.43
Characterization of different water pools in solid-state NMR protein samples. J Biomol NMR (2009) 1.38
Assigning large proteins in the solid state: a MAS NMR resonance assignment strategy using selectively and extensively 13C-labelled proteins. J Biomol NMR (2009) 1.37
Coupling of activation and inactivation gate in a K+-channel: potassium and ligand sensitivity. EMBO J (2009) 1.26
Conformational dynamics in the selectivity filter of KcsA in response to potassium ion concentration. J Mol Biol (2010) 1.12
Reverse micelles in integral membrane protein structural biology by solution NMR spectroscopy. Structure (2009) 1.02
Lipid dynamics and protein-lipid interactions in 2D crystals formed with the β-barrel integral membrane protein VDAC1. J Am Chem Soc (2012) 0.95
Optimization of amino acid type-specific 13C and 15N labeling for the backbone assignment of membrane proteins by solution- and solid-state NMR with the UPLABEL algorithm. J Biomol NMR (2010) 0.93
Importance of lipid-pore loop interface for potassium channel structure and function. Proc Natl Acad Sci U S A (2013) 0.93
Transmembrane allosteric coupling of the gates in a potassium channel. Proc Natl Acad Sci U S A (2013) 0.91
NMR-based structural biology enhanced by dynamic nuclear polarization at high magnetic field. J Biomol NMR (2014) 0.91
Quantitative analysis of the water occupancy around the selectivity filter of a K+ channel in different gating modes. J Am Chem Soc (2014) 0.89
Secondary structure, backbone dynamics, and structural topology of phospholamban and its phosphorylated and Arg9Cys-mutated forms in phospholipid bilayers utilizing 13C and 15N solid-state NMR spectroscopy. J Phys Chem B (2014) 0.80
Extensive de novo solid-state NMR assignments of the 33 kDa C-terminal domain of the Ure2 prion. J Biomol NMR (2011) 0.80
Lipid bilayer-bound conformation of an integral membrane beta barrel protein by multidimensional MAS NMR. J Biomol NMR (2015) 0.80
Membrane proteins in their native habitat as seen by solid-state NMR spectroscopy. Protein Sci (2015) 0.80
Preparation of uniformly isotope labeled KcsA for solid state NMR: expression, purification, reconstitution into liposomes and functional assay. Protein Expr Purif (2013) 0.79
Efficient cellular solid-state NMR of membrane proteins by targeted protein labeling. J Biomol NMR (2015) 0.78
A method for solution NMR structural studies of large integral membrane proteins: reverse micelle encapsulation. Biochim Biophys Acta (2009) 0.78
Probing the interaction of Arg9Cys mutated phospholamban with phospholipid bilayers by solid-state NMR spectroscopy. Biochim Biophys Acta (2013) 0.77
Fractional deuteration applied to biomolecular solid-state NMR spectroscopy. J Biomol NMR (2011) 0.76
Probing Conformational Changes during the Gating Cycle of a Potassium Channel in Lipid Bilayers. Biophys J (2017) 0.76
Recognition dynamics up to microseconds revealed from an RDC-derived ubiquitin ensemble in solution. Science (2008) 8.04
Amyloid fibrils of the HET-s(218-289) prion form a beta solenoid with a triangular hydrophobic core. Science (2008) 5.55
Molecular-level secondary structure, polymorphism, and dynamics of full-length alpha-synuclein fibrils studied by solid-state NMR. Proc Natl Acad Sci U S A (2005) 3.37
Conditional transgenic suppression of M channels in mouse brain reveals functions in neuronal excitability, resonance and behavior. Nat Neurosci (2004) 2.70
Structure of the human voltage-dependent anion channel. Proc Natl Acad Sci U S A (2008) 2.69
Impaired endocytosis of the ion channel TRPM4 is associated with human progressive familial heart block type I. J Clin Invest (2009) 2.54
Toxin-induced conformational changes in a potassium channel revealed by solid-state NMR. Nature (2006) 2.34
Crystal structure of the endosomal SNARE complex reveals common structural principles of all SNAREs. Nat Struct Biol (2002) 2.21
Pacemaker channel dysfunction in a patient with sinus node disease. J Clin Invest (2003) 2.14
β-synuclein aggregates and induces neurodegeneration in dopaminergic neurons. Ann Neurol (2013) 2.10
Pre-fibrillar alpha-synuclein variants with impaired beta-structure increase neurotoxicity in Parkinson's disease models. EMBO J (2009) 2.09
Calmodulin is essential for cardiac IKS channel gating and assembly: impaired function in long-QT mutations. Circ Res (2006) 2.05
Atomic model of the type III secretion system needle. Nature (2012) 2.02
Determination of membrane protein structure and dynamics by magic-angle-spinning solid-state NMR spectroscopy. J Am Chem Soc (2005) 2.02
Gain-of-function mutations in TRPM4 cause autosomal dominant isolated cardiac conduction disease. Circ Cardiovasc Genet (2010) 1.92
Isoform-specific regulation of mood behavior and pancreatic beta cell and cardiovascular function by L-type Ca 2+ channels. J Clin Invest (2004) 1.69
Atomic-resolution three-dimensional structure of HET-s(218-289) amyloid fibrils by solid-state NMR spectroscopy. J Am Chem Soc (2010) 1.69
Structural constraints from proton-mediated rare-spin correlation spectroscopy in rotating solids. J Am Chem Soc (2002) 1.68
A ligand-induced switch in the periplasmic domain of sensor histidine kinase CitA. J Mol Biol (2008) 1.61
Secondary structure, dynamics, and topology of a seven-helix receptor in native membranes, studied by solid-state NMR spectroscopy. Angew Chem Int Ed Engl (2007) 1.54
A concept for rapid protein-structure determination by solid-state NMR spectroscopy. Angew Chem Int Ed Engl (2005) 1.53
3D structure determination of the Crh protein from highly ambiguous solid-state NMR restraints. J Am Chem Soc (2008) 1.46
Weak long-range correlated motions in a surface patch of ubiquitin involved in molecular recognition. J Am Chem Soc (2011) 1.45
Solid-state NMR spectroscopy on complex biomolecules. Angew Chem Int Ed Engl (2010) 1.39
N-type inactivation features of Kv4.2 channel gating. Biophys J (2004) 1.39
Crystallographic ab initio protein structure solution below atomic resolution. Nat Methods (2009) 1.38
Structural properties of pore-forming oligomers of alpha-synuclein. J Am Chem Soc (2009) 1.36
A structural link between inactivation and block of a K+ channel. Nat Struct Mol Biol (2008) 1.36
Protein refolding is required for assembly of the type three secretion needle. Nat Struct Mol Biol (2010) 1.36
A thorough dynamic interpretation of residual dipolar couplings in ubiquitin. J Biomol NMR (2006) 1.34
Self-consistent residual dipolar coupling based model-free analysis for the robust determination of nanosecond to microsecond protein dynamics. J Biomol NMR (2008) 1.33
Structure of the unphosphorylated STAT5a dimer. J Biol Chem (2005) 1.32
Structure of the mitochondrial translocator protein in complex with a diagnostic ligand. Science (2014) 1.29
Conkunitzin-S1 is the first member of a new Kunitz-type neurotoxin family. Structural and functional characterization. J Biol Chem (2005) 1.27
Systematic analysis of barrier-forming FG hydrogels from Xenopus nuclear pore complexes. EMBO J (2012) 1.27
Amyloid-like interactions within nucleoporin FG hydrogels. Proc Natl Acad Sci U S A (2010) 1.26
Coupling of activation and inactivation gate in a K+-channel: potassium and ligand sensitivity. EMBO J (2009) 1.26
Structural basis for the inhibitory role of tomosyn in exocytosis. J Biol Chem (2004) 1.26
Solid-state NMR spectroscopy on cellular preparations enhanced by dynamic nuclear polarization. Angew Chem Int Ed Engl (2012) 1.25
Cellular solid-state nuclear magnetic resonance spectroscopy. Proc Natl Acad Sci U S A (2012) 1.25
Structural rearrangements of membrane proteins probed by water-edited solid-state NMR spectroscopy. J Am Chem Soc (2009) 1.23
Analysis of proton-proton transfer dynamics in rotating solids and their use for 3D structure determination. J Am Chem Soc (2003) 1.21
Solid state NMR sequential resonance assignments and conformational analysis of the 2x10.4 kDa dimeric form of the Bacillus subtilis protein Crh. J Biomol NMR (2003) 1.21
Structural characterization of alpha-synuclein in an aggregation prone state. Protein Sci (2009) 1.18
Plasticity of the PAS domain and a potential role for signal transduction in the histidine kinase DcuS. Nat Struct Mol Biol (2008) 1.17
Structure of the NCoA-1/SRC-1 PAS-B domain bound to the LXXLL motif of the STAT6 transactivation domain. J Mol Biol (2004) 1.16
Solid-state NMR reveals structural differences between fibrils of wild-type and disease-related A53T mutant alpha-synuclein. J Mol Biol (2008) 1.16
C-terminal HERG (LQT2) mutations disrupt IKr channel regulation through 14-3-3epsilon. Hum Mol Genet (2006) 1.15
Characterization of Alzheimer's-like paired helical filaments from the core domain of tau protein using solid-state NMR spectroscopy. J Am Chem Soc (2008) 1.15
Contribution of N- and C-terminal Kv4.2 channel domains to KChIP interaction [corrected]. J Physiol (2005) 1.14
Structural analysis of the PP2C phosphatase tPphA from Thermosynechococcus elongatus: a flexible flap subdomain controls access to the catalytic site. J Mol Biol (2007) 1.14
The conformation of neurotensin bound to its G protein-coupled receptor. Proc Natl Acad Sci U S A (2003) 1.14
KCNQ1 channels sense small changes in cell volume. J Physiol (2003) 1.13
Functional dynamics in the voltage-dependent anion channel. Proc Natl Acad Sci U S A (2010) 1.13
Adsorption of polyelectrolytes and its influence on the rheology, zeta potential, and microstructure of various cement and hydrate phases. J Colloid Interface Sci (2008) 1.11
TRPM4 cation channel mediates axonal and neuronal degeneration in experimental autoimmune encephalomyelitis and multiple sclerosis. Nat Med (2012) 1.11
Structural characterization of polyglutamine fibrils by solid-state NMR spectroscopy. J Mol Biol (2011) 1.11
Bilayer in small bicelles revealed by lipid-protein interactions using NMR spectroscopy. J Am Chem Soc (2008) 1.11
High-resolution solid-state NMR studies on uniformly [13C,15N]-labeled ubiquitin. Chembiochem (2005) 1.11
High-resolution solid-state NMR applied to polypeptides and membrane proteins. Acc Chem Res (2003) 1.10
Side-chain orientation and hydrogen-bonding imprint supra-Tau(c) motion on the protein backbone of ubiquitin. Angew Chem Int Ed Engl (2005) 1.09
Modular architecture of Munc13/calmodulin complexes: dual regulation by Ca2+ and possible function in short-term synaptic plasticity. EMBO J (2009) 1.09
In support of the BMRB. Nat Struct Mol Biol (2012) 1.09
Kinetics of conformational sampling in ubiquitin. Angew Chem Int Ed Engl (2011) 1.07