Natural killer cell evasion by an E3 ubiquitin ligase from Kaposi's sarcoma-associated herpesvirus.

PubWeight™: 0.89‹?›

🔗 View Article (PMID 18481981)

Published in Biochem Soc Trans on June 01, 2008

Authors

Mair Thomas1, Mark Wills, Paul J Lehner

Author Affiliations

1: Cambridge Institute for Medical Research, University of Cambridge, Hills Road, Cambridge CB2 0XY, UK. mt351@cam.ac.uk

Articles by these authors

Lysine-63-linked ubiquitination is required for endolysosomal degradation of class I molecules. EMBO J (2006) 2.39

Ubiquitylation of MHC class I by the K3 viral protein signals internalization and TSG101-dependent degradation. EMBO J (2002) 2.23

A novel neuroprotective therapy for Parkinson's disease using a viral noncoding RNA that protects mitochondrial complex I activity. J Exp Med (2011) 2.10

Loss of function of a lupus-associated FcgammaRIIb polymorphism through exclusion from lipid rafts. Nat Med (2005) 2.01

Degradation of endocytosed epidermal growth factor and virally ubiquitinated major histocompatibility complex class I is independent of mammalian ESCRTII. J Biol Chem (2005) 1.82

Down-regulation of NKG2D and NKp80 ligands by Kaposi's sarcoma-associated herpesvirus K5 protects against NK cell cytotoxicity. Proc Natl Acad Sci U S A (2008) 1.80

Viral avoidance and exploitation of the ubiquitin system. Nat Cell Biol (2009) 1.77

Impaired natural killer cell phenotype and function in idiopathic and heritable pulmonary arterial hypertension. Circulation (2012) 1.59

Viral degradation of the MHC class I peptide loading complex. Immunity (2004) 1.51

Solution structure of the Kaposi's sarcoma-associated herpesvirus K3 N-terminal domain reveals a Novel E2-binding C4HC3-type RING domain. J Biol Chem (2004) 1.50

The TRC8 E3 ligase ubiquitinates MHC class I molecules before dislocation from the ER. J Cell Biol (2009) 1.48

The trafficking and regulation of membrane receptors by the RING-CH ubiquitin E3 ligases. Exp Cell Res (2008) 1.39

Efficient internalization of MHC I requires lysine-11 and lysine-63 mixed linkage polyubiquitin chains. Traffic (2009) 1.39

HRD1 and UBE2J1 target misfolded MHC class I heavy chains for endoplasmic reticulum-associated degradation. Proc Natl Acad Sci U S A (2011) 1.38

HIV-1 Nef-induced down-regulation of MHC class I requires AP-1 and clathrin but not PACS-1 and is impeded by AP-2. Mol Biol Cell (2007) 1.32

Latency-associated degradation of the MRP1 drug transporter during latent human cytomegalovirus infection. Science (2013) 1.27

Dendritic cell stimulation by mycobacterial Hsp70 is mediated through CCR5. Science (2006) 1.27

The dominantly expressed class I molecule of the chicken MHC is explained by coevolution with the polymorphic peptide transporter (TAP) genes. Proc Natl Acad Sci U S A (2011) 1.26

Role for the obesity-related FTO gene in the cellular sensing of amino acids. Proc Natl Acad Sci U S A (2013) 1.24

The ubiquitin E3 ligase MARCH7 is differentially regulated by the deubiquitylating enzymes USP7 and USP9X. Traffic (2008) 1.22

Immunosenescence and Cytomegalovirus: where do we stand after a decade? Immun Ageing (2010) 1.22

Report from the second cytomegalovirus and immunosenescence workshop. Immun Ageing (2011) 1.19

Stable isotope labeling by amino acids in cell culture and differential plasma membrane proteome quantitation identify new substrates for the MARCH9 transmembrane E3 ligase. Mol Cell Proteomics (2009) 1.19

Tapasin is a facilitator, not an editor, of class I MHC peptide binding. J Immunol (2003) 1.19

First report of Salmonella enterica serotype paratyphi A azithromycin resistance leading to treatment failure. J Clin Microbiol (2010) 1.17

HSP70 peptide binding mutants separate antigen delivery from dendritic cell stimulation. Immunity (2004) 1.14

Structure and function: heat shock proteins and adaptive immunity. J Immunol (2007) 1.12

Endosomal transport via ubiquitination. Trends Cell Biol (2011) 1.12

Identification of a lysosomal pathway regulating degradation of the bone morphogenetic protein receptor type II. J Biol Chem (2010) 1.05

Comparative analysis of techniques to purify plasma membrane proteins. J Biomol Tech (2010) 1.05

MARCH-IX mediates ubiquitination and downregulation of ICAM-1. FEBS Lett (2006) 1.03

Kaposi's sarcoma-associated herpesvirus K3 and K5 proteins block distinct steps in transendothelial migration of effector memory CD4+ T cells by targeting different endothelial proteins. J Immunol (2010) 1.02

RNA-binding E3 ubiquitin ligases: novel players in nucleic acid regulation. Biochem Soc Trans (2010) 1.01

The RNA-binding E3 ubiquitin ligase MEX-3C links ubiquitination with MHC-I mRNA degradation. EMBO J (2012) 0.98

Fluorescence-based phenotypic selection allows forward genetic screens in haploid human cells. PLoS One (2012) 0.98

MHC class I molecules are preferentially ubiquitinated on endoplasmic reticulum luminal residues during HRD1 ubiquitin E3 ligase-mediated dislocation. Proc Natl Acad Sci U S A (2013) 0.97

Proteomic plasma membrane profiling reveals an essential role for gp96 in the cell surface expression of LDLR family members, including the LDL receptor and LRP6. J Proteome Res (2012) 0.94

What has the study of the K3 and K5 viral ubiquitin E3 ligases taught us about ubiquitin-mediated receptor regulation? Viruses (2011) 0.90

Haploid genetic screens identify an essential role for PLP2 in the downregulation of novel plasma membrane targets by viral E3 ubiquitin ligases. PLoS Pathog (2013) 0.90

Tapasin-related protein TAPBPR is an additional component of the MHC class I presentation pathway. Proc Natl Acad Sci U S A (2013) 0.89

The varicellovirus UL49.5 protein blocks the transporter associated with antigen processing (TAP) by inhibiting essential conformational transitions in the 6+6 transmembrane TAP core complex. J Immunol (2008) 0.88

Human cytomegalovirus: taking the strain. Med Microbiol Immunol (2015) 0.84

Ubiquitination of lysine-331 by Kaposi's sarcoma-associated herpesvirus protein K5 targets HFE for lysosomal degradation. Proc Natl Acad Sci U S A (2010) 0.84

A novel post-transcriptional role for ubiquitin in the differential regulation of MHC class I allotypes. Mol Immunol (2012) 0.82

Stabilization of an E3 ligase-E2-ubiquitin complex increases cell surface MHC class I expression. J Immunol (2010) 0.82

Sterol metabolism regulates neuroserpin polymer degradation in the absence of the unfolded protein response in the dementia FENIB. Hum Mol Genet (2013) 0.82

ESCRT proteins and the regulation of endocytic delivery to lysosomes. Biochem Soc Trans (2009) 0.80

The ABC-transporter signature motif is required for peptide translocation but not peptide binding by TAP. Eur J Immunol (2003) 0.76

Jenner's irony: cowpox taps into T cell evasion. Cell Host Microbe (2009) 0.75

A 58-year-old woman with abdominal symptoms and elevated C-reactive protein. PLoS Med (2008) 0.75

Radiological Imaging: Computed Tomography, Magnetic Resonance Imaging and Ultrasonography. Front Horm Res (2015) 0.75