Published in Exp Cell Res on November 05, 2008
Molecular mechanism of BST2/tetherin downregulation by K5/MIR2 of Kaposi's sarcoma-associated herpesvirus. J Virol (2009) 2.87
MHC class I antigen presentation: learning from viral evasion strategies. Nat Rev Immunol (2009) 2.49
Construction and manipulation of a new Kaposi's sarcoma-associated herpesvirus bacterial artificial chromosome clone. J Virol (2012) 1.89
HIV-1 Vpu and HIV-2 Env counteract BST-2/tetherin by sequestration in a perinuclear compartment. Retrovirology (2010) 1.87
Viral avoidance and exploitation of the ubiquitin system. Nat Cell Biol (2009) 1.77
RING-type E3 ligases: master manipulators of E2 ubiquitin-conjugating enzymes and ubiquitination. Biochim Biophys Acta (2013) 1.64
Why do cellular proteins linked to K63-polyubiquitin chains not associate with proteasomes? EMBO J (2013) 1.53
MARCH ubiquitin ligases alter the itinerary of clathrin-independent cargo from recycling to degradation. Mol Biol Cell (2011) 1.18
Antiviral inhibition of enveloped virus release by tetherin/BST-2: action and counteraction. Viruses (2011) 1.13
Endosomal transport via ubiquitination. Trends Cell Biol (2011) 1.12
Viral hijacking of the host ubiquitin system to evade interferon responses. Curr Opin Microbiol (2010) 1.12
Intracellular assembly and trafficking of MHC class I molecules. Traffic (2009) 1.12
Adherens junction turnover: regulating adhesion through cadherin endocytosis, degradation, and recycling. Subcell Biochem (2012) 1.10
Ubiquitin-dependent sorting in endocytosis. Cold Spring Harb Perspect Biol (2014) 1.10
The UBAP1 subunit of ESCRT-I interacts with ubiquitin via a SOUBA domain. Structure (2012) 1.09
Modulation of Immune System by Kaposi's Sarcoma-Associated Herpesvirus: Lessons from Viral Evasion Strategies. Front Microbiol (2012) 0.97
MARCH2 promotes endocytosis and lysosomal sorting of carvedilol-bound β(2)-adrenergic receptors. J Cell Biol (2012) 0.96
Endocytic events in TCR signaling: focus on adapters in microclusters. Immunol Rev (2009) 0.96
Membrane-Associated RING-CH proteins associate with Bap31 and target CD81 and CD44 to lysosomes. PLoS One (2010) 0.95
Ubiquitination by the membrane-associated RING-CH-8 (MARCH-8) ligase controls steady-state cell surface expression of tumor necrosis factor-related apoptosis inducing ligand (TRAIL) receptor 1. J Biol Chem (2013) 0.94
The yeast ERAD-C ubiquitin ligase Doa10 recognizes an intramembrane degron. J Cell Biol (2015) 0.92
Major histocompatibility complex class I downregulation induced by equine herpesvirus type 1 pUL56 is through dynamin-dependent endocytosis. J Virol (2014) 0.92
Ubiquitin-mediated regulation of CD86 protein expression by the ubiquitin ligase membrane-associated RING-CH-1 (MARCH1). J Biol Chem (2011) 0.92
RNA in blood is altered prior to hemorrhagic transformation in ischemic stroke. Ann Neurol (2013) 0.91
Haploid genetic screens identify an essential role for PLP2 in the downregulation of novel plasma membrane targets by viral E3 ubiquitin ligases. PLoS Pathog (2013) 0.90
Kaposi's sarcoma-associated herpesvirus K3 and K5 ubiquitin E3 ligases have stage-specific immune evasion roles during lytic replication. J Virol (2014) 0.90
Poxvirus exploitation of the ubiquitin-proteasome system. Viruses (2010) 0.88
The Role of the Transmembrane RING Finger Proteins in Cellular and Organelle Function. Membranes (Basel) (2011) 0.87
The mitochondrial ubiquitin ligase MARCH5 resolves MAVS aggregates during antiviral signalling. Nat Commun (2015) 0.86
MHC class II antigen presentation by dendritic cells regulated through endosomal sorting. Cold Spring Harb Perspect Biol (2013) 0.83
Membrane-associated RING-CH 10 (MARCH10 protein) is a microtubule-associated E3 ubiquitin ligase of the spermatid flagella. J Biol Chem (2011) 0.83
Ubiquitination and degradation of CFTR by the E3 ubiquitin ligase MARCH2 through its association with adaptor proteins CAL and STX6. PLoS One (2013) 0.82
Stabilization of an E3 ligase-E2-ubiquitin complex increases cell surface MHC class I expression. J Immunol (2010) 0.82
The MARCH family E3 ubiquitin ligase K5 alters monocyte metabolism and proliferation through receptor tyrosine kinase modulation. PLoS Pathog (2011) 0.82
Intracellular Transport Routes for MHC I and Their Relevance for Antigen Cross-Presentation. Front Immunol (2015) 0.82
Identification of SAMT family proteins as substrates of MARCH11 in mouse spermatids. Histochem Cell Biol (2011) 0.80
Evasion of adaptive and innate immune response mechanisms by γ-herpesviruses. Curr Opin Virol (2013) 0.79
The Membrane Associated RING-CH Proteins: A Family of E3 Ligases with Diverse Roles through the Cell. Int Sch Res Notices (2014) 0.78
Protein homeostasis at the plasma membrane. Physiology (Bethesda) (2014) 0.78
The Missing Link in Epstein-Barr Virus Immune Evasion: the BDLF3 Gene Induces Ubiquitination and Downregulation of Major Histocompatibility Complex Class I (MHC-I) and MHC-II. J Virol (2015) 0.78
A small molecule compound IMB-LA inhibits HIV-1 infection by preventing viral Vpu from antagonizing the host restriction factor BST-2. Sci Rep (2015) 0.77
Quantitating MHC class II trafficking in primary dendritic cells using imaging flow cytometry. J Immunol Methods (2015) 0.77
T Cell Priming by Activated Nlrc5-Deficient Dendritic Cells Is Unaffected despite Partially Reduced MHC Class I Levels. J Immunol (2016) 0.77
Silencing MARCH1 suppresses proliferation, migration and invasion of ovarian cancer SKOV3 cells via downregulation of NF-κB and Wnt/β-catenin pathways. Oncol Rep (2016) 0.76
Split-Doa10: a naturally split polytopic eukaryotic membrane protein generated by fission of a nuclear gene. PLoS One (2012) 0.76
Ubiquitination regulates the morphogenesis and function of sperm organelles. Cells (2013) 0.76
Inhibition of MARCH5 ubiquitin ligase abrogates MCL1-dependent resistance to BH3 mimetics via NOXA. Oncotarget (2016) 0.75
MARCH5 RNA promotes autophagy, migration, and invasion of ovarian cancer cells. Autophagy (2016) 0.75
MARCH1 regulates insulin sensitivity by controlling cell surface insulin receptor levels. Nat Commun (2016) 0.75
Lysine-63-linked ubiquitination is required for endolysosomal degradation of class I molecules. EMBO J (2006) 2.39
Ubiquitylation of MHC class I by the K3 viral protein signals internalization and TSG101-dependent degradation. EMBO J (2002) 2.23
Loss of function of a lupus-associated FcgammaRIIb polymorphism through exclusion from lipid rafts. Nat Med (2005) 2.01
Degradation of endocytosed epidermal growth factor and virally ubiquitinated major histocompatibility complex class I is independent of mammalian ESCRTII. J Biol Chem (2005) 1.82
Down-regulation of NKG2D and NKp80 ligands by Kaposi's sarcoma-associated herpesvirus K5 protects against NK cell cytotoxicity. Proc Natl Acad Sci U S A (2008) 1.80
Viral avoidance and exploitation of the ubiquitin system. Nat Cell Biol (2009) 1.77
Viral degradation of the MHC class I peptide loading complex. Immunity (2004) 1.51
Solution structure of the Kaposi's sarcoma-associated herpesvirus K3 N-terminal domain reveals a Novel E2-binding C4HC3-type RING domain. J Biol Chem (2004) 1.50
The TRC8 E3 ligase ubiquitinates MHC class I molecules before dislocation from the ER. J Cell Biol (2009) 1.48
Efficient internalization of MHC I requires lysine-11 and lysine-63 mixed linkage polyubiquitin chains. Traffic (2009) 1.39
HRD1 and UBE2J1 target misfolded MHC class I heavy chains for endoplasmic reticulum-associated degradation. Proc Natl Acad Sci U S A (2011) 1.38
HIV-1 Nef-induced down-regulation of MHC class I requires AP-1 and clathrin but not PACS-1 and is impeded by AP-2. Mol Biol Cell (2007) 1.32
Latency-associated degradation of the MRP1 drug transporter during latent human cytomegalovirus infection. Science (2013) 1.27
Dendritic cell stimulation by mycobacterial Hsp70 is mediated through CCR5. Science (2006) 1.27
The dominantly expressed class I molecule of the chicken MHC is explained by coevolution with the polymorphic peptide transporter (TAP) genes. Proc Natl Acad Sci U S A (2011) 1.26
Role for the obesity-related FTO gene in the cellular sensing of amino acids. Proc Natl Acad Sci U S A (2013) 1.24
The ubiquitin E3 ligase MARCH7 is differentially regulated by the deubiquitylating enzymes USP7 and USP9X. Traffic (2008) 1.22
Stable isotope labeling by amino acids in cell culture and differential plasma membrane proteome quantitation identify new substrates for the MARCH9 transmembrane E3 ligase. Mol Cell Proteomics (2009) 1.19
Tapasin is a facilitator, not an editor, of class I MHC peptide binding. J Immunol (2003) 1.19
First report of Salmonella enterica serotype paratyphi A azithromycin resistance leading to treatment failure. J Clin Microbiol (2010) 1.17
HSP70 peptide binding mutants separate antigen delivery from dendritic cell stimulation. Immunity (2004) 1.14
Structure and function: heat shock proteins and adaptive immunity. J Immunol (2007) 1.12
Endosomal transport via ubiquitination. Trends Cell Biol (2011) 1.12
Identification of a lysosomal pathway regulating degradation of the bone morphogenetic protein receptor type II. J Biol Chem (2010) 1.05
Comparative analysis of techniques to purify plasma membrane proteins. J Biomol Tech (2010) 1.05
MARCH-IX mediates ubiquitination and downregulation of ICAM-1. FEBS Lett (2006) 1.03
Kaposi's sarcoma-associated herpesvirus K3 and K5 proteins block distinct steps in transendothelial migration of effector memory CD4+ T cells by targeting different endothelial proteins. J Immunol (2010) 1.02
RNA-binding E3 ubiquitin ligases: novel players in nucleic acid regulation. Biochem Soc Trans (2010) 1.01
The RNA-binding E3 ubiquitin ligase MEX-3C links ubiquitination with MHC-I mRNA degradation. EMBO J (2012) 0.98
Fluorescence-based phenotypic selection allows forward genetic screens in haploid human cells. PLoS One (2012) 0.98
MHC class I molecules are preferentially ubiquitinated on endoplasmic reticulum luminal residues during HRD1 ubiquitin E3 ligase-mediated dislocation. Proc Natl Acad Sci U S A (2013) 0.97
Proteomic plasma membrane profiling reveals an essential role for gp96 in the cell surface expression of LDLR family members, including the LDL receptor and LRP6. J Proteome Res (2012) 0.94
What has the study of the K3 and K5 viral ubiquitin E3 ligases taught us about ubiquitin-mediated receptor regulation? Viruses (2011) 0.90
Haploid genetic screens identify an essential role for PLP2 in the downregulation of novel plasma membrane targets by viral E3 ubiquitin ligases. PLoS Pathog (2013) 0.90
Natural killer cell evasion by an E3 ubiquitin ligase from Kaposi's sarcoma-associated herpesvirus. Biochem Soc Trans (2008) 0.89
Tapasin-related protein TAPBPR is an additional component of the MHC class I presentation pathway. Proc Natl Acad Sci U S A (2013) 0.89
The varicellovirus UL49.5 protein blocks the transporter associated with antigen processing (TAP) by inhibiting essential conformational transitions in the 6+6 transmembrane TAP core complex. J Immunol (2008) 0.88
Human cytomegalovirus: taking the strain. Med Microbiol Immunol (2015) 0.84
Ubiquitination of lysine-331 by Kaposi's sarcoma-associated herpesvirus protein K5 targets HFE for lysosomal degradation. Proc Natl Acad Sci U S A (2010) 0.84
A novel post-transcriptional role for ubiquitin in the differential regulation of MHC class I allotypes. Mol Immunol (2012) 0.82
Sterol metabolism regulates neuroserpin polymer degradation in the absence of the unfolded protein response in the dementia FENIB. Hum Mol Genet (2013) 0.82
Stabilization of an E3 ligase-E2-ubiquitin complex increases cell surface MHC class I expression. J Immunol (2010) 0.82
ESCRT proteins and the regulation of endocytic delivery to lysosomes. Biochem Soc Trans (2009) 0.80
The ABC-transporter signature motif is required for peptide translocation but not peptide binding by TAP. Eur J Immunol (2003) 0.76
Jenner's irony: cowpox taps into T cell evasion. Cell Host Microbe (2009) 0.75
A 58-year-old woman with abdominal symptoms and elevated C-reactive protein. PLoS Med (2008) 0.75