Published in Mol Biol Cell on June 20, 2007
Rapid inactivation of proteins by rapamycin-induced rerouting to mitochondria. Dev Cell (2010) 1.82
The subcellular distribution of calnexin is mediated by PACS-2. Mol Biol Cell (2008) 1.51
HIV-1 Nef targets MHC-I and CD4 for degradation via a final common beta-COP-dependent pathway in T cells. PLoS Pathog (2008) 1.50
The Epstein-Barr virus G-protein-coupled receptor contributes to immune evasion by targeting MHC class I molecules for degradation. PLoS Pathog (2009) 1.31
Cargo recognition in clathrin-mediated endocytosis. Cold Spring Harb Perspect Biol (2013) 1.27
A diacidic motif in human immunodeficiency virus type 1 Nef is a novel determinant of binding to AP-2. J Virol (2007) 1.25
Redundant roles of BIG2 and BIG1, guanine-nucleotide exchange factors for ADP-ribosylation factors in membrane traffic between the trans-Golgi network and endosomes. Mol Biol Cell (2008) 1.24
HIV-1 Nef binds PACS-2 to assemble a multikinase cascade that triggers major histocompatibility complex class I (MHC-I) down-regulation: analysis using short interfering RNA and knock-out mice. J Biol Chem (2008) 1.22
A cytoplasmic tail determinant in HIV-1 Vpu mediates targeting of tetherin for endosomal degradation and counteracts interferon-induced restriction. PLoS Pathog (2012) 1.21
A basic patch on alpha-adaptin is required for binding of human immunodeficiency virus type 1 Nef and cooperative assembly of a CD4-Nef-AP-2 complex. J Virol (2009) 1.17
At the crossroads of homoeostasis and disease: roles of the PACS proteins in membrane traffic and apoptosis. Biochem J (2009) 1.15
Cooperative binding of the class I major histocompatibility complex cytoplasmic domain and human immunodeficiency virus type 1 Nef to the endosomal AP-1 complex via its mu subunit. J Virol (2007) 1.12
Auxilin depletion causes self-assembly of clathrin into membraneless cages in vivo. Traffic (2008) 1.06
Mechanisms of HIV-1 Nef function and intracellular signaling. J Neuroimmune Pharmacol (2011) 1.04
Human immunodeficiency virus type 1 Nef protein targets CD4 to the multivesicular body pathway. J Virol (2009) 1.00
Trafficking of vesicular neurotransmitter transporters. Traffic (2008) 0.99
Immune responses to Epstein-Barr virus: molecular interactions in the virus evasion of CD8+ T cell immunity. Microbes Infect (2010) 0.94
HIV-1 Nef binds a subpopulation of MHC-I throughout its trafficking itinerary and down-regulates MHC-I by perturbing both anterograde and retrograde trafficking. J Biol Chem (2010) 0.91
The activity of Nef on HIV-1 infectivity. Front Microbiol (2014) 0.90
Functional characterization of the human immunodeficiency virus type 1 Nef acidic domain. J Virol (2008) 0.89
HIV immune evasion disruption of antigen presentation by the HIV Nef protein. Adv Virus Res (2011) 0.89
Exosomes: Implications in HIV-1 Pathogenesis. Viruses (2015) 0.87
Inhibition of HIV-1 infection and replication by enhancing viral incorporation of innate anti-HIV-1 protein A3G: a non-pathogenic Nef mutant-based anti-HIV strategy. J Biol Chem (2009) 0.85
Sorting of Clathrin-Independent Cargo Proteins Depends on Rab35 Delivered by Clathrin-Mediated Endocytosis. Traffic (2015) 0.84
MicroRNAs in HIV-1 infection: an integration of viral and cellular interaction at the genomic level. Front Microbiol (2012) 0.84
p53 increases MHC class I expression by upregulating the endoplasmic reticulum aminopeptidase ERAP1. Nat Commun (2013) 0.84
The AP-1 complex regulates intracellular localization of insulin receptor substrate 1, which is required for insulin-like growth factor I-dependent cell proliferation. Mol Cell Biol (2013) 0.82
Intracellular Transport Routes for MHC I and Their Relevance for Antigen Cross-Presentation. Front Immunol (2015) 0.82
Nef neutralizes the ability of exosomes from CD4+ T cells to act as decoys during HIV-1 infection. PLoS One (2014) 0.81
The natural killer cell cytotoxic function is modulated by HIV-1 accessory proteins. Viruses (2011) 0.81
Interaction of HIV-1 Nef protein with the host protein Alix promotes lysosomal targeting of CD4 receptor. J Biol Chem (2014) 0.80
Human immunodeficiency virus type 1 nef expression prevents AP-2-mediated internalization of the major histocompatibility complex class II-associated invariant chain. J Virol (2008) 0.78
A Genome-Wide Screen for Machinery Involved in Downregulation of MHC Class I by HIV-1 Nef. PLoS One (2015) 0.77
Nef promotes evasion of human immunodeficiency virus type 1-infected cells from the CTLA-4-mediated inhibition of T-cell activation. J Gen Virol (2015) 0.77
Intracellular overexpression of HIV-1 Nef impairs differentiation and maturation of monocytic precursors towards dendritic cells. PLoS One (2012) 0.76
A noncanonical mu-1A-binding motif in the N terminus of HIV-1 Nef determines its ability to downregulate major histocompatibility complex class I in T lymphocytes. J Virol (2012) 0.76
Adaptor protein complexes AP-1 and AP-3 are required by the HHV-7 Immunoevasin U21 for rerouting of class I MHC molecules to the lysosomal compartment. PLoS One (2014) 0.76
HIV-1 Nef inhibits Protease activity and its absence alters protein content of mature viral particles. PLoS One (2014) 0.76
TE-domestication and horizontal transfer in a putative Nef-AP1mu mimic of HLA-A cytoplasmic domain re-trafficking. Mob Genet Elements (2016) 0.75
Isolation of a monoclonal antibody from a phage display library binding the rhesus macaque MHC class I allomorph Mamu-A1*001. PLoS One (2017) 0.75
Contribution of the clathrin adaptor AP-1 subunit µ1 to acidic cluster protein sorting. J Cell Biol (2017) 0.75
Expression profiling reveals off-target gene regulation by RNAi. Nat Biotechnol (2003) 16.63
Production of monoclonal antibodies to group A erythrocytes, HLA and other human cell surface antigens-new tools for genetic analysis. Cell (1978) 14.82
Endocytosis of major histocompatibility complex class I molecules is induced by the HIV-1 Nef protein. Nat Med (1996) 7.08
HIV-1 Nef protein protects infected primary cells against killing by cytotoxic T lymphocytes. Nature (1998) 6.94
Clathrin-mediated endocytosis in AP-2-depleted cells. J Cell Biol (2003) 6.35
The biogenesis of multivesicular endosomes. Nat Rev Mol Cell Biol (2004) 6.31
Adaptable adaptors for coated vesicles. Trends Cell Biol (2004) 5.01
Cargo-selective endosomal sorting for retrieval to the Golgi requires retromer. J Cell Biol (2004) 4.60
Viral strategies of immune evasion. Science (1998) 4.48
Analysis of clathrin-mediated endocytosis of epidermal growth factor receptor by RNA interference. J Biol Chem (2004) 4.32
Ligands for clathrin-mediated endocytosis are differentially sorted into distinct populations of early endosomes. Cell (2006) 3.83
PACS-1 defines a novel gene family of cytosolic sorting proteins required for trans-Golgi network localization. Cell (1998) 3.79
Adaptor-related proteins. Curr Opin Cell Biol (2001) 3.60
Association of the AP-3 adaptor complex with clathrin. Science (1998) 3.42
A tubular EHD1-containing compartment involved in the recycling of major histocompatibility complex class I molecules to the plasma membrane. EMBO J (2002) 3.35
AP-2/Eps15 interaction is required for receptor-mediated endocytosis. J Cell Biol (1998) 3.30
The SH3 domain-binding surface and an acidic motif in HIV-1 Nef regulate trafficking of class I MHC complexes. EMBO J (1998) 3.17
Partial purification and some properties of BB7.2. A cytotoxic monoclonal antibody with specificity for HLA-A2 and a variant of HLA-A28. Hum Immunol (1981) 3.01
A family of proteins with gamma-adaptin and VHS domains that facilitate trafficking between the trans-Golgi network and the vacuole/lysosome. J Cell Biol (2000) 2.98
Nef interacts with the mu subunit of clathrin adaptor complexes and reveals a cryptic sorting signal in MHC I molecules. Immunity (1998) 2.95
HIV-1 Nef protein binds to the cellular protein PACS-1 to downregulate class I major histocompatibility complexes. Nat Cell Biol (2000) 2.95
Localization of the AP-3 adaptor complex defines a novel endosomal exit site for lysosomal membrane proteins. J Cell Biol (2004) 2.76
An acidic sequence within the cytoplasmic domain of furin functions as a determinant of trans-Golgi network localization and internalization from the cell surface. EMBO J (1995) 2.54
A dileucine motif in HIV-1 Nef is essential for sorting into clathrin-coated pits and for downregulation of CD4. Curr Biol (1998) 2.50
Functional equivalents of interferon-mediated signals needed for induction of an mRNA can be generated by double-stranded RNA and growth factors. EMBO J (1987) 2.40
HIV-1 Nef downregulates MHC-I by a PACS-1- and PI3K-regulated ARF6 endocytic pathway. Cell (2002) 2.27
PACS-1 binding to adaptors is required for acidic cluster motif-mediated protein traffic. EMBO J (2001) 2.26
Human immunodeficiency virus type 1 Nef: adapting to intracellular trafficking pathways. Microbiol Mol Biol Rev (2006) 2.25
Recognition of dileucine-based sorting signals from HIV-1 Nef and LIMP-II by the AP-1 gamma-sigma1 and AP-3 delta-sigma3 hemicomplexes. J Cell Biol (2003) 2.24
Ubiquitylation of MHC class I by the K3 viral protein signals internalization and TSG101-dependent degradation. EMBO J (2002) 2.23
HLA-A- and HLA-B-specific monoclonal antibodies reactive with free heavy chains in western blots, in formalin-fixed, paraffin-embedded tissue sections and in cryo-immuno-electron microscopy. Int Immunol (1990) 2.12
EpsinR: an ENTH domain-containing protein that interacts with AP-1. Mol Biol Cell (2003) 2.04
The plasma membrane as a combat zone in the HIV battlefield. Genes Dev (2000) 2.02
Role of the endocytic machinery in the sorting of lysosome-associated membrane proteins. Mol Biol Cell (2005) 1.99
Downregulation of CD4 by human immunodeficiency virus type 1 Nef is dependent on clathrin and involves direct interaction of Nef with the AP2 clathrin adaptor. J Virol (2007) 1.90
HIV-1 Nef disrupts MHC-I trafficking by recruiting AP-1 to the MHC-I cytoplasmic tail. J Cell Biol (2004) 1.84
Comparative proteomics of clathrin-coated vesicles. J Cell Biol (2006) 1.83
Antigen presentation and the ubiquitin-proteasome system in host-pathogen interactions. Adv Immunol (2006) 1.78
The downregulation of CD4 and MHC-I by primate lentiviruses: a paradigm for the modulation of cell surface receptors. Immunol Rev (1999) 1.77
Functional analysis of AP-2 alpha and mu2 subunits. Mol Biol Cell (2006) 1.67
Involvement of clathrin and AP-2 in the trafficking of MHC class II molecules to antigen-processing compartments. Proc Natl Acad Sci U S A (2005) 1.47
HIV's evasion of the cellular immune response. Immunol Rev (1999) 1.46
EpsinR is an adaptor for the SNARE protein Vti1b. Mol Biol Cell (2004) 1.45
Distinct trafficking pathways mediate Nef-induced and clathrin-dependent major histocompatibility complex class I down-regulation. J Virol (2000) 1.44
Comparison of one-dimensional IEF patterns for serologically detectable HLA-A and B allotypes. Immunogenetics (1984) 1.43
Nef-mediated disruption of HLA-A2 transport to the cell surface in T cells. J Virol (2003) 1.32
Role of PACS-1 in trafficking of human cytomegalovirus glycoprotein B and virus production. J Virol (2003) 1.31
AP2 clathrin adaptor complex, but not AP1, controls the access of the major histocompatibility complex (MHC) class II to endosomes. J Biol Chem (2005) 1.30
The phosphorylation state of an autoregulatory domain controls PACS-1-directed protein traffic. EMBO J (2003) 1.22
The Eps15 C. elegans homologue EHS-1 is implicated in synaptic vesicle recycling. Nat Cell Biol (2001) 1.18
Human immunodeficiency virus-1 Nef expression induces intracellular accumulation of multivesicular bodies and major histocompatibility complex class II complexes: potential role of phosphatidylinositol 3-kinase. Mol Biol Cell (2003) 1.18
HSP70 peptide binding mutants separate antigen delivery from dendritic cell stimulation. Immunity (2004) 1.14
Sequences within the cytoplasmic domain of gp180/carboxypeptidase D mediate localization to the trans-Golgi network. Mol Biol Cell (1999) 1.14
HIV-1 Nef disrupts antigen presentation early in the secretory pathway. J Biol Chem (2005) 1.12
Characterization of MHC Class II Compartments by Immunoelectron Microscopy Methods (1996) 1.08
Membrane traffic: GGAs sort ubiquitin. Curr Biol (2004) 1.05
HLA-A2 antigen phosphorylation in vitro by cyclic AMP-dependent protein kinase. Sites of phosphorylation and segmentation in class i major histocompatibility complex gene structure. J Biol Chem (1984) 0.93
Sorting of major cargo glycoproteins into clathrin-coated vesicles. Traffic (2005) 0.93
Traffic control of completely assembled MHC class I molecules beyond the endoplasmic reticulum. J Mol Biol (1997) 0.88
Nucleotide sequence of the HLA-A26 class I gene: identification of specific residues and molecular mapping of public HLA class I epitopes. Hum Immunol (1990) 0.77
Clathrin-mediated endocytosis in AP-2-depleted cells. J Cell Biol (2003) 6.35
Rab27a and Rab27b control different steps of the exosome secretion pathway. Nat Cell Biol (2009) 5.44
Protein interaction mapping: a Drosophila case study. Genome Res (2005) 4.15
Human macrophages accumulate HIV-1 particles in MHC II compartments. Traffic (2002) 3.39
The fifth adaptor protein complex. PLoS Biol (2011) 2.94
Functions of adaptor protein (AP)-3 and AP-1 in tyrosinase sorting from endosomes to melanosomes. Mol Biol Cell (2005) 2.56
Lysine-63-linked ubiquitination is required for endolysosomal degradation of class I molecules. EMBO J (2006) 2.39
Ubiquitylation of MHC class I by the K3 viral protein signals internalization and TSG101-dependent degradation. EMBO J (2002) 2.23
EpsinR: an ENTH domain-containing protein that interacts with AP-1. Mol Biol Cell (2003) 2.04
Loss of function of a lupus-associated FcgammaRIIb polymorphism through exclusion from lipid rafts. Nat Med (2005) 2.01
Analysis of ESCRT functions in exosome biogenesis, composition and secretion highlights the heterogeneity of extracellular vesicles. J Cell Sci (2013) 1.98
Assembly and function of AP-3 complexes in cells expressing mutant subunits. J Cell Biol (2002) 1.96
Comparative proteomics of clathrin-coated vesicles. J Cell Biol (2006) 1.83
Degradation of endocytosed epidermal growth factor and virally ubiquitinated major histocompatibility complex class I is independent of mammalian ESCRTII. J Biol Chem (2005) 1.82
Rapid inactivation of proteins by rapamycin-induced rerouting to mitochondria. Dev Cell (2010) 1.82
Down-regulation of NKG2D and NKp80 ligands by Kaposi's sarcoma-associated herpesvirus K5 protects against NK cell cytotoxicity. Proc Natl Acad Sci U S A (2008) 1.80
Viral avoidance and exploitation of the ubiquitin system. Nat Cell Biol (2009) 1.77
Functional analysis of AP-2 alpha and mu2 subunits. Mol Biol Cell (2006) 1.67
The molecular basis for the endocytosis of small R-SNAREs by the clathrin adaptor CALM. Cell (2011) 1.66
A SNARE-adaptor interaction is a new mode of cargo recognition in clathrin-coated vesicles. Nature (2007) 1.61
Multivariate proteomic profiling identifies novel accessory proteins of coated vesicles. J Cell Biol (2012) 1.59
Viral degradation of the MHC class I peptide loading complex. Immunity (2004) 1.51
Solution structure of the Kaposi's sarcoma-associated herpesvirus K3 N-terminal domain reveals a Novel E2-binding C4HC3-type RING domain. J Biol Chem (2004) 1.50
The TRC8 E3 ligase ubiquitinates MHC class I molecules before dislocation from the ER. J Cell Biol (2009) 1.48
HIV-1 buds and accumulates in "nonacidic" endosomes of macrophages. Cell Host Microbe (2007) 1.47
Multiple roles of the invariant chain in MHC class II function. Biochim Biophys Acta (2002) 1.46
EpsinR is an adaptor for the SNARE protein Vti1b. Mol Biol Cell (2004) 1.45
Exosomes bearing HLA-DR1 molecules need dendritic cells to efficiently stimulate specific T cells. Int Immunol (2002) 1.41
The trafficking and regulation of membrane receptors by the RING-CH ubiquitin E3 ligases. Exp Cell Res (2008) 1.39
Efficient internalization of MHC I requires lysine-11 and lysine-63 mixed linkage polyubiquitin chains. Traffic (2009) 1.39
HRD1 and UBE2J1 target misfolded MHC class I heavy chains for endoplasmic reticulum-associated degradation. Proc Natl Acad Sci U S A (2011) 1.38
Spatial and functional relationship of GGAs and AP-1 in Drosophila and HeLa cells. Traffic (2009) 1.33
A targeted siRNA screen to identify SNAREs required for constitutive secretion in mammalian cells. Traffic (2010) 1.32
Structural basis for binding of accessory proteins by the appendage domain of GGAs. Nat Struct Biol (2003) 1.32
AP2 clathrin adaptor complex, but not AP1, controls the access of the major histocompatibility complex (MHC) class II to endosomes. J Biol Chem (2005) 1.30
Analysis of articulation between clathrin and retromer in retrograde sorting on early endosomes. Traffic (2009) 1.30
Latency-associated degradation of the MRP1 drug transporter during latent human cytomegalovirus infection. Science (2013) 1.27
Distinct and overlapping roles for AP-1 and GGAs revealed by the "knocksideways" system. Curr Biol (2012) 1.27
Dendritic cell stimulation by mycobacterial Hsp70 is mediated through CCR5. Science (2006) 1.27
The dominantly expressed class I molecule of the chicken MHC is explained by coevolution with the polymorphic peptide transporter (TAP) genes. Proc Natl Acad Sci U S A (2011) 1.26
Role for the obesity-related FTO gene in the cellular sensing of amino acids. Proc Natl Acad Sci U S A (2013) 1.24
The ubiquitin E3 ligase MARCH7 is differentially regulated by the deubiquitylating enzymes USP7 and USP9X. Traffic (2008) 1.22
Cleavage of Toll-like receptor 3 by cathepsins B and H is essential for signaling. Proc Natl Acad Sci U S A (2012) 1.21
Binding partners for the COOH-terminal appendage domains of the GGAs and gamma-adaptin. Mol Biol Cell (2003) 1.21
The aftiphilin/p200/gamma-synergin complex. Mol Biol Cell (2005) 1.19
Stable isotope labeling by amino acids in cell culture and differential plasma membrane proteome quantitation identify new substrates for the MARCH9 transmembrane E3 ligase. Mol Cell Proteomics (2009) 1.19
Tapasin is a facilitator, not an editor, of class I MHC peptide binding. J Immunol (2003) 1.19
Human immunodeficiency virus-1 Nef expression induces intracellular accumulation of multivesicular bodies and major histocompatibility complex class II complexes: potential role of phosphatidylinositol 3-kinase. Mol Biol Cell (2003) 1.18
A basic patch on alpha-adaptin is required for binding of human immunodeficiency virus type 1 Nef and cooperative assembly of a CD4-Nef-AP-2 complex. J Virol (2009) 1.17
Sdmg1 is a conserved transmembrane protein associated with germ cell sex determination and germline-soma interactions in mice. Development (2008) 1.17
First report of Salmonella enterica serotype paratyphi A azithromycin resistance leading to treatment failure. J Clin Microbiol (2010) 1.17
A screen for endocytic motifs. Traffic (2010) 1.15
HSP70 peptide binding mutants separate antigen delivery from dendritic cell stimulation. Immunity (2004) 1.14
Structure and function: heat shock proteins and adaptive immunity. J Immunol (2007) 1.12
Interaction between AP-5 and the hereditary spastic paraplegia proteins SPG11 and SPG15. Mol Biol Cell (2013) 1.12
Endosomal transport via ubiquitination. Trends Cell Biol (2011) 1.12
A dual function for Pex3p in peroxisome formation and inheritance. J Cell Biol (2009) 1.11
How peroxisomes multiply. J Cell Sci (2009) 1.09
A human genome-wide screen for regulators of clathrin-coated vesicle formation reveals an unexpected role for the V-ATPase. Nat Cell Biol (2013) 1.09
A multi-Fc-species system for recombinant antibody production. BMC Biotechnol (2009) 1.08
Asparagine endopeptidase can initiate the removal of the MHC class II invariant chain chaperone. Immunity (2003) 1.07
Auxilin depletion causes self-assembly of clathrin into membraneless cages in vivo. Traffic (2008) 1.06
Identification of a lysosomal pathway regulating degradation of the bone morphogenetic protein receptor type II. J Biol Chem (2010) 1.05
Comparative analysis of techniques to purify plasma membrane proteins. J Biomol Tech (2010) 1.05
The role of cargo proteins in GGA recruitment. Traffic (2007) 1.04
MARCH-IX mediates ubiquitination and downregulation of ICAM-1. FEBS Lett (2006) 1.03
Kaposi's sarcoma-associated herpesvirus K3 and K5 proteins block distinct steps in transendothelial migration of effector memory CD4+ T cells by targeting different endothelial proteins. J Immunol (2010) 1.02
RNA-binding E3 ubiquitin ligases: novel players in nucleic acid regulation. Biochem Soc Trans (2010) 1.01
CVAK104 is a novel regulator of clathrin-mediated SNARE sorting. Traffic (2007) 1.00
The RNA-binding E3 ubiquitin ligase MEX-3C links ubiquitination with MHC-I mRNA degradation. EMBO J (2012) 0.98
Coiled-coil interactions are required for post-Golgi R-SNARE trafficking. EMBO Rep (2009) 0.98
Fluorescence-based phenotypic selection allows forward genetic screens in haploid human cells. PLoS One (2012) 0.98
Critical role for the kinesin KIF3A in the HIV life cycle in primary human macrophages. J Cell Biol (2012) 0.97
MHC class I molecules are preferentially ubiquitinated on endoplasmic reticulum luminal residues during HRD1 ubiquitin E3 ligase-mediated dislocation. Proc Natl Acad Sci U S A (2013) 0.97
Impaired neuronal migration and endochondral ossification in Pex7 knockout mice: a model for rhizomelic chondrodysplasia punctata. Hum Mol Genet (2003) 0.96
Proteomic plasma membrane profiling reveals an essential role for gp96 in the cell surface expression of LDLR family members, including the LDL receptor and LRP6. J Proteome Res (2012) 0.94
Dynamics of HIV-containing compartments in macrophages reveal sequestration of virions and transient surface connections. PLoS One (2013) 0.94
Genetic and phenotypic analysis of the mouse mutant mh2J, an Ap3d allele caused by IAP element insertion. Mamm Genome (2003) 0.93
Sorting of major cargo glycoproteins into clathrin-coated vesicles. Traffic (2005) 0.93
AP-1 and ARF1 control endosomal dynamics at sites of FcR mediated phagocytosis. Mol Biol Cell (2007) 0.91
What has the study of the K3 and K5 viral ubiquitin E3 ligases taught us about ubiquitin-mediated receptor regulation? Viruses (2011) 0.90
Haploid genetic screens identify an essential role for PLP2 in the downregulation of novel plasma membrane targets by viral E3 ubiquitin ligases. PLoS Pathog (2013) 0.90
CD36-specific antibodies block release of HIV-1 from infected primary macrophages and its transmission to T cells. J Exp Med (2013) 0.90
HIV trafficking in host cells: motors wanted! Trends Cell Biol (2013) 0.89
Natural killer cell evasion by an E3 ubiquitin ligase from Kaposi's sarcoma-associated herpesvirus. Biochem Soc Trans (2008) 0.89
Developmental regulation of MHC II expression and transport in human plasmacytoid-derived dendritic cells. Blood (2008) 0.89
Tapasin-related protein TAPBPR is an additional component of the MHC class I presentation pathway. Proc Natl Acad Sci U S A (2013) 0.89
The varicellovirus UL49.5 protein blocks the transporter associated with antigen processing (TAP) by inhibiting essential conformational transitions in the 6+6 transmembrane TAP core complex. J Immunol (2008) 0.88
Prevention of mantle lymphoma tumor establishment by routing transferrin receptor toward lysosomal compartments. Cancer Res (2007) 0.88
Single Nef proteins from HIV type 1 subtypes C and F fail to upregulate invariant chain cell surface expression but are active for other functions. AIDS Res Hum Retroviruses (2009) 0.87
Uncoupling the functions of CALM in VAMP sorting and clathrin-coated pit formation. PLoS One (2013) 0.87