Published in J Biomed Inform on April 07, 2008
Multi-scale characterization of the PEPCK-C mouse through 3D cryo-imaging. Int J Biomed Imaging (2010) 0.84
Registration of whole immunohistochemical slide images: an efficient way to characterize biomarker colocalization. J Am Med Inform Assoc (2014) 0.83
Active contours without edges. IEEE Trans Image Process (2001) 29.63
Multimodality image registration by maximization of mutual information. IEEE Trans Med Imaging (1997) 16.80
Effects of an Rb mutation in the mouse. Nature (1992) 11.06
Mice deficient for Rb are nonviable and show defects in neurogenesis and haematopoiesis. Nature (1992) 8.16
The new stereological tools: disector, fractionator, nucleator and point sampled intercepts and their use in pathological research and diagnosis. APMIS (1988) 6.75
Stereological methods for estimating the total number of neurons and synapses: issues of precision and bias. Trends Neurosci (1999) 5.15
Non-rigid image registration: theory and practice. Br J Radiol (2004) 4.46
Extra-embryonic function of Rb is essential for embryonic development and viability. Nature (2003) 3.92
Automated segmentation, classification, and tracking of cancer cell nuclei in time-lapse microscopy. IEEE Trans Biomed Eng (2006) 3.45
Consistent landmark and intensity-based image registration. IEEE Trans Med Imaging (2002) 3.45
Three-dimensional average-shape atlas of the honeybee brain and its applications. J Comp Neurol (2005) 2.17
Rb is critical in a mammalian tissue stem cell population. Genes Dev (2007) 1.92
Rb function in extraembryonic lineages suppresses apoptosis in the CNS of Rb-deficient mice. Proc Natl Acad Sci U S A (2003) 1.74
Comparative evaluation of multiresolution optimization strategies for multimodality image registration by maximization of mutual information. Med Image Anal (1999) 1.69
Automated 3-D registration of MR and CT images of the head. Med Image Anal (1996) 1.67
Virtual mouse placenta: tissue layer segmentation. Conf Proc IEEE Eng Med Biol Soc (2005) 1.63
A prototype for unsupervised analysis of tissue microarrays for cancer research and diagnostics. IEEE Trans Inf Technol Biomed (2004) 1.55
Stereological length estimation using spherical probes. J Microsc (2002) 1.53
Three-dimensional reconstruction and quantification of cervical carcinoma invasion fronts from histological serial sections. IEEE Trans Med Imaging (2005) 1.47
High-resolution large-scale mosaic imaging using multiphoton microscopy to characterize transgenic mouse models of human neurological disorders. Neuroinformatics (2006) 1.16
3D modelling, gene expression mapping and post-mapping image analysis in the developing human brain. Brain Res Bull (2005) 1.10
Multiscale hybrid linear models for lossy image representation. IEEE Trans Image Process (2006) 0.78
Detection and visualization of surface-pockets to enable phenotyping studies. IEEE Trans Med Imaging (2007) 0.78
caGrid: design and implementation of the core architecture of the cancer biomedical informatics grid. Bioinformatics (2006) 9.83
caGrid 1.0: an enterprise Grid infrastructure for biomedical research. J Am Med Inform Assoc (2007) 6.15
Emerging roles of E2Fs in cancer: an exit from cell cycle control. Nat Rev Cancer (2009) 4.66
An integrative approach for in silico glioma research. IEEE Trans Biomed Eng (2010) 4.55
Neural palmitoyl-proteomics reveals dynamic synaptic palmitoylation. Nature (2008) 4.52
Pten in stromal fibroblasts suppresses mammary epithelial tumours. Nature (2009) 4.21
AZD2171: a highly potent, orally bioavailable, vascular endothelial growth factor receptor-2 tyrosine kinase inhibitor for the treatment of cancer. Cancer Res (2005) 4.21
Extra-embryonic function of Rb is essential for embryonic development and viability. Nature (2003) 3.92
Direct evidence for epithelial-mesenchymal transitions in breast cancer. Cancer Res (2008) 3.41
Endoscopic ultrasound as a first test for diagnosis and staging of lung cancer: a prospective study. Am J Respir Crit Care Med (2006) 3.35
Mll partial tandem duplication induces aberrant Hox expression in vivo via specific epigenetic alterations. J Clin Invest (2006) 3.27
Integrated morphologic analysis for the identification and characterization of disease subtypes. J Am Med Inform Assoc (2012) 2.68
Synergistic function of E2F7 and E2F8 is essential for cell survival and embryonic development. Dev Cell (2008) 2.61
A data model and database for high-resolution pathology analytical image informatics. J Pathol Inform (2011) 2.54
Retinoblastoma promotes definitive erythropoiesis by repressing Id2 in fetal liver macrophages. Nature (2004) 2.49
Neuroligins mediate excitatory and inhibitory synapse formation: involvement of PSD-95 and neurexin-1beta in neuroligin-induced synaptic specificity. J Biol Chem (2005) 2.29
E2f1-3 switch from activators in progenitor cells to repressors in differentiating cells. Nature (2009) 2.22
GridIMAGE: a novel use of grid computing to support interactive human and computer-assisted detection decision support. J Digit Imaging (2007) 2.21
Palmitoylation of huntingtin by HIP14 is essential for its trafficking and function. Nat Neurosci (2006) 2.19
Genomic alterations in tumor stroma. Cancer Res (2009) 2.18
Ets1 and Ets2 are required for endothelial cell survival during embryonic angiogenesis. Blood (2009) 2.17
The Cancer Biomedical Informatics Grid (caBIG) Security Infrastructure. AMIA Annu Symp Proc (2007) 2.11
The virtual microscope. IEEE Trans Inf Technol Biomed (2003) 2.06
Identification and characterization of E2F7, a novel mammalian E2F family member capable of blocking cellular proliferation. J Biol Chem (2003) 2.04
Comparative study on ChIP-seq data: normalization and binding pattern characterization. Bioinformatics (2009) 2.02
caGrid 1.0: a Grid enterprise architecture for cancer research. AMIA Annu Symp Proc (2007) 1.96
Cloning and characterization of mouse E2F8, a novel mammalian E2F family member capable of blocking cellular proliferation. J Biol Chem (2005) 1.95
Rb regulates proliferation and rod photoreceptor development in the mouse retina. Nat Genet (2004) 1.94
Rb is critical in a mammalian tissue stem cell population. Genes Dev (2007) 1.92
Dramatic increase of Cesarean deliveries in the midst of health reforms in rural China. Soc Sci Med (2010) 1.91
The proneural molecular signature is enriched in oligodendrogliomas and predicts improved survival among diffuse gliomas. PLoS One (2010) 1.86
Informatics in radiology: GridCAD: grid-based computer-aided detection system. Radiographics (2007) 1.84
JNK3 perpetuates metabolic stress induced by Aβ peptides. Neuron (2012) 1.80
MR imaging predictors of molecular profile and survival: multi-institutional study of the TCGA glioblastoma data set. Radiology (2013) 1.77
Accelerating Large Scale Image Analyses on Parallel, CPU-GPU Equipped Systems. IPDPS (2012) 1.76
Preferential electrical coupling regulates neocortical lineage-dependent microcircuit assembly. Nature (2012) 1.75
Rb function in extraembryonic lineages suppresses apoptosis in the CNS of Rb-deficient mice. Proc Natl Acad Sci U S A (2003) 1.74
MicroRNA-199b targets the nuclear kinase Dyrk1a in an auto-amplification loop promoting calcineurin/NFAT signalling. Nat Cell Biol (2010) 1.74
Evidence for a stepwise program of extrathymic T cell development within the human tonsil. J Clin Invest (2012) 1.72
Cognitive impairment in people diagnosed with end-stage liver disease evaluated for liver transplantation. Psychiatry Clin Neurosci (2006) 1.70
E2F-8: an E2F family member with a similar organization of DNA-binding domains to E2F-7. Oncogene (2005) 1.69
The WWOX tumor suppressor is essential for postnatal survival and normal bone metabolism. J Biol Chem (2008) 1.67
Integrative, multimodal analysis of glioblastoma using TCGA molecular data, pathology images, and clinical outcomes. IEEE Trans Biomed Eng (2011) 1.63
Virtual mouse placenta: tissue layer segmentation. Conf Proc IEEE Eng Med Biol Soc (2005) 1.63
Efficient Irregular Wavefront Propagation Algorithms on Hybrid CPU-GPU Machines. Parallel Comput (2013) 1.62
Salicylate-based anti-inflammatory drugs inhibit the early lesion of diabetic retinopathy. Diabetes (2007) 1.61
Aberrant regulation of survivin by the RB/E2F family of proteins. J Biol Chem (2004) 1.58
Atypical E2Fs: new players in the E2F transcription factor family. Trends Cell Biol (2009) 1.56
The dose-response decrease in heart rate variability: any association with the metabolites of polycyclic aromatic hydrocarbons in coke oven workers? PLoS One (2012) 1.55
E2f1, E2f2, and E2f3 control E2F target expression and cellular proliferation via a p53-dependent negative feedback loop. Mol Cell Biol (2007) 1.55
Division and apoptosis of E2f-deficient retinal progenitors. Nature (2009) 1.55
Hadoop-GIS: A High Performance Spatial Data Warehousing System over MapReduce. Proceedings VLDB Endowment (2013) 1.55
Decrease in the oral bioavailability of dabigatran etexilate after co-medication with rifampicin. Br J Clin Pharmacol (2012) 1.53
Pemphigus vulgaris identifies plakoglobin as key suppressor of c-Myc in the skin. EMBO J (2006) 1.52
Reconstruction of cellular biological structures from optical microscopy data. IEEE Trans Vis Comput Graph (2008) 1.52
Analysis of Cdc6 function in the assembly of mammalian prereplication complexes. Proc Natl Acad Sci U S A (2002) 1.51
Specificity of E2F1, E2F2, and E2F3 in mediating phenotypes induced by loss of Rb. Cell Growth Differ (2002) 1.51
Mouse development with a single E2F activator. Nature (2008) 1.51
ErbB4-neuregulin signaling modulates synapse development and dendritic arborization through distinct mechanisms. J Biol Chem (2008) 1.46
Does prenatal maternal stress impair cognitive development and alter temperament characteristics in toddlers with healthy birth outcomes? Dev Med Child Neurol (2014) 1.45
Image analysis for neuroblastoma classification: segmentation of cell nuclei. Conf Proc IEEE Eng Med Biol Soc (2006) 1.45
Improving normal tissue complication probability models: the need to adopt a "data-pooling" culture. Int J Radiat Oncol Biol Phys (2010) 1.44