Published in Am J Pathol on May 23, 2008
The biology of Hodgkin's lymphoma. Nat Rev Cancer (2008) 3.31
Tumor-infiltrating macrophages correlate with adverse prognosis and Epstein-Barr virus status in classical Hodgkin's lymphoma. Haematologica (2010) 1.54
The inflammatory chemokine CCL5 and cancer progression. Mediators Inflamm (2014) 1.33
Lack of association of tumor-associated macrophages with clinical outcome in patients with classical Hodgkin's lymphoma. Ann Oncol (2011) 1.15
CCR6 marks regulatory T cells as a colon-tropic, IL-10-producing phenotype. J Immunol (2010) 1.11
Tumor-infiltrating PD1-Positive Lymphocytes and FoxP3-Positive Regulatory T Cells Predict Distant Metastatic Relapse and Survival of Clear Cell Renal Cell Carcinoma. Transl Oncol (2013) 1.08
Interleukin 15 provides relief to CTLs from regulatory T cell-mediated inhibition: implications for adoptive T cell-based therapies for lymphoma. Clin Cancer Res (2012) 1.06
Epstein-Barr virus latent genes. Exp Mol Med (2015) 0.96
CD4(+)CD25(+) T regulatory cells inhibit CD8(+) IFN-gamma production during acute and chronic FIV infection utilizing a membrane TGF-beta-dependent mechanism. AIDS Res Hum Retroviruses (2010) 0.96
Distribution, characterization, and induction of CD8+ regulatory T cells and IL-17-producing CD8+ T cells in nasopharyngeal carcinoma. J Transl Med (2011) 0.96
The four types of Tregs in malignant lymphomas. J Hematol Oncol (2011) 0.93
EBV and HIV-Related Lymphoma. Mediterr J Hematol Infect Dis (2009) 0.91
Regulatory T-cell trafficking: from thymic development to tumor-induced immune suppression. Crit Rev Immunol (2010) 0.90
Inflammation and tissue repair markers distinguish the nodular sclerosis and mixed cellularity subtypes of classical Hodgkin's lymphoma. Br J Cancer (2009) 0.89
T-Cell Traffic Jam in Hodgkin's Lymphoma: Pathogenetic and Therapeutic Implications. Adv Hematol (2010) 0.88
Changes in chemokines and chemokine receptor expression on tonsillar B cells upon Epstein-Barr virus infection. Immunology (2009) 0.87
Epstein-Barr virus-encoded EBNA1 inhibits the canonical NF-kappaB pathway in carcinoma cells by inhibiting IKK phosphorylation. Mol Cancer (2010) 0.87
Peripheral natural killer cell and allo-stimulated T-cell function in kidney transplant recipients associate with cancer risk and immunosuppression-related complications. Kidney Int (2015) 0.85
Immune escape of γ-herpesviruses from adaptive immunity. Rev Med Virol (2014) 0.84
EBV infection is common in gingival epithelial cells of the periodontium and worsens during chronic periodontitis. PLoS One (2013) 0.83
How I treat classical Hodgkin lymphoma in patients infected with human immunodeficiency virus. Blood (2014) 0.83
Epstein-Barr virus and the origin of Hodgkin lymphoma. Chin J Cancer (2014) 0.82
Epstein-Barr virus encoded dUTPase containing exosomes modulate innate and adaptive immune responses in human dendritic cells and peripheral blood mononuclear cells. PLoS One (2013) 0.81
Immunological deregulation in classic hodgkin lymphoma. Mediterr J Hematol Infect Dis (2014) 0.81
The role of cytotoxic and regulatory T cells in relapsed/refractory Hodgkin lymphoma. Appl Immunohistochem Mol Morphol (2010) 0.81
Genotype-dependent tumor regression in Marek's disease mediated at the level of tumor immunity. Cancer Microenviron (2009) 0.80
Role of immune escape mechanisms in Hodgkin's lymphoma development and progression: a whole new world with therapeutic implications. Clin Dev Immunol (2012) 0.80
A rho GDP dissociation inhibitor produced by apoptotic T-cells inhibits growth of Mycobacterium tuberculosis. PLoS Pathog (2015) 0.80
Immune regulation and evasion of Mammalian host cell immunity during viral infection. Indian J Virol (2013) 0.79
Nuclear Factor kappa B is central to Marek's disease herpesvirus induced neoplastic transformation of CD30 expressing lymphocytes in-vivo. BMC Syst Biol (2012) 0.78
EBV in Hodgkin Lymphoma. Mediterr J Hematol Infect Dis (2009) 0.78
Cancer prevention in HIV-infected populations. Semin Oncol (2015) 0.77
Immune profiling and cancer post transplantation. World J Nephrol (2015) 0.77
Accumulation Mechanisms of CD4(+)CD25(+)FOXP3(+) Regulatory T Cells in EBV-associated Gastric Carcinoma. Sci Rep (2015) 0.76
Epstein-Barr virus infection and nasopharyngeal carcinoma. Philos Trans R Soc Lond B Biol Sci (2017) 0.75
Gene Expression Profiling for In Silico Microdissection of Hodgkin's Lymphoma Microenvironment and Identification of Prognostic Features. Adv Hematol (2010) 0.75
The role of T cells in the microenvironment of Hodgkin lymphoma. J Leukoc Biol (2015) 0.75
Mutations in BALB mitochondrial DNA induce CCL20 up-regulation promoting tumorigenic phenotypes. Mutat Res (2014) 0.75
Prior mucosal exposure to heterologous cells alters the pathogenesis of cell-associated mucosal feline immunodeficiency virus challenge. Retrovirology (2010) 0.75
Classical Hodgkin Lymphoma with Positive Epstein-Barr Virus Status is Associated with More FOXP3 Regulatory T Cells. Med Sci Monit (2016) 0.75
Herpesviruses dUTPases: A New Family of Pathogen-Associated Molecular Pattern (PAMP) Proteins with Implications for Human Disease. Pathogens (2016) 0.75
Summaries of Affymetrix GeneChip probe level data. Nucleic Acids Res (2003) 52.74
Rank products: a simple, yet powerful, new method to detect differentially regulated genes in replicated microarray experiments. FEBS Lett (2004) 11.00
Epstein-Barr virus: 40 years on. Nat Rev Cancer (2004) 9.70
Treatment of nasopharyngeal carcinoma with Epstein-Barr virus--specific T lymphocytes. Blood (2004) 4.01
CCR6 expression defines regulatory effector/memory-like cells within the CD25(+)CD4+ T-cell subset. Blood (2004) 2.80
Epstein-Barr virus and oncogenesis: from latent genes to tumours. Oncogene (2003) 2.72
Outcome in Hodgkin's lymphoma can be predicted from the presence of accompanying cytotoxic and regulatory T cells. Clin Cancer Res (2005) 2.60
Immunosuppressive regulatory T cells are abundant in the reactive lymphocytes of Hodgkin lymphoma. Blood (2003) 2.47
The role of the transcription factor Foxp3 in the development of regulatory T cells. Immunol Rev (2006) 2.36
The majority of human peripheral blood CD4+CD25highFoxp3+ regulatory T cells bear functional skin-homing receptors. J Immunol (2006) 2.06
Detection and localization of Mip-3alpha/LARC/Exodus, a macrophage proinflammatory chemokine, and its CCR6 receptor in human pancreatic cancer. Int J Cancer (1999) 1.81
Down-regulation of the TGF-beta target gene, PTPRK, by the Epstein-Barr virus encoded EBNA1 contributes to the growth and survival of Hodgkin lymphoma cells. Blood (2007) 1.32
T-regulatory 1 cells: a novel subset of CD4 T cells with immunoregulatory properties. J Allergy Clin Immunol (2000) 1.29
Enhanced expression and clinical significance of CC-chemokine MIP-3 alpha in hepatocellular carcinoma. Scand J Immunol (2006) 1.17
Modulation of host gene expression by the K15 protein of Kaposi's sarcoma-associated herpesvirus. J Virol (2006) 1.13
Common and differential chemokine expression patterns in rs cells of NLP, EBV positive and negative classical Hodgkin lymphomas. Int J Cancer (2002) 1.09
Rapid in situ hybridization for the diagnosis of latent Epstein-Barr virus infection. Mol Cell Probes (1993) 1.09
Human B cells immortalized with Epstein-Barr virus upregulate CCR6 and CCR10 and downregulate CXCR4 and CXCR5. J Virol (2002) 1.08
The role of virus-induced regulatory T cells in immunopathology. Springer Semin Immunopathol (2006) 1.05
Induction of autotaxin by the Epstein-Barr virus promotes the growth and survival of Hodgkin lymphoma cells. Blood (2005) 1.04
Interleukin 6 expression by Hodgkin/Reed-Sternberg cells is associated with the presence of 'B' symptoms and failure to achieve complete remission in patients with advanced Hodgkin's disease. Br J Haematol (2002) 1.04
Epstein-Barr virus-specific cytotoxic T lymphocyte responses in the blood and tumor site of Hodgkin's disease patients: implications for a T-cell-based therapy. Cancer Res (2001) 1.02
Local suppression of Epstein-Barr virus (EBV)-specific cytotoxicity in biopsies of EBV-positive Hodgkin's disease. Blood (1995) 1.01
Chemokine CCL20 enhances the growth of HuH7 cells via phosphorylation of p44/42 MAPK in vitro. Biochem Biophys Res Commun (2004) 0.99
Co-localization of macrophage inflammatory protein-3alpha (Mip-3alpha) and its receptor, CCR6, promotes pancreatic cancer cell invasion. Cancer J (2005) 0.98
Cellular retinoic acid-binding protein 2 is down-regulated in prostate cancer. Int J Oncol (2005) 0.95
Infiltration of Th1 and Th2 lymphocytes around Hodgkin and Reed-Sternberg (H&RS) cells in Hodgkin disease: Relation with expression of CXC and CC chemokines on H&RS cells. Int J Cancer (2002) 0.92
Macrophage-derived chemokine expression in classical Hodgkin's lymphoma: application of tissue microarrays. Mod Pathol (2001) 0.90
Increased serum levels of macrophage inflammatory protein-3alpha in hepatocellular carcinoma: relationship with clinical factors and prognostic importance during therapy. Int J Mol Med (2003) 0.90
The role of chemokines in Hodgkin's disease. Leuk Lymphoma (2000) 0.90
Epstein-Barr virus DNA in Reed-Sternberg cells of Hodgkin's disease is frequently associated with CR2 (EBV receptor) expression. Histopathology (1992) 0.88
CD4(+) T-cell responses to Epstein-Barr virus (EBV) latent membrane protein 1 in infectious mononucleosis and EBV-associated non-Hodgkin lymphoma: Th1 in active disease but Tr1 in remission. Br J Haematol (2007) 0.88
Hodgkin's disease expressing follicular dendritic cell marker CD21 without any other B-cell marker: a clinicopathologic study of nine cases. Am J Surg Pathol (1999) 0.86
Immunoregulatory T cells in the peripheral blood of patients with Hodgkin's lymphoma. Acta Haematol (2006) 0.85
Retracted Transactivation of CCL20 gene by Epstein-Barr virus latent membrane protein 1. Br J Haematol (2006) 0.83
Nasopharyngeal carcinoma and the EBV-specific T cell response: prospects for immunotherapy. Semin Cancer Biol (2002) 0.80
Becker muscular dystrophy in a patient with Hodgkin's disease. J Pediatr Hematol Oncol (2004) 0.78
Adoptive immunotherapy for Hodgkin's lymphoma. Int J Hematol (2006) 0.78
Expression of heat shock protein 70 (HSP70) and EBV latent membrane protein 1 (LMP1) in Reed-Sternberg cells of Hodgkin's disease. Anal Cell Pathol (1996) 0.78
Whole-genome sequencing to delineate Mycobacterium tuberculosis outbreaks: a retrospective observational study. Lancet Infect Dis (2012) 7.18
Integrated molecular genetic profiling of pediatric high-grade gliomas reveals key differences with the adult disease. J Clin Oncol (2010) 4.94
HIF activation identifies early lesions in VHL kidneys: evidence for site-specific tumor suppressor function in the nephron. Cancer Cell (2002) 4.82
The natural history of cervical HPV infection: unresolved issues. Nat Rev Cancer (2007) 3.99
Cross-species genomics matches driver mutations and cell compartments to model ependymoma. Nature (2010) 3.70
Deregulated expression of cytokine receptor gene, CRLF2, is involved in lymphoid transformation in B-cell precursor acute lymphoblastic leukemia. Blood (2009) 3.50
Novel markers for differentiation of lobular and ductal invasive breast carcinomas by laser microdissection and microarray analysis. BMC Cancer (2007) 3.16
Epstein-Barr virus and oncogenesis: from latent genes to tumours. Oncogene (2003) 2.72
Should grade 3 endometrioid endometrial carcinoma be considered a type 2 cancer-a clinical and pathological evaluation. Gynecol Oncol (2011) 2.57
Evaluation of the 8q24 prostate cancer risk locus and MYC expression. Cancer Res (2009) 2.54
Risk of acute myeloid leukemia and myelodysplastic syndromes after multiple myeloma and its precursor disease (MGUS). Blood (2011) 2.54
Hepatitis C virus infects the endothelial cells of the blood-brain barrier. Gastroenterology (2011) 2.51
Mutation of ALMS1, a large gene with a tandem repeat encoding 47 amino acids, causes Alström syndrome. Nat Genet (2002) 2.50
Gene expression perturbation in vitro--a growing case for three-dimensional (3D) culture systems. Semin Cancer Biol (2005) 2.35
Markers of survival and metastatic potential in childhood CNS primitive neuro-ectodermal brain tumours: an integrative genomic analysis. Lancet Oncol (2012) 2.34
Particle size and surface charge affect particle uptake by human dendritic cells in an in vitro model. Int J Pharm (2005) 2.21
Choroidal vessel diameter in central serous chorioretinopathy. Acta Ophthalmol (2013) 2.16
Epstein-Barr virus latent membrane protein 1 (LMP1) activates the phosphatidylinositol 3-kinase/Akt pathway to promote cell survival and induce actin filament remodeling. J Biol Chem (2002) 2.08
Epstein-Barr virus-encoded latent infection membrane protein 1 regulates the processing of p100 NF-kappaB2 to p52 via an IKKgamma/NEMO-independent signalling pathway. Oncogene (2003) 1.98
WW domains provide a platform for the assembly of multiprotein networks. Mol Cell Biol (2005) 1.97
CXCR3-dependent recruitment and CCR6-mediated positioning of Th-17 cells in the inflamed liver. J Hepatol (2012) 1.95
Non-invasive detection of a small number of bioluminescent cancer cells in vivo. PLoS One (2010) 1.92
Assessment of tumor characteristic gene expression in cell lines using a tissue similarity index (TSI). Proc Natl Acad Sci U S A (2005) 1.78
Systems medicine and integrated care to combat chronic noncommunicable diseases. Genome Med (2011) 1.78
Cancer attractors: a systems view of tumors from a gene network dynamics and developmental perspective. Semin Cell Dev Biol (2009) 1.78
Combined burn and smoke inhalation injury impairs ovine hypoxic pulmonary vasoconstriction. Crit Care Med (2006) 1.77
Early diagnosis of in utero and intrapartum HIV infection in infants prior to 6 weeks of age. J Clin Microbiol (2012) 1.76
Target cells of Epstein-Barr-virus (EBV)-positive post-transplant lymphoproliferative disease: similarities to EBV-positive Hodgkin's lymphoma. Lancet (2003) 1.70
The EBV oncogene LMP1 protects lymphoma cells from cell death through the collagen-mediated activation of DDR1. Blood (2013) 1.62
CD81 and claudin 1 coreceptor association: role in hepatitis C virus entry. J Virol (2008) 1.62
Distinct roles for CCR4 and CXCR3 in the recruitment and positioning of regulatory T cells in the inflamed human liver. J Immunol (2010) 1.61
Nodule formation and desmoplasia in medulloblastomas-defining the nodular/desmoplastic variant and its biological behavior. Brain Pathol (2007) 1.59
The role of the EBV-encoded latent membrane proteins LMP1 and LMP2 in the pathogenesis of nasopharyngeal carcinoma (NPC). Semin Cancer Biol (2012) 1.56
Virus-directed enzyme prodrug therapy: intratumoral administration of a replication-deficient adenovirus encoding nitroreductase to patients with resectable liver cancer. J Clin Oncol (2004) 1.54
High frequency somatic mutations in RASSF1A in nasopharyngeal carcinoma. Cancer Biol Ther (2005) 1.53
Increased vascular access complications in patients with renal dysfunction undergoing percutaneous coronary procedures using arteriotomy closure devices. J Invasive Cardiol (2010) 1.52
Prognostic impact of tumour-infiltrating Th2 and regulatory T cells in classical Hodgkin lymphoma. Hematol Oncol (2009) 1.50
Comparison of plasma Epstein-Barr virus (EBV) DNA levels and serum EBV immunoglobulin A/virus capsid antigen antibody titers in patients with nasopharyngeal carcinoma. Cancer (2004) 1.49
Survival and prognostic factors of early childhood medulloblastoma: an international meta-analysis. J Clin Oncol (2010) 1.48
A phase II study of adoptive immunotherapy using dendritic cells pulsed with tumor lysate in patients with hepatocellular carcinoma. Hepatology (2009) 1.46
Sudden gains as a long-term predictor of treatment improvement among children in community mental health organizations. Behav Res Ther (2013) 1.43
Prognostic impact of gene expression-based classification for neuroblastoma. J Clin Oncol (2010) 1.43
Human papillomavirus type 18 and rapidly progressing cervical intraepithelial neoplasia. Lancet (2003) 1.42
RBSP3 (HYA22) is a tumor suppressor gene implicated in major epithelial malignancies. Proc Natl Acad Sci U S A (2004) 1.39
Histopathological grading of pediatric ependymoma: reproducibility and clinical relevance in European trial cohorts. J Negat Results Biomed (2011) 1.39
Intravenous mesenchymal stem cell therapy early after reperfused acute myocardial infarction improves left ventricular function and alters electrophysiologic properties. Int J Cardiol (2005) 1.37
Combined genome-wide allelotyping and copy number analysis identify frequent genetic losses without copy number reduction in medulloblastoma. Genes Chromosomes Cancer (2006) 1.35
Isolation of primary human hepatocytes from normal and diseased liver tissue: a one hundred liver experience. PLoS One (2011) 1.34
Chronic graft-versus-host disease is associated with increased numbers of peripheral blood CD4+CD25high regulatory T cells. Blood (2003) 1.33
High incidence of cervical human papillomavirus infection in women during their first sexual relationship. BJOG (2002) 1.33
Multifactorial analysis of predictors of outcome in pediatric intracranial ependymoma. Neuro Oncol (2008) 1.33
Modulation of the cell growth regulator mTOR by Epstein-Barr virus-encoded LMP2A. J Virol (2005) 1.33
Epstein-Barr virus-encoded LMP2A regulates viral and cellular gene expression by modulation of the NF-kappaB transcription factor pathway. Proc Natl Acad Sci U S A (2004) 1.32
Down-regulation of the TGF-beta target gene, PTPRK, by the Epstein-Barr virus encoded EBNA1 contributes to the growth and survival of Hodgkin lymphoma cells. Blood (2007) 1.32
Role of the Epstein-Barr virus-encoded latent membrane protein-1, LMP1, in the pathogenesis of nasopharyngeal carcinoma. Future Oncol (2009) 1.31
Birth diagnosis of HIV infection in infants to reduce infant mortality and monitor for elimination of mother-to-child transmission. Pediatr Infect Dis J (2013) 1.30
Genomic sequence analysis of Epstein-Barr virus strain GD1 from a nasopharyngeal carcinoma patient. J Virol (2005) 1.30
Epstein-Barr virus (EBV) and its associated human cancers--genetics, epigenetics, pathobiology and novel therapeutics. Front Biosci (2006) 1.29
Constitutive activation of phosphatidyl-inositide 3 kinase contributes to the survival of Hodgkin's lymphoma cells through a mechanism involving Akt kinase and mTOR. J Pathol (2005) 1.27
Eight-signature classifier for prediction of nasopharyngeal [corrected] carcinoma survival. J Clin Oncol (2011) 1.23
Quantifying the species-specificity in genomic signatures, synonymous codon choice, amino acid usage and G+C content. Gene (2003) 1.22
Prognostic value of Bmi-1 oncoprotein expression in NSCLC patients: a tissue microarray study. J Cancer Res Clin Oncol (2008) 1.21
Proximity of first intercourse to menarche and the risk of human papillomavirus infection: a longitudinal study. Int J Cancer (2005) 1.20
Comparison of Epstein-Barr virus DNA level in plasma, peripheral blood cell and tumor tissue in nasopharyngeal carcinoma. Anticancer Res (2005) 1.20
Selective accumulation of virus-specific CD8+ T cells with unique homing phenotype within the human bone marrow. Blood (2008) 1.19
Epstein-Barr virus-encoded LMP1 regulates epithelial cell motility and invasion via the ERK-MAPK pathway. J Virol (2008) 1.18
Reactivity with A monoclonal antibody to Epstein-Barr virus (EBV) nuclear antigen 1 defines a subset of aggressive breast cancers in the absence of the EBV genome. Cancer Res (2003) 1.17
The molecular portrait of in vitro growth by meta-analysis of gene-expression profiles. Genome Biol (2005) 1.17
A phase I/II clinical trial in localized prostate cancer of an adenovirus expressing nitroreductase with CB1954 [correction of CB1984]. Mol Ther (2009) 1.16
Changes in expression of the human homologue of the Drosophila discs large tumour suppressor protein in high-grade premalignant cervical neoplasias. Carcinogenesis (2002) 1.12
XOMA 052, an anti-IL-1{beta} monoclonal antibody, improves glucose control and {beta}-cell function in the diet-induced obesity mouse model. Endocrinology (2010) 1.11
Disruption of the E2 gene is a common and early event in the natural history of cervical human papillomavirus infection: a longitudinal cohort study. Cancer Res (2009) 1.11
Absence of Epstein-Barr virus DNA in the tumor cells of European hepatocellular carcinoma. Virology (2003) 1.10
Inhibition of neuronal nitric oxide synthase by 7-nitroindazole attenuates acute lung injury in an ovine model. Am J Physiol Regul Integr Comp Physiol (2003) 1.10
CD8+ T cells specific for cancer germline gene antigens are found in many patients with multiple myeloma, and their frequency correlates with disease burden. Blood (2005) 1.10
Frequent RASSF1A tumour suppressor gene promoter methylation in Wilms' tumour and colorectal cancer. Oncogene (2002) 1.10
NotI subtraction and NotI-specific microarrays to detect copy number and methylation changes in whole genomes. Proc Natl Acad Sci U S A (2002) 1.10