Published in Endocrinology on March 23, 2010
Targeting interleukin-1 in heart disease. Circulation (2013) 2.52
Metabolic syndrome and insulin resistance: underlying causes and modification by exercise training. Compr Physiol (2013) 1.17
Reactive oxygen species at the crossroads of inflammasome and inflammation. Front Physiol (2014) 1.12
Adipose and liver expression of interleukin (IL)-1 family members in morbid obesity and effects of weight loss. Mol Med (2011) 1.06
The interleukin-1 receptor antagonist anakinra improves endothelial dysfunction in streptozotocin-induced diabetic rats. Cardiovasc Diabetol (2014) 1.02
Kinetic approach to pathway attenuation using XOMA 052, a regulatory therapeutic antibody that modulates interleukin-1beta activity. J Biol Chem (2010) 0.97
Connecting type 1 and type 2 diabetes through innate immunity. Cold Spring Harb Perspect Med (2012) 0.95
XOMA 052, a potent, high-affinity monoclonal antibody for the treatment of IL-1β-mediated diseases. MAbs (2011) 0.90
Interleukin-1β mediates macrophage-induced impairment of insulin signaling in human primary adipocytes. Am J Physiol Endocrinol Metab (2014) 0.89
Interleukin-1 as a common denominator from autoinflammatory to autoimmune disorders: premises, perils, and perspectives. Mediators Inflamm (2015) 0.89
Retracted Neutralizing interleukin-1beta (IL-1beta) induces beta-cell survival by maintaining PDX1 protein nuclear localization. J Biol Chem (2011) 0.88
Cyclooxygenase-2, not microsomal prostaglandin E synthase-1, is the mechanism for interleukin-1β-induced prostaglandin E2 production and inhibition of insulin secretion in pancreatic islets. J Biol Chem (2012) 0.87
Preclinical efficacy and safety of an anti-IL-1β vaccine for the treatment of type 2 diabetes. Mol Ther Methods Clin Dev (2014) 0.84
Red carpeting the newer antidiabetics. J Pharmacol Pharmacother (2012) 0.81
Knock-down of IL-1Ra in obese mice decreases liver inflammation and improves insulin sensitivity. PLoS One (2014) 0.80
Is interleukin-1β a culprit in macrophage-adipocyte crosstalk in obesity? Adipocyte (2015) 0.78
Microglia activation due to obesity programs metabolic failure leading to type two diabetes. Nutr Diabetes (2017) 0.78
Autophagy deficiency in myeloid cells increases susceptibility to obesity-induced diabetes and experimental colitis. Autophagy (2016) 0.77
Grape Seed Procyanidin Extract Improves Insulin Production but Enhances Bax Protein Expression in Cafeteria-Treated Male Rats. Int J Food Sci (2013) 0.75
The IL-1β Receptor Antagonist SER140 Postpones the Onset of Diabetes in Female Nonobese Diabetic Mice. J Diabetes Res (2016) 0.75
Interleukin-1β-Targeted Vaccine Improves Glucose Control and β-Cell Function in a Diabetic KK-Ay Mouse Model. PLoS One (2016) 0.75
Major liver resection results in early exacerbation of insulin resistance, and may be a risk factor of developing overt diabetes in the future. Surg Today (2012) 0.75
Colchicine to decrease NLRP3-activated inflammation and improve obesity-related metabolic dysregulation. Med Hypotheses (2016) 0.75
Angiopoetin-2 Signals Do Not Mediate the Hypervascularization of Islets in Type 2 Diabetes. PLoS One (2016) 0.75
Evaluation of the 8q24 prostate cancer risk locus and MYC expression. Cancer Res (2009) 2.54
Mechanisms of beta-cell death in type 2 diabetes. Diabetes (2005) 2.50
Decreased TCF7L2 protein levels in type 2 diabetes mellitus correlate with downregulation of GIP- and GLP-1 receptors and impaired beta-cell function. Hum Mol Genet (2009) 2.29
Retracted Transcription factor 7-like 2 regulates beta-cell survival and function in human pancreatic islets. Diabetes (2007) 2.25
Inflammatory mediators and islet beta-cell failure: a link between type 1 and type 2 diabetes. J Mol Med (Berl) (2003) 2.10
Monoclonal antibodies targeting IL-1 beta reduce biomarkers of atherosclerosis in vitro and inhibit atherosclerotic plaque formation in Apolipoprotein E-deficient mice. Atherosclerosis (2011) 1.96
Non-invasive detection of a small number of bioluminescent cancer cells in vivo. PLoS One (2010) 1.92
Combined burn and smoke inhalation injury impairs ovine hypoxic pulmonary vasoconstriction. Crit Care Med (2006) 1.77
The antiinflammatory cytokine interleukin-1 receptor antagonist protects from high-fat diet-induced hyperglycemia. Endocrinology (2008) 1.68
CXCL10 impairs beta cell function and viability in diabetes through TLR4 signaling. Cell Metab (2009) 1.55
Increased vascular access complications in patients with renal dysfunction undergoing percutaneous coronary procedures using arteriotomy closure devices. J Invasive Cardiol (2010) 1.52
Deletion of the mitochondrial flavoprotein apoptosis inducing factor (AIF) induces beta-cell apoptosis and impairs beta-cell mass. PLoS One (2009) 1.44
Sudden gains as a long-term predictor of treatment improvement among children in community mental health organizations. Behav Res Ther (2013) 1.43
Intravenous mesenchymal stem cell therapy early after reperfused acute myocardial infarction improves left ventricular function and alters electrophysiologic properties. Int J Cardiol (2005) 1.37
Angiopoietin 2 mediates microvascular and hemodynamic alterations in sepsis. J Clin Invest (2013) 1.32
Extracellular matrix protects pancreatic beta-cells against apoptosis: role of short- and long-term signaling pathways. Diabetes (2004) 1.31
Expression of the Epstein-Barr virus-encoded Epstein-Barr virus nuclear antigen 1 in Hodgkin's lymphoma cells mediates Up-regulation of CCL20 and the migration of regulatory T cells. Am J Pathol (2008) 1.29
TCF7L2 splice variants have distinct effects on beta-cell turnover and function. Hum Mol Genet (2011) 1.20
Antibodies to TWEAK receptor inhibit human tumor growth through dual mechanisms. Clin Cancer Res (2010) 1.14
Bacteremia and antimicrobial drug resistance over time, Ghana. Emerg Infect Dis (2011) 1.12
Inhibition of neuronal nitric oxide synthase by 7-nitroindazole attenuates acute lung injury in an ovine model. Am J Physiol Regul Integr Comp Physiol (2003) 1.10
The Fas pathway is involved in pancreatic beta cell secretory function. Proc Natl Acad Sci U S A (2007) 1.08
Rosiglitazone, a PPAR gamma agonist, attenuates inflammation after surgical brain injury in rodents. Brain Res (2008) 1.05
Airway house dust extract exposures modify allergen-induced airway hypersensitivity responses by TLR4-dependent and independent pathways. J Immunol (2008) 1.01
The diabetes-linked transcription factor Pax4 is expressed in human pancreatic islets and is activated by mitogens and GLP-1. Hum Mol Genet (2007) 1.01
Antidiabetic gliptins in combination with G-CSF enhances myocardial function and survival after acute myocardial infarction. Int J Cardiol (2013) 0.98
Oral delivery of tumor-targeting Salmonella exhibits promising therapeutic efficacy and low toxicity. Cancer Sci (2009) 0.98
The DPP-4 inhibitor linagliptin restores β-cell function and survival in human isolated islets through GLP-1 stabilization. J Clin Endocrinol Metab (2013) 0.96
AMPK activation through mitochondrial regulation results in increased substrate oxidation and improved metabolic parameters in models of diabetes. PLoS One (2013) 0.94
Pancreatic beta cells and islets take up thiamin by a regulated carrier-mediated process: studies using mice and human pancreatic preparations. Am J Physiol Gastrointest Liver Physiol (2009) 0.93
Alpha-2 adrenoceptor agonist protects retinal function after acute retinal ischemic injury in the rat. Vis Neurosci (2002) 0.92
The effectiveness of salvage surgery after the failure of primary concomitant chemoradiation in head and neck cancer. Otolaryngol Head Neck Surg (2007) 0.92
Expression of TweakR in breast cancer and preclinical activity of enavatuzumab, a humanized anti-TweakR mAb. J Cancer Res Clin Oncol (2012) 0.89
Proapoptotic effects of the chemokine, CXCL 10 are mediated by the noncognate receptor TLR4 in hepatocytes. Hepatology (2013) 0.88
UCP-2 and UCP-3 proteins are differentially regulated in pancreatic beta-cells. PLoS One (2008) 0.88
Retracted Neutralizing interleukin-1beta (IL-1beta) induces beta-cell survival by maintaining PDX1 protein nuclear localization. J Biol Chem (2011) 0.88
Anisotropy in the compressive mechanical properties of bovine cortical bone and the mineral and protein constituents. Acta Biomater (2011) 0.84
COUP-TFII controls mouse pancreatic β-cell mass through GLP-1-β-catenin signaling pathways. PLoS One (2012) 0.84
Efficient gene delivery and silencing of mouse and human pancreatic islets. BMC Biotechnol (2010) 0.83
Regenerative capacity of intravenous autologous, allogeneic and human mesenchymal stem cells in the infarcted pig myocardium-complicated by myocardial tumor formation. Scand Cardiovasc J (2009) 0.83
TLR2/6 and TLR4-activated macrophages contribute to islet inflammation and impair beta cell insulin gene expression via IL-1 and IL-6. Diabetologia (2014) 0.83
Genetic and biochemical evidence for a functional role of BACE1 in the regulation of insulin mRNA expression. Obesity (Silver Spring) (2013) 0.82
Imaging of the β-cells of the islets of Langerhans. Diabetes Res Clin Pract (2012) 0.82
Nuclear localization of c-FLIP-L and its regulation of AP-1 activity. Int J Biochem Cell Biol (2009) 0.82
Endoscopic nasopharyngectomy and its role in managing locally recurrent nasopharyngeal carcinoma. Otolaryngol Clin North Am (2011) 0.82
Expression of soluble, biologically active recombinant human endostatin in Escherichia coli. Protein Expr Purif (2005) 0.81
Brainstem and trigeminal nerve changes after radiosurgery for trigeminal pain. Surg Neurol (2006) 0.81
Ursolic acid inhibits cigarette smoke extract-induced human bronchial epithelial cell injury and prevents development of lung cancer. Molecules (2012) 0.81
Differences in mouse and human nonmemory B cell pools. J Immunol (2014) 0.80
Implanted auriculotemporal nerve stimulator for the treatment of refractory chronic migraine. Headache (2010) 0.80
Transcatheter treatment of severe tricuspid regurgitation using the edge-to-edge repair technique. EuroIntervention (2017) 0.79
Reactive oxygen species-mediated mitochondrial pathway is involved in Baohuoside I-induced apoptosis in human non-small cell lung cancer. Chem Biol Interact (2012) 0.79
A preclinical study on the efficacy and safety of a new vaccine against Coxsackievirus B1 reveals no risk for accelerated diabetes development in mouse models. Diabetologia (2014) 0.78
Expression of Fas but not Fas ligand on fetal pig beta cells. Xenotransplantation (2004) 0.78
Predictors of antiplatelet response to prasugrel during maintenance treatment. Platelets (2014) 0.78
The adipocytokine Nampt and its product NMN have no effect on beta-cell survival but potentiate glucose stimulated insulin secretion. PLoS One (2013) 0.78
Metabolism of tanshinone IIA, cryptotanshinone and tanshinone I from Radix Salvia miltiorrhiza in zebrafish. Molecules (2012) 0.77
Discovery and structure-activity relationship of 2-phenyl-oxazole-4-carboxamide derivatives as potent apoptosis inducers. Bioorg Med Chem Lett (2006) 0.77
Decreased TCF7L2 protein levels in type 2 diabetes mellitus correlate with downregulation of GIP- and GLP-1 receptors and impaired beta-cell function. Hum Mol Genet (2015) 0.77
Pyridoxalated haemoglobin polyoxyethylene conjugate, a nitric oxide scavenger, decreases dose-limiting hypotension associated with interleukin-2 (IL-2) therapy. Clin Sci (Lond) (2003) 0.77
CXCL10- a path to β-cell death. Islets (2010) 0.76
Global metabolite profiling of mice with high-fat diet-induced obesity chronically treated with AMPK activators R118 or metformin reveals tissue-selective alterations in metabolic pathways. BMC Res Notes (2014) 0.75
A Comment on Qi et al. An Estimation of Radiobiological Parameters for Head-and-Neck Cancer Cells and the Clinical Implications-Authors' Reply. Cancers (Basel) (2012) 0.75
Glucose-induced β cell production of IL-1β contributes to glucotoxicity in human pancreatic islets. J Clin Invest (2017) 0.75
Bleeding and thrombosis risk matters: how long can we stick to the one-size-fits-all strategy of platelet inhibition? JACC Cardiovasc Interv (2013) 0.75
Comparison of frequency of left ventricular wall motion abnormalities in patients with a first acute myocardial infarction with versus without left ventricular hypertrophy. Am J Cardiol (2004) 0.75
Prevention of cardiovascular events with antiplatelet treatment: does time of intake matter for aspirin and ADP receptor blockers? Thromb Haemost (2015) 0.75
Efficient chemoenzymatic synthesis of pelitrexol via enzymic differentiation of a remote stereocenter. Org Lett (2006) 0.75
Metabolite profiling of four major flavonoids of Herba Epimedii in zebrafish. Molecules (2012) 0.75
Diplopia on vorapaxar: An unexpected side effect emerging only at second glance. Thromb Haemost (2016) 0.75
[Induction and identification of autotetraploid plant of Platycodon grandiflorum]. Zhong Yao Cai (2002) 0.75
Neutralizing interleukin 1β (IL-1β) induces β-cell survival by maintaining PDX1 protein nuclear localization. J Biol Chem (2015) 0.75
Hand stiffness following distal radius fractures: who gets it and is it a functional problem? Bull Hosp Jt Dis (2013) (2014) 0.75
[Advance in studies on anti-diabetic mechanism of Gardeniae Fructus and its active ingredient geniposide]. Zhongguo Zhong Yao Za Zhi (2014) 0.75
Transcatheter Treatment of Severe Tricuspid Regurgitation Using the Edge-to-Edge Repair Technique in the Presence and Absence of Pacemaker Leads. JACC Cardiovasc Interv (2017) 0.75
Management of Completion and Total Thyroidectomy Patients Based on 1-Hour Postoperative Parathyroid Hormone. Am Surg (2016) 0.75
Six-Year Experience of Outpatient Total and Completion Thyroidectomy at a Single Academic Institution. Am Surg (2017) 0.75