Published in Mol Cell on June 06, 2008
Single-RNA counting reveals alternative modes of gene expression in yeast. Nat Struct Mol Biol (2008) 6.09
HSP90 and its R2TP/Prefoldin-like cochaperone are involved in the cytoplasmic assembly of RNA polymerase II. Mol Cell (2010) 2.07
Single-molecule tracking in live cells reveals distinct target-search strategies of transcription factors in the nucleus. Elife (2014) 1.80
Imaging transcription in living cells. Annu Rev Biophys (2009) 1.76
Stochastic and reversible assembly of a multiprotein DNA repair complex ensures accurate target site recognition and efficient repair. J Cell Biol (2010) 1.49
Transcriptional regulation by coactivators in embryonic stem cells. Trends Cell Biol (2012) 0.82
Nuclear physics: quantitative single-cell approaches to nuclear organization and gene expression. Cold Spring Harb Symp Quant Biol (2011) 0.81
A model for aryl hydrocarbon receptor-activated gene expression shows potency and efficacy changes and predicts squelching due to competition for transcription co-activators. PLoS One (2015) 0.75
In vivo dynamics of RNA polymerase II transcription. Nat Struct Mol Biol (2007) 6.10
Transcription regulation through promoter-proximal pausing of RNA polymerase II. Science (2008) 5.48
A kinetic framework for a mammalian RNA polymerase in vivo. Science (2002) 4.42
Intranuclear distribution and local dynamics of RNA polymerase II during transcription activation. Mol Cell (2007) 1.87
Condensed mitotic chromatin is accessible to transcription factors and chromatin structural proteins. J Cell Biol (2004) 1.86
Modulation of RNA polymerase assembly dynamics in transcriptional regulation. Mol Cell (2008) 1.47
Dynamics of transcription and mRNA export. Curr Opin Cell Biol (2005) 1.35
From silencing to gene expression: real-time analysis in single cells. Cell (2004) 7.73
Transcriptional pulsing of a developmental gene. Curr Biol (2006) 6.35
In vivo dynamics of RNA polymerase II transcription. Nat Struct Mol Biol (2007) 6.10
Single-RNA counting reveals alternative modes of gene expression in yeast. Nat Struct Mol Biol (2008) 6.09
Spatial regulation of beta-actin translation by Src-dependent phosphorylation of ZBP1. Nature (2005) 5.29
Single-cell gene expression profiling. Science (2002) 5.07
Dynamics of single mRNPs in nuclei of living cells. Science (2004) 4.58
Identification and testing of a gene expression signature of invasive carcinoma cells within primary mammary tumors. Cancer Res (2004) 4.04
Single cell behavior in metastatic primary mammary tumors correlated with gene expression patterns revealed by molecular profiling. Cancer Res (2002) 3.95
Gene expression and the myth of the average cell. Trends Cell Biol (2003) 3.78
Real-time observation of transcription initiation and elongation on an endogenous yeast gene. Science (2011) 3.67
Fluorescence in situ hybridization: past, present and future. J Cell Sci (2003) 3.20
The great escape: when cancer cells hijack the genes for chemotaxis and motility. Annu Rev Cell Dev Biol (2005) 2.97
Single-molecule mRNA decay measurements reveal promoter- regulated mRNA stability in yeast. Cell (2011) 2.92
Visualization of single molecules of mRNA in situ. Methods Enzymol (2003) 2.62
A direct role for FMRP in activity-dependent dendritic mRNA transport links filopodial-spine morphogenesis to fragile X syndrome. Dev Cell (2008) 2.51
How and why does beta-actin mRNA target? Biol Cell (2005) 2.38
Dynamic sorting of nuclear components into distinct nucleolar caps during transcriptional inhibition. Mol Biol Cell (2005) 2.36
Activity-dependent trafficking and dynamic localization of zipcode binding protein 1 and beta-actin mRNA in dendrites and spines of hippocampal neurons. J Neurosci (2003) 2.34
Active transport of the survival motor neuron protein and the role of exon-7 in cytoplasmic localization. J Neurosci (2003) 2.28
A transgenic mouse for in vivo detection of endogenous labeled mRNA. Nat Methods (2011) 2.27
The dynamics of mammalian P body transport, assembly, and disassembly in vivo. Mol Biol Cell (2008) 2.25
Single β-actin mRNA detection in neurons reveals a mechanism for regulating its translatability. Science (2014) 2.23
Two ZBP1 KH domains facilitate beta-actin mRNA localization, granule formation, and cytoskeletal attachment. J Cell Biol (2002) 2.20
Visualization of dynamics of single endogenous mRNA labeled in live mouse. Science (2014) 2.20
In vivo imaging of labelled endogenous β-actin mRNA during nucleocytoplasmic transport. Nature (2010) 2.16
Stepwise RNP assembly at the site of H/ACA RNA transcription in human cells. J Cell Biol (2006) 2.09
Asymmetric sorting of ash1p in yeast results from inhibition of translation by localization elements in the mRNA. Mol Cell (2002) 2.08
A new yeast PUF family protein, Puf6p, represses ASH1 mRNA translation and is required for its localization. Genes Dev (2004) 2.05
Real-time visualization of ZBP1 association with beta-actin mRNA during transcription and localization. Curr Biol (2003) 2.04
Visualization of mRNA translation in living cells. J Cell Biol (2006) 2.03
Localization of all seven messenger RNAs for the actin-polymerization nucleator Arp2/3 complex in the protrusions of fibroblasts. J Cell Sci (2005) 1.95
Imaging sites of N-wasp activity in lamellipodia and invadopodia of carcinoma cells. Curr Biol (2004) 1.91
ZBP1 regulates mRNA stability during cellular stress. J Cell Biol (2006) 1.84
Multiprotein complexes of the survival of motor neuron protein SMN with Gemins traffic to neuronal processes and growth cones of motor neurons. J Neurosci (2006) 1.80
Transcription of functionally related constitutive genes is not coordinated. Nat Struct Mol Biol (2010) 1.78
A predominantly nuclear protein affecting cytoplasmic localization of beta-actin mRNA in fibroblasts and neurons. J Cell Biol (2002) 1.77
Imaging transcription in living cells. Annu Rev Biophys (2009) 1.76
Localization of a beta-actin messenger ribonucleoprotein complex with zipcode-binding protein modulates the density of dendritic filopodia and filopodial synapses. J Neurosci (2003) 1.74
Structural basis for the coevolution of a viral RNA-protein complex. Nat Struct Mol Biol (2007) 1.71
A single molecule view of gene expression. Trends Cell Biol (2009) 1.69
The PTB interacting protein raver1 regulates alpha-tropomyosin alternative splicing. EMBO J (2003) 1.68
Pathways for mRNA localization in the cytoplasm. Trends Biochem Sci (2006) 1.66
Nuclear export dynamics of RNA-protein complexes. Nature (2011) 1.63
Variegated gene expression caused by cell-specific long-range DNA interactions. Nat Cell Biol (2011) 1.63
ZBP1 recognition of beta-actin zipcode induces RNA looping. Genes Dev (2010) 1.63
Single-molecule analysis of gene expression using two-color RNA labeling in live yeast. Nat Methods (2012) 1.62
Interactions of elongation factor 1alpha with F-actin and beta-actin mRNA: implications for anchoring mRNA in cell protrusions. Mol Biol Cell (2002) 1.60
Eukaryotic transcriptional dynamics: from single molecules to cell populations. Nat Rev Genet (2013) 1.57
Modern fluorescent proteins and imaging technologies to study gene expression, nuclear localization, and dynamics. Curr Opin Cell Biol (2011) 1.55
A peptide motif in Raver1 mediates splicing repression by interaction with the PTB RRM2 domain. Nat Struct Mol Biol (2006) 1.52
Translation of ASH1 mRNA is repressed by Puf6p-Fun12p/eIF5B interaction and released by CK2 phosphorylation. Genes Dev (2008) 1.50
Metabolic cycling in single yeast cells from unsynchronized steady-state populations limited on glucose or phosphate. Proc Natl Acad Sci U S A (2010) 1.44
Gene expression profiling in single cells within tissue. Nat Methods (2005) 1.43
YRA1 autoregulation requires nuclear export and cytoplasmic Edc3p-mediated degradation of its pre-mRNA. Mol Cell (2007) 1.43
RNA localization. J Cell Sci (2005) 1.39
Imaging gene expression in single living cells. Nat Rev Mol Cell Biol (2004) 1.39
Fluorescence fluctuation spectroscopy enables quantitative imaging of single mRNAs in living cells. Biophys J (2012) 1.37
She2p is a novel RNA binding protein with a basic helical hairpin motif. Cell (2004) 1.37
ZBP2 facilitates binding of ZBP1 to beta-actin mRNA during transcription. Mol Cell Biol (2007) 1.35
Dynamics of transcription and mRNA export. Curr Opin Cell Biol (2005) 1.35
The life of an mRNA in space and time. J Cell Sci (2010) 1.31
Mechanisms and cellular roles of local protein synthesis in mammalian cells. Curr Opin Cell Biol (2008) 1.31
Spatial arrangement of an RNA zipcode identifies mRNAs under post-transcriptional control. Genes Dev (2012) 1.26
The survival of motor neuron (SMN) protein interacts with the mRNA-binding protein HuD and regulates localization of poly(A) mRNA in primary motor neuron axons. J Neurosci (2011) 1.25
Promotion of importin alpha-mediated nuclear import by the phosphorylation-dependent binding of cargo protein to 14-3-3. J Cell Biol (2005) 1.23
Colocalization of different influenza viral RNA segments in the cytoplasm before viral budding as shown by single-molecule sensitivity FISH analysis. PLoS Pathog (2013) 1.23
RNA processing and export. Cold Spring Harb Perspect Biol (2010) 1.22
Measurement of barbed ends, actin polymerization, and motility in live carcinoma cells after growth factor stimulation. Cell Motil Cytoskeleton (2004) 1.21
IGF2BP1 promotes cell migration by regulating MK5 and PTEN signaling. Genes Dev (2012) 1.20
The nuclear connection in RNA transport and localization. Trends Cell Biol (2002) 1.20
Nuclear pore component Nup98 is a potential tumor suppressor and regulates posttranscriptional expression of select p53 target genes. Mol Cell (2012) 1.19
Temporal and spatial characterization of nonsense-mediated mRNA decay. Genes Dev (2013) 1.18
Stable morphology, but dynamic internal reorganisation, of interphase human chromosomes in living cells. PLoS One (2010) 1.17
Imaging mRNA movement from transcription sites to translation sites. Semin Cell Dev Biol (2007) 1.17
Developmental timing in Dictyostelium is regulated by the Set1 histone methyltransferase. Dev Biol (2006) 1.15
Single-mRNA counting using fluorescent in situ hybridization in budding yeast. Nat Protoc (2012) 1.15
β-Actin mRNA compartmentalization enhances focal adhesion stability and directs cell migration. Genes Dev (2012) 1.13
ZBP1 enhances cell polarity and reduces chemotaxis. J Cell Sci (2007) 1.11
Analyzing mRNA expression using single mRNA resolution fluorescent in situ hybridization. Methods Enzymol (2010) 1.11
Rrp17p is a eukaryotic exonuclease required for 5' end processing of Pre-60S ribosomal RNA. Mol Cell (2009) 1.10
Gene expression within a dynamic nuclear landscape. EMBO J (2006) 1.10
The fate of the messenger is pre-determined: a new model for regulation of gene expression. Biochim Biophys Acta (2013) 1.08
Assembling an intermediate filament network by dynamic cotranslation. J Cell Biol (2006) 1.08
Asymmetric distribution of nuclear pore complexes and the cytoplasmic localization of beta2-tubulin mRNA in Chlamydomonas reinhardtii. Dev Cell (2003) 1.07
Single mRNA tracking in live cells. Methods Enzymol (2010) 1.07
Transcription goes digital. EMBO Rep (2012) 1.06
Regulation of local expression of cell adhesion and motility-related mRNAs in breast cancer cells by IMP1/ZBP1. J Cell Sci (2012) 1.05
Feedback regulation between zipcode binding protein 1 and beta-catenin mRNAs in breast cancer cells. Mol Cell Biol (2008) 1.04
An unbiased analysis method to quantify mRNA localization reveals its correlation with cell motility. Cell Rep (2012) 1.03
Direct observation of frequency modulated transcription in single cells using light activation. Elife (2013) 1.03
Cell biology of mRNA decay. Methods Enzymol (2008) 1.02
Cotranscriptional effect of a premature termination codon revealed by live-cell imaging. RNA (2011) 1.02
An active precursor in assembly of yeast nuclear ribonuclease P. RNA (2002) 1.01
Dynamic association and localization of human H/ACA RNP proteins. RNA (2006) 1.01
Imaging of single mRNAs in the cytoplasm of living cells. Prog Mol Subcell Biol (2004) 0.99
mRNA on the move: the road to its biological destiny. J Biol Chem (2013) 0.99
Novel detection and differential utilization of a c-myc transcriptional block in colon cancer chemoprevention. Cancer Res (2002) 0.97
RNA asymmetric distribution and daughter/mother differentiation in yeast. Curr Opin Microbiol (2003) 0.97
Imaging translation in single cells using fluorescent microscopy. Cold Spring Harb Perspect Biol (2012) 0.93